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Meeting Abstracts

331-OR: Clinical and Immunologic Features Differ in Children at Type 1 Diabetes Onset by Ethnicity

KAGAN E. KARAKUS, THEODORE FLEURY, ERIN E. BASCHAL, KRISTEN MCDANIEL, HYELIN CHOI, VANESSA LANGARICA, LIPING YU, KIMBER M. SIMMONS, AARON W. MICHELS
Journal: Diabetes
Diabetes 2024;73(Supplement_1):331-OR
https://doi.org/10.2337/db24-331-OR
Published: 14 June 2024
View article titled, 331-OR: Clinical and Immunologic Features Differ in Children at Type 1 Diabetes Onset by Ethnicity
Meeting Abstracts

397-P: The C/EBPß-XOR Axis and Genetic Risk for Diabetic Kidney Disease

UBONG EKPERIKPE, LIPING YU, ILSE S. DAEHN
Journal: Diabetes
Diabetes 2024;73(Supplement_1):397-P
https://doi.org/10.2337/db24-397-P
Published: 14 June 2024
View article titled, 397-P: The C/EBPß-XOR Axis and Genetic Risk for Diabetic Kidney Disease
Meeting Abstracts

1178-P: Autoantibodies Specifically Targeting Oxidative Post-translationally Modified Insulin in Type 1 Diabetes

XIAOFAN JIA, PAOLO POZZILLI, AHUVA NISSIM, ROCKY STROLLO, LIPING YU
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1178-P
https://doi.org/10.2337/db24-1178-P
Published: 14 June 2024
View article titled, 1178-P: Autoantibodies Specifically Targeting Oxidative Post-translationally Modified Insulin in Type 1 Diabetes
Meeting Abstracts

1292-P: Loss of Multiple Islet Autoantibody Status during Progression to Type 1 Diabetes

KIMBER M. SIMMONS, FRAN DONG, KATHLEEN WAUGH, LIPING YU, MARIAN REWERS
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1292-P
https://doi.org/10.2337/db24-1292-P
Published: 14 June 2024
View article titled, 1292-P: Loss of Multiple Islet Autoantibody Status during Progression to Type 1 Diabetes
Journal Articles

Cell-Surface ZnT8 Antibody Prevents and Reverses Autoimmune Diabetes in Mice

Devi Kasinathan, Zheng Guo, Dylan C. Sarver, G. William Wong, Shumei Yun, Aaron W. Michels, Liping Yu, Chandan Sona, Matthew N. Poy, Maria L. Golson, Dax Fu
Journal: Diabetes
Diabetes 2024;73(5):806–818
https://doi.org/10.2337/db23-0568
Published: 22 February 2024
View article titled, Cell-Surface ZnT8 Antibody Prevents and Reverses Autoimmune Diabetes in Mice
Open the PDF for Cell-Surface ZnT8 Antibody Prevents and Reverses Autoimmune Diabetes in Mice in another window
Meeting Abstracts

174-LB: Autoantibodies against PTM-IA2 Extracellular Domain Are Only Associated with Late Progression of Type 1 Diabetes

XIAOFAN JIA, JANET M. WENZLAU, MARIAN REWERS, AARON W. MICHELS, LIPING YU
Journal: Diabetes
Diabetes 2023;72(Supplement_1):174-LB
https://doi.org/10.2337/db23-174-LB
Published: 20 June 2023
View article titled, 174-LB: Autoantibodies against PTM-IA2 Extracellular Domain Are Only Associated with Late Progression of Type 1 Diabetes
Journal Articles

Cell-Surface Autoantibody Targets Zinc Transporter-8 (ZnT8) for In Vivo β-Cell Imaging and Islet-Specific Therapies

Zheng Guo, Devi Kasinathan, Chengfeng Merriman, Maki Nakayama, Hua Li, Huilin Li, Cheng Xu, G. William Wong, Liping Yu, Maria L. Golson, Dax Fu
Journal: Diabetes
Diabetes 2023;72(2):184–195
https://doi.org/10.2337/db22-0477
Published: 30 November 2022
View article titled, Cell-Surface Autoantibody Targets Zinc Transporter-8 (ZnT8) for In Vivo β-Cell Imaging and Islet-Specific Therapies
Open the PDF for Cell-Surface Autoantibody Targets Zinc Transporter-8 (ZnT8) for In Vivo β-Cell Imaging and Islet-Specific Therapies in another window
Meeting Abstracts

186-OR: Novel Autoantibodies to Deamidated IA2 Extracellular Domain in Type 1 Diabetes

XIAOFAN JIA, DONGMEI MIAO, CAIGUO ZHANG, AARON W. MICHELS, LIPING YU, JANET M. WENZLAU
Journal: Diabetes
Diabetes 2022;71(Supplement_1):186-OR
https://doi.org/10.2337/db22-186-OR
Published: 01 June 2022
View article titled, 186-OR: Novel Autoantibodies to Deamidated IA2 Extracellular Domain in Type 1 Diabetes
Meeting Abstracts

185-OR: T-Cell Receptor Repertoires during Type 1 Diabetes Development

ANGELA M. MITCHELL, ERIN E. BASCHAL, KRISTEN MCDANIEL, LAURA PYLE, KATHLEEN WAUGH, ANDREA STECK, LIPING YU, PETER GOTTLIEB, MARIAN REWERS, MAKI NAKAYAMA, AARON W. MICHELS
Journal: Diabetes
Diabetes 2022;71(Supplement_1):185-OR
https://doi.org/10.2337/db22-185-OR
Published: 01 June 2022
View article titled, 185-OR: T-Cell Receptor Repertoires during Type 1 Diabetes Development
Meeting Abstracts

1187-P: Distinct Islet Autoantibody Profiles in Hispanic Youth at Type 1 Diabetes Onset

KIMBER M. SIMMONS, TIMOTHY B. VIGERS, LAURA PYLE, ERIN M. YOUNGKIN, ERIN E. BASCHAL, KRISTEN MCDANIEL, LIPING YU, AARON W. MICHELS
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1187-P
https://doi.org/10.2337/db22-1187-P
Published: 01 June 2022
View article titled, 1187-P: Distinct Islet Autoantibody Profiles in Hispanic Youth at Type 1 Diabetes Onset
Meeting Abstracts

34-OR: SARS-CoV-2 Infection Is Not Associated with Presence of Islet Autoantibodies in Children: Autoimmunity Screening for Kids (ASK)

CRISTY GENO RASMUSSEN, XIAOFAN JIA, HANAN SHORROSH, LIPING YU, BRIGITTE I. FROHNERT, KIMBER M. SIMMONS, ANDREA STECK, LAURA PYLE, MARIAN REWERS
Journal: Diabetes
Diabetes 2022;71(Supplement_1):34-OR
https://doi.org/10.2337/db22-34-OR
Published: 01 June 2022
View article titled, 34-OR: SARS-CoV-2 Infection Is Not Associated with Presence of Islet Autoantibodies in Children: Autoimmunity Screening for Kids (ASK)
Meeting Abstracts

1119-P: Improving Clinical Utility of GAD65 Autoantibodies by Electrochemiluminescence Assay When Identifying Autoimmune Adult-Onset Diabetes

XIAOFAN JIA, YONG GU, TANWI VARTAK, DONGMEI MIAO, FRAN DONG, SAMUEL T. JERRAM, MARIAN REWERS, ASSIAMIRA FERRARA, JEAN M. LAWRENCE, LIPING YU, RICHARD D. LESLIE, THE ACTION LADA CONSORTIUM, THE DIABETES IN YOUNG ADULTS (DIYA) STUDY GROUP
Journal: Diabetes
Diabetes 2021;70(Supplement_1):1119-P
https://doi.org/10.2337/db21-1119-P
Published: 01 June 2021
View article titled, 1119-P: Improving Clinical Utility of GAD65 Autoantibodies by Electrochemiluminescence Assay When Identifying Autoimmune Adult-Onset Diabetes
Meeting Abstracts

1127-P: Expression-Based Genome-Wide Association Study Links Osteopontin and Interleukin-1 Receptor Antagonist with Type 1 Diabetes

XIAOFAN JIA, KYOKO TODA, LING HE, DONGMEI MIAO, SATORU YAMADA, LIPING YU, KEIICHI KODAMA
Journal: Diabetes
Diabetes 2021;70(Supplement_1):1127-P
https://doi.org/10.2337/db21-1127-P
Published: 01 June 2021
View article titled, 1127-P: Expression-Based Genome-Wide Association Study Links Osteopontin and Interleukin-1 Receptor Antagonist with Type 1 Diabetes
Meeting Abstracts

12-OR: Metabolic Effects of Two Oral Insulin Dosing Regimens in Individuals at High Risk for Type 1 Diabetes (T1D)

MARIA J. REDONDO, JAY SOSENKO, EMILY K. SIMS, DAVID D. CUTHBERTSON, EDDIE A. JAMES, S. ALICE LONG, WILLIAM KWOK, LIPING YU, AARON W. MICHELS, ÅKE LERNMARK, PETER GOTTLIEB
Journal: Diabetes
Diabetes 2021;70(Supplement_1):12-OR
https://doi.org/10.2337/db21-12-OR
Published: 01 June 2021
View article titled, 12-OR: Metabolic Effects of Two Oral Insulin Dosing Regimens in Individuals at High Risk for Type 1 Diabetes (T1D)
Meeting Abstracts

109-OR: T-Cell Responses to Hybrid Insulin Peptides Precede Type 1 Diabetes Development

ANGELA M. MITCHELL, AIMON ALKANANI, KRISTEN MCDANIEL, LAURA PYLE, KATHLEEN WAUGH, ANDREA STECK, MAKI NAKAYAMA, LIPING YU, PETER GOTTLIEB, MARIAN REWERS, AARON W. MICHELS
Journal: Diabetes
Diabetes 2021;70(Supplement_1):109-OR
https://doi.org/10.2337/db21-109-OR
Published: 01 June 2021
View article titled, 109-OR: T-Cell Responses to Hybrid Insulin Peptides Precede Type 1 Diabetes Development
Meeting Abstracts

74-OR: Islet Autoantibodies in Youth with Diabetes from South Asia

KIMBER SIMMONS, ERIN M. YOUNGKIN, ANGELA CONDIE, AIMON ALKANANI, KRISTEN MCDANIEL, LIPING YU, GRAHAM D. OGLE, AARON W. MICHELS
Journal: Diabetes
Diabetes 2021;70(Supplement_1):74-OR
https://doi.org/10.2337/db21-74-OR
Published: 01 June 2021
View article titled, 74-OR: Islet Autoantibodies in Youth with Diabetes from South Asia
Meeting Abstracts

182-OR: Genetic Susceptibility to Diabetic Kidney Disease Is Linked to C/EBP-XOR Axis

QIN WANG, HAIYING QI, SHUYU LI, GABRIELLA CASALENA, LIPING YU, ILSE S. DAEHN
Journal: Diabetes
Diabetes 2021;70(Supplement_1):182-OR
https://doi.org/10.2337/db21-182-OR
Published: 01 June 2021
View article titled, 182-OR: Genetic Susceptibility to Diabetic Kidney Disease Is Linked to C/EBP-XOR Axis
Meeting Abstracts

159-LB: High-Affinity ZnT8 Autoantibodies by Electrochemiluminescence Assay Improve the Risk Prediction for Type 1 Diabetes

XIAOFAN JIA, LING HE, DONGMEI MIAO, KATHLEEN WAUGH, CRISTY GENO RASMUSSEN, FRAN DONG, MARIAN REWERS, LIPING YU
Journal: Diabetes
Diabetes 2021;70(Supplement_1):159-LB
https://doi.org/10.2337/db21-159-LB
Published: 01 June 2021
View article titled, 159-LB: High-Affinity ZnT8 Autoantibodies by Electrochemiluminescence Assay Improve the Risk Prediction for Type 1 Diabetes
Meeting Abstracts

158-LB: A Complete-Panel Islet Autoantibody Multiplex ECL Assay

LING HE, XIAOFAN JIA, DONGMEI MIAO, CRISTY GENO RASMUSSEN, MARIAN REWERS, LIPING YU
Journal: Diabetes
Diabetes 2021;70(Supplement_1):158-LB
https://doi.org/10.2337/db21-158-LB
Published: 01 June 2021
View article titled, 158-LB: A Complete-Panel Islet Autoantibody Multiplex ECL Assay
Journal Articles

Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms

Natasha C. Ward, Jen Bon Lui, Rosmely Hernandez, Liping Yu, Mary Struthers, Jenny Xie, Alicia Santos Savio, Connor J. Dwyer, Sunnie Hsiung, Aixin Yu, Thomas R. Malek
Journal: Diabetes
Diabetes 2020;69(11):2400–2413
https://doi.org/10.2337/db20-0186
Published: 25 August 2020
View article titled, Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms
Open the PDF for Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms in another window