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Meeting Abstracts

1489-P: GAD65_247-266 Is a Major Th1 Epitope in Japanese Patients with Acute-Onset Type 1 Diabetes

DAISUKE CHUJO, KUMIKO AJIMA, MAYA MATSUSHITA, CHIHARU TSUTSUMI, FUMITAKA HASEDA, AKIHISA IMAGAWA, TOSHIAKI HANAFUSA, HIROSHI KAJIO, MASAYUKI SHIMODA, KAZUYUKI TOBE

Diabetes 2024;73(Supplement_1):1489-P

https://doi.org/10.2337/db24-1489-P

Published: 14 June 2024

View article titled, 1489-P: GAD65<sub>247-266</sub> Is a Major Th1 Epitope in Japanese Patients with Acute-Onset Type 1 Diabetes

Meeting Abstracts

77-OR: Time in Range Is Associated with Glucagon/C-Peptide Index Ratio in Type 2 Diabetes Patients

MIKI KAMIGISHI, DAISUKE CHUJO, AKIKO TAKIKAWA, SHINYA INAGAWA, ASAKO ENKAKU, SEIICHIRO OHGAKU, ATSUSHI SATO, SHINNOSUKE MATSUKOSHI, HISAE HONOKI, SHIHO FUJISAKA, KAZUYUKI TOBE

Diabetes 2024;73(Supplement_1):77-OR

https://doi.org/10.2337/db24-77-OR

Published: 14 June 2024

View article titled, 77-OR: Time in Range Is Associated with Glucagon/C-Peptide Index Ratio in Type 2 Diabetes Patients

Meeting Abstracts

2017-LB: Comparison of Nuclear Preparation for Single-Nucleus RNA-seq of Adipose Tissue

YASUHIRO ONOGI, TSUTOMU WADA, SHIHO FUJISAKA, TOSHIYASU SASAOKA, KEITA IIDA, YUKINORI OKADA, MAKOTO KADOWAKI, SHIGERU SAITO, KAZUYUKI TOBE

Diabetes 2024;73(Supplement_1):2017-LB

https://doi.org/10.2337/db24-2017-LB

Published: 14 June 2024

View article titled, 2017-LB: Comparison of Nuclear Preparation for Single-Nucleus RNA-seq of Adipose Tissue

Meeting Abstracts

1683-P: Characteristics of Lifestyle, Dietary Nutrients, and Gut Microbiota Associated with Predisease State of Metabolic Syndrome in Japanese Adults

YOSHIYUKI WATANABE, SHIHO FUJISAKA, HISAE HONOKI, TOMONOBU KADO, AYUMI NISHIMURA, MUHAMMAD BILAL, MUHAMMAD RAHIL ASLAM, YOSHIKO IGARASHI, YOSHITOMO MORINAGA, KAZUYUKI TOBE

Diabetes 2024;73(Supplement_1):1683-P

https://doi.org/10.2337/db24-1683-P

Published: 14 June 2024

View article titled, 1683-P: Characteristics of Lifestyle, Dietary Nutrients, and Gut Microbiota Associated with Predisease State of Metabolic Syndrome in Japanese Adults

Meeting Abstracts

298-OR: Safety and Efficacy of Immunomodulatory Therapy Using Antithymocyte Globulin and Pegfilgrastim in Japanese Patients with Type 1 Diabetes—A Pilot Randomized Clinical Trial

DAISUKE CHUJO, ASAKO ENKAKU, MIKI KAMIGISHI, AKIKO TAKIKAWA, MAYA MATSUSHITA, MICHI KOBAYASHI, KOKO YAMAMOTO, TSUTOMU SATO, YOSHIHIRO YAMAMOTO, NORIO OHMAGARI, HAJIME OHYANAGI, MASAYUKI SHIMODA, KOHJIRO UEKI, HIROSHI KAJIO, KAZUYUKI TOBE

Diabetes 2023;72(Supplement_1):298-OR

https://doi.org/10.2337/db23-298-OR

Published: 20 June 2023

View article titled, 298-OR: Safety and Efficacy of Immunomodulatory Therapy Using Antithymocyte Globulin and Pegfilgrastim in Japanese Patients with Type 1 Diabetes—A Pilot Randomized Clinical Trial

Meeting Abstracts

1672-P: Isoxanthohumol Improves Obesity and Glucose Metabolism via Regulation of Gut Barrier and Intestinal Lipid Absorption with a Bloom of Akkermansia muciniphila

YOSHIYUKI WATANABE, SHIHO FUJISAKA, SHIRO WATANABE, AYUMI NISHIMURA, TOMONOBU KADO, MUHAMMAD RAHIL ASLAM, MUHAMMAD BILAL, YOSHITOMO MORINAGA, KAZUYUKI TOBE

Diabetes 2023;72(Supplement_1):1672-P

https://doi.org/10.2337/db23-1672-P

Published: 20 June 2023

View article titled, 1672-P: Isoxanthohumol Improves Obesity and Glucose Metabolism via Regulation of Gut Barrier and Intestinal Lipid Absorption with a Bloom of <em>Akkermansia muciniphila</em>

Meeting Abstracts

1551-P: Association between Short-Term Postprandial C-Peptide Index Recovery during Hospitalization and Future Glycemic Control in Patients with Type 2 Diabetes

ASAKO ENKAKU, DAISUKE CHUJO, MIKI KAMIGISHI, SHINYA INAGAWA, WAKA SAKAI, SHINNOSUKE MATSUKOSHI, AKIKO TAKIKAWA, SHIHO FUJISAKA, KAZUYUKI TOBE

Diabetes 2023;72(Supplement_1):1551-P

https://doi.org/10.2337/db23-1551-P

Published: 20 June 2023

View article titled, 1551-P: Association between Short-Term Postprandial C-Peptide Index Recovery during Hospitalization and Future Glycemic Control in Patients with Type 2 Diabetes

Meeting Abstracts

1628-P: Role of CD38 in the Regulation of Muscle Stem Cell Functions in Aged Mice

ALLAH NAWAZ, KEISUKE YAKU, ISHTIAQ JEELANI, KAZUYUKI TOBE, TAKASHI NAKAGAWA

Diabetes 2023;72(Supplement_1):1628-P

https://doi.org/10.2337/db23-1628-P

Published: 20 June 2023

View article titled, 1628-P: Role of CD38 in the Regulation of Muscle Stem Cell Functions in Aged Mice

Meeting Abstracts

1623-P: Identification of Gut Microbes That Prevents Metabolic Syndrome in Healthy Japanese Adults

HISAE HONOKI, SHIHO FUJISAKA, YOSHIYUKI WATANABE, MAKITO OKU, YUKI KONDO, AYUMI NISHIMURA, TOMONOBU KADO, MUHAMMAD BILAL, ASAKO ENKAKU, AKIKO TAKIKAWA, DAISUKE CHUJO, YOSHITOMO MORINAGA, KAZUYUKI TOBE

Diabetes 2023;72(Supplement_1):1623-P

https://doi.org/10.2337/db23-1623-P

Published: 20 June 2023

View article titled, 1623-P: Identification of Gut Microbes That Prevents Metabolic Syndrome in Healthy Japanese Adults

Meeting Abstracts

1987-P: Nampt Deletion Changes Metabolism in Adipose Tissue and Prevents Diet-Induced Obesity

KEISUKE OKABE, ALLAH NAWAZ, SHIHO FUJISAKA, KUNIMASA YAGI, TOMONOBU KADO, ISAO USUI, TAKASHI NAKAGAWA, KAZUYUKI TOBE

Diabetes 2019;68(Supplement_1):1987-P

https://doi.org/10.2337/db19-1987-P

Published: 01 June 2019

View article titled, 1987-P: Nampt Deletion Changes Metabolism in Adipose Tissue and Prevents Diet-Induced Obesity

Meeting Abstracts

188-OR: Partial Depletion of CD206 M2-Like Macrophages Enhances Preadipocyte Differentiation via Reduction of Wnt Signaling

ALLAH NAWAZ, TAKASHI NAKAGAWA, KUNIMASA YAGI, SHIHO FUJISAKA, KAZUYUKI TOBE, KEISUKE OKABE, TOMONOBU KADO, JIANHUI LIU, MUHAMMAD BILAL

