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Lena Eliasson
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Journal Articles

Glucose Controls Glucagon Secretion by Regulating Fatty Acid Oxidation in Pancreatic α-Cells

Sarah L. Armour, Alexander Frueh, Margarita V. Chibalina, Haiqiang Dou, Lidia Argemi-Muntadas, Alexander Hamilton, Georgios Katzilieris-Petras, Peter Carmeliet, Benjamin Davies, Thomas Moritz, Lena Eliasson, Patrik Rorsman, Jakob G. Knudsen
Journal: Diabetes
Diabetes 2023;72(10):1446–1459
https://doi.org/10.2337/db23-0056
Published: 26 July 2023
View article titled, Glucose Controls Glucagon Secretion by Regulating Fatty Acid Oxidation in Pancreatic α-Cells
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Journal Articles

Human Islet MicroRNA-200c Is Elevated in Type 2 Diabetes and Targets the Transcription Factor ETV5 to Reduce Insulin Secretion

Jones K. Ofori, Alexandros Karagiannopoulos, Mototsugu Nagao, Efraim Westholm, Shaima Ramadan, Anna Wendt, Jonathan L.S. Esguerra, Lena Eliasson
Journal: Diabetes
Diabetes 2022;71(2):275–284
https://doi.org/10.2337/db21-0077
Published: 09 November 2021
View article titled, Human Islet MicroRNA-200c Is Elevated in Type 2 Diabetes and Targets the Transcription Factor ETV5 to Reduce Insulin Secretion
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Journal Articles

Differential DNA Methylation and Expression of miRNAs in Adipose Tissue From Twin Pairs Discordant for Type 2 Diabetes

Emma Nilsson, Magdalena Vavakova, Alexander Perfilyev, Johanna Säll, Per-Anders Jansson, Pernille Poulsen, Jonathan Lou S. Esguerra, Lena Eliasson, Allan Vaag, Olga Göransson, Charlotte Ling
Journal: Diabetes
Diabetes 2021;70(10):2402–2418
https://doi.org/10.2337/db20-0324
Published: 27 July 2021
View article titled, Differential DNA Methylation and Expression of miRNAs in Adipose Tissue From Twin Pairs Discordant for Type 2 Diabetes
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Journal Articles

MicroRNA Networks in Pancreatic Islet Cells: Normal Function and Type 2 Diabetes

Lena Eliasson, Jonathan L.S. Esguerra
Journal: Diabetes
Diabetes 2020;69(5):804–812
https://doi.org/10.2337/dbi19-0016
Published: 13 April 2020
View article titled, MicroRNA Networks in Pancreatic Islet Cells: Normal Function and Type 2 Diabetes
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Journal Articles

Potential Protection Against Type 2 Diabetes in Obesity Through Lower CD36 Expression and Improved Exocytosis in β-Cells

Mototsugu Nagao, Jonathan L.S. Esguerra, Akira Asai, Jones K. Ofori, Anna Edlund, Anna Wendt, Hitoshi Sugihara, Claes B. Wollheim, Shinichi Oikawa, Lena Eliasson
Journal: Diabetes
Diabetes 2020;69(6):1193–1205
https://doi.org/10.2337/db19-0944
Published: 20 March 2020
View article titled, Potential Protection Against Type 2 Diabetes in Obesity Through Lower CD36 Expression and Improved Exocytosis in β-Cells
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Journal Articles

Glucolipotoxicity Alters Insulin Secretion via Epigenetic Changes in Human Islets

Elin Hall, Josefine Jönsson, Jones K. Ofori, Petr Volkov, Alexander Perfilyev, Marloes Dekker Nitert, Lena Eliasson, Charlotte Ling, Karl Bacos
Journal: Diabetes
Diabetes 2019;68(10):1965–1974
https://doi.org/10.2337/db18-0900
Published: 16 August 2019
View article titled, Glucolipotoxicity Alters Insulin Secretion via Epigenetic Changes in Human Islets
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Includes: Supplementary data
Journal Articles

Whole-Genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis

Petr Volkov, Karl Bacos, Jones K. Ofori, Jonathan Lou S. Esguerra, Lena Eliasson, Tina Rönn, Charlotte Ling
Journal: Diabetes
Diabetes 2017;66(4):1074–1085
https://doi.org/10.2337/db16-0996
Published: 04 January 2017
View article titled, Whole-Genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis
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Includes: Supplementary data
Journal Articles

Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes

Anders H. Rosengren, Matthias Braun, Taman Mahdi, Sofia A. Andersson, Mary E. Travers, Makoto Shigeto, Enming Zhang, Peter Almgren, Claes Ladenvall, Annika S. Axelsson, Anna Edlund, Morten Gram Pedersen, Anna Jonsson, Reshma Ramracheya, Yunzhao Tang, Jonathan N. Walker, Amy Barrett, Paul R.V. Johnson, Valeriya Lyssenko, Mark I. McCarthy, Leif Groop, Albert Salehi, Anna L. Gloyn, Erik Renström, Patrik Rorsman, Lena Eliasson
Journal: Diabetes
Diabetes 2012;61(7):1726–1733
https://doi.org/10.2337/db11-1516
Published: 15 June 2012
View article titled, Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes
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Includes: Supplementary data
Journal Articles

Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

Valeriya Lyssenko, Lena Eliasson, Olga Kotova, Kasper Pilgaard, Nils Wierup, Albert Salehi, Anna Wendt, Anna Jonsson, Yang Z. De Marinis, Lisa M. Berglund, Jalal Taneera, Alexander Balhuizen, Ola Hansson, Peter Osmark, Pontus Dunér, Charlotte Brøns, Alena Stančáková, Johanna Kuusisto, Marco Bugliani, Richa Saxena, Emma Ahlqvist, Timothy J. Kieffer, Tiinamaija Tuomi, Bo Isomaa, Olle Melander, Emily Sonestedt, Marju Orho-Melander, Peter Nilsson, Sara Bonetti, Riccardo Bonadonna, Roberto Miccoli, Stefano DelPrato, Piero Marchetti, Sten Madsbad, Pernille Poulsen, Allan Vaag, Markku Laakso, Maria F. Gomez, Leif Groop
Journal: Diabetes
Diabetes 2011;60(9):2424–2433
https://doi.org/10.2337/db10-1532
Published: 20 August 2011
View article titled, Pleiotropic Effects of GIP on Islet Function Involve Osteopontin
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Includes: Supplementary data
Journal Articles

Long-Term Exposure to Glucose and Lipids Inhibits Glucose-Induced Insulin Secretion Downstream of Granule Fusion With Plasma Membrane

Charlotta S. Olofsson, Stephan Collins, Martin Bengtsson, Lena Eliasson, Albert Salehi, Kenju Shimomura, Andrei Tarasov, Cecilia Holm, Frances Ashcroft, Patrik Rorsman
Journal: Diabetes
Diabetes 2007;56(7):1888–1897
https://doi.org/10.2337/db06-1150
Published: 01 July 2007
View article titled, Long-Term Exposure to Glucose and Lipids Inhibits Glucose-Induced Insulin Secretion Downstream of Granule Fusion With Plasma Membrane
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Includes: Supplementary data
Journal Articles

Regulated Exocytosis and Kiss-and-Run of Synaptic-Like Microvesicles in INS-1 and Primary Rat β-Cells

Patrick E. MacDonald, Stefanie Obermüller, Jenny Vikman, Juris Galvanovskis, Patrik Rorsman, Lena Eliasson
Journal: Diabetes
Diabetes 2005;54(3):736–743
https://doi.org/10.2337/diabetes.54.3.736
Published: 01 March 2005
View article titled, Regulated Exocytosis and Kiss-and-Run of Synaptic-Like Microvesicles in INS-1 and Primary Rat β-Cells
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Journal Articles

A Subset of 50 Secretory Granules in Close Contact With l-Type Ca2+ Channels Accounts for First-Phase Insulin Secretion in Mouse β-Cells

Sebastian Barg, Lena Eliasson, Erik Renström, Patrik Rorsman
Journal: Diabetes
Diabetes 2002;51(suppl_1):S74–S82
https://doi.org/10.2337/diabetes.51.2007.S74
Published: 01 February 2002
View article titled, A Subset of 50 Secretory Granules in Close Contact With <sc>l</sc>-Type Ca<sup>2+</sup> Channels Accounts for First-Phase Insulin Secretion in Mouse β-Cells
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