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Juris J. Meier
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Journal Articles

Effects of metformin on postprandial blood pressure, heart rate, gastric emptying, GLP-1 and the prevalence of postprandial hypotension in type 2 diabetes – a double-blind, placebo-controlled crossover study

Daniel R. Quast, MD, Cong Xie, PhD, Michelle J. Bound, BMedRad, Jacqueline Grivell, DipAppSc, Seva Hatzinikolas, DipAppSc, Karen L. Jones, PhD, Michael Horowitz, DSc, Christopher K. Rayner, PhD, Michael A. Nauck, MD, Juris J. Meier, MD, Liza K. Phillips, PhD, Tongzhi Wu, PhD
Journal: Diabetes
Diabetes db240830
https://doi.org/10.2337/db24-0830
Published: 06 January 2025
View article titled, Effects of metformin on postprandial blood pressure, heart rate, gastric emptying, GLP-1 and the prevalence of postprandial hypotension in type 2 diabetes – a double-blind, placebo-controlled crossover study
Open the PDF for Effects of metformin on postprandial blood pressure, heart rate, gastric emptying, GLP-1 and the prevalence of postprandial hypotension in type 2 diabetes – a double-blind, placebo-controlled crossover study in another window
Meeting Abstracts

668-P: Body Weight Loss with Oral Semaglutide Is Predominantly Mediated by Effects Other than Gastrointestinal Adverse Events

JURIS J. MEIER, RIKKE AGESEN, LARS BARDTRUM, ALICE Y. CHENG, SRIKANTH DEENADAYALAN, EDUARD MONTANYA, RICHARD E. PRATLEY
Journal: Diabetes
Diabetes 2021;70(Supplement_1):668-P
https://doi.org/10.2337/db21-668-P
Published: 01 June 2021
View article titled, 668-P: Body Weight Loss with Oral Semaglutide Is Predominantly Mediated by Effects Other than Gastrointestinal Adverse Events
Meeting Abstracts

342-P: Effects of Sitagliptin on Hypoglycemic Episodes and Counterregulation in Type 2 Diabetic Patients Tightly Titrated with Insulin Glargine

MICHAEL A. NAUCK, ANDRE FELDMANN, JURIS J. MEIER, MATTHIAS NAUCK, CHRISTOPH KAPITZA
Journal: Diabetes
Diabetes 2021;70(Supplement_1):342-P
https://doi.org/10.2337/db21-342-P
Published: 01 June 2021
View article titled, 342-P: Effects of Sitagliptin on Hypoglycemic Episodes and Counterregulation in Type 2 Diabetic Patients Tightly Titrated with Insulin Glargine
Meeting Abstracts

927-P: Effect of Oral Semaglutide with or without Background SGLT2i in Patients with T2D: Subgroup Analysis of PIONEER 4

RICHARD E. PRATLEY, ROBERT BAUER, SILVIO E. INZUCCHI, KAMLESH KHUNTI, ESKIL B. KREINER, PETER N. LAURSEN, JURIS J. MEIER
Journal: Diabetes
Diabetes 2020;69(Supplement_1):927-P
https://doi.org/10.2337/db20-927-P
Published: 01 June 2020
View article titled, 927-P: Effect of Oral Semaglutide with or without Background SGLT2i in Patients with T2D: Subgroup Analysis of PIONEER 4
Meeting Abstracts

88-LB: Similar Efficacy and Safety of IGlarLixi When Initiated in Patients with Type 2 Diabetes (T2D) with or without Concomitant Sodium-Glucose Cotransporter-2 Inhibitor (SGLT2i) Use in a Randomized Controlled Trial (RCT) and Real-World Setting

JULIO ROSENSTOCK, AMAR ALI, JURIS J. MEIER, FRANCESCO GIORGINO, CRISTIAN GUJA, MARTIN PRAZNY, ROBERT LUBWAMA, ELISABETH SOUHAMI, LAWRENCE BLONDE
Journal: Diabetes
Diabetes 2020;69(Supplement_1):88-LB
https://doi.org/10.2337/db20-88-LB
Published: 01 June 2020
View article titled, 88-LB: Similar Efficacy and Safety of IGlarLixi When Initiated in Patients with Type 2 Diabetes (T2D) with or without Concomitant Sodium-Glucose Cotransporter-2 Inhibitor (SGLT2i) Use in a Randomized Controlled Trial (RCT) and Real-World Setting
Meeting Abstracts

1010-P: Effects of MEDI0382, an Oxyntomodulin-Like Peptide with Targeted GLP-1/Glucagon Receptor Activity, on Amino Acids, Ketones, and Free Fatty Acids

VICTORIA E. PARKER, DARREN ROBERTSON, TAO WANG, DAVID C. HORNIGOLD, MAXIMILIAN G. POSCH, LEONA PLUM-MOERSCHEL, JURIS J. MEIER, HEIKE SCHLICHTHAAR, BEATE M. KLAUS, LUTZ JERMUTUS, PHILIP AMBERY, BOAZ HIRSHBERG
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1010-P
https://doi.org/10.2337/db19-1010-P
Published: 01 June 2019
View article titled, 1010-P: Effects of MEDI0382, an Oxyntomodulin-Like Peptide with Targeted GLP-1/Glucagon Receptor Activity, on Amino Acids, Ketones, and Free Fatty Acids
Meeting Abstracts

1013-P: Effect of Upper Gastrointestinal Disease on the Pharmacokinetics of Oral Semaglutide in Subjects with Type 2 Diabetes

JURIS J. MEIER, CHARLOTTE GRANHALL, ULRIKE HOEVELMANN, ANDREA NAVARRIA, SR., LEONA PLUM-MOERSCHEL, CHETHANA RAMESH, ANDREA TANNAPFEL, CHRISTOPH KAPITZA
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1013-P
https://doi.org/10.2337/db19-1013-P
Published: 01 June 2019
View article titled, 1013-P: Effect of Upper Gastrointestinal Disease on the Pharmacokinetics of Oral Semaglutide in Subjects with Type 2 Diabetes
Meeting Abstracts

1017-P: Continuous Glucose Monitoring Reveals Comprehensive Glucose Control with MEDI0382, an Oxyntomodulin-Like Peptide with Targeted GLP-1/Glucagon Receptor Activity

VICTORIA E.R. PARKER, DARREN ROBERTSON, TAO WANG, DAVID C. HORNIGOLD, MAXIMILIAN G. POSCH, TIM HEISE, LEONA PLUM-MOERSCHEL, JURIS J. MEIER, HEIKE SCHLICHTHAAR, BEATE M. KLAUS, PHILIP AMBERY, BOAZ HIRSHBERG
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1017-P
https://doi.org/10.2337/db19-1017-P
Published: 01 June 2019
View article titled, 1017-P: Continuous Glucose Monitoring Reveals Comprehensive Glucose Control with MEDI0382, an Oxyntomodulin-Like Peptide with Targeted GLP-1/Glucagon Receptor Activity
Meeting Abstracts

988-P: MEDI0382, an Oxyntomodulin-Like Peptide with Targeted GLP-1/Glucagon Receptor Activity, Promotes a Dose-Dependent Increase in Gastric Emptying Time

DARREN ROBERTSON, VICTORIA E. PARKER, PHILIP AMBERY, MARCELLA PETRONE, TAO WANG, TIM HEISE, LEONA PLUM-MOERSCHEL, LUTZ JERMUTUS, BOAZ HIRSHBERG, JURIS J. MEIER
Journal: Diabetes
Diabetes 2019;68(Supplement_1):988-P
https://doi.org/10.2337/db19-988-P
Published: 01 June 2019
View article titled, 988-P: MEDI0382, an Oxyntomodulin-Like Peptide with Targeted GLP-1/Glucagon Receptor Activity, Promotes a Dose-Dependent Increase in Gastric Emptying Time
Meeting Abstracts

55-OR: Oral Semaglutide vs. Liraglutide and Placebo in T2D: PIONEER 4

RICHARD E. PRATLEY, ASLAM AMOD, SOREN T. HOFF, TAKASHI KADOWAKI, ILDIKO LINGVAY, MICHAEL A. NAUCK, KAREN BOJE PEDERSEN, TRINE SAUGSTRUP, JURIS J. MEIER, FOR THE PIONEER 4 INVESTIGATORS
Journal: Diabetes
Diabetes 2019;68(Supplement_1):55-OR
https://doi.org/10.2337/db19-55-OR
Published: 01 June 2019
View article titled, 55-OR: Oral Semaglutide vs. Liraglutide and Placebo in T2D: PIONEER 4
Journal Articles

GIP and GLP-1: Stepsiblings Rather Than Monozygotic Twins Within the Incretin Family

Michael A. Nauck, Juris J. Meier
Journal: Diabetes
Diabetes 2019;68(5):897–900
https://doi.org/10.2337/dbi19-0005
Published: 16 April 2019
View article titled, GIP and GLP-1: Stepsiblings Rather Than Monozygotic Twins Within the Incretin Family
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Meeting Abstracts

More Subjects Achieved Composite Reductions of =1% HbA1c, =5% Body Weight, and =5 mmHg SBP with Semaglutide vs. Comparators (SUSTAIN 1-5, 7)

KATHLEEN M. DUNGAN, VANITA ARODA, FILIP K. KNOP, LAWRENCE A. LEITER, NANNA L. LAUSVIG, SØREN LINDBERG, JURIS J. MEIER
Journal: Diabetes
Diabetes 2018;67(Supplement_1):129-OR
https://doi.org/10.2337/db18-129-OR
Published: 01 July 2018
View article titled, More Subjects Achieved Composite Reductions of =1% HbA1c, =5% Body Weight, and =5 mmHg SBP with Semaglutide vs. Comparators (SUSTAIN 1-5, 7)
Journal Articles

