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Meeting Abstracts

1324-P: Short-Term Effects of Glycemia-Lowering Medications on ß-Cell Function in the GRADE Study

NEDA RASOULI, JEANINE ALBU, ROBERT M. COHEN, RALPH A. DEFRONZO, ELSA DIAZ, ALOKANANDA GHOSH, JOSE A. LUCHSINGER, JANET B. MCGILL, LAURE SAYYED KASSEM, WILLIAM SIVITZ, WILLIAM V. TAMBORLANE, KRISTINA UTZSCHNEIDER, NAJI YOUNES, STEVEN E. KAHN, GRADE RESEARCH GROUP
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1324-P
https://doi.org/10.2337/db22-1324-P
Published: 01 June 2022
View articletitled, 1324-P: Short-Term Effects of Glycemia-Lowering Medications on ß-Cell Function in the GRADE Study
Meeting Abstracts

1326-P: Baseline OGTT as a Predictor of Type 2 Diabetes Progression in the GRADE Study

KRISTINA UTZSCHNEIDER, NAJI YOUNES, NICOLE M. BUTERA, ASHOK BALASUBRAMANYAM, CYRUS DESOUZA, JONATHAN KRAKOFF, JOSHUA I. BARZILAY, RALPH A. DEFRONZO, RICHARD M. BERGENSTAL, TOM A. ELASY, WILLY VALENCIA, CHARLES MA, NEDA RASOULI, STEVEN E. KAHN, WILLIAM SIVITZ, GRADE RESEARCH GROUP
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1326-P
https://doi.org/10.2337/db22-1326-P
Published: 01 June 2022
View articletitled, 1326-P: Baseline OGTT as a Predictor of Type 2 Diabetes Progression in the GRADE Study
Journal Articles

Islet Autoimmunity Is Highly Prevalent and Associated With Diminished β-Cell Function in Patients With Type 2 Diabetes in the GRADE Study

Barbara Brooks-Worrell, Christiane S. Hampe, Erica G. Hattery, Brenda Palomino, Sahar Z. Zangeneh, Kristina Utzschneider, Steven E. Kahn, Mary E. Larkin, Mary L. Johnson, Kieren J. Mather, Naji Younes, Neda Rasouli, Cyrus Desouza, Robert M. Cohen, Jean Y. Park, Hermes J. Florez, Willy Marcos Valencia, GRADE β-cell Ancillary Study Network, Ali Shojaie, Jerry P. Palmer, Ashok Balasubramanyam
Journal: Diabetes
Diabetes 2022;71(6):1261–1271
https://doi.org/10.2337/db21-0590
Published: 21 January 2022
View articletitled, Islet Autoimmunity Is Highly Prevalent and Associated With Diminished β-Cell Function in Patients With Type 2 Diabetes in the GRADE Study
Open the PDF for Islet Autoimmunity Is Highly Prevalent and Associated With Diminished β-Cell Function in Patients With Type 2 Diabetes in the GRADE Study in another window
Meeting Abstracts

170-OR: Hypothalamic Gliosis Predicts Decline in Insulin Sensitivity over One Year in People with Obesity

JENNIFER L. ROSENBAUM, STEFAN SCHOEN, SUSAN J. MELHORN, MARY ROSALYNN DE LEON, MARY WEBB, KRISTINA UTZSCHNEIDER, ELLEN SCHUR
Journal: Diabetes
Diabetes 2021;70(Supplement_1):170-OR
https://doi.org/10.2337/db21-170-OR
Published: 01 June 2021
View articletitled, 170-OR: Hypothalamic Gliosis Predicts Decline in Insulin Sensitivity over One Year in People with Obesity
Meeting Abstracts

1600-P: One Hour OGTT Plasma Glucose as a Biomarker of ß-Cell Function

BRIAN T. LEGVOLD, AMANDA ZHANG, MARY K. RHEE, LISA R. STAIMEZ, KRISTINA UTZSCHNEIDER, LOUISE P. SAVOYE, JOHN R. PETRIE, BEVERLEY BALKAU, LAWRENCE S. PHILLIPS
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1600-P
https://doi.org/10.2337/db20-1600-P
Published: 01 June 2020
View articletitled, 1600-P: One Hour OGTT Plasma Glucose as a Biomarker of ß-Cell Function
Meeting Abstracts

