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Liyan Zhang
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Meeting Abstracts

207-LB: Aldose Reductase Inhibition by AT-001 Limits Diastolic Dysfunction and Adverse Remodelling in Diabetic Cardiomyopathy

QUTUBA G. KARWI, KESHAV GOPAL, SEYED AMIRHOSSEIN TABATABAEI DAKHILI, CORY S. WAGG, LIYAN ZHANG, QIUYU SUN, CHRISTINA T. SAED, SAI PANIDARAPU, RICCARDO PERFETTI, RAVICHANDRAN RAMASAMY, JOHN R. USSHER, GARY LOPASCHUK
Journal: Diabetes
Diabetes 2022;71(Supplement_1):207-LB
https://doi.org/10.2337/db22-207-LB
Published: 01 June 2022
View article titled, 207-LB: Aldose Reductase Inhibition by AT-001 Limits Diastolic Dysfunction and Adverse Remodelling in Diabetic Cardiomyopathy
Journal Articles

Genetic and Pharmacological Inhibition of Malonyl CoA Decarboxylase Does Not Exacerbate Age-Related Insulin Resistance in Mice

John R. Ussher, Natasha Fillmore, Wendy Keung, Liyan Zhang, Jun Mori, Vaninder K. Sidhu, Arata Fukushima, Keshav Gopal, David G. Lopaschuk, Cory S. Wagg, Jagdip S. Jaswal, Jason R.B. Dyck, Gary D. Lopaschuk
Journal: Diabetes
Diabetes 2016;65(7):1883–1891
https://doi.org/10.2337/db15-1145
Published: 13 May 2016
View article titled, Genetic and Pharmacological Inhibition of Malonyl CoA Decarboxylase Does Not Exacerbate Age-Related Insulin Resistance in Mice
Open the PDF for Genetic and Pharmacological Inhibition of Malonyl CoA Decarboxylase Does Not Exacerbate Age-Related Insulin Resistance in Mice in another window
Includes: Supplementary data
Journal Articles

Lowering Body Weight in Obese Mice With Diastolic Heart Failure Improves Cardiac Insulin Sensitivity and Function: Implications for the Obesity Paradox

Sowndramalingam Sankaralingam, Osama Abo Alrob, Liyan Zhang, Jagdip S. Jaswal, Cory S. Wagg, Arata Fukushima, Raj S. Padwal, David E. Johnstone, Arya M. Sharma, Gary D. Lopaschuk
Journal: Diabetes
Diabetes 2015;64(5):1643–1657
https://doi.org/10.2337/db14-1050
Published: 18 December 2014
View article titled, Lowering Body Weight in Obese Mice With Diastolic Heart Failure Improves Cardiac Insulin Sensitivity and Function: Implications for the Obesity Paradox
Open the PDF for Lowering Body Weight in Obese Mice With Diastolic Heart Failure Improves Cardiac Insulin Sensitivity and Function: Implications for the Obesity Paradox in another window
Includes: Supplementary data
Journal Articles

Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption

John R. Ussher, Timothy R. Koves, Virgilio J.J. Cadete, Liyan Zhang, Jagdip S. Jaswal, Suzanne J. Swyrd, David G. Lopaschuk, Spencer D. Proctor, Wendy Keung, Deborah M. Muoio, Gary D. