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Keith N. Frayn
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Journal Articles

Distinct Developmental Profile of Lower-Body Adipose Tissue Defines Resistance Against Obesity-Associated Metabolic Complications

Free
Katherine E. Pinnick, George Nicholson, Konstantinos N. Manolopoulos, Siobhán E. McQuaid, Philippe Valet, Keith N. Frayn, Nathan Denton, Josine L. Min, Krina T. Zondervan, Jan Fleckner, the MolPAGE Consortium, Mark I. McCarthy, Chris C. Holmes, Fredrik Karpe
Journal: Diabetes
Diabetes 2014;63(11):3785–3797
https://doi.org/10.2337/db14-0385
Published: 13 October 2014
View articletitled, Distinct Developmental Profile of Lower-Body Adipose Tissue Defines Resistance Against Obesity-Associated Metabolic Complications
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Includes: Supplementary data
Journal Articles

Metabolic Signatures of Human Adipose Tissue Hypoxia in Obesity

Open Access
Leanne Hodson, Sandy M. Humphreys, Fredrik Karpe, Keith N. Frayn
Journal: Diabetes
Diabetes 2013;62(5):1417–1425
https://doi.org/10.2337/db12-1032
Published: 16 April 2013
View articletitled, Metabolic Signatures of Human Adipose Tissue Hypoxia in Obesity
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Includes: Supplementary data
Journal Articles

Gluteofemoral Adipose Tissue Plays a Major Role in Production of the Lipokine Palmitoleate in Humans

Open Access
Katherine E. Pinnick, Matt J. Neville, Barbara A. Fielding, Keith N. Frayn, Fredrik Karpe, Leanne Hodson
Journal: Diabetes
Diabetes 2012;61(6):1399–1403
https://doi.org/10.2337/db11-1810
Published: 14 May 2012
View articletitled, Gluteofemoral Adipose Tissue Plays a Major Role in Production of the Lipokine Palmitoleate in Humans
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Includes: Supplementary data
Journal Articles

Fatty Acids, Obesity, and Insulin Resistance: Time for a Reevaluation

Open Access
Fredrik Karpe, Julian R. Dickmann, Keith N. Frayn
Journal: Diabetes
Diabetes 2011;60(10):2441–2449
https://doi.org/10.2337/db11-0425
Published: 16 September 2011
View articletitled, Fatty Acids, Obesity, and Insulin Resistance: Time for a Reevaluation
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Includes: Supplementary data
Journal Articles

Downregulation of Adipose Tissue Fatty Acid Trafficking in Obesity: A Driver for Ectopic Fat Deposition?

Open Access
Siobhán E. McQuaid, Leanne Hodson, Matthew J. Neville, A. Louise Dennis, Jane Cheeseman, Sandy M. Humphreys, Toralph Ruge, Marjorie Gilbert, Barbara A. Fielding, Keith N. Frayn, Fredrik Karpe
Journal: Diabetes
Diabetes 2011;60(1):47–55
https://doi.org/10.2337/db10-0867
Published: 13 October 2010
View articletitled, Downregulation of Adipose Tissue Fatty Acid Trafficking in Obesity: A Driver for Ectopic Fat Deposition?
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Includes: Supplementary data
Journal Articles

Femoral Adipose Tissue May Accumulate the Fat That Has Been Recycled as VLDL and Nonesterified Fatty Acids

Open Access
Siobhán E. McQuaid, Sandy M. Humphreys, Leanne Hodson, Barbara A. Fielding, Fredrik Karpe, Keith N. Frayn
Journal: Diabetes
Diabetes 2010;59(10):2465–2473
https://doi.org/10.2337/db10-0678
Published: 03 August 2010
View articletitled, Femoral Adipose Tissue May Accumulate the Fat That Has Been Recycled as VLDL and Nonesterified Fatty Acids
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Includes: Supplementary data
Journal Articles

Elevated Expression of Osteopontin May Be Related to Adipose Tissue Macrophage Accumulation and Liver Steatosis in Morbid Obesity

Free
Adeline Bertola, Vanessa Deveaux, Stéphanie Bonnafous, Déborah Rousseau, Rodolphe Anty, Abdelilah Wakkach, Moncef Dahman, Joan Tordjman, Karine Clément, Siobhán E. McQuaid, Keith N. Frayn, Pierre-Michel Huet, Jean Gugenheim, Sophie Lotersztajn, Yannick Le Marchand-Brustel, Albert Tran, Philippe Gual
Journal: Diabetes
Diabetes 2009;58(1):125–133
https://doi.org/10.2337/db08-0400
Published: 01 January 2009
View articletitled, Elevated Expression of Osteopontin May Be Related to Adipose Tissue Macrophage Accumulation and Liver Steatosis in Morbid Obesity
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Journal Articles

Activation of Peroxisome Proliferator–Activated Receptor (PPAR)δ Promotes Reversal of Multiple Metabolic Abnormalities, Reduces Oxidative Stress, and Increases Fatty Acid Oxidation in Moderately Obese Men

