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Jussi Paananen
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Journal Articles

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

Andrew R. Wood, Anna Jonsson, Anne U. Jackson, Nan Wang, Nienke van Leewen, Nicholette D. Palmer, Sayuko Kobes, Joris Deelen, Lorena Boquete-Vilarino, Jussi Paananen, Alena Stančáková, Dorret I. Boomsma, Eco J.C. de Geus, Elisabeth M.W. Eekhoff, Andreas Fritsche, Mark Kramer, Giel Nijpels, Annemarie Simonis-Bik, Timon W. van Haeften, Anubha Mahajan, Michael Boehnke, Richard N. Bergman, Jaakko Tuomilehto, Francis S. Collins, Karen L. Mohlke, Karina Banasik, Christopher J. Groves, Mark I. McCarthy, Diabetes Research on Patient Stratification (DIRECT), Ewan R. Pearson, Andrea Natali, Andrea Mari, Thomas A. Buchanan, Kent D. Taylor, Anny H. Xiang, Anette P. Gjesing, Niels Grarup, Hans Eiberg, Oluf Pedersen, Yii-Derr Chen, Markku Laakso, Jill M. Norris, Ulf Smith, Lynne E. Wagenknecht, Leslie Baier, Donald W. Bowden, Torben Hansen, Mark Walker, Richard M. Watanabe, Leen M. ‘t Hart, Robert L. Hanson, Timothy M. Frayling
Journal: Diabetes
Diabetes 2017;66(8):2296–2309
https://doi.org/10.2337/db16-1452
Published: 10 May 2017
View article titled, A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants
Open the PDF for A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants in another window
Includes: Supplementary data
Journal Articles

Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes

Hanieh Yaghootkar, Claudia Lamina, Robert A. Scott, Zari Dastani, Marie-France Hivert, Liling L. Warren, Alena Stancáková, Sarah G. Buxbaum, Leo-Pekka Lyytikäinen, Peter Henneman, Ying Wu, Chloe Y.Y. Cheung, James S. Pankow, Anne U. Jackson, Stefan Gustafsson, Jing Hua Zhao, Christie M. Ballantyne, Weijia Xie, Richard N. Bergman, Michael Boehnke, Fatiha el Bouazzaoui, Francis S. Collins, Sandra H. Dunn, Josee Dupuis, Nita G. Forouhi, Christopher Gillson, Andrew T. Hattersley, Jaeyoung Hong, Mika Kähönen, Johanna Kuusisto, Lyudmyla Kedenko, Florian Kronenberg, Alessandro Doria, Themistocles L. Assimes, Ele Ferrannini, Torben Hansen, Ke Hao, Hans Häring, Joshua W. Knowles, Cecilia M. Lindgren, John J. Nolan, Jussi Paananen, Oluf Pedersen, Thomas Quertermous, Ulf Smith, the GENESIS Consortium, the RISC Consortium, Terho Lehtimäki, Ching-Ti Liu, Ruth J.F. Loos, Mark I. McCarthy, Andrew D. Morris, Ramachandran S. Vasan, Tim D. Spector, Tanya M. Teslovich, Jaakko Tuomilehto, Ko Willems van Dijk, Jorma S. Viikari, Na Zhu, Claudia Langenberg, Erik Ingelsson, Robert K. Semple, Alan R. Sinaiko, Colin N.A. Palmer, Mark Walker, Karen S.L. Lam, Bernhard Paulweber, Karen L. Mohlke, Cornelia van Duijn, Olli T. Raitakari, Aurelian Bidulescu, Nick J. Wareham, Markku Laakso, Dawn M. Waterworth, Debbie A. Lawlor, James B. Meigs, J. Brent Richards, Timothy M. Frayling
Journal: Diabetes
Diabetes 2013;62(10):3589–3598
https://doi.org/10.2337/db13-0128
Published: 17 September 2013
View article titled, Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes
Open the PDF for Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes in another window
Includes: Supplementary data
Journal Articles

Association of Ketone Body Levels With Hyperglycemia and Type 2 Diabetes in 9,398 Finnish Men

