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Journal Articles

Renal Tubule–Specific Angiotensinogen Deletion Attenuates SGLT2 Expression and Ameliorates Diabetic Kidney Disease in Murine Models of Type 1 Diabetes

Wen-Xia Yang, Ke Su, Min-Chun Liao, Jing Zhou, Junzheng Peng, Marie-Josée Hébert, Daniel N. Leal, Michifumi Yamashita, Kana N. Miyata, Janos G. Filep, Julie R. Ingelfinger, Shao-Ling Zhang, John S.D. Chan
Journal: Diabetes
Diabetes 2025;74(4):554–568
https://doi.org/10.2337/db24-0553
Published: 03 January 2025
View articletitled, Renal Tubule–Specific Angiotensinogen Deletion Attenuates SGLT2 Expression and Ameliorates Diabetic Kidney Disease in Murine Models of Type 1 Diabetes
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Journal Articles

Additional Evidence for the Relationship Between Type 2 Diabetes and Stroke Through Observational and Genetic Analyses

Wenqiang Zhang, Li Zhang, Jingwei Zhu, Chenghan Xiao, Huijie Cui, Chao Yang, Peijing Yan, Mingshuang Tang, Yutong Wang, Lin Chen, Yunjie Liu, Yanqiu Zou, Xueyao Wu, Ling Zhang, Chunxia Yang, Yuqin Yao, Jiayuan Li, Zhenmi Liu, Xia Jiang, Ben Zhang
Journal: Diabetes
Diabetes 2023;72(11):1671–1681
https://doi.org/10.2337/db22-0954
Published: 08 August 2023
View articletitled, Additional Evidence for the Relationship Between Type 2 Diabetes and Stroke Through Observational and Genetic Analyses
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Journal Articles

Overexpression of Nrf2 in Renal Proximal Tubular Cells Stimulates Sodium–Glucose Cotransporter 2 Expression and Exacerbates Dysglycemia and Kidney Injury in Diabetic Mice

Shuiling Zhao, Chao-Sheng Lo, Kana N. Miyata, Anindya Ghosh, Xin-Ping Zhao, Isabelle Chenier, Jean-Francois Cailhier, Jean Ethier, Jean-Baptiste Lattouf, Janos G. Filep, Julie R. Ingelfinger, Shao-Ling Zhang, John S.D. Chan
Journal: Diabetes
Diabetes 2021;70(6):1388–1403
https://doi.org/10.2337/db20-1126
Published: 05 March 2021
View articletitled, Overexpression of Nrf2 in Renal Proximal Tubular Cells Stimulates Sodium–Glucose Cotransporter 2 Expression and Exacerbates Dysglycemia and Kidney Injury in Diabetic Mice
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Journal Articles

Branched-Chain Amino Acids Exacerbate Obesity-Related Hepatic Glucose and Lipid Metabolic Disorders via Attenuating Akt2 Signaling

Huishou Zhao, Fuyang Zhang, Dan Sun, Xiong Wang, Xiaomeng Zhang, Jinglong Zhang, Feng Yan, Chong Huang, Huaning Xie, Chen Lin, Yi Liu, Miaomiao Fan, Wenjun Yan, Youhu Chen, Kun Lian, Yueyang Li, Ling Zhang, Shan Wang, Ling Tao
Journal: Diabetes
Diabetes 2020;69(6):1164–1177
https://doi.org/10.2337/db19-0920
Published: 17 March 2020
View articletitled, Branched-Chain Amino Acids Exacerbate Obesity-Related Hepatic Glucose and Lipid Metabolic Disorders via Attenuating Akt2 Signaling
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Journal Articles

Heterogeneous Nuclear Ribonucleoprotein F Stimulates Sirtuin-1 Gene Expression and Attenuates Nephropathy Progression in Diabetic Mice

Chao-Sheng Lo, Yixuan Shi, Isabelle Chenier, Anindya Ghosh, Chin-Han Wu, Jean-Francois Cailhier, Jean Ethier, Jean-Baptiste Lattouf, Janos G. Filep, Julie R. Ingelfinger, Shao-Ling Zhang, John S.D. Chan
Journal: Diabetes
Diabetes 2017;66(7):1964–1978
https://doi.org/10.2337/db16-1588
Published: 19 April 2017
View articletitled, Heterogeneous Nuclear Ribonucleoprotein F Stimulates Sirtuin-1 Gene Expression and Attenuates Nephropathy Progression in Diabetic Mice
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Includes: Supplementary data
Journal Articles

Catalase Overexpression Prevents Nuclear Factor Erythroid 2–Related Factor 2 Stimulation of Renal Angiotensinogen Gene Expression, Hypertension, and Kidney Injury in Diabetic Mice

Shaaban Abdo, Yixuan Shi, Abouzar Otoukesh, Anindya Ghosh, Chao-Sheng Lo, Isabelle Chenier, Janos G. Filep, Julie R. Ingelfinger, Shao Ling Zhang, John S.D. Chan
Journal: Diabetes
Diabetes 2014;63(10):3483–3496
https://doi.org/10.2337/db13-1830
Published: 15 September 2014
View articletitled, Catalase Overexpression Prevents Nuclear Factor Erythroid 2–Related Factor 2 Stimulation of Renal Angiotensinogen Gene Expression, Hypertension, and Kidney Injury in Diabetic Mice
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Includes: Supplementary data
Journal Articles

