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Kenneth K.Y. Cheng
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Journal Articles

YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells

Free
Di Liu, Kevin Y. Yang, Vicken W. Chan, Wenchu Ye, Charing C.N. Chong, Chi Chiu Wang, Huating Wang, Bin Zhou, Kenneth K.Y. Cheng, Kathy O. Lui
Journal: Diabetes
Diabetes 2022;71(5):961–977
https://doi.org/10.2337/db21-0695
Published: 03 February 2022
View articletitled, YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells
Open the PDF for YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells in another window
Journal Articles

The Dysfunctional MDM2–p53 Axis in Adipocytes Contributes to Aging-Related Metabolic Complications by Induction of Lipodystrophy

Free
Zhuohao Liu, Leigang Jin, Jin-Kui Yang, Baile Wang, Kelvin K.L. Wu, Philip Hallenborg, Aimin Xu, Kenneth K.Y. Cheng
Journal: Diabetes
Diabetes 2018;67(11):2397–2409
https://doi.org/10.2337/db18-0684
Published: 21 August 2018
View articletitled, The Dysfunctional MDM2–p53 Axis in Adipocytes Contributes to Aging-Related Metabolic Complications by Induction of Lipodystrophy
Open the PDF for The Dysfunctional MDM2–p53 Axis in Adipocytes Contributes to Aging-Related Metabolic Complications by Induction of Lipodystrophy in another window
Includes: Supplementary data
Meeting Abstracts

Loss of Adipocyte MDM2 Causes Lipodystrophy by Inducing P53-Dependent Apoptosis and Senescence

Free
ZHUOHAO LIU, LEIGANG JIN, BAILE WANG, KENNETH K.Y. CHENG, AIMIN XU
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2027-P
https://doi.org/10.2337/db18-2027-P
Published: 01 July 2018
View articletitled, Loss of Adipocyte MDM2 Causes Lipodystrophy by Inducing P53-Dependent Apoptosis and Senescence
Journal Articles

Erratum. Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells. Diabetes 2007;56: 1387–1394

Free
Kenneth K.Y. Cheng, Karen S.L. Lam, Yu Wang, Yu Huang, David Carling, Donghai Wu, Chiwai Wong, Aimin Xu
Journal: Diabetes
Diabetes 2016;65(10):3218
https://doi.org/10.2337/db16-er10a
Published: 15 September 2016
View articletitled, Erratum. Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells. Diabetes 2007;56: 1387–1394
Open the PDF for Erratum. Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells. Diabetes 2007;56: 1387–1394 in another window
Journal Articles

Erratum. Adiponectin Prevents Diabetic Premature Senescence of Endothelial Progenitor Cells and Promotes Endothelial Repair by Suppressing the p38 MAP Kinase/p16INK4A Signaling Pathway. Diabetes 2010;59: 2949–2959

Free
Junlei Chang, Yiming Li, Yu Huang, Karen S.L. Lam, Ruby L.C. Hoo, Wing Tak Wong, Kenneth K.Y. Cheng, Yiqun Wang, Paul M. Vanhoutte, Aimin Xu
Journal: Diabetes
Diabetes 2016;65(10):3219
https://doi.org/10.2337/db16-er10b
Published: 15 September 2016
View articletitled, Erratum. Adiponectin Prevents Diabetic Premature Senescence of Endothelial Progenitor Cells and Promotes Endothelial Repair by Suppressing the p38 MAP Kinase/p16INK4A Signaling Pathway. Diabetes 2010;59: 2949–2959
Open the PDF for Erratum. Adiponectin Prevents Diabetic Premature Senescence of Endothelial Progenitor Cells and Promotes Endothelial Repair by Suppressing the p38 MAP Kinase/p16INK4A Signaling Pathway. Diabetes 2010;59: 2949–2959 in another window
Journal Articles

Erratum. APPL1 Counteracts Obesity-Induced Vascular Insulin Resistance and Endothelial Dysfunction by Modulating the Endothelial Production of Nitric Oxide and Endothelin-1 in Mice. Diabetes 2011;60: 3044–3054