Loss of Inverse Relationship Between Pulsatile Insulin and Glucagon Secretion in Patients With Type 2 Diabetes

Björn A. Menge, Lena Grüber, Signe M. Jørgensen, Carolyn F. Deacon, Wolfgang E. Schmidt, Johannes D. Veldhuis, Jens J. Holst, Juris J. Meier
Journal: Diabetes
Diabetes 2011;60(8):2160–2168
https://doi.org/10.2337/db11-0251
Published: 18 July 2011
View article titled, Loss of Inverse Relationship Between Pulsatile Insulin and Glucagon Secretion in Patients With Type 2 Diabetes
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Journal Articles

Rapid Tachyphylaxis of the Glucagon-Like Peptide 1–Induced Deceleration of Gastric Emptying in Humans

Michael A. Nauck, Guido Kemmeries, Jens J. Holst, Juris J. Meier
Journal: Diabetes
Diabetes 2011;60(5):1561–1565
https://doi.org/10.2337/db10-0474
Published: 23 April 2011
View article titled, Rapid Tachyphylaxis of the Glucagon-Like Peptide 1–Induced Deceleration of Gastric Emptying in Humans
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Includes: Supplementary data
Journal Articles

GIP Does Not Potentiate the Antidiabetic Effects of GLP-1 in Hyperglycemic Patients With Type 2 Diabetes

Nikolaos Mentis, Irfan Vardarli, Lars D. Köthe, Jens J. Holst, Carolyn F. Deacon, Michael Theodorakis, Juris J. Meier, Michael A. Nauck
Journal: Diabetes
Diabetes 2011;60(4):1270–1276
https://doi.org/10.2337/db10-1332
Published: 22 March 2011
View article titled, GIP Does Not Potentiate the Antidiabetic Effects of GLP-1 in Hyperglycemic Patients With Type 2 Diabetes
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Journal Articles

Is the Diminished Incretin Effect in Type 2 Diabetes Just an Epi-Phenomenon of Impaired β-Cell Function?

Juris J. Meier, Michael A. Nauck
Journal: Diabetes
Diabetes 2010;59(5):1117–1125
https://doi.org/10.2337/db09-1899
Published: 01 May 2010
View article titled, Is the Diminished Incretin Effect in Type 2 Diabetes Just an Epi-Phenomenon of Impaired β-Cell Function?
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Journal Articles

Generation of Novel Single-Chain Antibodies by Phage-Display Technology to Direct Imaging Agents Highly Selective to Pancreatic β- or α-Cells In Vivo

Sandra Ueberberg, Juris J. Meier, Carmen Waengler, Wolfgang Schechinger, Johannes W. Dietrich, Andrea Tannapfel, Inge Schmitz, Ralf Schirrmacher, Manfred Köller, Harald H. Klein, Stephan Schneider
Journal: Diabetes
Diabetes 2009;58(10):2324–2334
https://doi.org/10.2337/db09-0658
Published: 10 July 2009
View article titled, Generation of Novel Single-Chain Antibodies by Phage-Display Technology to Direct Imaging Agents Highly Selective to Pancreatic β- or α-Cells In Vivo
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Journal Articles

Functional Assessment of Pancreatic β-Cell Area in Humans

Juris J. Meier, Bjoern A. Menge, Thomas G.K. Breuer, Christophe A. Müller, Andrea Tannapfel, Waldemar Uhl, Wolfgang E. Schmidt, Henning Schrader
Journal: Diabetes
Diabetes 2009;58(7):1595–1603
https://doi.org/10.2337/db08-1611
Published: 01 July 2009
View article titled, Functional Assessment of Pancreatic β-Cell Area in Humans
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Journal Articles

Linking the Genetics of Type 2 Diabetes With Low Birth Weight: A Role for Prenatal Islet Maldevelopment?

Juris J. Meier
Journal: Diabetes
Diabetes 2009;58(6):1255–1256
https://doi.org/10.2337/db09-0225
Published: 01 June 2009
View article titled, Linking the Genetics of Type 2 Diabetes With Low Birth Weight: <subtitle>A Role for Prenatal Islet Maldevelopment?</subtitle>
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Journal Articles

β-Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of β-Cell Mass in Humans

Juris J. Meier, Alexandra E. Butler, Yoshifumi Saisho, Travis Monchamp, Ryan Galasso, Anil Bhushan, Robert A. Rizza, Peter C. Butler
Journal: Diabetes
Diabetes 2008;57(6):1584–1594
https://doi.org/10.2337/db07-1369
Published: 01 June 2008
View article titled, β-Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of β-Cell Mass in Humans
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