Adipose-Specific Knockout of Seipin/Bscl2 Results in Progressive Lipodystrophy

Lu Liu, Qingqing Jiang, Xuhong Wang, Yuxi Zhang, Ruby C.Y. Lin, Sin Man Lam, Guanghou Shui, Linkang Zhou, Peng Li, Yuhui Wang, Xin Cui, Mingming Gao, Ling Zhang, Ying Lv, Guoheng Xu, George Liu, Dong Zhao, Hongyuan Yang
Journal: Diabetes
Diabetes 2014;63(7):2320–2331
https://doi.org/10.2337/db13-0729
Published: 14 June 2014
View articletitled, Adipose-Specific Knockout of Seipin/Bscl2 Results in Progressive Lipodystrophy
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Includes: Supplementary data
Journal Articles

Catalase Prevents Maternal Diabetes–Induced Perinatal Programming via the Nrf2–HO-1 Defense System

Shiao-Ying Chang, Yun-Wen Chen, Xin-Ping Zhao, Isabelle Chenier, Stella Tran, Alexandre Sauvé, Julie R. Ingelfinger, Shao-Ling Zhang
Journal: Diabetes
Diabetes 2012;61(10):2565–2574
https://doi.org/10.2337/db12-0248
Published: 13 September 2012
View articletitled, Catalase Prevents Maternal Diabetes–Induced Perinatal Programming via the Nrf2–HO-1 Defense System
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Includes: Supplementary data
Journal Articles

Heterogeneous Nuclear Ribonucleoprotein F Suppresses Angiotensinogen Gene Expression and Attenuates Hypertension and Kidney Injury in Diabetic Mice

Chao-Sheng Lo, Shiao-Ying Chang, Isabelle Chenier, Janos G. Filep, Julie R. Ingelfinger, Shao Ling Zhang, John S.D. Chan
Journal: Diabetes
Diabetes 2012;61(10):2597–2608
https://doi.org/10.2337/db11-1349
Published: 13 September 2012
View articletitled, Heterogeneous Nuclear Ribonucleoprotein F Suppresses Angiotensinogen Gene Expression and Attenuates Hypertension and Kidney Injury in Diabetic Mice
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Includes: Supplementary data
Journal Articles

Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α (PGC-1α) Enhances Engraftment and Angiogenesis of Mesenchymal Stem Cells in Diabetic Hindlimb Ischemia

Debin Lu, Ling Zhang, Haihui Wang, Yan Zhang, Jian Liu, Jing Xu, Ziwen Liang, Wuquan Deng, Youzhao Jiang, Qinan Wu, Shufa Li, Zhihua Ai, Yuxu Zhong, Ying Ying, Hongyan Liu, Feng Gao, Zhonghui Zhang, Bing Chen
Journal: Diabetes
Diabetes 2012;61(5):1153–1159
https://doi.org/10.2337/db11-1271
Published: 13 April 2012
View articletitled, Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α (PGC-1α) Enhances Engraftment and Angiogenesis of Mesenchymal Stem Cells in Diabetic Hindlimb Ischemia
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Journal Articles

Bcl-2–Modifying Factor Induces Renal Proximal Tubular Cell Apoptosis in Diabetic Mice

Garnet J. Lau, Nicolas Godin, Hasna Maachi, Chao-Sheng Lo, Shyh-Jong Wu, Jian-Xin Zhu, Marie-Luise Brezniceanu, Isabelle Chénier, Joelle Fragasso-Marquis, Jean-Baptiste Lattouf, Jean Ethier, Janos G. Filep, Julie R. Ingelfinger, Viji Nair, Matthias Kretzler, Clemens D. Cohen, Shao-Ling Zhang, John S.D. Chan
Journal: Diabetes
Diabetes 2012;61(2):474–484
https://doi.org/10.2337/db11-0141
Published: 17 January 2012
View articletitled, Bcl-2–Modifying Factor Induces Renal Proximal Tubular Cell Apoptosis in Diabetic Mice
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Includes: Supplementary data
Journal Articles

Attenuation of Interstitial Fibrosis and Tubular Apoptosis in db/db Transgenic Mice Overexpressing Catalase in Renal Proximal Tubular Cells

Marie-Luise Brezniceanu, Fang Liu, Chih-Chang Wei, Isabelle Chénier, Nicolas Godin, Shao-Ling Zhang, Janos G. Filep, Julie R. Ingelfinger, John S.D. Chan
Journal: Diabetes
Diabetes 2008;57(2):451–459
https://doi.org/10.2337/db07-0013
Published: 01 February 2008
View articletitled, Attenuation of Interstitial Fibrosis and Tubular Apoptosis in db/db Transgenic Mice Overexpressing Catalase in Renal Proximal Tubular Cells
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