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Journal Articles

Integrative proteogenomic analyses provide novel interpretations of type 1 diabetes risk loci through circulating proteins

Tianyuan Lu, PhD, Despoina Manousaki, MD, PhD, Lei Sun, PhD, Andrew D. Paterson, MB, ChB

Diabetes db240380

https://doi.org/10.2337/db24-0380

Published: 06 January 2025

View article titled, Integrative proteogenomic analyses provide novel interpretations of type 1 diabetes risk loci through circulating proteins

Journal Articles

Repurposing Doxepin to Ameliorate Steatosis and Hyperglycemia by Activating FAM3A Signaling Pathway

Zhenzhen Chen, Xiangyang Liu, Yanjin Luo, Junpei Wang, Yuhong Meng, Lei Sun, Yongsheng Chang, Qinghua Cui, Jichun Yang

Diabetes 2020;69(6):1126–1139

https://doi.org/10.2337/db19-1038

Published: 20 April 2020

View article titled, Repurposing Doxepin to Ameliorate Steatosis and Hyperglycemia by Activating FAM3A Signaling Pathway

Journal Articles

Function and Mechanism of Long Noncoding RNAs in Adipocyte Biology

Lei Sun, Jiandie D. Lin

Diabetes 2019;68(5):887–896

https://doi.org/10.2337/dbi18-0009

Published: 16 April 2019

View article titled, Function and Mechanism of Long Noncoding RNAs in Adipocyte Biology

Journal Articles

Adipocyte Long-Noncoding RNA Transcriptome Analysis of Obese Mice Identified Lnc-Leptin, Which Regulates Leptin

Kinyui Alice Lo, Shiqi Huang, Arcinas Camille Esther Walet, Zhi-chun Zhang, Melvin Khee-Shing Leow, Meihui Liu, Lei Sun

Diabetes 2018;67(6):1045–1056

https://doi.org/10.2337/db17-0526

Published: 08 March 2018

View article titled, Adipocyte Long-Noncoding RNA Transcriptome Analysis of Obese Mice Identified <em>Lnc-Leptin</em>, Which Regulates Leptin

Includes: Supplementary data

Journal Articles

RNA Binding Protein Ybx2 Regulates RNA Stability During Cold-Induced Brown Fat Activation

Dan Xu, Shaohai Xu, Aung Maung Maung Kyaw, Yen Ching Lim, Sook Yoong Chia, Diana Teh Chee Siang, Juan R. Alvarez-Dominguez, Peng Chen, Melvin Khee-Shing Leow, Lei Sun

Diabetes 2017;66(12):2987–3000

https://doi.org/10.2337/db17-0655

Published: 29 September 2017

View article titled, RNA Binding Protein Ybx2 Regulates RNA Stability During Cold-Induced Brown Fat Activation

Includes: Supplementary data

Journal Articles

MicroRNAs Are Required for the Feature Maintenance and Differentiation of Brown Adipocytes

Hye-Jin Kim, Hyunjii Cho, Ryan Alexander, Heide Christine Patterson, Minxia Gu, Kinyui Alice Lo, Dan Xu, Vera J. Goh, Long N. Nguyen, Xiaoran Chai, Cher X. Huang, Jean-Paul Kovalik, Sujoy Ghosh, Mirko Trajkovski, David L. Silver, Harvey Lodish, Lei Sun

Diabetes 2014;63(12):4045–4056

https://doi.org/10.2337/db14-0466

Published: 13 November 2014

View article titled, MicroRNAs Are Required for the Feature Maintenance and Differentiation of Brown Adipocytes

Includes: Supplementary data

Journal Articles

Evidence for a Causal Relationship Between Early Exocrine Pancreatic Disease and Cystic Fibrosis–Related Diabetes: A Mendelian Randomization Study

David Soave, Melissa R. Miller, Katherine Keenan, Weili Li, Jiafen Gong, Wan Ip, Frank Accurso, Lei Sun, Johanna M. Rommens, Marci Sontag, Peter R. Durie, Lisa J. Strug

Diabetes 2014;63(6):2114–2119

https://doi.org/10.2337/db13-1464

Published: 15 May 2014

View article titled, Evidence for a Causal Relationship Between Early Exocrine Pancreatic Disease and Cystic Fibrosis–Related Diabetes: A Mendelian Randomization Study

