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Kenju Shimomura
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Journal Articles

Involvement of cAMP/EPAC/TRPM2 Activation in Glucose- and Incretin-Induced Insulin Secretion

Masashi Yosida, Katsuya Dezaki, Kunitoshi Uchida, Shiho Kodera, Nien V. Lam, Kiyonori Ito, Rauza S. Rita, Hodaka Yamada, Kenju Shimomura, San-e Ishikawa, Hitoshi Sugawara, Masanobu Kawakami, Makoto Tominaga, Toshihiko Yada, Masafumi Kakei
Journal: Diabetes
Diabetes 2014;63(10):3394–3403
https://doi.org/10.2337/db13-1868
Published: 15 September 2014
View article titled, Involvement of cAMP/EPAC/TRPM2 Activation in Glucose- and Incretin-Induced Insulin Secretion
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Includes: Supplementary data
Journal Articles

A Mouse Model of Human Hyperinsulinism Produced by the E1506K Mutation in the Sulphonylurea Receptor SUR1

Kenju Shimomura, Maija Tusa, Michaela Iberl, Melissa F. Brereton, Stephan Kaizik, Peter Proks, Carolina Lahmann, Nagendra Yaluri, Shalem Modi, Hanna Huopio, Jarkko Ustinov, Timo Otonkoski, Markku Laakso, Frances M. Ashcroft
Journal: Diabetes
Diabetes 2013;62(11):3797–3806
https://doi.org/10.2337/db12-1611
Published: 18 October 2013
View article titled, A Mouse Model of Human Hyperinsulinism Produced by the E1506K Mutation in the Sulphonylurea Receptor SUR1
Open the PDF for A Mouse Model of Human Hyperinsulinism Produced by the E1506K Mutation in the Sulphonylurea Receptor SUR1 in another window
Includes: Supplementary data
Journal Articles

Role of the Transcription Factor Sox4 in Insulin Secretion and Impaired Glucose Tolerance

Michelle Goldsworthy, Alison Hugill, Helen Freeman, Emma Horner, Kenju Shimomura, Debora Bogani, Guido Pieles, Vesna Mijat, Ruth Arkell, Shoumo Bhattacharya, Frances M. Ashcroft, Roger D. Cox
Journal: Diabetes
Diabetes 2008;57(8):2234–2244
https://doi.org/10.2337/db07-0337
Published: 01 August 2008
View article titled, Role of the Transcription Factor <em>Sox4</em> in Insulin Secretion and Impaired Glucose Tolerance
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Includes: Supplementary data
Journal Articles

Long-Term Exposure to Glucose and Lipids Inhibits Glucose-Induced Insulin Secretion Downstream of Granule Fusion With Plasma Membrane

Charlotta S. Olofsson, Stephan Collins, Martin Bengtsson, Lena Eliasson, Albert Salehi, Kenju Shimomura, Andrei Tarasov, Cecilia Holm, Frances Ashcroft, Patrik Rorsman
Journal: Diabetes
Diabetes 2007;56(7):1888–1897
https://doi.org/10.2337/db06-1150
Published: 01 July 2007
View article titled, Long-Term Exposure to Glucose and Lipids Inhibits Glucose-Induced Insulin Secretion Downstream of Granule Fusion With Plasma Membrane
Open the PDF for Long-Term Exposure to Glucose and Lipids Inhibits Glucose-Induced Insulin Secretion Downstream of Granule Fusion With Plasma Membrane in another window
Includes: Supplementary data
Journal Articles

Mutations at the Same Residue (R50) of Kir6.2 (KCNJ11) That Cause Neonatal Diabetes Produce Different Functional Effects

Kenju Shimomura, Christophe A.J. Girard, Peter Proks, Joanna Nazim, Jonathan D. Lippiat, Franco Cerutti, Renata Lorini, Sian Ellard, Andrew T. Hattersley, Fabrizio Barbetti, Frances M. Ashcroft
Journal: Diabetes
Diabetes 2006;55(6):1705–1712
https://doi.org/10.2337/db05-1640
Published: 01 June 2006
View article titled, Mutations at the Same Residue (R50) of Kir6.2 (<em>KCNJ11</em>) That Cause Neonatal Diabetes Produce Different Functional Effects
Open the PDF for Mutations at the Same Residue (R50) of Kir6.2 (<em>KCNJ11</em>) That Cause Neonatal Diabetes Produce Different Functional Effects in another window