254-OR: Islet Autoimmunity Is Highly Prevalent and Associated with Diminished Beta-Cell Function in Patients with Type 2 Diabetes (T2D) in the GRADE Study

BARBARA BROOKS-WORRELL, CHRISTIANE S. HAMPE, ERICA V. GONZALEZ, BRENDA M. PALOMINO, SAHAR Z. ZANGENEH, KRISTINA UTZSCHNEIDER, STEVEN E. KAHN, MARY E. LARKIN, MARY L. JOHNSON, KIEREN J. MATHER, NAJI YOUNES, NEDA RASOULI, CYRUS DESOUZA, ROBERT M. COHEN, JEAN Y. PARK, HERMES FLOREZ, WILLY MARCOS VALENCIA, GRADE BETA CELL ANCILLARY STUDY NETWORK, ALI SHOJAIE, JERRY P. PALMER, ASHOK BALASUBRAMANYAM, GRADE RESEARCH GROUP
Journal: Diabetes
Diabetes 2020;69(Supplement_1):254-OR
https://doi.org/10.2337/db20-254-OR
Published: 01 June 2020
View articletitled, 254-OR: Islet Autoimmunity Is Highly Prevalent and Associated with Diminished Beta-Cell Function in Patients with Type 2 Diabetes (T2D) in the GRADE Study
Meeting Abstracts

1779-P: Liraglutide + Metformin Delays Worsening of Glycemia in Adults with Impaired Glucose Tolerance (IGT) or Type 2 Diabetes (T2D)

SUSAN SAM, SHARON EDELSTEIN, KRISTINA UTZSCHNEIDER, TAMARA S. HANNON, ELENA BARENGOLTS, ANNY XIANG, DAVID A. EHRMANN, KIEREN J. MATHER, STEVEN E. KAHN, THE RISE CONSORTIUM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1779-P
https://doi.org/10.2337/db20-1779-P
Published: 01 June 2020
View articletitled, 1779-P: Liraglutide + Metformin Delays Worsening of Glycemia in Adults with Impaired Glucose Tolerance (IGT) or Type 2 Diabetes (T2D)
Meeting Abstracts

1794-P: Successful Standardization of a Hyperglycemic Clamp Method across Multiple Clinical Centers in the Restoring Insulin Secretion (RISE) Study

KIEREN J. MATHER, ASHLEY H. TJADEN, SILVA A. ARSLANIAN, KRISTINA UTZSCHNEIDER, SONIA CAPRIO, KRISTINA UTZSCHNEIDER, KAREN M. ATKINSON, MELANIE CREE-GREEN, KRISTEN J. NADEAU, THOMAS A. BUCHANAN, STEVEN E. KAHN, THE RISE CONSORTIUM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1794-P
https://doi.org/10.2337/db20-1794-P
Published: 01 June 2020
View articletitled, 1794-P: Successful Standardization of a Hyperglycemic Clamp Method across Multiple Clinical Centers in the Restoring Insulin Secretion (RISE) Study
Meeting Abstracts

1780-P: Differential Effects of Medications and Gastric Banding on OGTT-Modeled Measures of ß-Cell Function in Adults with IGT or Recent-Onset Type 2 Diabetes (T2D)

KRISTINA UTZSCHNEIDER, LAURE EL GHORMLI, SUSAN SAM, DAVID A. EHRMANN, KIEREN J. MATHER, ELENA BARENGOLTS, TAMARA S. HANNON, MARK TRIPPUTI, SHARON EDELSTEIN, ANDREA MARI, THE RISE CONSORTIUM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1780-P
https://doi.org/10.2337/db20-1780-P
Published: 01 June 2020
View articletitled, 1780-P: Differential Effects of Medications and Gastric Banding on OGTT-Modeled Measures of ß-Cell Function in Adults with IGT or Recent-Onset Type 2 Diabetes (T2D)
Meeting Abstracts

60-OR: OGTT Glucose Response Curves (GRC), Insulin Sensitivity (IS), and ß-Cell Function (ßCF) in RISE: Youth–Adult Contrast at Randomization and in Response to Interventions to Preserve ßCF

SILVA A. ARSLANIAN, LAURE EL GHORMLI, JOON YOUNG KIM, TAMARA S. HANNON, KIEREN J. MATHER, SONIA CAPRIO, ELENA BARENGOLTS, KRISTEN J. NADEAU, KRISTINA UTZSCHNEIDER, STEVEN E. KAHN, THE RISE CONSORTIUM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):60-OR
https://doi.org/10.2337/db20-60-OR
Published: 01 June 2020
View articletitled, 60-OR: OGTT Glucose Response Curves (GRC), Insulin Sensitivity (IS), and ß-Cell Function (ßCF) in RISE: Youth–Adult Contrast at Randomization and in Response to Interventions to Preserve ßCF
Meeting Abstracts

1679-P: Islet Autoimmunity in Adults with Impaired Glucose Tolerance (IGT) and Newly Diagnosed, Treatment-Naïve Type 2 Diabetes (NDX T2D) in the Restoring Insulin Secretion (RISE) Study

BARBARA BROOKS-WORRELL, ASHLEY H. TJADEN, SHARON EDELSTEIN, BRENDA M. PALOMINO, KRISTINA UTZSCHNEIDER, SILVA A. ARSLANIAN, KIEREN J. MATHER, THOMAS A. BUCHANAN, KRISTEN J. NADEAU, KAREN M. ATKINSON, ELENA BARENGOLTS, STEVEN E. KAHN, JERRY P. PALMER, RISE CONSORTIUM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1679-P
https://doi.org/10.2337/db20-1679-P
Published: 01 June 2020
View articletitled, 1679-P: Islet Autoimmunity in Adults with Impaired Glucose Tolerance (IGT) and Newly Diagnosed, Treatment-Naïve Type 2 Diabetes (NDX T2D) in the Restoring Insulin Secretion (RISE) Study
Meeting Abstracts

229-OR: The Gut Microbiome in Adults with Prediabetes and Effect of Dietary Glycemic Index

KRISTINA UTZSCHNEIDER, MARIAN L. NEUHOUSER, KATHERINE M. NEWTON, KARA BREYMEYER, MEREDITH A. HULLAR
Journal: Diabetes
Diabetes 2020;69(Supplement_1):229-OR
https://doi.org/10.2337/db20-229-OR
Published: 01 June 2020
View articletitled, 229-OR: The Gut Microbiome in Adults with Prediabetes and Effect of Dietary Glycemic Index
Meeting Abstracts

1261-P: OGTT Model–Derived ß-Cell Function Reveals Differential Loss in Youth vs. Adults during and following Treatment Withdrawal in the Restoring Insulin Secretion (RISE) Study

KRISTINA UTZSCHNEIDER, MARK TRIPPUTI, MELANIE CREE-GREEN, TAMARA S. HANNON, KRISTEN J. NADEAU, ELENA BARENGOLTS, JERRY P. PALMER, KIEREN J. MATHER, SONIA CAPRIO, SHARON EDELSTEIN, ANDREA MARI, THE RISE CONSORTIUM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1261-P
https://doi.org/10.2337/db20-1261-P
Published: 01 June 2020
View articletitled, 1261-P: OGTT Model–Derived ß-Cell Function Reveals Differential Loss in Youth vs. Adults during and following Treatment Withdrawal in the Restoring Insulin Secretion (RISE) Study
Meeting Abstracts

124-OR: Comparison of OGTT Model-Derived Measures of ß-Cell Function between Youth and Adults

KRISTINA UTZSCHNEIDER, ANDREA MARI, MARK TRIPPUTI, KIEREN J. MATHER, KRISTEN J. NADEAU, SHARON EDELSTEIN, TAMARA S. HANNON, SILVA A. ARSLANIAN, MELANIE CREE-GREEN, THOMAS A. BUCHANAN, SONIA CAPRIO, STEVEN E. KAHN, RISE CONSORTIUM
Journal: Diabetes
Diabetes 2019;68(Supplement_1):124-OR
https://doi.org/10.2337/db19-124-OR
Published: 01 June 2019
View articletitled, 124-OR: Comparison of OGTT Model-Derived Measures of ß-Cell Function between Youth and Adults
Meeting Abstracts

973-P: The Feasibility of Continuous Glucose Monitoring in Youth with Type 2 Diabetes Mellitus: A Pilot Study

