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Kazuwa Nakao
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Journal Articles

Fat Mass Reduction With Adipocyte Hypertrophy and Insulin Resistance in Heterozygous PPARγ Mutant Rats

Valentino Gumbilai, Ken Ebihara, Megumi Aizawa-Abe, Chihiro Ebihara, Mingming Zhao, Yuji Yamamoto, Tomoji Mashimo, Kiminori Hosoda, Tadao Serikawa, Kazuwa Nakao
Journal: Diabetes
Diabetes 2016;65(10):2954–2965
https://doi.org/10.2337/db15-1422
Published: 05 July 2016
View article titled, Fat Mass Reduction With Adipocyte Hypertrophy and Insulin Resistance in Heterozygous PPARγ Mutant Rats
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Includes: Supplementary data
Journal Articles

Intracerebroventricular Administration of C-Type Natriuretic Peptide Suppresses Food Intake via Activation of the Melanocortin System in Mice

Nobuko Yamada-Goto, Goro Katsuura, Ken Ebihara, Megumi Inuzuka, Yukari Ochi, Yui Yamashita, Toru Kusakabe, Akihiro Yasoda, Noriko Satoh-Asahara, Hiroyuki Ariyasu, Kiminori Hosoda, Kazuwa Nakao
Journal: Diabetes
Diabetes 2013;62(5):1500–1504
https://doi.org/10.2337/db12-0718
Published: 16 April 2013
View article titled, Intracerebroventricular Administration of C-Type Natriuretic Peptide Suppresses Food Intake via Activation of the Melanocortin System in Mice
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Includes: Supplementary data
Journal Articles

Therapeutic Impact of Leptin on Diabetes, Diabetic Complications, and Longevity in Insulin-Deficient Diabetic Mice

Masaki Naito, Junji Fujikura, Ken Ebihara, Fumiko Miyanaga, Hideki Yokoi, Toru Kusakabe, Yuji Yamamoto, Cheol Son, Masashi Mukoyama, Kiminori Hosoda, Kazuwa Nakao
Journal: Diabetes
Diabetes 2011;60(9):2265–2273
https://doi.org/10.2337/db10-1795
Published: 20 August 2011
View article titled, Therapeutic Impact of Leptin on Diabetes, Diabetic Complications, and Longevity in Insulin-Deficient Diabetic Mice
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Journal Articles

Natriuretic Peptides/cGMP/cGMP-Dependent Protein Kinase Cascades Promote Muscle Mitochondrial Biogenesis and Prevent Obesity

Kazutoshi Miyashita, Hiroshi Itoh, Hirokazu Tsujimoto, Naohisa Tamura, Yasutomo Fukunaga, Masakatsu Sone, Kenichi Yamahara, Daisuke Taura, Megumi Inuzuka, Takuhiro Sonoyama, Kazuwa Nakao
Journal: Diabetes
Diabetes 2009;58(12):2880–2892
https://doi.org/10.2337/db09-0393
Published: 18 August 2009
View article titled, Natriuretic Peptides/cGMP/cGMP-Dependent Protein Kinase Cascades Promote Muscle Mitochondrial Biogenesis and Prevent Obesity
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Includes: Supplementary data
Journal Articles

Altered Gene Expression Related to Glomerulogenesis and Podocyte Structure in Early Diabetic Nephropathy of db/db Mice and Its Restoration by Pioglitazone

Hisashi Makino, Yoshihiro Miyamoto, Kazutomo Sawai, Kiyoshi Mori, Masashi Mukoyama, Kazuwa Nakao, Yasunao Yoshimasa, Shin-ichi Suga
Journal: Diabetes
Diabetes 2006;55(10):2747–2756
https://doi.org/10.2337/db05-1683
Published: 01 October 2006
View article titled, Altered Gene Expression Related to Glomerulogenesis and Podocyte Structure in Early Diabetic Nephropathy of <em>db/db</em> Mice and Its Restoration by Pioglitazone
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Journal Articles

Skeletal Muscle AMP-Activated Protein Kinase Phosphorylation Parallels Metabolic Phenotype in Leptin Transgenic Mice Under Dietary Modification

