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Lisa C. Heather
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Journal Articles

Redefining Diabetic Cardiomyopathy: Perturbations in Substrate Metabolism at the Heart of Its Pathology

Lisa C. Heather, Keshav Gopal, Nikola Srnic, John R. Ussher
Journal: Diabetes
Diabetes 2024;73(5):659–670
https://doi.org/10.2337/dbi23-0019
Published: 22 February 2024
View article titled, Redefining Diabetic Cardiomyopathy: Perturbations in Substrate Metabolism at the Heart of Its Pathology
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Journal Articles

Activation of HIF1α Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart

Maria da Luz Sousa Fialho, Ujang Purnama, Kaitlyn M.J.H. Dennis, Claudia N. Montes Aparicio, Marcos Castro-Guarda, Emmanuelle Massourides, Damian J. Tyler, Carolyn A. Carr, Lisa C. Heather
Journal: Diabetes
Diabetes 2021;70(11):2518–2531
https://doi.org/10.2337/db21-0398
Published: 15 September 2021
View article titled, Activation of HIF1α Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart
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Journal Articles

Assessment of Metformin-Induced Changes in Cardiac and Hepatic Redox State Using Hyperpolarized[1-13C]Pyruvate

Andrew J.M. Lewis, Jack J.J. Miller, Chloe McCallum, Oliver J. Rider, Stefan Neubauer, Lisa C. Heather, Damian J. Tyler
Journal: Diabetes
Diabetes 2016;65(12):3544–3551
https://doi.org/10.2337/db16-0804
Published: 25 August 2016
View article titled, Assessment of Metformin-Induced Changes in Cardiac and Hepatic Redox State Using Hyperpolarized[1-<sup>13</sup>C]Pyruvate
Open the PDF for Assessment of Metformin-Induced Changes in Cardiac and Hepatic Redox State Using Hyperpolarized[1-<sup>13</sup>C]Pyruvate in another window
Includes: Supplementary data
Journal Articles

Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined 13C Hyperpolarized Magnetic Resonance and Echocardiography Study

Lydia M. Le Page, Oliver J. Rider, Andrew J. Lewis, Vicky Ball, Kieran Clarke, Edvin Johansson, Carolyn A. Carr, Lisa C. Heather, Damian J. Tyler
Journal: Diabetes
Diabetes 2015;64(8):2735–2743
https://doi.org/10.2337/db14-1560
Published: 20 March 2015
View article titled, Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined <sup>13</sup>C Hyperpolarized Magnetic Resonance and Echocardiography Study
Open the PDF for Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined <sup>13</sup>C Hyperpolarized Magnetic Resonance and Echocardiography Study in another window