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Karen L. Jones
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Journal Articles

Effects of metformin on postprandial blood pressure, heart rate, gastric emptying, GLP-1 and the prevalence of postprandial hypotension in type 2 diabetes – a double-blind, placebo-controlled crossover study

Daniel R. Quast, MD, Cong Xie, PhD, Michelle J. Bound, BMedRad, Jacqueline Grivell, DipAppSc, Seva Hatzinikolas, DipAppSc, Karen L. Jones, PhD, Michael Horowitz, DSc, Christopher K. Rayner, PhD, Michael A. Nauck, MD, Juris J. Meier, MD, Liza K. Phillips, PhD, Tongzhi Wu, PhD
Journal: Diabetes
Diabetes db240830
https://doi.org/10.2337/db24-0830
Published: 06 January 2025
View article titled, Effects of metformin on postprandial blood pressure, heart rate, gastric emptying, GLP-1 and the prevalence of postprandial hypotension in type 2 diabetes – a double-blind, placebo-controlled crossover study
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Journal Articles

Glucose Sensing Mediated by Portal Glucagon-Like Peptide 1 Receptor Is Markedly Impaired in Insulin-Resistant Obese Animals

Charles-Henri Malbert, Alain Chauvin, Michael Horowitz, Karen L. Jones
Journal: Diabetes
Diabetes 2021;70(1):99–110
https://doi.org/10.2337/db20-0361
Published: 16 October 2020
View article titled, Glucose Sensing Mediated by Portal Glucagon-Like Peptide 1 Receptor Is Markedly Impaired in Insulin-Resistant Obese Animals
Open the PDF for Glucose Sensing Mediated by Portal Glucagon-Like Peptide 1 Receptor Is Markedly Impaired in Insulin-Resistant Obese Animals in another window
Journal Articles

DPP-4 Inhibition and the Known Unknown

Michael Horowitz, Tongzhi Wu, Adam M. Deane, Karen L. Jones, Christopher K. Rayner
Journal: Diabetes
Diabetes 2016;65(8):2124–2126
https://doi.org/10.2337/dbi16-0023
Published: 12 July 2016
View article titled, DPP-4 Inhibition and the Known Unknown
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Journal Articles

The Glucagon-Like Peptide 1 Receptor Agonist Exenatide Inhibits Small Intestinal Motility, Flow, Transit, and Absorption of Glucose in Healthy Subjects and Patients With Type 2 Diabetes: A Randomized Controlled Trial

Sony S. Thazhath, Chinmay S. Marathe, Tongzhi Wu, Jessica Chang, Joan Khoo, Paul Kuo, Helen L. Checklin, Michelle J. Bound, Rachael S. Rigda, Benjamin Crouch, Karen L. Jones, Michael Horowitz, Christopher K. Rayner
Journal: Diabetes
Diabetes 2016;65(1):269–275
https://doi.org/10.2337/db15-0893
Published: 15 October 2015
View article titled, The Glucagon-Like Peptide 1 Receptor Agonist Exenatide Inhibits Small Intestinal Motility, Flow, Transit, and Absorption of Glucose in Healthy Subjects and Patients With Type 2 Diabetes: A Randomized Controlled Trial
Open the PDF for The Glucagon-Like Peptide 1 Receptor Agonist Exenatide Inhibits Small Intestinal Motility, Flow, Transit, and Absorption of Glucose in Healthy Subjects and Patients With Type 2 Diabetes: A Randomized Controlled Trial in another window
Includes: Supplementary data
Journal Articles

Small Intestinal Glucose Exposure Determines the Magnitude of the Incretin Effect in Health and Type 2 Diabetes

Chinmay S. Marathe, Christopher K. Rayner, Michelle Bound, Helen Checklin, Scott Standfield, Judith Wishart, Kylie Lange, Karen L. Jones, Michael Horowitz
Journal: Diabetes
Diabetes 2014;63(8):2668–2675
https://doi.org/10.2337/db13-1757
Published: 17 July 2014
View article titled, Small Intestinal Glucose Exposure Determines the Magnitude of the Incretin Effect in Health and Type 2 Diabetes
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Journal Articles

Effects of Sitagliptin on Glycemia, Incretin Hormones, and Antropyloroduodenal Motility in Response to Intraduodenal Glucose Infusion in Healthy Lean and Obese Humans and Patients With Type 2 Diabetes Treated With or Without Metformin

Tongzhi Wu, Jing Ma, Michelle J. Bound, Helen Checklin, Carolyn F. Deacon, Karen L. Jones, Michael Horowitz, Christopher K. Rayner
Journal: Diabetes
Diabetes 2014;63(8):2776–2787
https://doi.org/10.2337/db13-1627
Published: 17 July 2014
View article titled, Effects of Sitagliptin on Glycemia, Incretin Hormones, and Antropyloroduodenal Motility in Response to Intraduodenal Glucose Infusion in Healthy Lean and Obese Humans and Patients With Type 2 Diabetes Treated With or Without Metformin
Open the PDF for Effects of Sitagliptin on Glycemia, Incretin Hormones, and Antropyloroduodenal Motility in Response to Intraduodenal Glucose Infusion in Healthy Lean and Obese Humans and Patients With Type 2 Diabetes Treated With or Without Metformin in another window
Journal Articles

Comparative Effects of Prolonged and Intermittent Stimulation of the Glucagon-Like Peptide 1 Receptor on Gastric Emptying and Glycemia

Mahesh M. Umapathysivam, Michael Y. Lee, Karen L. Jones, Christopher E. Annink, Caroline E. Cousins, Laurence G. Trahair, Chris K. Rayner, Marianne J. Chapman, Michael A. Nauck, Michael Horowitz, Adam M. Deane
Journal: Diabetes
Diabetes 2014;63(2):785–790
https://doi.org/10.2337/db13-0893
Published: 16 January 2014
View article titled, Comparative Effects of Prolonged and Intermittent Stimulation of the Glucagon-Like Peptide 1 Receptor on Gastric Emptying and Glycemia
Open the PDF for Comparative Effects of Prolonged and Intermittent Stimulation of the Glucagon-Like Peptide 1 Receptor on Gastric Emptying and Glycemia in another window
Includes: Supplementary data