Journal Articles

Genetic Modifiers of Cystic Fibrosis–Related Diabetes

Scott M. Blackman, Clayton W. Commander, Christopher Watson, Kristin M. Arcara, Lisa J. Strug, Jaclyn R. Stonebraker, Fred A. Wright, Johanna M. Rommens, Lei Sun, Rhonda G. Pace, Sarah A. Norris, Peter R. Durie, Mitchell L. Drumm, Michael R. Knowles, Garry R. Cutting

Diabetes 2013;62(10):3627–3635

https://doi.org/10.2337/db13-0510

Published: 17 September 2013

View article titled, Genetic Modifiers of Cystic Fibrosis–Related Diabetes

Includes: Supplementary data

Journal Articles

A Genome-Wide Association Study Identifies a Novel Major Locus for Glycemic Control in Type 1 Diabetes, as Measured by Both A1C and Glucose

Andrew D. Paterson, Daryl Waggott, Andrew P. Boright, S. Mohsen Hosseini, Enqing Shen, Marie-Pierre Sylvestre, Isidro Wong, Bhupinder Bharaj, Patricia A. Cleary, John M. Lachin, MAGIC (Meta-Analyses of Glucose and Insulin-related traits Consortium), Jennifer E. Below, Dan Nicolae, Nancy J. Cox, Angelo J. Canty, Lei Sun, Shelley B. Bull, the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group

Diabetes 2010;59(2):539–549

https://doi.org/10.2337/db09-0653

Published: 20 October 2009

View article titled, A Genome-Wide Association Study Identifies a Novel Major Locus for Glycemic Control in Type 1 Diabetes, as Measured by Both A1C and Glucose

Includes: Supplementary data

Journal Articles

Multiple Superoxide Dismutase 1/Splicing Factor Serine Alanine 15 Variants Are Associated With the Development and Progression of Diabetic Nephropathy: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Genetics Study

Diabetes 2008;57(1):218–228

https://doi.org/10.2337/db07-1059

Published: 01 January 2008

View article titled, Multiple Superoxide Dismutase 1/Splicing Factor Serine Alanine 15 Variants Are Associated With the Development and Progression of Diabetic Nephropathy: <subtitle>The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Genetics Study</subtitle>

Includes: Supplementary data

Journal Articles

Multiple Variants in Vascular Endothelial Growth Factor (VEGFA) Are Risk Factors for Time to Severe Retinopathy in Type 1 Diabetes : The DCCT/EDIC Genetics Study

Hussam Al-Kateb, Lucia Mirea, Xinlei Xie, Lei Sun, Michelle Liu, Hongtao Chen, Shelley B. Bull, Andrew P. Boright, Andrew D. Paterson, for the DCCT/EDIC Research Group

Diabetes 2007;56(8):2161–2168

https://doi.org/10.2337/db07-0376

Published: 01 August 2007

View article titled, Multiple Variants in Vascular Endothelial Growth Factor (VEGFA) Are Risk Factors for Time to Severe Retinopathy in Type 1 Diabetes : <subtitle>The DCCT/EDIC Genetics Study</subtitle>

Includes: Supplementary data

NARROW

Integrative proteogenomic analyses provide novel interpretations of type 1 diabetes risk loci through circulating proteins

Repurposing Doxepin to Ameliorate Steatosis and Hyperglycemia by Activating FAM3A Signaling Pathway

Function and Mechanism of Long Noncoding RNAs in Adipocyte Biology

Adipocyte Long-Noncoding RNA Transcriptome Analysis of Obese Mice Identified Lnc-Leptin, Which Regulates Leptin

RNA Binding Protein Ybx2 Regulates RNA Stability During Cold-Induced Brown Fat Activation

MicroRNAs Are Required for the Feature Maintenance and Differentiation of Brown Adipocytes

Evidence for a Causal Relationship Between Early Exocrine Pancreatic Disease and Cystic Fibrosis–Related Diabetes: A Mendelian Randomization Study

Genetic Modifiers of Cystic Fibrosis–Related Diabetes

A Genome-Wide Association Study Identifies a Novel Major Locus for Glycemic Control in Type 1 Diabetes, as Measured by Both A1C and Glucose

Multiple Superoxide Dismutase 1/Splicing Factor Serine Alanine 15 Variants Are Associated With the Development and Progression of Diabetic Nephropathy: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Genetics Study

Multiple Variants in Vascular Endothelial Growth Factor (VEGFA) Are Risk Factors for Time to Severe Retinopathy in Type 1 Diabetes : The DCCT/EDIC Genetics Study

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