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Journal Articles

An E115A Missense Variant in CERS2 Is Associated With Increased Sleeping Energy Expenditure and Hepatic Insulin Resistance in American Indians

Sascha Heinitz, Michael Traurig, Jonathan Krakoff, Philipp Rabe, Claudia Stäubert, Sayuko Kobes, Robert L. Hanson, Michael Stumvoll, Matthias Blüher, Clifton Bogardus, Leslie Baier, Paolo Piaggi

Diabetes 2024;73(8):1361–1371

https://doi.org/10.2337/db23-0690

Published: 22 May 2024

View articletitled, An E115A Missense Variant in CERS2 Is Associated With Increased Sleeping Energy Expenditure and Hepatic Insulin Resistance in American Indians

Meeting Abstracts

287-OR: An ABCC8 R1420H Loss-of-Function Variant Affects Insulin Secretory Function and Microvascular Disease in American Indians

ELSA VAZQUEZ ARREOLA, WILLIAM C. KNOWLER, LESLIE BAIER, ROBERT L. HANSON

Diabetes 2023;72(Supplement_1):287-OR

https://doi.org/10.2337/db23-287-OR

Published: 20 June 2023

View articletitled, 287-OR: An ABCC8 R1420H Loss-of-Function Variant Affects Insulin Secretory Function and Microvascular Disease in American Indians

Meeting Abstracts

286-OR: Using iPSC-Derived Islets to Model the Effect of an ABCC8 Arg1420His Mutation in Fetal and Adult Islets

ANUP K. NAIR, KATIYA BARKHO, MICHAEL TRAURIG, ROBERT G. NELSON, CLIFTON BOGARDUS, III, LESLIE BAIER

Diabetes 2023;72(Supplement_1):286-OR

https://doi.org/10.2337/db23-286-OR

Published: 20 June 2023

View articletitled, 286-OR: Using iPSC-Derived Islets to Model the Effect of an ABCC8 Arg1420His Mutation in Fetal and Adult Islets

Meeting Abstracts

1764-P: Assessing Gene Expression Profile and Insulin Secretion in Human Beta Cells (EndoC-BH3) under Glucose Exposure

YUNHUA L. MULLER, KIMBERLY WIEDRICH, JEFF SUTHERLAND, DARTANYON JONES, LESLIE BAIER

Diabetes 2023;72(Supplement_1):1764-P

https://doi.org/10.2337/db23-1764-P

Published: 20 June 2023

View articletitled, 1764-P: Assessing Gene Expression Profile and Insulin Secretion in Human Beta Cells (EndoC-BH3) under Glucose Exposure

Meeting Abstracts

1476-P: Genetic Relationships between Puberty Onset and Type 2 Diabetes

MARIA J. RAMIREZ-LUZURIAGA, SAYUKO KOBES, LAUREN E. WEDEKIND, WEN-CHI HSUEH, LESLIE BAIER, ROBERT L. HANSON

Diabetes 2023;72(Supplement_1):1476-P

https://doi.org/10.2337/db23-1476-P

Published: 20 June 2023

View articletitled, 1476-P: Genetic Relationships between Puberty Onset and Type 2 Diabetes

Meeting Abstracts

141-OR: Associations between Type 2 Diabetes Partitioned/Process-Specific Polygenic Scores and Metabolic Traits

LAUREN E. WEDEKIND, WEN-CHI HSUEH, SAYUKO KOBES, LESLIE BAIER, CLIFTON BOGARDUS, III, WILLIAM C. KNOWLER, ANUBHA MAHAJAN, MARK MCCARTHY, ROBERT L. HANSON

Diabetes 2022;71(Supplement_1):141-OR

https://doi.org/10.2337/db22-141-OR

Published: 01 June 2022

View articletitled, 141-OR: Associations between Type 2 Diabetes Partitioned/Process-Specific Polygenic Scores and Metabolic Traits

Meeting Abstracts

301-OR: Modeling the Type 2 Diabetes–Associated ABCC8 Arg1420 His Mutation using iPSC–Derived Pancreatic Islet-Like Cells

