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Laura M. Jacobsen
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Meeting Abstracts

330-OR: Narrow Variation of Glucose Inflection Points (IPs) during Progression to Type 1 Diabetes (T1D) Stratified by Demographic and Genetic Differences in Autoantibody-Positive (Ab+) Individuals

HEBA M. ISMAIL, DAVID D. CUTHBERTSON, LAURA M. JACOBSEN, BRANDON M. NATHAN, EMILY K. SIMS, MARIA J. REDONDO, JAY SOSENKO
Journal: Diabetes
Diabetes 2024;73(Supplement_1):330-OR
https://doi.org/10.2337/db24-330-OR
Published: 14 June 2024
View articletitled, 330-OR: Narrow Variation of Glucose Inflection Points (IPs) during Progression to Type 1 Diabetes (T1D) Stratified by Demographic and Genetic Differences in Autoantibody-Positive (Ab+) Individuals
Meeting Abstracts

1293-P: Real-World Status of Autoantibody Screening and Teplizumab Administration Readiness among Centers Participating in the T1D Exchange Quality Improvement Collaborative (T1DX-QI)

CARLA DEMETERCO-BERGGREN, LAURA M. JACOBSEN, INES GUTTMANN-BAUMAN, EMMA L. OSPELT, ALLISON SMEGO, TAMARA S. HANNON, GRAZIA ALEPPO, ABHA CHOUDHARY, JENISE C. WONG, OSAGIE EBEKOZIEN, T1DX-QI COLLABORATIVE
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1293-P
https://doi.org/10.2337/db24-1293-P
Published: 14 June 2024
View articletitled, 1293-P: Real-World Status of Autoantibody Screening and Teplizumab Administration Readiness among Centers Participating in the T1D Exchange Quality Improvement Collaborative (T1DX-QI)
Meeting Abstracts

1455-P: The Oral Disposition Index (ODI) and Its Components during the Progression of Autoantibody-Positive (Ab+) Individuals to Type 1 Diabetes (T1D)

HEBA M. ISMAIL, DAVID D. CUTHBERTSON, LAURA M. JACOBSEN, MARK A. ATKINSON, INGRID LIBMAN, MARIA J. REDONDO, JAY SOSENKO
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1455-P
https://doi.org/10.2337/db24-1455-P
Published: 14 June 2024
View articletitled, 1455-P: The Oral Disposition Index (ODI) and Its Components during the Progression of Autoantibody-Positive (Ab+) Individuals to Type 1 Diabetes (T1D)
Meeting Abstracts

1460-P: Antibody+ (Ab+) Individuals with Marked Metabolic Heterogeneity at Screening Have Similar Evolution in the Progression to Type 1 Diabetes (T1D) with Converging Metabolic Status

EMILY K. SIMS, LAURA M. JACOBSEN, HEBA M. ISMAIL, MARIA J. REDONDO, BRANDON M. NATHAN, JAY SOSENKO
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1460-P
https://doi.org/10.2337/db24-1460-P
Published: 14 June 2024
View articletitled, 1460-P: Antibody+ (Ab+) Individuals with Marked Metabolic Heterogeneity at Screening Have Similar Evolution in the Progression to Type 1 Diabetes (T1D) with Converging Metabolic Status
Meeting Abstracts

1448-P: The Role of a Glucose Fraction Independent of Insulin Secretion in Predicting Hyperglycemia Endpoints in Autoantibody-Positive Individuals (Ab+I)

BRANDON M. NATHAN, DAVID D. CUTHBERTSON, HEBA M. ISMAIL, LAURA M. JACOBSEN, EMILY K. SIMS, JAY SOSENKO
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1448-P
https://doi.org/10.2337/db24-1448-P
Published: 14 June 2024
View articletitled, 1448-P: The Role of a Glucose Fraction Independent of Insulin Secretion in Predicting Hyperglycemia Endpoints in Autoantibody-Positive Individuals (Ab+I)
Meeting Abstracts

1447-P: Metabolic Heterogeneity of Antibody-Positive Individuals (Ab+I) with Impaired Glucose Tolerance (IGT) according to Glucose Fractions

BRANDON M. NATHAN, DAVID D. CUTHBERTSON, HEBA M. ISMAIL, LAURA M. JACOBSEN, EMILY K. SIMS, JAY SOSENKO
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1447-P
https://doi.org/10.2337/db24-1447-P
Published: 14 June 2024
View articletitled, 1447-P: Metabolic Heterogeneity of Antibody-Positive Individuals (Ab+I) with Impaired Glucose Tolerance (IGT) according to Glucose Fractions
Meeting Abstracts

1445-P: A Glucose Fraction Independent of Insulin Secretion in Autoantibody Positive (Ab+) Individuals

JAY SOSENKO, DAVID D. CUTHBERTSON, MARIA J. REDONDO, HEBA M. ISMAIL, EMILY K. SIMS, LAURA M. JACOBSEN, BRANDON M. NATHAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1445-P
https://doi.org/10.2337/db23-1445-P
Published: 20 June 2023
View articletitled, 1445-P: A Glucose Fraction Independent of Insulin Secretion in Autoantibody Positive (Ab+) Individuals
Meeting Abstracts

