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Juleen R. Zierath
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Meeting Abstracts

289-OR: Defining Pathway-Selective Insulin Resistance in Type 2 Diabetes Using iPS Cell-Derived Hepatocytes

ARIJEET GATTU, ANNA KROOK, JULEEN R. ZIERATH, MATTHIAS MANN, C. RONALD KAHN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):289-OR
https://doi.org/10.2337/db23-289-OR
Published: 20 June 2023
View article titled, 289-OR: Defining Pathway-Selective Insulin Resistance in Type 2 Diabetes Using iPS Cell-Derived Hepatocytes
Journal Articles

Glutamine Regulates Skeletal Muscle Immunometabolism in Type 2 Diabetes

Lucile Dollet, Michael Kuefner, Elena Caria, David Rizo-Roca, Logan Pendergrast, Ahmed M. Abdelmoez, Håkan K.R. Karlsson, Marie Bjrnholm, Emilie Dalbram, Jonas T. Treebak, Jun Harada, Erik Näslund, Mikael Rydén, Juleen R. Zierath, Nicolas J. Pillon, Anna Krook
Journal: Diabetes
Diabetes 2022;71(4):624–636
https://doi.org/10.2337/db20-0814
Published: 18 January 2022
View article titled, Glutamine Regulates Skeletal Muscle Immunometabolism in Type 2 Diabetes
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Meeting Abstracts

298-OR: Disruption of Multiple Cell-Autonomous Protein Phosphorylation Networks Underlies Muscle Insulin Resistance in Type 2 Diabetes

THIAGO M. BATISTA, NICOLAI J. WEWER ALBRECHTSEN, JULEEN R. ZIERATH, MATTHIAS MANN, C. RONALD KAHN
Journal: Diabetes
Diabetes 2020;69(Supplement_1):298-OR
https://doi.org/10.2337/db20-298-OR
Published: 01 June 2020
View article titled, 298-OR: Disruption of Multiple Cell-Autonomous Protein Phosphorylation Networks Underlies Muscle Insulin Resistance in Type 2 Diabetes
Journal Articles

Modified UCN2 Peptide Acts as an Insulin Sensitizer in Skeletal Muscle of Obese Mice

Melissa L. Borg, Julie Massart, Milena Schönke, Thais De Castro Barbosa, Lili Guo, Mark Wade, Jorge Alsina-Fernandez, Rebecca Miles, Andrew Ryan, Steve Bauer, Tamer Coskun, Elizabeth O’Farrell, Evan M. Niemeier, Alexander V. Chibalin, Anna Krook, Håkan K. Karlsson, Joseph T. Brozinick, Juleen R. Zierath
Journal: Diabetes
Diabetes 2019;68(7):1403–1414
https://doi.org/10.2337/db18-1237
Published: 22 April 2019
View article titled, Modified UCN2 Peptide Acts as an Insulin Sensitizer in Skeletal Muscle of Obese Mice
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Includes: Supplementary data
Journal Articles

Circulating Exosomal miR-20b-5p Is Elevated in Type 2 Diabetes and Could Impair Insulin Action in Human Skeletal Muscle

Mutsumi Katayama, Oscar P.B. Wiklander, Tomas Fritz, Kenneth Caidahl, Samir El-Andaloussi, Juleen R. Zierath, Anna Krook
Journal: Diabetes
Diabetes 2019;68(3):515–526
https://doi.org/10.2337/db18-0470
Published: 14 December 2018
View article titled, Circulating Exosomal miR-20b-5p Is Elevated in Type 2 Diabetes and Could Impair Insulin Action in Human Skeletal Muscle
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Includes: Supplementary data
Meeting Abstracts

Modeling the Spectrum of Human Insulin Resistance Using Induced Pluripotent Stem Cells

JASMIN LEBASTCHI, THIAGO M. BATISTA, IVAN CARCAMO-ORIVE, ANNA KROOK, JULEEN R. ZIERATH, JOSH KNOWLES, C. RONALD KAHN
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1784-P
https://doi.org/10.2337/db18-1784-P
Published: 01 July 2018
View article titled, Modeling the Spectrum of Human Insulin Resistance Using Induced Pluripotent Stem Cells
Journal Articles

Altered miR-29 Expression in Type 2 Diabetes Influences Glucose and Lipid Metabolism in Skeletal Muscle