ANUP K. NAIR, MICHAEL TRAURIG, JEFF SUTHERLAND, ROBERT G. NELSON, CLIFTON BOGARDUS, III, LESLIE BAIER

Diabetes 2022;71(Supplement_1):301-OR

https://doi.org/10.2337/db22-301-OR

Published: 01 June 2022

View articletitled, 301-OR: Modeling the Type 2 Diabetes–Associated ABCC8 Arg1420 His Mutation using iPSC–Derived Pancreatic Islet-Like Cells

Meeting Abstracts

1132-P: Genetic Relationships between Birth Weight and Type 2 Diabetes

LAUREN E. WEDEKIND, WEN-CHI HSUEH, MUIDEEN OLAIYA, SAYUKO KOBES, LESLIE BAIER, WILLIAM C. KNOWLER, ANUBHA MAHAJAN, MARK MCCARTHY, ROBERT L. HANSON

Diabetes 2021;70(Supplement_1):1132-P

https://doi.org/10.2337/db21-1132-P

Published: 01 June 2021

View articletitled, 1132-P: Genetic Relationships between Birth Weight and Type 2 Diabetes

Meeting Abstracts

1642-P: Colocalization Analyses of Genetic Associations of Type 2 Diabetes with DNA Methylation on Chromosome 11p in American Indians

ROBERT L. HANSON, SAYUKO KOBES, WEN-CHI HSUEH, YUNHUA L. MULLER, WILLIAM C. KNOWLER, LESLIE BAIER

Diabetes 2020;69(Supplement_1):1642-P

https://doi.org/10.2337/db20-1642-P

Published: 01 June 2020

View articletitled, 1642-P: Colocalization Analyses of Genetic Associations of Type 2 Diabetes with DNA Methylation on Chromosome 11p in American Indians

Meeting Abstracts

1460-P: Type 2 Diabetes Polygenic Score in Addition to Clinical Factors for Prediction of Diabetes Incidence in an Indigenous American Population

LAUREN E. WEDEKIND, SAYUKO KOBES, WEN-CHI HSUEH, LESLIE BAIER, WILLIAM C. KNOWLER, ANUBHA MAHAJAN, MARK I. MCCARTHY, ROBERT L. HANSON

Diabetes 2020;69(Supplement_1):1460-P

https://doi.org/10.2337/db20-1460-P

Published: 01 June 2020

View articletitled, 1460-P: Type 2 Diabetes Polygenic Score in Addition to Clinical Factors for Prediction of Diabetes Incidence in an Indigenous American Population

Meeting Abstracts

1977-P: Whole-Exome Sequencing Followed by Functional Analysis to Identify Variants That May Influence Body Mass Index (BMI) via a Role in Adipogenesis

YUNHUA L. MULLER, SAMANTHA E. DAY, CIGDEM KOROGLU, SAYUKO KOBES, ROBERT L. HANSON, WILLIAM C. KNOWLER, HYE IN KIM, CRISTOPHER VAN HOUT, NEHAL GOSALIA, ALAN R. SHULDINER, CLIFTON BOGARDUS, III, LESLIE BAIER

Diabetes 2020;69(Supplement_1):1977-P

https://doi.org/10.2337/db20-1977-P

Published: 01 June 2020

View articletitled, 1977-P: Whole-Exome Sequencing Followed by Functional Analysis to Identify Variants That May Influence Body Mass Index (BMI) via a Role in Adipogenesis

Meeting Abstracts

2018-P: Whole-Genome Sequence Identifies Potentially Functional Variants in Cytochrome B5 Type A (CYB5A) that Associate with Obesity in Southwest American Indians

SAMANTHA E. DAY, MICHAEL TRAURIG, PAOLO PIAGGI, PANKAJ KUMAR, SAYUKO KOBES, ROBERT L. HANSON, CLIFTON BOGARDUS, III, LESLIE BAIER