Yuvaraj Mahendran, Jagadish Vangipurapu, Henna Cederberg, Alena Stančáková, Jussi Pihlajamäki, Pasi Soininen, Antti J. Kangas, Jussi Paananen, Mete Civelek, Niyas K. Saleem, Päivi Pajukanta, Aldons J. Lusis, Lori L. Bonnycastle, Mario A. Morken, Francis S. Collins, Karen L. Mohlke, Michael Boehnke, Mika Ala-Korpela, Johanna Kuusisto, Markku Laakso
Journal: Diabetes
Diabetes 2013;62(10):3618–3626
https://doi.org/10.2337/db12-1363
Published: 17 September 2013
View article titled, Association of Ketone Body Levels With Hyperglycemia and Type 2 Diabetes in 9,398 Finnish Men
Open the PDF for Association of Ketone Body Levels With Hyperglycemia and Type 2 Diabetes in 9,398 Finnish Men in another window
Includes: Supplementary data
Journal Articles

Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes

Weijia Xie, Andrew R. Wood, Valeriya Lyssenko, Michael N. Weedon, Joshua W. Knowles, Sami Alkayyali, Themistocles L. Assimes, Thomas Quertermous, Fahim Abbasi, Jussi Paananen, Hans Häring, Torben Hansen, Oluf Pedersen, Ulf Smith, Markku Laakso, the MAGIC Investigators, the DIAGRAM Consortium, the GENESIS Consortium, the RISC Consortium, Jacqueline M. Dekker, John J. Nolan, Leif Groop, Ele Ferrannini, Klaus-Peter Adam, Walter E. Gall, Timothy M. Frayling, Mark Walker
Journal: Diabetes
Diabetes 2013;62(6):2141–2150
https://doi.org/10.2337/db12-0876
Published: 17 May 2013
View article titled, Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes
Open the PDF for Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes in another window
Includes: Supplementary data
Journal Articles

Hyperglycemia and a Common Variant of GCKR Are Associated With the Levels of Eight Amino Acids in 9,369 Finnish Men

Alena Stančáková, Mete Civelek, Niyas K. Saleem, Pasi Soininen, Antti J. Kangas, Henna Cederberg, Jussi Paananen, Jussi Pihlajamäki, Lori L. Bonnycastle, Mario A. Morken, Michael Boehnke, Päivi Pajukanta, Aldons J. Lusis, Francis S. Collins, Johanna Kuusisto, Mika Ala-Korpela, Markku Laakso
Journal: Diabetes
Diabetes 2012;61(7):1895–1902
https://doi.org/10.2337/db11-1378
Published: 15 June 2012
View article titled, Hyperglycemia and a Common Variant of <em>GCKR</em> Are Associated With the Levels of Eight Amino Acids in 9,369 Finnish Men
Open the PDF for Hyperglycemia and a Common Variant of <em>GCKR</em> Are Associated With the Levels of Eight Amino Acids in 9,369 Finnish Men in another window
Includes: Supplementary data
Journal Articles

Effects of 34 Risk Loci for Type 2 Diabetes or Hyperglycemia on Lipoprotein Subclasses and Their Composition in 6,580 Nondiabetic Finnish Men

Alena Stančáková, Jussi Paananen, Pasi Soininen, Antti J. Kangas, Lori L. Bonnycastle, Mario A. Morken, Francis S. Collins, Anne U. Jackson, Michael L. Boehnke, Johanna Kuusisto, Mika Ala-Korpela, Markku Laakso
Journal: Diabetes
Diabetes 2011;60(5):1608–1616
https://doi.org/10.2337/db10-1655
Published: 23 April 2011
View article titled, Effects of 34 Risk Loci for Type 2 Diabetes or Hyperglycemia on Lipoprotein Subclasses and Their Composition in 6,580 Nondiabetic Finnish Men
Open the PDF for Effects of 34 Risk Loci for Type 2 Diabetes or Hyperglycemia on Lipoprotein Subclasses and Their Composition in 6,580 Nondiabetic Finnish Men in another window
Includes: Supplementary data
Journal Articles

Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men

Alena Stančáková, Teemu Kuulasmaa, Jussi Paananen, Anne U. Jackson, Lori L. Bonnycastle, Francis S. Collins, Michael Boehnke, Johanna Kuusisto, Markku Laakso
Journal: Diabetes
Diabetes 2009;58(9):2129–2136
https://doi.org/10.2337/db09-0117
Published: 05 June 2009
View article titled, Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men
Open the PDF for Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men in another window
Includes: Supplementary data