Julie Massart, Rasmus J.O. Sjögren, Leonidas S. Lundell, Jonathan M. Mudry, Niclas Franck, Donal J. O’Gorman, Brendan Egan, Juleen R. Zierath, Anna Krook
Journal: Diabetes
Diabetes 2017;66(7):1807–1818
https://doi.org/10.2337/db17-0141
Published: 12 April 2017
View article titled, Altered miR-29 Expression in Type 2 Diabetes Influences Glucose and Lipid Metabolism in Skeletal Muscle
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Includes: Supplementary data
Journal Articles

Insulin and Glucose Alter Death-Associated Protein Kinase 3 (DAPK3) DNA Methylation in Human Skeletal Muscle

Jonathan M. Mudry, David G. Lassiter, Carolina Nylén, Sonia García-Calzón, Erik Näslund, Anna Krook, Juleen R. Zierath
Journal: Diabetes
Diabetes 2017;66(3):651–662
https://doi.org/10.2337/db16-0882
Published: 23 December 2016
View article titled, Insulin and Glucose Alter Death-Associated Protein Kinase 3 (DAPK3) DNA Methylation in Human Skeletal Muscle
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Includes: Supplementary data
Journal Articles

Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK

Rasmus Kjøbsted, Nanna Munk-Hansen, Jesper B. Birk, Marc Foretz, Benoit Viollet, Marie Björnholm, Juleen R. Zierath, Jonas T. Treebak, Jørgen F.P. Wojtaszewski
Journal: Diabetes
Diabetes 2017;66(3):598–612
https://doi.org/10.2337/db16-0530
Published: 24 October 2016
View article titled, Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK
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Journal Articles

Prior AICAR Stimulation Increases Insulin Sensitivity in Mouse Skeletal Muscle in an AMPK-Dependent Manner

Rasmus Kjøbsted, Jonas T. Treebak, Joachim Fentz, Louise Lantier, Benoit Viollet, Jesper B. Birk, Peter Schjerling, Marie Björnholm, Juleen R. Zierath, Jørgen F.P. Wojtaszewski
Journal: Diabetes
Diabetes 2015;64(6):2042–2055
https://doi.org/10.2337/db14-1402
Published: 31 December 2014
View article titled, Prior AICAR Stimulation Increases Insulin Sensitivity in Mouse Skeletal Muscle in an AMPK-Dependent Manner
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Journal Articles

Methotrexate Promotes Glucose Uptake and Lipid Oxidation in Skeletal Muscle via AMPK Activation

Sergej Pirkmajer, Sameer S. Kulkarni, Robby Z. Tom, Fiona A. Ross, Simon A. Hawley, D. Grahame Hardie, Juleen R. Zierath, Alexander V. Chibalin
Journal: Diabetes
Diabetes 2015;64(2):360–369
https://doi.org/10.2337/db14-0508
Published: 22 October 2014
View article titled, Methotrexate Promotes Glucose Uptake and Lipid Oxidation in Skeletal Muscle via AMPK Activation
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Journal Articles

Effects of AMPK Activation on Insulin Sensitivity and Metabolism in Leptin-Deficient ob/ob Mice

Robby Zachariah Tom, Pablo M. Garcia-Roves, Rasmus J.O. Sjögren, Lake Q. Jiang, Maria H. Holmström, Atul S. Deshmukh, Elaine Vieira, Alexander V. Chibalin, Marie Björnholm, Juleen R. Zierath
Journal: Diabetes
Diabetes 2014;63(5):1560–1571
https://doi.org/10.2337/db13-0670
Published: 12 April 2014
View article titled, Effects of AMPK Activation on Insulin Sensitivity and Metabolism in Leptin-Deficient <em>ob/ob</em> Mice
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Includes: Supplementary data
Journal Articles

Altered Response of Skeletal Muscle to IL-6 in Type 2 Diabetic Patients

Lake Q. Jiang, Daniella E. Duque-Guimaraes, Ubiratan F. Machado, Juleen R. Zierath, Anna Krook
Journal: Diabetes
Diabetes 2013;62(2):355–361
https://doi.org/10.2337/db11-1790
Published: 17 January 2013
View article titled, Altered Response of Skeletal Muscle to IL-6 in Type 2 Diabetic Patients
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Journal Articles

Constitutive STAT3 Phosphorylation Contributes to Skeletal Muscle Insulin Resistance in Type 2 Diabetes

Fredirick Mashili, Alexander V. Chibalin, Anna Krook, Juleen R. Zierath
Journal: Diabetes
Diabetes 2013;62(2):457–465
https://doi.org/10.2337/db12-0337
Published: 17 January 2013
View article titled, Constitutive STAT3 Phosphorylation Contributes to Skeletal Muscle Insulin Resistance in Type 2 Diabetes
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Journal Articles

Kinetics of GLUT4 Trafficking in Rat and Human Skeletal Muscle

Håkan K.R. Karlsson, Alexander V. Chibalin, Heikki A. Koistinen, Jing Yang, Francoise Koumanov, Harriet Wallberg-Henriksson, Juleen R. Zierath, Geoffrey D. Holman
Journal: Diabetes
Diabetes 2009;58(4):847–854
https://doi.org/10.2337/db08-1539
Published: 02 February 2009
View article titled, Kinetics of GLUT4 Trafficking in Rat and Human Skeletal Muscle
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Journal Articles

siRNA-Mediated Reduction of Inhibitor of Nuclear Factor-κB Kinase Prevents Tumor Necrosis Factor-α–Induced Insulin Resistance in Human Skeletal Muscle

Reginald L. Austin, Anna Rune, Karim Bouzakri, Juleen R. Zierath, Anna Krook
Journal: Diabetes
Diabetes 2008;57(8):2066–2073
https://doi.org/10.2337/db07-0763
Published: 01 August 2008
View article titled, siRNA-Mediated Reduction of Inhibitor of Nuclear Factor-κB Kinase Prevents Tumor Necrosis Factor-α–Induced Insulin Resistance in Human Skeletal Muscle
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Journal Articles

Malonyl CoenzymeA Decarboxylase Regulates Lipid and Glucose Metabolism in Human Skeletal Muscle

Karim Bouzakri, Reginald Austin, Anna Rune, Michael E. Lassman, Pablo M. Garcia-Roves, Joel P. Berger, Anna Krook, Alexander V. Chibalin, Bei B. Zhang, Juleen R. Zierath
Journal: Diabetes
Diabetes 2008;57(6):1508–1516
https://doi.org/10.2337/db07-0583
Published: 01 June 2008
View article titled, Malonyl CoenzymeA Decarboxylase Regulates Lipid and Glucose Metabolism in Human Skeletal Muscle
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Includes: Supplementary data
Journal Articles

Interleukin-6 Directly Increases Glucose Metabolism in Resting Human Skeletal Muscle

Stephan Glund, Atul Deshmukh, Yun Chau Long, Theodore Moller, Heikki A. Koistinen, Kenneth Caidahl, Juleen R. Zierath, Anna Krook
Journal: Diabetes
Diabetes 2007;56(6):1630–1637
https://doi.org/10.2337/db06-1733
Published: 01 June 2007
View article titled, Interleukin-6 Directly Increases Glucose Metabolism in Resting Human Skeletal Muscle
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Journal Articles

AMPK-Mediated AS160 Phosphorylation in Skeletal Muscle Is Dependent on AMPK Catalytic and Regulatory Subunits

Jonas T. Treebak, Stephan Glund, Atul Deshmukh, Ditte K. Klein, Yun Chau Long, Thomas E. Jensen, Sebastian B. Jørgensen, Benoit Viollet, Leif Andersson, Dietbert Neumann, Theo Wallimann, Erik A. Richter, Alexander V. Chibalin, Juleen R. Zierath, Jørgen F.P. Wojtaszewski
Journal: Diabetes
Diabetes 2006;55(7):2051–2058
https://doi.org/10.2337/db06-0175
Published: 01 July 2006
View article titled, AMPK-Mediated AS160 Phosphorylation in Skeletal Muscle Is Dependent on AMPK Catalytic and Regulatory Subunits
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Journal Articles

Exercise-Induced Phosphorylation of the Novel Akt Substrates AS160 and Filamin A in Human Skeletal Muscle

Atul Deshmukh, Vernon G. Coffey, Zhihui Zhong, Alexander V. Chibalin, John A. Hawley, Juleen R. Zierath
Journal: Diabetes
Diabetes 2006;55(6):1776–1782
https://doi.org/10.2337/db05-1419
Published: 01 June 2006
View article titled, Exercise-Induced Phosphorylation of the Novel Akt Substrates AS160 and Filamin A in Human Skeletal Muscle
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