Diabetes 2020;69(Supplement_1):2018-P

https://doi.org/10.2337/db20-2018-P

Published: 01 June 2020

View articletitled, 2018-P: Whole-Genome Sequence Identifies Potentially Functional Variants in Cytochrome B5 Type A (CYB5A) that Associate with Obesity in Southwest American Indians

Meeting Abstracts

Genome-Wide Association Study of Inflammatory Cytokines in Southwestern Native Americans Identifies Novel Association between WWOX and Serum TNF-? Levels

LAUREN E. WEDEKIND, MARY WALTER, SAYUKO KOBES, PENG CHEN, WEN-CHI HSUEH, ROBERT NELSON, LESLIE BAIER, WILLIAM C. KNOWLER, ROBERT L. HANSON

Diabetes 2018;67(Supplement_1):1713-P

https://doi.org/10.2337/db18-1713-P

Published: 01 July 2018

View articletitled, Genome-Wide Association Study of Inflammatory Cytokines in Southwestern Native Americans Identifies Novel Association between WWOX and Serum TNF-? Levels

Meeting Abstracts

Association of CREBRF Variants with BMI and Diabetes in Pacific Islanders

ROBERT L. HANSON, SAIED SAFABAKHSH, JEFFREY CURTIS, DARIN K. MAHKEE, LESLIE BAIER, WILLIAM C. KNOWLER, ROBERT NELSON, WEN-CHI HSUEH

Diabetes 2018;67(Supplement_1):1719-P

https://doi.org/10.2337/db18-1719-P

Published: 01 July 2018

View articletitled, Association of CREBRF Variants with BMI and Diabetes in Pacific Islanders

Meeting Abstracts

A Low-Frequency Amerindian Specific Variant in PALD1, a Negative Regulator of Insulin Signaling, Associates with Type 2 Diabetes

ANUP K. NAIR, JEFF R. SUTHERLAND, GREGORY R. ELSON, PAOLO PIAGGI, SAYUKO KOBES, ROBERT L. HANSON, CLIFTON BOGARDUS, III, LESLIE BAIER

Diabetes 2018;67(Supplement_1):213-LB

https://doi.org/10.2337/db18-213-LB

Published: 01 July 2018

View articletitled, A Low-Frequency Amerindian Specific Variant in PALD1, a Negative Regulator of Insulin Signaling, Associates with Type 2 Diabetes

Journal Articles

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

Andrew R. Wood, Anna Jonsson, Anne U. Jackson, Nan Wang, Nienke van Leewen, Nicholette D. Palmer, Sayuko Kobes, Joris Deelen, Lorena Boquete-Vilarino, Jussi Paananen, Alena Stančáková, Dorret I. Boomsma, Eco J.C. de Geus, Elisabeth M.W. Eekhoff, Andreas Fritsche, Mark Kramer, Giel Nijpels, Annemarie Simonis-Bik, Timon W. van Haeften, Anubha Mahajan, Michael Boehnke, Richard N. Bergman, Jaakko Tuomilehto, Francis S. Collins, Karen L. Mohlke, Karina Banasik, Christopher J. Groves, Mark I. McCarthy, Diabetes Research on Patient Stratification (DIRECT), Ewan R. Pearson, Andrea Natali, Andrea Mari, Thomas A. Buchanan, Kent D. Taylor, Anny H. Xiang, Anette P. Gjesing, Niels Grarup, Hans Eiberg, Oluf Pedersen, Yii-Derr Chen, Markku Laakso, Jill M. Norris, Ulf Smith, Lynne E. Wagenknecht, Leslie Baier, Donald W. Bowden, Torben Hansen, Mark Walker, Richard M. Watanabe, Leen M. ‘t Hart, Robert L. Hanson, Timothy M. Frayling

Diabetes 2017;66(8):2296–2309

https://doi.org/10.2337/db16-1452

Published: 10 May 2017

View articletitled, A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

Includes: Supplementary data

Journal Articles

Linkage Disequilibrium Mapping of the Replicated Type 2 Diabetes Linkage Signal on Chromosome 1q