Tomohiro Tanaka, Shuji Hidaka, Hiroaki Masuzaki, Shintaro Yasue, Yasuhiko Minokoshi, Ken Ebihara, Hideki Chusho, Yoshihiro Ogawa, Taro Toyoda, Kenji Sato, Fumiko Miyanaga, Muneya Fujimoto, Tsutomu Tomita, Toru Kusakabe, Nozomi Kobayashi, Hideki Tanioka, Tatsuya Hayashi, Kiminori Hosoda, Hironobu Yoshimatsu, Toshiie Sakata, Kazuwa Nakao
Journal: Diabetes
Diabetes 2005;54(8):2365–2374
https://doi.org/10.2337/diabetes.54.8.2365
Published: 01 August 2005
View article titled, Skeletal Muscle AMP-Activated Protein Kinase Phosphorylation Parallels Metabolic Phenotype in Leptin Transgenic Mice Under Dietary Modification
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Journal Articles

Leptin Stimulates Ischemia-Induced Retinal Neovascularization: Possible Role of Vascular Endothelial Growth Factor Expressed in Retinal Endothelial Cells

Eri Suganami, Hitoshi Takagi, Hirokazu Ohashi, Kiyoshi Suzuma, Izumi Suzuma, Hideyasu Oh, Daisuke Watanabe, Tomonari Ojima, Takayoshi Suganami, Yasushi Fujio, Kazuwa Nakao, Yoshihiro Ogawa, Nagahisa Yoshimura
Journal: Diabetes
Diabetes 2004;53(9):2443–2448
https://doi.org/10.2337/diabetes.53.9.2443
Published: 01 September 2004
View article titled, Leptin Stimulates Ischemia-Induced Retinal Neovascularization: <subtitle>Possible Role of Vascular Endothelial Growth Factor Expressed in Retinal Endothelial Cells</subtitle>
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Journal Articles

A Novel Homozygous Missense Mutation of Melanocortin-4 Receptor (MC4R) in a Japanese Woman With Severe Obesity

Hiromasa Kobayashi, Yoshihiro Ogawa, Mitsuyo Shintani, Ken Ebihara, Makiko Shimodahira, Toshio Iwakura, Megumu Hino, Takashi Ishihara, Katsuji Ikekubo, Hiroyuki Kurahachi, Kazuwa Nakao
Journal: Diabetes
Diabetes 2002;51(1):243–246
https://doi.org/10.2337/diabetes.51.1.243
Published: 01 January 2002
View article titled, A Novel Homozygous Missense Mutation of Melanocortin-4 Receptor (<em>MC4R</em>) in a Japanese Woman With Severe Obesity
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Journal Articles

Troglitazone Not Only Increases GLUT4 but Also Induces Its Translocation in Rat Adipocytes

Mitsuyo Shintani, Haruo Nishimura, Shin Yonemitsu, Yoshihiro Ogawa, Tatsuya Hayashi, Kiminori Hosoda, Gen Inoue, Kazuwa Nakao
Journal: Diabetes
Diabetes 2001;50(10):2296–2300
https://doi.org/10.2337/diabetes.50.10.2296
Published: 01 October 2001
View article titled, Troglitazone Not Only Increases GLUT4 but Also Induces Its Translocation in Rat Adipocytes
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Journal Articles

Transgenic Overexpression of Leptin Rescues Insulin Resistance and Diabetes in a Mouse Model of Lipoatrophic Diabetes

Ken Ebihara, Yoshihiro Ogawa, Hiroaki Masuzaki, Mitsuyo Shintani, Fumiko Miyanaga, Megumi Aizawa-Abe, Tatsuya Hayashi, Kiminori Hosoda, Gen Inoue, Yasunao Yoshimasa, Oksana Gavrilova, Marc L. Reitman, Kazuwa Nakao
Journal: Diabetes
Diabetes 2001;50(6):1440–1448
https://doi.org/10.2337/diabetes.50.6.1440
Published: 01 June 2001
View article titled, Transgenic Overexpression of Leptin Rescues Insulin Resistance and Diabetes in a Mouse Model of Lipoatrophic Diabetes
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Journal Articles