Diabetes 2019;68(Supplement_1):188-OR

https://doi.org/10.2337/db19-188-OR

Published: 01 June 2019

View article titled, 188-OR: Partial Depletion of CD206 M2-Like Macrophages Enhances Preadipocyte Differentiation via Reduction of Wnt Signaling

Meeting Abstracts

Depletion of CD2M2-Like Macrophages Promotes the Browning of the White Adipose Tissue

ALLAH NAWAZ, SHIHO FUJISAKA, ISAO USUI, KUNIMASA YAGI, TAKASHI NAKAGAWA, TOMONOBU KADO, KAZUYUKI TOBE, YOSHIKO IGARASHI, KEISUKE OKABE, KUMIKO SAEKI

Diabetes 2018;67(Supplement_1):1749-P

https://doi.org/10.2337/db18-1749-P

Published: 01 July 2018

View article titled, Depletion of CD2M2-Like Macrophages Promotes the Browning of the White Adipose Tissue

Meeting Abstracts

Serum Levels of Soluble LR11 Are Associated with Insulin Resistance in the Patients with Type 2 Diabetes Mellitus

HIROYUKI UNOKI-KUBOTA, MEIZI JIANG, HIROSHI KAJIO, RITSUKO YAMAMOTO-HONDA, KAZUYUKI TOBE, MITSUHIKO NODA, HIDEAKI BUJO, YASUSHI KABURAGI

Diabetes 2018;67(Supplement_1):1683-P

https://doi.org/10.2337/db18-1683-P

Published: 01 July 2018

View article titled, Serum Levels of Soluble LR11 Are Associated with Insulin Resistance in the Patients with Type 2 Diabetes Mellitus

Meeting Abstracts

Bofutsushosan Improves Gut Barrier Function with a Bloom of Akkermansia Muciniphila and Improves Glucose Metabolism in Diet-Induced Obese Mice

SHIHO FUJISAKA, ISAO USUI, ALLAH NAWAZ, YOSHIKO IGARASHI, TOMONOBU KADO, KEISUKE OKABE, KUNIMASA YAGI, TAKASHI NAKAGAWA, KAZUYUKI TOBE

Diabetes 2018;67(Supplement_1):1990-P

https://doi.org/10.2337/db18-1990-P

Published: 01 July 2018

View article titled, Bofutsushosan Improves Gut Barrier Function with a Bloom of Akkermansia Muciniphila and Improves Glucose Metabolism in Diet-Induced Obese Mice

Meeting Abstracts

Macrophages React to Postprandial Signals and Regulate the Response to Feeding through Akt-mTOR–Dependent Production of IL-10

GOTARO TODA, NOZOMU KAMEI, KOTARO SOEDA, YUKARI MASUDA, YOSHIHIKO IZUMIDA, NAOKI KOBAYASHI, TAKAYOSI SASAKO, KAZUYUKI TOBE, MORRIS J. BIRNBAUM, TAKASHI KADOWAKI, KOHJIRO UEKI

Diabetes 2018;67(Supplement_1):359-OR

https://doi.org/10.2337/db18-359-OR

Published: 01 July 2018

View article titled, Macrophages React to Postprandial Signals and Regulate the Response to Feeding through Akt-mTOR–Dependent Production of IL-10

Meeting Abstracts

NAD-Mediated Metabolic Reprogramming Epigenetically Regulates Gene Expression to Promote Preadipocyte Differentiation

KEISUKE OKABE, ISAO USUI, ALLAH NAWAZ, SHIHO FUJISAKA, TOMONOBU KADO, YOSHIKO IGARASHI, KUNIMASA YAGI, KAZUYUKI TOBE, TAKASHI NAKAGAWA

Diabetes 2018;67(Supplement_1):360-OR

https://doi.org/10.2337/db18-360-OR

Published: 01 July 2018

View article titled, NAD-Mediated Metabolic Reprogramming Epigenetically Regulates Gene Expression to Promote Preadipocyte Differentiation