Diabetes 2009;58(7):1704–1709

https://doi.org/10.2337/db09-0081

Published: 23 April 2009

View articletitled, Linkage Disequilibrium Mapping of the Replicated Type 2 Diabetes Linkage Signal on Chromosome 1q

Includes: Supplementary data

Journal Articles

A Gly482Ser Missense Mutation in the Peroxisome Proliferator-Activated Receptor γ Coactivator-1 Is Associated With Altered Lipid Oxidation and Early Insulin Secretion in Pima Indians

Yunhua Li Muller, Clifton Bogardus, Oluf Pedersen, Leslie Baier

Diabetes 2003;52(3):895–898

https://doi.org/10.2337/diabetes.52.3.895

Published: 01 March 2003

View articletitled, A Gly482Ser Missense Mutation in the Peroxisome Proliferator-Activated Receptor γ Coactivator-1 Is Associated With Altered Lipid Oxidation and Early Insulin Secretion in Pima Indians

Journal Articles

A Ser311Cys Mutation in the Human Dopamine Receptor D2 Gene Is Associated With Reduced Energy Expenditure

P. Antonio Tataranni, Leslie Baier, Chris Jenkinson, Inge Harper, Angelo Del Parigi, Clifton Bogardus

Diabetes 2001;50(4):901–904

https://doi.org/10.2337/diabetes.50.4.901

Published: 01 April 2001

View articletitled, A Ser311Cys Mutation in the Human Dopamine Receptor D2 Gene Is Associated With Reduced Energy Expenditure

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An E115A Missense Variant in CERS2 Is Associated With Increased Sleeping Energy Expenditure and Hepatic Insulin Resistance in American Indians

287-OR: An ABCC8 R1420H Loss-of-Function Variant Affects Insulin Secretory Function and Microvascular Disease in American Indians

286-OR: Using iPSC-Derived Islets to Model the Effect of an ABCC8 Arg1420His Mutation in Fetal and Adult Islets

1764-P: Assessing Gene Expression Profile and Insulin Secretion in Human Beta Cells (EndoC-BH3) under Glucose Exposure

1476-P: Genetic Relationships between Puberty Onset and Type 2 Diabetes

141-OR: Associations between Type 2 Diabetes Partitioned/Process-Specific Polygenic Scores and Metabolic Traits

301-OR: Modeling the Type 2 Diabetes–Associated ABCC8 Arg1420 His Mutation using iPSC–Derived Pancreatic Islet-Like Cells

1132-P: Genetic Relationships between Birth Weight and Type 2 Diabetes

1642-P: Colocalization Analyses of Genetic Associations of Type 2 Diabetes with DNA Methylation on Chromosome 11p in American Indians

1460-P: Type 2 Diabetes Polygenic Score in Addition to Clinical Factors for Prediction of Diabetes Incidence in an Indigenous American Population

1977-P: Whole-Exome Sequencing Followed by Functional Analysis to Identify Variants That May Influence Body Mass Index (BMI) via a Role in Adipogenesis

2018-P: Whole-Genome Sequence Identifies Potentially Functional Variants in Cytochrome B5 Type A (CYB5A) that Associate with Obesity in Southwest American Indians

Genome-Wide Association Study of Inflammatory Cytokines in Southwestern Native Americans Identifies Novel Association between WWOX and Serum TNF-? Levels

Association of CREBRF Variants with BMI and Diabetes in Pacific Islanders

A Low-Frequency Amerindian Specific Variant in PALD1, a Negative Regulator of Insulin Signaling, Associates with Type 2 Diabetes

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

Linkage Disequilibrium Mapping of the Replicated Type 2 Diabetes Linkage Signal on Chromosome 1q

A Gly482Ser Missense Mutation in the Peroxisome Proliferator-Activated Receptor γ Coactivator-1 Is Associated With Altered Lipid Oxidation and Early Insulin Secretion in Pima Indians

A Ser311Cys Mutation in the Human Dopamine Receptor D2 Gene Is Associated With Reduced Energy Expenditure

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