Page 1 | Search Results | Diabetes | American Diabetes Association

1-17 of 17

Sort by

Sort Order Select

Journal Articles

Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells

Hainan Chen, Jeffrey W. Kleinberger, Karen K. Takane, Fatimah Salim, Nathalie Fiaschi-Taesch, Kyrie Pappas, Ramon Parsons, Jing Jiang, Yue Zhang, Hongtao Liu, Peng Wang, Aaron S. Bender, Stuart J. Frank, Andrew F. Stewart

Diabetes 2015;64(11):3784–3797

https://doi.org/10.2337/db15-0083

Published: 09 July 2015

View article titled, Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells

Includes: Supplementary data

Journal Articles

Early and Late G1/S Cyclins and Cdks Act Complementarily to Enhance Authentic Human β-Cell Proliferation and Expansion

Shiwani Tiwari, Chris Roel, Rachel Wills, Gabriella Casinelli, Mansoor Tanwir, Karen K. Takane, Nathalie M. Fiaschi-Taesch

Diabetes 2015;64(10):3485–3498

https://doi.org/10.2337/db14-1885

Published: 09 July 2015

View article titled, Early and Late G1/S Cyclins and Cdks Act Complementarily to Enhance Authentic Human β-Cell Proliferation and Expansion

Includes: Supplementary data

Journal Articles

Human Pancreatic β-Cell G1/S Molecule Cell Cycle Atlas

Nathalie M. Fiaschi-Taesch, Jeffrey W. Kleinberger, Fatimah G. Salim, Ronnie Troxell, Rachel Wills, Mansoor Tanwir, Gabriella Casinelli, Amy E. Cox, Karen K. Takane, Donald K. Scott, Andrew F. Stewart

Diabetes 2013;62(7):2450–2459

https://doi.org/10.2337/db12-0777

Published: 14 June 2013

View article titled, Human Pancreatic β-Cell G1/S Molecule Cell Cycle Atlas

Includes: Supplementary data

Journal Articles

Cytoplasmic-Nuclear Trafficking of G1/S Cell Cycle Molecules and Adult Human β-Cell Replication: A Revised Model of Human β-Cell G1/S Control

Nathalie M. Fiaschi-Taesch, Jeffrey W. Kleinberger, Fatimah G. Salim, Ronnie Troxell, Rachel Wills, Mansoor Tanwir, Gabriella Casinelli, Amy E. Cox, Karen K. Takane, Harish Srinivas, Donald K. Scott, Andrew F. Stewart

Diabetes 2013;62(7):2460–2470

https://doi.org/10.2337/db12-0778

Published: 14 June 2013

View article titled, Cytoplasmic-Nuclear Trafficking of G1/S Cell Cycle Molecules and Adult Human β-Cell Replication: <subtitle>A Revised Model of Human β-Cell G1/S Control</subtitle>

Includes: Multimedia, Supplementary data

Journal Articles

ChREBP Mediates Glucose-Stimulated Pancreatic β-Cell Proliferation

Mallikarjuna R. Metukuri, Pili Zhang, Mahesh K. Basantani, Connie Chin, Rachel E. Stamateris, Laura C. Alonso, Karen K. Takane, Roberto Gramignoli, Stephen C. Strom, Robert M. O’Doherty, Andrew F. Stewart, Rupangi C. Vasavada, Adolfo Garcia-Ocaña, Donald K. Scott

Diabetes 2012;61(8):2004–2015

https://doi.org/10.2337/db11-0802

Published: 17 July 2012

View article titled, ChREBP Mediates Glucose-Stimulated Pancreatic β-Cell Proliferation

Includes: Supplementary data

Journal Articles

Regulated and Reversible Induction of Adult Human β-Cell Replication

Karen K. Takane, Jeffery W. Kleinberger, Fatimah G. Salim, Nathalie M. Fiaschi-Taesch, Andrew F. Stewart

Diabetes 2012;61(2):418–424

https://doi.org/10.2337/db11-0580

Published: 17 January 2012

View article titled, Regulated and Reversible Induction of Adult Human β-Cell Replication

Includes: Supplementary data

Journal Articles

Activation of Protein Kinase C-ζ in Pancreatic β-Cells In Vivo Improves Glucose Tolerance and Induces β-Cell Expansion via mTOR Activation

Silvia Velazquez-Garcia, Shelley Valle, Taylor C. Rosa, Karen K. Takane, Cem Demirci, Juan C. Alvarez-Perez, Jose M. Mellado-Gil, Sara Ernst, Donald K. Scott, Rupangi C. Vasavada, Laura C. Alonso, Adolfo Garcia-Ocaña