1441-P: Index60 Stratification Enhances Current Staging for Type 1 Diabetes by Identifying At-Risk Single Islet Autoantibody Positive (Ab+) Individuals

EMILY K. SIMS, DAVID D. CUTHBERTSON, EMANUELE BOSI, CARMELLA EVANS-MOLINA, MARIA J. REDONDO, BRANDON M. NATHAN, HEBA M. ISMAIL, LAURA M. JACOBSEN, JAY SOSENKO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1441-P
https://doi.org/10.2337/db23-1441-P
Published: 20 June 2023
View articletitled, 1441-P: Index60 Stratification Enhances Current Staging for Type 1 Diabetes by Identifying At-Risk Single Islet Autoantibody Positive (Ab+) Individuals
Meeting Abstracts

1440-P: Single Islet Antigen 2 Antibody–Positive (IA2A Ab+) Children Exhibit Significant Metabolic Abnormalities and 5-Year Type 1 Diabetes (T1D) Risk

EMILY K. SIMS, DAVID D. CUTHBERTSON, EMANUELE BOSI, CARMELLA EVANS-MOLINA, MARIA J. REDONDO, BRANDON M. NATHAN, HEBA M. ISMAIL, LAURA M. JACOBSEN, JAY SOSENKO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1440-P
https://doi.org/10.2337/db23-1440-P
Published: 20 June 2023
View articletitled, 1440-P: Single Islet Antigen 2 Antibody–Positive (IA2A Ab+) Children Exhibit Significant Metabolic Abnormalities and 5-Year Type 1 Diabetes (T1D) Risk
Meeting Abstracts

1041-P: Health Care Transition Practices in the T1D Exchange Quality Improvement Collaborative

FAISAL MALIK, JESSE CASES-VILLABLANCA, MARISA E. HILLIARD, SARAH LYONS, LAURA M. JACOBSEN, ALISSA J. ROBERTS, ANDREA MUCCI, SHIVANI AGARWAL, CARLA DEMETERCO-BERGGREN, GUY T. ALONSO, OSAGIE EBEKOZIEN, SARAH CORATHERS, T1DX-QI COLLABORATIVE
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1041-P
https://doi.org/10.2337/db23-1041-P
Published: 20 June 2023
View articletitled, 1041-P: Health Care Transition Practices in the T1D Exchange Quality Improvement Collaborative
Meeting Abstracts

1255-P: IA-2A Autoantibody Titers Predict Subsequent Divergence between Nonprogressors (NP) and Progressors (P) to Type 1 Diabetes with Similar Degree of Initial Metabolic Abnormality

EMILY K. SIMS, DAVID D. CUTHBERTSON, LAURA M. JACOBSEN, HEBA M. ISMAIL, BRANDON M. NATHAN, MARIA J. REDONDO, JAY SOSENKO
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1255-P
https://doi.org/10.2337/db22-1255-P
Published: 01 June 2022
View articletitled, 1255-P: IA-2A Autoantibody Titers Predict Subsequent Divergence between Nonprogressors (NP) and Progressors (P) to Type 1 Diabetes with Similar Degree of Initial Metabolic Abnormality
Meeting Abstracts

825-P: Composite Glucose and C-Peptide Endpoints Show Early Efficacy in Recent-Onset Type 1 Diabetes (T1D) Clinical Trials

LAURA M. JACOBSEN, DAVID D. CUTHBERTSON, MICHAEL J. HALLER, HEBA M. ISMAIL, EMILY K. SIMS, STEPHEN E. GITELMAN, DIANE K. WHERRETT, ANTOINETTE MORAN, MARK A. ATKINSON, ALBERTO PUGLIESE, PETER GOTTLIEB, JAY SOSENKO
Journal: Diabetes
Diabetes 2022;71(Supplement_1):825-P
https://doi.org/10.2337/db22-825-P
Published: 01 June 2022
View articletitled, 825-P: Composite Glucose and C-Peptide Endpoints Show Early Efficacy in Recent-Onset Type 1 Diabetes (T1D) Clinical Trials
Meeting Abstracts

350-OR: The Oral Disposition Index (ODI) Predicts Type 1 Diabetes (T1D) in Autoantibody-Positive (Ab+) Individuals

HEBA M. ISMAIL, DAVID D. CUTHBERTSON, MARIA J. REDONDO, LAURA M. JACOBSEN, MARK A. ATKINSON, JAY SOSENKO, DIABETES PREVENTION TRIAL TYPE 1, TYPE 1 DIABETES TRIALNET
Journal: Diabetes
Diabetes 2022;71(Supplement_1):350-OR
https://doi.org/10.2337/db22-350-OR
Published: 01 June 2022
View articletitled, 350-OR: The Oral Disposition Index (ODI) Predicts Type 1 Diabetes (T1D) in Autoantibody-Positive (Ab+) Individuals
Meeting Abstracts