ALLISON LAROCHE, KRISTINA UTZSCHNEIDER, CATHERINE PIHOKER
Journal: Diabetes
Diabetes 2019;68(Supplement_1):973-P
https://doi.org/10.2337/db19-973-P
Published: 01 June 2019
View articletitled, 973-P: The Feasibility of Continuous Glucose Monitoring in Youth with Type 2 Diabetes Mellitus: A Pilot Study
Meeting Abstracts

1832-P: Impact of Habitual Daily Activity on Glucose Tolerance (GT) and ß-Cell Function in Adults with Impaired GT (IGT) or Type 2 Diabetes (T2D)

KARLA A. TEMPLE, ASHLEY H. TJADEN, KAREN M. ATKINSON, ELENA BARENGOLTS, TAMARA S. HANNON, KIEREN J. MATHER, KRISTINA UTZSCHNEIDER, DAVID A. EHRMANN, BABAK MOKHLESI, RISE CONSORTIUM
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1832-P
https://doi.org/10.2337/db19-1832-P
Published: 01 June 2019
View articletitled, 1832-P: Impact of Habitual Daily Activity on Glucose Tolerance (GT) and ß-Cell Function in Adults with Impaired GT (IGT) or Type 2 Diabetes (T2D)
Meeting Abstracts

1826-P: Comparison of OGTT-Model Measures with the Hyperglycemic Clamp in Youth and Adults with IGT or Early Type 2 Diabetes (DM)

KRISTINA UTZSCHNEIDER, ANDREA MARI, MARK TRIPPUTI, KIEREN J. MATHER, KRISTEN J. NADEAU, SHARON EDELSTEIN, TAMARA S. HANNON, SILVA A. ARSLANIAN, MELANIE CREE-GREEN, THOMAS A. BUCHANAN, SONIA CAPRIO, STEVEN E. KAHN, RISE CONSORTIUM
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1826-P
https://doi.org/10.2337/db19-1826-P
Published: 01 June 2019
View articletitled, 1826-P: Comparison of OGTT-Model Measures with the Hyperglycemic Clamp in Youth and Adults with IGT or Early Type 2 Diabetes (DM)
Meeting Abstracts

Relationship between Baseline Phenotype and Measures of Insulin Sensitivity and Beta-Cell Responses in the GRADE Cohort

NEDA RASOULI, ROBERT M. COHEN, RALPH A. DEFRONZO, SILVIO INZUCCHI, FARAMARZ ISMAIL-BEIGI, STEVEN E. KAHN, KRISTINA UTZSCHNEIDER, JOHN LACHIN, NAJI YOUNES, GRADE RESEARCH GROUP
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1822-P
https://doi.org/10.2337/db18-1822-P
Published: 01 July 2018
View articletitled, Relationship between Baseline Phenotype and Measures of Insulin Sensitivity and Beta-Cell Responses in the GRADE Cohort
Meeting Abstracts

Does the Shape of the OGTT Glucose Curve Reflect Metabolic Function in Individuals with Type 2 Diabetes? Baseline Data from the GRADE Cohort

KRISTINA UTZSCHNEIDER, MARY ANN BANERJI, JOSHUA I. BARZILAY, ERICA V. GONZALEZ, FARAMARZ ISMAIL-BEIGI, KIEREN J. MATHER, PHILIP RASKIN, NAJI YOUNES, STEVEN E. KAHN, GRADE RESEARCH GROUP
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1811-P
https://doi.org/10.2337/db18-1811-P
Published: 01 July 2018
View articletitled, Does the Shape of the OGTT Glucose Curve Reflect Metabolic Function in Individuals with Type 2 Diabetes? Baseline Data from the GRADE Cohort
Meeting Abstracts

Sleep Disturbances Are Associated with Poorer Glycemia and Increased Obesity in Youth at Risk for or with Early Type 2 Diabetes (T2D)

BABAK MOKHLESI, KARLA A. TEMPLE, ASHLEY N. HOGAN, SHARON EDELSTEIN, KRISTEN J. NADEAU, SUSAN SAM, TAMARA HANNON, KRISTINA UTZSCHNEIDER, ELENA BARENGOLTS, SHALINI MANCHANDA, DAVID A. EHRMANN, EVE VAN CAUTER, RISE CONSORTIUM
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1643-P
https://doi.org/10.2337/db18-1643-P
Published: 01 July 2018
View articletitled, Sleep Disturbances Are Associated with Poorer Glycemia and Increased Obesity in Youth at Risk for or with Early Type 2 Diabetes (T2D)