Troglitazone Induces GLUT4 Translocation in L6 Myotubes

Shin Yonemitsu, Haruo Nishimura, Mitsuyo Shintani, Ryou Inoue, Yuji Yamamoto, Hiroaki Masuzaki, Yoshihiro Ogawa, Kiminori Hosoda, Gen Inoue, Tatsuya Hayashi, Kazuwa Nakao
Journal: Diabetes
Diabetes 2001;50(5):1093–1101
https://doi.org/10.2337/diabetes.50.5.1093
Published: 01 May 2001
View article titled, Troglitazone Induces GLUT4 Translocation in L6 Myotubes
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Journal Articles

Ghrelin, an Endogenous Growth Hormone Secretagogue, Is a Novel Orexigenic Peptide That Antagonizes Leptin Action Through the Activation of Hypothalamic Neuropeptide Y/Y1 Receptor Pathway

Mitsuyo Shintani, Yoshihiro Ogawa, Ken Ebihara, Megumi Aizawa-Abe, Fumiko Miyanaga, Kazuhiko Takaya, Tatsuya Hayashi, Gen Inoue, Kiminori Hosoda, Masayasu Kojima, Kenji Kangawa, Kazuwa Nakao
Journal: Diabetes
Diabetes 2001;50(2):227–232
https://doi.org/10.2337/diabetes.50.2.227
Published: 01 February 2001
View article titled, Ghrelin, an Endogenous Growth Hormone Secretagogue, Is a Novel Orexigenic Peptide That Antagonizes Leptin Action Through the Activation of Hypothalamic Neuropeptide Y/Y1 Receptor Pathway
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Journal Articles

Differential Activation of Mitogen-Activated Protein Kinase by Insulin and Epidermal Growth Factor in 3T3-L1 Adipocytes: A Possible Involvement of PI3-Kinase in the Activation of the MAP Kinase by Insulin

Junko Suga, Yasunao Yoshimasa, Kazunori Yamada, Yuji Yamamoto, Gen Inoue, Motozumi Okamoto, Tatsuya Hayashi, Michika Shigemoto, Atsushi Kosaki, Hideshi Kuzuya, Kazuwa Nakao
Journal: Diabetes
Diabetes 1997;46(5):735–741
https://doi.org/10.2337/diab.46.5.735
Published: 01 May 1997
View article titled, Differential Activation of Mitogen-Activated Protein Kinase by Insulin and Epidermal Growth Factor in 3T3-L1 Adipocytes: A Possible Involvement of PI3-Kinase in the Activation of the MAP Kinase by Insulin
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Journal Articles

Insulin Suppresses Endothelial Secretion of C-Type Natriuretic Peptide, A Novel Endothelium-Derived Relaxing Peptide

Toshio Igaki, Hiroshi Itoh, Shin-ichi Suga, Yasato Komatsu, Yoshihiro Ogawa, Kentaro Doi, Takaaki Yoshimasa, Kazuwa Nakao
Journal: Diabetes
Diabetes 1996;45(Supplement_3):S62–S64
https://doi.org/10.2337/diab.45.3.S62
Published: 01 July 1996
View article titled, Insulin Suppresses Endothelial Secretion of C-Type Natriuretic Peptide, A Novel Endothelium-Derived Relaxing Peptide
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Journal Articles

Human Obese Gene Expression: Adipocyte-Specific Expression and Regional Differences in the Adipose Tissue

Hiroaki Masuzaki, Yoshihiro Ogawa, Naohi Isse, Noriko Satoh, Taku Okazaki, Michika Shigemoto, Kiyoshi Mori, Naohisa Tamura, Kiminori Hosoda, Yasunao Yoshimasa, Hisato Jingami, Teruo Kawada, Kazuwa Nakao
Journal: Diabetes
Diabetes 1995;44(7):855–858
https://doi.org/10.2337/diab.44.7.855
Published: 01 July 1995
View article titled, Human Obese Gene Expression: Adipocyte-Specific Expression and Regional Differences in the Adipose Tissue
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