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Meeting Abstracts

1089-P: Importance of Cardiorenal Complications for Prognosis in Persons with Type 1 Diabetes and Controls

SARA HALLSTRÖM, MAGNUS O. WIJKMAN, JOHNNY LUDVIGSSON, PER EKMAN, MARC A. PFEFFER, HANS WEDEL, ANNIKA ROSENGREN, MARCUS LIND
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1089-P
https://doi.org/10.2337/db22-1089-P
Published: 01 June 2022
View article titled, 1089-P: Importance of Cardiorenal Complications for Prognosis in Persons with Type 1 Diabetes and Controls
Journal Articles

Next-Generation HLA Sequence Analysis Uncovers Seven HLA-DQ Amino Acid Residues and Six Motifs Resistant to Childhood Type 1 Diabetes

Lue Ping Zhao, George K. Papadopoulos, William W. Kwok, Antonis K. Moustakas, George P. Bondinas, Annelie Carlsson, Helena Elding Larsson, Johnny Ludvigsson, Claude Marcus, Ulf Samuelsson, Ruihan Wang, Chul-Woo Pyo, Wyatt C. Nelson, Daniel E. Geraghty, Åke Lernmark
Journal: Diabetes
Diabetes 2020;69(11):2523–2535
https://doi.org/10.2337/db20-0374
Published: 31 August 2020
View article titled, Next-Generation HLA Sequence Analysis Uncovers Seven HLA-DQ Amino Acid Residues and Six Motifs Resistant to Childhood Type 1 Diabetes
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Meeting Abstracts

527-P: Risk Factors for Nephropathy among Children and Young Adults with Type 1 Diabetes: A Swedish Cohort

SHILAN S. AHMADI, ALDINA PIVODIC, ANN-MARIE SVENSSON, HANS WEDEL, JOHNNY LUDVIGSSON, MARCUS LIND
Journal: Diabetes
Diabetes 2020;69(Supplement_1):527-P
https://doi.org/10.2337/db20-527-P
Published: 01 June 2020
View article titled, 527-P: Risk Factors for Nephropathy among Children and Young Adults with Type 1 Diabetes: A Swedish Cohort
Journal Articles

Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association With the Risk of Type 1 Diabetes in DQ2 and DQ8 Children

Lue Ping Zhao, George K. Papadopoulos, William W. Kwok, Antonis K. Moustakas, George P. Bondinas, Helena Elding Larsson, Johnny Ludvigsson, Claude Marcus, Ulf Samuelsson, Ruihan Wang, Chul-Woo Pyo, Wyatt C. Nelson, Daniel E. Geraghty, Åke Lernmark
Journal: Diabetes
Diabetes 2020;69(7):1573–1587
https://doi.org/10.2337/db20-0075
Published: 03 April 2020
View article titled, Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association With the Risk of Type 1 Diabetes in DQ2 and DQ8 Children
Open the PDF for Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association With the Risk of Type 1 Diabetes in DQ2 and DQ8 Children in another window
Journal Articles

Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4, and 5 Include Potentially Causal Residues Responsible for the Risk of Childhood Type 1 Diabetes

Lue Ping Zhao, George K. Papadopoulos, William W. Kwok, Bryan Xu, Matthew Kong, Antonis K. Moustakas, George P. Bondinas, Annelie Carlsson, Helena Elding-Larsson, Johnny Ludvigsson, Claude Marcus, Martina Persson, Ulf Samuelsson, Ruihan Wang, Chul-Woo Pyo, Wyatt C. Nelson, Daniel E. Geraghty, Åke Lernmark
Journal: Diabetes
Diabetes 2019;68(8):1692–1704
https://doi.org/10.2337/db19-0273
Published: 24 May 2019
View article titled, Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4, and 5 Include Potentially Causal Residues Responsible for the Risk of Childhood Type 1 Diabetes
Open the PDF for Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4, and 5 Include Potentially Causal Residues Responsible for the Risk of Childhood Type 1 Diabetes in another window
Includes: Multimedia, Supplementary data
Journal Articles

Genetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes

Özkan Aydemir, Janelle A. Noble, Jeffrey A. Bailey, Åke Lernmark, Patrick Marsh, Agnes Andersson Svärd, Frank Bearoff, Elizabeth P. Blankenhorn, John P. Mordes, Better Diabetes Diagnosis (BDD) Study Group, Martina Persson, Helena Elding Larsson, Gun Forsander, Sten-Anders Ivarsson, Johnny Ludvigsson, Claude Marcus, Annelie Carlsson
Journal: Diabetes
Diabetes 2019;68(7):1523–1527
https://doi.org/10.2337/db18-1128
Published: 08 April 2019
View article titled, Genetic Variation Within the <em>HLA-DRA1</em> Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes
Open the PDF for Genetic Variation Within the <em>HLA-DRA1</em> Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes in another window
Includes: Supplementary data
Meeting Abstracts

Genetic Risk for Type 1 Diabetes Profoundly Influences the Core Gut Microbiome in Children

JORDAN RUSSELL, LUIZ ROESCH, MARK A. ATKINSON, DESMOND SCHATZ, ERIC W. TRIPLETT, JOHNNY LUDVIGSSON
Journal: Diabetes
Diabetes 2018;67(Supplement_1):209-LB
https://doi.org/10.2337/db18-209-LB
Published: 01 July 2018
View article titled, Genetic Risk for Type 1 Diabetes Profoundly Influences the Core Gut Microbiome in Children
Journal Articles

Next-Generation Sequencing Reveals That HLA-DRB3, -DRB4, and -DRB5 May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes

Lue Ping Zhao, Shehab Alshiekh, Michael Zhao, Annelie Carlsson, Helena Elding Larsson, Gun Forsander, Sten A. Ivarsson, Johnny Ludvigsson, Ingrid Kockum, Claude Marcus, Martina Persson, Ulf Samuelsson, Eva Örtqvist, Chul-Woo Pyo, Wyatt C. Nelson, Daniel E. Geraghty, Åke Lernmark, for the Better Diabetes Diagnosis (BDD) Study Group
Journal: Diabetes
Diabetes 2016;65(3):710–718
https://doi.org/10.2337/db15-1115
Published: 06 January 2016
View article titled, Next-Generation Sequencing Reveals That <em>HLA-DRB3</em>, <em>-DRB4</em>, and <em>-DRB5</em> May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes
Open the PDF for Next-Generation Sequencing Reveals That <em>HLA-DRB3</em>, <em>-DRB4</em>, and <em>-DRB5</em> May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes in another window
Journal Articles

Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study

Lars Krogvold, Oskar Skog, Görel Sundström, Bjørn Edwin, Trond Buanes, Kristian F. Hanssen, Johnny Ludvigsson, Manfred Grabherr, Olle Korsgren, Knut Dahl-Jørgensen
Journal: Diabetes
Diabetes 2015;64(7):2506–2512
https://doi.org/10.2337/db14-1911
Published: 12 February 2015
View article titled, Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: <subtitle>Results From the DiViD Study</subtitle>
Open the PDF for Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: <subtitle>Results From the DiViD Study</subtitle> in another window
Includes: Supplementary data
Journal Articles

Detection of a Low-Grade Enteroviral Infection in the Islets of Langerhans of Living Patients Newly Diagnosed With Type 1 Diabetes