Diabetes 2011;60(10):2546–2559

https://doi.org/10.2337/db10-1783

Published: 16 September 2011

View article titled, Activation of Protein Kinase C-ζ in Pancreatic β-Cells In Vivo Improves Glucose Tolerance and Induces β-Cell Expansion via mTOR Activation

Includes: Supplementary data

Journal Articles

Parathyroid Hormone–Related Protein Enhances Human β-Cell Proliferation and Function With Associated Induction of Cyclin-Dependent Kinase 2 and Cyclin E Expression

Nagesha Guthalu Kondegowda, Sheela Joshi-Gokhale, George Harb, Katoura Williams, Xiao Ying Zhang, Karen K. Takane, Pili Zhang, Donald K. Scott, Andrew F. Stewart, Adolfo Garcia-Ocaña, Rupangi C. Vasavada

Diabetes 2010;59(12):3131–3138

https://doi.org/10.2337/db09-1796

Published: 28 September 2010

View article titled, Parathyroid Hormone–Related Protein Enhances Human β-Cell Proliferation and Function With Associated Induction of Cyclin-Dependent Kinase 2 and Cyclin E Expression

Includes: Supplementary data

Journal Articles

Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6

Nathalie M. Fiaschi-Taesch, Fatimah Salim, Jeffrey Kleinberger, Ronnie Troxell, Irene Cozar-Castellano, Karen Selk, Edward Cherok, Karen K. Takane, Donald K. Scott, Andrew F. Stewart

Diabetes 2010;59(8):1926–1936

https://doi.org/10.2337/db09-1776

Published: 01 August 2010

View article titled, Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6

Includes: Supplementary data

Journal Articles

Plasma Membrane Subdomain Compartmentalization Contributes to Distinct Mechanisms of Ceramide Action on Insulin Signaling

Cédric M. Blouin, Cécilia Prado, Karen K. Takane, Françoise Lasnier, Adolfo Garcia-Ocana, Pascal Ferré, Isabelle Dugail, Eric Hajduch

Diabetes 2010;59(3):600–610

https://doi.org/10.2337/db09-0897

Published: 03 December 2009

View article titled, Plasma Membrane Subdomain Compartmentalization Contributes to Distinct Mechanisms of Ceramide Action on Insulin Signaling

Journal Articles

Survey of the Human Pancreatic β-Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D₁ in Enhancing Human β-Cell Replication and Function In Vivo

Nathalie Fiaschi-Taesch, Todd A. Bigatel, Brian Sicari, Karen K. Takane, Fatima Salim, Silvia Velazquez-Garcia, George Harb, Karen Selk, Irene Cozar-Castellano, Andrew F. Stewart

Diabetes 2009;58(4):882–893

https://doi.org/10.2337/db08-0631

Published: 09 January 2009

View article titled, Survey of the Human Pancreatic β-Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D<sub>1</sub> in Enhancing Human β-Cell Replication and Function In Vivo

Includes: Supplementary data

Journal Articles

Hepatocyte Growth Factor Enhances Engraftment and Function of Nonhuman Primate Islets

Nathalie M. Fiaschi-Taesch, Dora M. Berman, Brian M. Sicari, Karen K. Takane, Adolfo Garcia-Ocaña, Camillo Ricordi, Norma S. Kenyon, Andrew F. Stewart

Diabetes 2008;57(10):2745–2754

https://doi.org/10.2337/db07-1085

Published: 01 October 2008

View article titled, Hepatocyte Growth Factor Enhances Engraftment and Function of Nonhuman Primate Islets

Journal Articles

Protein Kinase C-ζ Activation Markedly Enhances β-Cell Proliferation: An Essential Role in Growth Factor–Mediated β-Cell Mitogenesis

Rupangi C. Vasavada, Lin Wang, Yuichi Fujinaka, Karen K. Takane, Taylor C. Rosa, Jose M.D. Mellado-Gil, Peter A. Friedman, Adolfo Garcia-Ocaña

Diabetes 2007;56(11):2732–2743

https://doi.org/10.2337/db07-0461

Published: 01 November 2007

View article titled, Protein Kinase C-ζ Activation Markedly Enhances β-Cell Proliferation: <subtitle>An Essential Role in Growth Factor–Mediated β-Cell Mitogenesis</subtitle>

Includes: Supplementary data

Journal Articles

Gene Transfer of Constitutively Active Akt Markedly Improves Human Islet Transplant Outcomes in Diabetic Severe Combined Immunodeficient Mice

Poornima Rao, Jennifer Roccisana, Karen K. Takane, Rita Bottino, Allan Zhao, Massimo Trucco, Adolfo García-Ocaña