Journal Articles

HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance

Diabetes 2016;65(12):3649–3659

https://doi.org/10.2337/db16-0012

Published: 13 September 2016

View article titled, HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance

Includes: Supplementary data

Journal Articles

Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India

Diabetes 2013;62(5):1746–1755

https://doi.org/10.2337/db12-1077

Published: 16 April 2013

View article titled, Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India

Includes: Supplementary data

Journal Articles

Loss of Pdk1-Foxo1 Signaling in Myeloid Cells Predisposes to Adipose Tissue Inflammation and Insulin Resistance

Yoshinaga Kawano, Jun Nakae, Nobuyuki Watanabe, Shiho Fujisaka, Kristy Iskandar, Risa Sekioka, Yoshitake Hayashi, Kazuyuki Tobe, Masato Kasuga, Tetsuo Noda, Akihiko Yoshimura, Masafumi Onodera, Hiroshi Itoh

Diabetes 2012;61(8):1935–1948

https://doi.org/10.2337/db11-0770

Published: 17 July 2012

View article titled, Loss of Pdk1-Foxo1 Signaling in Myeloid Cells Predisposes to Adipose Tissue Inflammation and Insulin Resistance

Includes: Supplementary data

Journal Articles

The Radioprotective 105/MD-1 Complex Contributes to Diet-Induced Obesity and Adipose Tissue Inflammation

Diabetes 2012;61(5):1199–1209

https://doi.org/10.2337/db11-1182

Published: 13 April 2012

View article titled, The Radioprotective 105/MD-1 Complex Contributes to Diet-Induced Obesity and Adipose Tissue Inflammation

Includes: Supplementary data

NARROW

1489-P: GAD65_247-266 Is a Major Th1 Epitope in Japanese Patients with Acute-Onset Type 1 Diabetes

77-OR: Time in Range Is Associated with Glucagon/C-Peptide Index Ratio in Type 2 Diabetes Patients

2017-LB: Comparison of Nuclear Preparation for Single-Nucleus RNA-seq of Adipose Tissue

1683-P: Characteristics of Lifestyle, Dietary Nutrients, and Gut Microbiota Associated with Predisease State of Metabolic Syndrome in Japanese Adults

298-OR: Safety and Efficacy of Immunomodulatory Therapy Using Antithymocyte Globulin and Pegfilgrastim in Japanese Patients with Type 1 Diabetes—A Pilot Randomized Clinical Trial

1672-P: Isoxanthohumol Improves Obesity and Glucose Metabolism via Regulation of Gut Barrier and Intestinal Lipid Absorption with a Bloom of Akkermansia muciniphila

1551-P: Association between Short-Term Postprandial C-Peptide Index Recovery during Hospitalization and Future Glycemic Control in Patients with Type 2 Diabetes

1628-P: Role of CD38 in the Regulation of Muscle Stem Cell Functions in Aged Mice

1623-P: Identification of Gut Microbes That Prevents Metabolic Syndrome in Healthy Japanese Adults

1987-P: Nampt Deletion Changes Metabolism in Adipose Tissue and Prevents Diet-Induced Obesity

188-OR: Partial Depletion of CD206 M2-Like Macrophages Enhances Preadipocyte Differentiation via Reduction of Wnt Signaling

Depletion of CD2M2-Like Macrophages Promotes the Browning of the White Adipose Tissue

Serum Levels of Soluble LR11 Are Associated with Insulin Resistance in the Patients with Type 2 Diabetes Mellitus

Bofutsushosan Improves Gut Barrier Function with a Bloom of Akkermansia Muciniphila and Improves Glucose Metabolism in Diet-Induced Obese Mice

Macrophages React to Postprandial Signals and Regulate the Response to Feeding through Akt-mTOR–Dependent Production of IL-10

NAD-Mediated Metabolic Reprogramming Epigenetically Regulates Gene Expression to Promote Preadipocyte Differentiation

HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance

Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India

Loss of Pdk1-Foxo1 Signaling in Myeloid Cells Predisposes to Adipose Tissue Inflammation and Insulin Resistance

The Radioprotective 105/MD-1 Complex Contributes to Diet-Induced Obesity and Adipose Tissue Inflammation

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