Lars Krogvold, Bjørn Edwin, Trond Buanes, Gun Frisk, Oskar Skog, Mahesh Anagandula, Olle Korsgren, Dag Undlien, Morten C. Eike, Sarah J. Richardson, Pia Leete, Noel G. Morgan, Sami Oikarinen, Maarit Oikarinen, Jutta E. Laiho, Heikki Hyöty, Johnny Ludvigsson, Kristian F. Hanssen, Knut Dahl-Jørgensen
Journal: Diabetes
Diabetes 2015;64(5):1682–1687
https://doi.org/10.2337/db14-1370
Published: 24 November 2014
View article titled, Detection of a Low-Grade Enteroviral Infection in the Islets of Langerhans of Living Patients Newly Diagnosed With Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Virus Antibody Survey in Different European Populations Indicates Risk Association Between Coxsackievirus B1 and Type 1 Diabetes

Sami Oikarinen, Sisko Tauriainen, Didier Hober, Bernadette Lucas, Andriani Vazeou, Amirbabak Sioofy-Khojine, Evangelos Bozas, Peter Muir, Hanna Honkanen, Jorma Ilonen, Mikael Knip, Päivi Keskinen, Marja-Terttu Saha, Heini Huhtala, Glyn Stanway, Christos Bartsocas, Johnny Ludvigsson, Keith Taylor, Heikki Hyöty, the VirDiab Study Group
Journal: Diabetes
Diabetes 2014;63(2):655–662
https://doi.org/10.2337/db13-0620
Published: 16 January 2014
View article titled, Virus Antibody Survey in Different European Populations Indicates Risk Association Between Coxsackievirus B1 and Type 1 Diabetes
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Journal Articles

Teplizumab Preserves C-Peptide in Recent-Onset Type 1 Diabetes: Two-Year Results From the Randomized, Placebo-Controlled Protégé Trial

William Hagopian, Robert J. Ferry, Jr., Nicole Sherry, David Carlin, Ezio Bonvini, Syd Johnson, Kathryn E. Stein, Scott Koenig, Anastasia G. Daifotis, Kevan C. Herold, Johnny Ludvigsson, for the Protégé Trial Investigators
Journal: Diabetes
Diabetes 2013;62(11):3901–3908
https://doi.org/10.2337/db13-0236
Published: 18 October 2013
View article titled, Teplizumab Preserves C-Peptide in Recent-Onset Type 1 Diabetes: <subtitle>Two-Year Results From the Randomized, Placebo-Controlled Protégé Trial</subtitle>
Open the PDF for Teplizumab Preserves C-Peptide in Recent-Onset Type 1 Diabetes: <subtitle>Two-Year Results From the Randomized, Placebo-Controlled Protégé Trial</subtitle> in another window
Includes: Supplementary data
Journal Articles

Zinc Transporter 8 Autoantibodies and Their Association With SLC30A8 and HLA-DQ Genes Differ Between Immigrant and Swedish Patients With Newly Diagnosed Type 1 Diabetes in the Better Diabetes Diagnosis Study

Ahmed J. Delli, Fariba Vaziri-Sani, Bengt Lindblad, Helena Elding-Larsson, Annelie Carlsson, Gun Forsander, Sten A. Ivarsson, Johnny Ludvigsson, Ingrid Kockum, Claude Marcus, Ulf Samuelsson, Eva Örtqvist, Leif Groop, George P. Bondinas, George K. Papadopoulos, Åke Lernmark, for the Better Diabetes Diagnosis Study Group
Journal: Diabetes
Diabetes 2012;61(10):2556–2564
https://doi.org/10.2337/db11-1659
Published: 13 September 2012
View article titled, Zinc Transporter 8 Autoantibodies and Their Association With <em>SLC30A8</em> and <em>HLA-DQ</em> Genes Differ Between Immigrant and Swedish Patients With Newly Diagnosed Type 1 Diabetes in the Better Diabetes Diagnosis Study
Open the PDF for Zinc Transporter 8 Autoantibodies and Their Association With <em>SLC30A8</em> and <em>HLA-DQ</em> Genes Differ Between Immigrant and Swedish Patients With Newly Diagnosed Type 1 Diabetes in the Better Diabetes Diagnosis Study in another window
Includes: Supplementary data
Journal Articles