Free
Yi Wang, Kenneth K.Y. Cheng, Karen S.L. Lam, Donghai Wu, Yu Wang, Yu Huang, Paul M. Vanhoutte, Gary Sweeney, Yiming Li, Aimin Xu
Journal: Diabetes
Diabetes 2016;65(10):3219
https://doi.org/10.2337/db16-er10c
Published: 15 September 2016
View articletitled, Erratum. APPL1 Counteracts Obesity-Induced Vascular Insulin Resistance and Endothelial Dysfunction by Modulating the Endothelial Production of Nitric Oxide and Endothelin-1 in Mice. Diabetes 2011;60: 3044–3054
Open the PDF for Erratum. APPL1 Counteracts Obesity-Induced Vascular Insulin Resistance and Endothelial Dysfunction by Modulating the Endothelial Production of Nitric Oxide and Endothelin-1 in Mice. Diabetes 2011;60: 3044–3054 in another window
Journal Articles

The Adaptor Protein APPL2 Inhibits Insulin-Stimulated Glucose Uptake by Interacting With TBC1D1 in Skeletal Muscle

Free
Kenneth K.Y. Cheng, Weidong Zhu, Bin Chen, Yu Wang, Donghai Wu, Gary Sweeney, Baile Wang, Karen S.L. Lam, Aimin Xu
Journal: Diabetes
Diabetes 2014;63(11):3748–3758
https://doi.org/10.2337/db14-0337
Published: 13 October 2014
View articletitled, The Adaptor Protein APPL2 Inhibits Insulin-Stimulated Glucose Uptake by Interacting With TBC1D1 in Skeletal Muscle
Open the PDF for The Adaptor Protein APPL2 Inhibits Insulin-Stimulated Glucose Uptake by Interacting With TBC1D1 in Skeletal Muscle in another window
Includes: Supplementary data
Journal Articles

APPL1 Counteracts Obesity-Induced Vascular Insulin Resistance and Endothelial Dysfunction by Modulating the Endothelial Production of Nitric Oxide and Endothelin-1 in Mice

Open Access
Yi Wang, Kenneth K.Y. Cheng, Karen S.L. Lam, Donghai Wu, Yu Wang, Yu Huang, Paul M. Vanhoutte, Gary Sweeney, Yiming Li, Aimin Xu
Journal: Diabetes
Diabetes 2011;60(11):3044–3054
https://doi.org/10.2337/db11-0666
Published: 17 October 2011
View articletitled, APPL1 Counteracts Obesity-Induced Vascular Insulin Resistance and Endothelial Dysfunction by Modulating the Endothelial Production of Nitric Oxide and Endothelin-1 in Mice
Open the PDF for APPL1 Counteracts Obesity-Induced Vascular Insulin Resistance and Endothelial Dysfunction by Modulating the Endothelial Production of Nitric Oxide and Endothelin-1 in Mice in another window
Includes: Supplementary data
Journal Articles

Adiponectin Prevents Diabetic Premature Senescence of Endothelial Progenitor Cells and Promotes Endothelial Repair by Suppressing the p38 MAP Kinase/p16INK4A Signaling Pathway

Open Access
Junlei Chang, Yiming Li, Yu Huang, Karen S.L. Lam, Ruby L.C. Hoo, Wing Tak Wong, Kenneth K.Y. Cheng, Yiqun Wang, Paul M. Vanhoutte, Aimin Xu
Journal: Diabetes
Diabetes 2010;59(11):2949–2959
https://doi.org/10.2337/db10-0582
Published: 29 August 2010
View articletitled, Adiponectin Prevents Diabetic Premature Senescence of Endothelial Progenitor Cells and Promotes Endothelial Repair by Suppressing the p38 MAP Kinase/p16INK4A Signaling Pathway
Open the PDF for Adiponectin Prevents Diabetic Premature Senescence of Endothelial Progenitor Cells and Promotes Endothelial Repair by Suppressing the p38 MAP Kinase/p16INK4A Signaling Pathway in another window
Includes: Supplementary data
Journal Articles

Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells

Free
Kenneth K.Y. Cheng, Karen S.L. Lam, Yu Wang, Yu Huang, David Carling, Donghai Wu, Chiwai Wong, Aimin Xu
Journal: Diabetes
Diabetes 2007;56(5):1387–1394
https://doi.org/10.2337/db06-1580
Published: 01 May 2007
View articletitled, Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells
Open the PDF for Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells in another window
Includes: Supplementary data