Diabetes 2005;54(6):1664–1675

https://doi.org/10.2337/diabetes.54.6.1664

Published: 01 June 2005

View article titled, Gene Transfer of Constitutively Active Akt Markedly Improves Human Islet Transplant Outcomes in Diabetic Severe Combined Immunodeficient Mice

Journal Articles

Induction of β-Cell Proliferation and Retinoblastoma Protein Phosphorylation in Rat and Human Islets Using Adenovirus-Mediated Transfer of Cyclin-Dependent Kinase-4 and Cyclin D₁

Irene Cozar-Castellano, Karen K. Takane, Rita Bottino, A.N. Balamurugan, Andrew F. Stewart

Diabetes 2004;53(1):149–159

https://doi.org/10.2337/diabetes.53.1.149

Published: 01 January 2004

View article titled, Induction of β-Cell Proliferation and Retinoblastoma Protein Phosphorylation in Rat and Human Islets Using Adenovirus-Mediated Transfer of Cyclin-Dependent Kinase-4 and Cyclin D<sub>1</sub>

Journal Articles

Overexpression of Parathyroid Hormone-Related Protein Inhibits Pancreatic β-Cell Death In Vivo and In Vitro

Ana Cebrian, Adolfo García-Ocaña, Karen K. Takane, Darinka Sipula, Andrew F. Stewart, Rupangi C. Vasavada

Diabetes 2002;51(10):3003–3013

https://doi.org/10.2337/diabetes.51.10.3003

Published: 01 October 2002

View article titled, Overexpression of Parathyroid Hormone-Related Protein Inhibits Pancreatic β-Cell Death In Vivo and In Vitro

Journal Articles

Transgenic Overexpression of Hepatocyte Growth Factor in the β-Cell Markedly Improves Islet Function and Islet Transplant Outcomes in Mice

Adolfo García-Ocaña, Rupangi C. Vasavada, Ana Cebrian, Vasumathi Reddy, Karen K. Takane, Juan-Carlos López-Talavera, Andrew F. Stewart

Diabetes 2001;50(12):2752–2762

https://doi.org/10.2337/diabetes.50.12.2752

Published: 01 December 2001

View article titled, Transgenic Overexpression of Hepatocyte Growth Factor in the β-Cell Markedly Improves Islet Function and Islet Transplant Outcomes in Mice

NARROW

Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells

Early and Late G1/S Cyclins and Cdks Act Complementarily to Enhance Authentic Human β-Cell Proliferation and Expansion

Human Pancreatic β-Cell G1/S Molecule Cell Cycle Atlas

Cytoplasmic-Nuclear Trafficking of G1/S Cell Cycle Molecules and Adult Human β-Cell Replication: A Revised Model of Human β-Cell G1/S Control

ChREBP Mediates Glucose-Stimulated Pancreatic β-Cell Proliferation

Regulated and Reversible Induction of Adult Human β-Cell Replication

Activation of Protein Kinase C-ζ in Pancreatic β-Cells In Vivo Improves Glucose Tolerance and Induces β-Cell Expansion via mTOR Activation

Parathyroid Hormone–Related Protein Enhances Human β-Cell Proliferation and Function With Associated Induction of Cyclin-Dependent Kinase 2 and Cyclin E Expression

Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6

Plasma Membrane Subdomain Compartmentalization Contributes to Distinct Mechanisms of Ceramide Action on Insulin Signaling

Survey of the Human Pancreatic β-Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D₁ in Enhancing Human β-Cell Replication and Function In Vivo

Hepatocyte Growth Factor Enhances Engraftment and Function of Nonhuman Primate Islets

Protein Kinase C-ζ Activation Markedly Enhances β-Cell Proliferation: An Essential Role in Growth Factor–Mediated β-Cell Mitogenesis

Gene Transfer of Constitutively Active Akt Markedly Improves Human Islet Transplant Outcomes in Diabetic Severe Combined Immunodeficient Mice

Induction of β-Cell Proliferation and Retinoblastoma Protein Phosphorylation in Rat and Human Islets Using Adenovirus-Mediated Transfer of Cyclin-Dependent Kinase-4 and Cyclin D₁

Overexpression of Parathyroid Hormone-Related Protein Inhibits Pancreatic β-Cell Death In Vivo and In Vitro

Transgenic Overexpression of Hepatocyte Growth Factor in the β-Cell Markedly Improves Islet Function and Islet Transplant Outcomes in Mice

Email alerts

Journals

Books

Clinical Compendia

News

Podcasts

Other

About

Resources

Email alerts

Journals

Books

Clinical Compendia

News

Podcasts

Other

About

Resources

This Feature Is Available To Subscribers Only