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Josephine M. Forbes
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Journal Articles

Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells

Free
Sherman S. Leung, Danielle J. Borg, Domenica A. McCarthy, Tamar E. Boursalian, Justen Cracraft, Aowen Zhuang, Amelia K. Fotheringham, Nicole Flemming, Thomas Watkins, John J. Miles, Per-Henrik Groop, Jean L. Scheijen, Casper G. Schalkwijk, Raymond J. Steptoe, Kristen J. Radford, Mikael Knip, Josephine M. Forbes
Journal: Diabetes
Diabetes 2022;71(9):1994–2008
https://doi.org/10.2337/db22-0177
Published: 17 June 2022
View article titled, Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells
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Journal Articles

T-Cell Expression and Release of Kidney Injury Molecule-1 in Response to Glucose Variations Initiates Kidney Injury in Early Diabetes

Free
Josephine M. Forbes, Domenica A. McCarthy, Andrew J. Kassianos, Tracey Baskerville, Amelia K. Fotheringham, Kurt T.K. Giuliani, Anca Grivei, Andrew J. Murphy, Michelle C. Flynn, Mitchell A. Sullivan, Preeti Chandrashekar, Rani Whiddett, Kristen J. Radford, Nicole Flemming, Sam S. Beard, Neisha D’Silva, Janelle Nisbet, Adam Morton, Stephanie Teasdale, Anthony Russell, Nicole Isbel, Timothy Jones, Jennifer Couper, Helen Healy, Mark Harris, Kim Donaghue, David W. Johnson, Andrew Cotterill, Helen L. Barrett, Trisha O’Moore-Sullivan
Journal: Diabetes
Diabetes 2021;70(8):1754–1766
https://doi.org/10.2337/db20-1081
Published: 18 March 2021
View article titled, T-Cell Expression and Release of Kidney Injury Molecule-1 in Response to Glucose Variations Initiates Kidney Injury in Early Diabetes
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Journal Articles

Going in Early: Hypoxia as a Target for Kidney Disease Prevention in Diabetes?

Free
Helen L. Barrett, Kim C. Donaghue, Josephine M. Forbes
Journal: Diabetes
Diabetes 2020;69(12):2578–2580
https://doi.org/10.2337/dbi20-0037
Published: 16 November 2020
View article titled, Going in Early: Hypoxia as a Target for Kidney Disease Prevention in Diabetes?
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Journal Articles

Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility

Free
Sih Min Tan, Mark Ziemann, Vicki Thallas-Bonke, Matthew Snelson, Vinod Kumar, Adrienne Laskowski, Tuong-Vi Nguyen, Kevin Huynh, Michele V. Clarke, Renata Libianto, Scott T. Baker, Alison Skene, David A. Power, Richard J. MacIsaac, Darren C. Henstridge, Rick A. Wetsel, Assam El-Osta, Peter J. Meikle, Scott G. Wilson, Josephine M. Forbes, Mark E. Cooper, Elif I. Ekinci, Trent M. Woodruff, Melinda T. Coughlan
Journal: Diabetes
Diabetes 2020;69(1):83–98
https://doi.org/10.2337/db19-0043
Published: 17 October 2019
View article titled, Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility
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Includes: Supplementary data
Journal Articles

Antigen-Encoding Bone Marrow Terminates Islet-Directed Memory CD8+ T-Cell Responses to Alleviate Islet Transplant Rejection

Free
Miranda A. Coleman, Claire F. Jessup, Jennifer A. Bridge, Nana H. Overgaard, Daniella Penko, Stacey Walters, Danielle J. Borg, Ryan Galea, Josephine M. Forbes, Ranjeny Thomas, Patrick T.C. Coates, Shane T. Grey, James W. Wells, Raymond J. Steptoe
Journal: Diabetes
Diabetes 2016;65(5):1328–1340
https://doi.org/10.2337/db15-1418
Published: 09 March 2016
View article titled, Antigen-Encoding Bone Marrow Terminates Islet-Directed Memory CD8+ T-Cell Responses to Alleviate Islet Transplant Rejection
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Includes: Supplementary data
Journal Articles

Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis

Free
Melinda T. Coughlan, Gavin C. Higgins, Tuong-Vi Nguyen, Sally A. Penfold, Vicki Thallas-Bonke, Sih Min Tan, Georg Ramm, Nicole J. Van Bergen, Darren C. Henstridge, Karly C. Sourris, Brooke E. Harcourt, Ian A. Trounce, Portia M. Robb, Adrienne Laskowski, Sean L. McGee, Amanda J. Genders, Ken Walder, Brian G. Drew, Paul Gregorevic, Hongwei Qian, Merlin C. Thomas, George Jerums, Richard J. Macisaac, Alison Skene, David A. Power, Elif I. Ekinci, Xiaonan W. Wijeyeratne, Linda A. Gallo, Michal Herman-Edelstein, Michael T. Ryan, Mark E. Cooper, David R. Thorburn, Josephine M. Forbes
Journal: Diabetes
Diabetes 2016;65(4):1085–1098
https://doi.org/10.2337/db15-0864
Published: 28 January 2016
View article titled, Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis
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Includes: Supplementary data
Journal Articles

Type 2 Diabetes, Skin Autofluorescence, and Brain Atrophy

Free
Chris Moran, Gerald Münch, Josephine M. Forbes, Richard Beare, Leigh Blizzard, Alison J. Venn, Thanh G. Phan, Jian Chen, Velandai Srikanth
Journal: Diabetes
Diabetes 2015;64(1):279–283
https://doi.org/10.2337/db14-0506
Published: 22 July 2014
View article titled, Type 2 Diabetes, Skin Autofluorescence, and Brain Atrophy
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Includes: Supplementary data
Journal Articles

Advanced Glycation End Products Are Direct Modulators of β-Cell Function

Open Access
Melinda T. Coughlan, Felicia Y.T. Yap, David C.K. Tong, Sofianos Andrikopoulos, Anna Gasser, Vicki Thallas-Bonke, Diane E. Webster, Jun-ichi Miyazaki, Thomas W. Kay, Robyn M. Slattery, David M. Kaye, Brian G. Drew, Bronwyn A. Kingwell, Spiros Fourlanos, Per-Henrik Groop, Leonard C. Harrison, Mikael Knip, Josephine M. Forbes
Journal: Diabetes
Diabetes 2011;60(10):2523–2532
https://doi.org/10.2337/db10-1033
Published: 16 September 2011
View article titled, Advanced Glycation End Products Are Direct Modulators of β-Cell Function
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Includes: Supplementary data
Journal Articles

c-Jun NH2-Terminal Kinase Activity in Subcutaneous Adipose Tissue but Not Nuclear Factor-κB Activity in Peripheral Blood Mononuclear Cells Is an Independent Determinant of Insulin Resistance in Healthy Individuals

Open Access
Karly C. Sourris, Jasmine G. Lyons, Maximilian P.J. de Courten, Sonia L. Dougherty, Darren C. Henstridge, Mark E. Cooper, Michelle Hage, Anthony Dart, Bronwyn A. Kingwell, Josephine M. Forbes, Barbora de Courten
Journal: Diabetes
Diabetes 2009;58(6):1259–1265
https://doi.org/10.2337/db08-1725
Published: 03 March 2009
View article titled, c-Jun NH2-Terminal Kinase Activity in Subcutaneous Adipose Tissue but Not Nuclear Factor-κB Activity in Peripheral Blood Mononuclear Cells Is an Independent Determinant of Insulin Resistance in Healthy Individuals
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Journal Articles

Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes

Free
Aino Soro-Paavonen, Anna M.D. Watson, Jiaze Li, Karri Paavonen, Audrey Koitka, Anna C. Calkin, David Barit, Melinda T. Coughlan, Brian G. Drew, Graeme I. Lancaster, Merlin Thomas, Josephine M. Forbes, Peter P. Nawroth, Angelika Bierhaus, Mark E. Cooper, Karin A. Jandeleit-Dahm
Journal: Diabetes
Diabetes 2008;57(9):2461–2469
https://doi.org/10.2337/db07-1808
Published: 01 September 2008
View article titled, Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes
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Includes: Supplementary data
Journal Articles

Response to Comment on: Thallas-Bonke et al. (2008) Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway: Diabetes 57:460–469, 2008

Free
Vicki Thallas-Bonke, Josephine M. Forbes
Journal: Diabetes
Diabetes 2008;57(6):e14
https://doi.org/10.2337/db08-0406
Published: 01 June 2008
View article titled, Response to Comment on: Thallas-Bonke et al. (2008) Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway: Diabetes 57:460–469, 2008
Open the PDF for Response to Comment on: Thallas-Bonke et al. (2008) Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway: Diabetes 57:460–469, 2008 in another window
Journal Articles

Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes

Free
Josephine M. Forbes, Melinda T. Coughlan, Mark E. Cooper
Journal: Diabetes
Diabetes 2008;57(6):1446–1454
https://doi.org/10.2337/db08-0057
Published: 01 June 2008
View article titled, Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes
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Journal Articles

Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway

Free
Vicki Thallas-Bonke, Suzanne R. Thorpe, Melinda T. Coughlan, Kei Fukami, Felicia Y.T. Yap, Karly C. Sourris, Sally A. Penfold, Leon A. Bach, Mark E. Cooper, Josephine M. Forbes
Journal: Diabetes
Diabetes 2008;57(2):460–469
https://doi.org/10.2337/db07-1119
Published: 01 February 2008
View article titled, Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway
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Journal Articles

Attenuation of Extracellular Matrix Accumulation in Diabetic Nephropathy by the Advanced Glycation End Product Cross-Link Breaker ALT-711 via a Protein Kinase C-α−Dependent Pathway

Free
Vicki Thallas-Bonke, Carsten Lindschau, Bishoy Rizkalla, Leon A. Bach, Geoffrey Boner, Matthias Meier, Hermann Haller, Mark E. Cooper, Josephine M. Forbes
Journal: Diabetes
Diabetes 2004;53(11):2921–2930
https://doi.org/10.2337/diabetes.53.11.2921
Published: 01 November 2004
View article titled, Attenuation of Extracellular Matrix Accumulation in Diabetic Nephropathy by the Advanced Glycation End Product Cross-Link Breaker ALT-711 via a Protein Kinase C-α−Dependent Pathway
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Journal Articles

Advanced Glycation End Product Interventions Reduce Diabetes-Accelerated Atherosclerosis

Free
Josephine M. Forbes, Louis Teo Loon Yee, Vicki Thallas, Markus Lassila, Riccardo Candido, Karin A. Jandeleit-Dahm, Merlin C. Thomas, Wendy C. Burns, Elizabeth K. Deemer, Susan R. Thorpe, Mark E. Cooper, Terri J. Allen
Journal: Diabetes
Diabetes 2004;53(7):1813–1823
https://doi.org/10.2337/diabetes.53.7.1813
Published: 01 July 2004
View article titled, Advanced Glycation End Product Interventions Reduce Diabetes-Accelerated Atherosclerosis
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Journal Articles

Reduction of the Accumulation of Advanced Glycation End Products by ACE Inhibition in Experimental Diabetic Nephropathy

Free
Josephine M. Forbes, Mark E. Cooper, Vicki Thallas, Wendy C. Burns, Merlin C. Thomas, Gail C. Brammar, Fiona Lee, Sharon L. Grant, Louise M. Burrell, George Jerums, Tanya M. Osicka
Journal: Diabetes
Diabetes 2002;51(11):3274–3282
https://doi.org/10.2337/diabetes.51.11.3274
Published: 01 November 2002
View article titled, Reduction of the Accumulation of Advanced Glycation End Products by ACE Inhibition in Experimental Diabetic Nephropathy
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