11-OR: Assessments of Prediagnostic Metabolic Measures as Surrogate Endpoints for Type 1 Diabetes (T1D) Prevention Trials

EMILY K. SIMS, DAVID D. CUTHBERTSON, LAURA M. JACOBSEN, KEVAN C. HEROLD, JAY SOSENKO
Journal: Diabetes
Diabetes 2021;70(Supplement_1):11-OR
https://doi.org/10.2337/db21-11-OR
Published: 01 June 2021
View articletitled, 11-OR: Assessments of Prediagnostic Metabolic Measures as Surrogate Endpoints for Type 1 Diabetes (T1D) Prevention Trials
Meeting Abstracts

589-P: Effect of Oral Insulin (OI) on Combined Glucose and C-Peptide Endpoints in Individuals at High-Risk for Type 1 Diabetes (T1D)

LAURA M. JACOBSEN, DAVID D. CUTHBERTSON, EMILY K. SIMS, HEBA M. ISMAIL, LINDA DIMEGLIO, TAYLOR M. TRIOLO, MARIA J. REDONDO, MARKUS LUNDGREN, PETER GOTTLIEB, MARK A. ATKINSON, JEFFREY KRISCHER, DESMOND SCHATZ, JAY SOSENKO
Journal: Diabetes
Diabetes 2021;70(Supplement_1):589-P
https://doi.org/10.2337/db21-589-P
Published: 01 June 2021
View articletitled, 589-P: Effect of Oral Insulin (OI) on Combined Glucose and C-Peptide Endpoints in Individuals at High-Risk for Type 1 Diabetes (T1D)
Meeting Abstracts

621-P: The Inaccuracy of Commercial Home Hemoglobin A1c Tests

LAURA M. JACOBSEN, LAURA E. BOCCHINO, JANEY ADAMS, JOHN W. LUM, MICHAEL J. HALLER, ROY BECK
Journal: Diabetes
Diabetes 2021;70(Supplement_1):621-P
https://doi.org/10.2337/db21-621-P
Published: 01 June 2021
View articletitled, 621-P: The Inaccuracy of Commercial Home Hemoglobin A1c Tests
Journal Articles

Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes

Helmut Hiller, Dawn E. Beachy, Joseph J. Lebowitz, Stefanie Engler, Justin R. Mason, Douglas R. Miller, Irina Kusmarteva, Laura M. Jacobsen, Amanda L. Posgai, Habibeh Khoshbouei, Richard A. Oram, Desmond A. Schatz, Andrew T. Hattersley, Bernd Bodenmiller, Mark A. Atkinson, Harry S. Nick, Clive H. Wasserfall
Journal: Diabetes
Diabetes 2021;70(8):1885–1897
https://doi.org/10.2337/db21-0070
Published: 25 May 2021
View articletitled, Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes
Open the PDF for Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes in another window
Journal Articles

Low-Dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report

Andrea Lin, Jasmine A. Mack, Brittany Bruggeman, Laura M. Jacobsen, Amanda L. Posgai, Clive H. Wasserfall, Todd M. Brusko, Mark A. Atkinson, Stephen E. Gitelman, Peter A. Gottlieb, Matthew J. Gurka, Clayton E. Mathews, Desmond A. Schatz, Michael J. Haller
Journal: Diabetes
Diabetes 2021;70(5):1123–1129
https://doi.org/10.2337/db20-1103
Published: 25 February 2021
View articletitled, Low-Dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report
Open the PDF for Low-Dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report in another window
Journal Articles

How Do We Move Type 1 Diabetes Immunotherapies Forward During the Current COVID-19 Pandemic?

Michael J. Haller, Laura M. Jacobsen, Amanda L. Posgai, Desmond A. Schatz
Journal: Diabetes
Diabetes 2021;70(5):1021–1028
https://doi.org/10.2337/dbi20-0045
Published: 25 February 2021
View articletitled, How Do We Move Type 1 Diabetes Immunotherapies Forward During the Current COVID-19 Pandemic?
Open the PDF for How Do We Move Type 1 Diabetes Immunotherapies Forward During the Current COVID-19 Pandemic? in another window
Meeting Abstracts

830-P: Screening for Depressive Symptoms in Adolescent Type 2 Diabetes Point to a Need for Improvement in Clinical Processes and Resources

JENINE Y. STONE, SHELAGH A. MULVANEY, CONSTANCE A. MARA, JESSICA C. KICHLER, SHIDEH MAJIDI, KIMBERLY A. DRISCOLL, SARAH C. WESTEN, ALANA RAWLINSON, LAURA M. JACOBSEN, KOREY K. HOOD, MAUREEN MONAGHAN, REBECCA N. ADAMS
Journal: Diabetes
Diabetes 2020;69(Supplement_1):830-P
https://doi.org/10.2337/db20-830-P
Published: 01 June 2020
View articletitled, 830-P: Screening for Depressive Symptoms in Adolescent Type 2 Diabetes Point to a Need for Improvement in Clinical Processes and Resources