Interbirth Interval Is Associated With Childhood Type 1 Diabetes Risk

Chris R. Cardwell, Jannet Svensson, Thomas Waldhoer, Johnny Ludvigsson, Vaiva Sadauskaitė-Kuehne, Christine L. Roberts, Roger C. Parslow, Emma J.K. Wadsworth, Girts Brigis, Brone Urbonaitė, Edith Schober, Gabriele Devoti, Constantin Ionescu-Tirgoviste, Carine E. de Beaufort, Gyula Soltesz, Chris C. Patterson
Journal: Diabetes
Diabetes 2012;61(3):702–707
https://doi.org/10.2337/db11-1000
Published: 13 February 2012
View article titled, Interbirth Interval Is Associated With Childhood Type 1 Diabetes Risk
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Journal Articles

Maternal Age at Birth and Childhood Type 1 Diabetes: A Pooled Analysis of 30 Observational Studies

Chris R. Cardwell, Lars C. Stene, Geir Joner, Max K. Bulsara, Ondrej Cinek, Joachim Rosenbauer, Johnny Ludvigsson, Mireia Jané, Jannet Svensson, Michael J. Goldacre, Thomas Waldhoer, Przemysława Jarosz-Chobot, Suely G.A. Gimeno, Lee-Ming Chuang, Roger C. Parslow, Emma J.K. Wadsworth, Amanda Chetwynd, Paolo Pozzilli, Girts Brigis, Brone Urbonaitė, Sandra Šipetić, Edith Schober, Gabriele Devoti, Constantin Ionescu-Tirgoviste, Carine E. de Beaufort, Denka Stoyanov, Karsten Buschard, Chris C. Patterson
Journal: Diabetes
Diabetes 2010;59(2):486–494
https://doi.org/10.2337/db09-1166
Published: 29 October 2009
View article titled, Maternal Age at Birth and Childhood Type 1 Diabetes: A Pooled Analysis of 30 Observational Studies
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Journal Articles

Decreased In Vitro Type 1 Immune Response Against Coxsackie Virus B4 in Children With Type 1 Diabetes

Susanne Skarsvik, Julia Puranen, Jarno Honkanen, Merja Roivainen, Jorma Ilonen, Hanna Holmberg, Johnny Ludvigsson, Outi Vaarala
Journal: Diabetes
Diabetes 2006;55(4):996–1003
https://doi.org/10.2337/diabetes.55.04.06.db05-0630
Published: 01 April 2006
View article titled, Decreased In Vitro Type 1 Immune Response Against Coxsackie Virus B4 in Children With Type 1 Diabetes
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Journal Articles

A Prospective Analysis of Islet-cell Cytotoxic Antibodies in Insulin-dependent Diabetic Children: Transient Effects of Plasmapheresis

Alexander Rabinovitch, Peter MacKay, Johnny Ludvigsson, Åke Lernmark
Journal: Diabetes
Diabetes 1984;33(3):224–228
https://doi.org/10.2337/diab.33.3.224
Published: 01 March 1984
View article titled, A Prospective Analysis of Islet-cell Cytotoxic Antibodies in Insulin-dependent Diabetic Children: Transient Effects of Plasmapheresis
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Journal Articles

Immunoglobulin from Insulin-dependent Diabetic Children Inhibits Glucose-induced Insulin Release

Takahiro Kanatsuna, Steinunn Bæekkeskov, Åke Lernmark, Johnny Ludvigsson
Journal: Diabetes
Diabetes 1983;32(6):520–524
https://doi.org/10.2337/diab.32.6.520
Published: 01 June 1983
View article titled, Immunoglobulin from Insulin-dependent Diabetic Children Inhibits Glucose-induced Insulin Release
Open the PDF for Immunoglobulin from Insulin-dependent Diabetic Children Inhibits Glucose-induced Insulin Release in another window