Free
Ulf Risérus, Dennis Sprecher, Tony Johnson, Eric Olson, Sandra Hirschberg, Aixue Liu, Zeke Fang, Priti Hegde, Duncan Richards, Leli Sarov-Blat, Jay C. Strum, Samar Basu, Jane Cheeseman, Barbara A. Fielding, Sandy M. Humphreys, Theodore Danoff, Niall R. Moore, Peter Murgatroyd, Stephen O'Rahilly, Pauline Sutton, Tim Willson, David Hassall, Keith N. Frayn, Fredrik Karpe
Journal: Diabetes
Diabetes 2008;57(2):332–339
https://doi.org/10.2337/db07-1318
Published: 01 February 2008
View articletitled, Activation of Peroxisome Proliferator–Activated Receptor (PPAR)δ Promotes Reversal of Multiple Metabolic Abnormalities, Reduces Oxidative Stress, and Increases Fatty Acid Oxidation in Moderately Obese Men
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Includes: Supplementary data
Journal Articles

The Contribution of Splanchnic Fat to VLDL Triglyceride Is Greater in Insulin-Resistant Than Insulin-Sensitive Men and Women : Studies in the Postprandial State

Free
Leanne Hodson, Alex S.T. Bickerton, Siobhán E. McQuaid, Rachel Roberts, Fredrik Karpe, Keith N. Frayn, Barbara A. Fielding
Journal: Diabetes
Diabetes 2007;56(10):2433–2441
https://doi.org/10.2337/db07-0654
Published: 01 October 2007
View articletitled, The Contribution of Splanchnic Fat to VLDL Triglyceride Is Greater in Insulin-Resistant Than Insulin-Sensitive Men and Women : Studies in the Postprandial State
Open the PDF for The Contribution of Splanchnic Fat to VLDL Triglyceride Is Greater in Insulin-Resistant Than Insulin-Sensitive Men and Women : Studies in the Postprandial State in another window
Includes: Supplementary data
Journal Articles

Preferential Uptake of Dietary Fatty Acids in Adipose Tissue and Muscle in the Postprandial Period

Free
Alex S.T. Bickerton, Rachel Roberts, Barbara A. Fielding, Leanne Hodson, Ellen E. Blaak, Anton J.M. Wagenmakers, Marjorie Gilbert, Fredrik Karpe, Keith N. Frayn
Journal: Diabetes
Diabetes 2007;56(1):168–176
https://doi.org/10.2337/db06-0822
Published: 01 January 2007
View articletitled, Preferential Uptake of Dietary Fatty Acids in Adipose Tissue and Muscle in the Postprandial Period
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Journal Articles

Oscillations of Fatty Acid and Glycerol Release From Human Subcutaneous Adipose Tissue In Vivo

Free
Fredrik Karpe, Barbara A. Fielding, Simon W. Coppack, Victor J. Lawrence, Ian A. Macdonald, Keith N. Frayn
Journal: Diabetes
Diabetes 2005;54(5):1297–1303
https://doi.org/10.2337/diabetes.54.5.1297
Published: 01 May 2005
View articletitled, Oscillations of Fatty Acid and Glycerol Release From Human Subcutaneous Adipose Tissue In Vivo
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Journal Articles

Rosiglitazone Increases Indexes of Stearoyl-CoA Desaturase Activity in Humans: Link to Insulin Sensitization and the Role of Dominant-Negative Mutation in Peroxisome Proliferator-Activated Receptor-γ

Free
Ulf Risérus, Garry D. Tan, Barbara A. Fielding, Matt J. Neville, Jenny Currie, David B. Savage, V. Krishna Chatterjee, Keith N. Frayn, Stephen O’Rahilly, Fredrik Karpe
Journal: Diabetes
Diabetes 2005;54(5):1379–1384
https://doi.org/10.2337/diabetes.54.5.1379
Published: 01 May 2005
View articletitled, Rosiglitazone Increases Indexes of Stearoyl-CoA Desaturase Activity in Humans: Link to Insulin Sensitization and the Role of Dominant-Negative Mutation in Peroxisome Proliferator-Activated Receptor-γ
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Journal Articles

Regulation of Dietary Fatty Acid Entrapment in Subcutaneous Adipose Tissue and Skeletal Muscle

Free
Kevin Evans, Graham C. Burdge, Stephen A. Wootton, Mo L. Clark, Keith N. Frayn
Journal: Diabetes
Diabetes 2002;51(9):2684–2690
https://doi.org/10.2337/diabetes.51.9.2684
Published: 01 September 2002
View articletitled, Regulation of Dietary Fatty Acid Entrapment in Subcutaneous Adipose Tissue and Skeletal Muscle
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Journal Articles

Impaired Postprandial Adipose Tissue Blood Flow Response Is Related to Aspects of Insulin Sensitivity

Free
Fredrik Karpe, Barbara A. Fielding, Vera Ilic, Ian A. Macdonald, Lucinda K.M. Summers, Keith N. Frayn
Journal: Diabetes
Diabetes 2002;51(8):2467–2473
https://doi.org/10.2337/diabetes.51.8.2467
Published: 01 August 2002
View articletitled, Impaired Postprandial Adipose Tissue Blood Flow Response Is Related to Aspects of Insulin Sensitivity
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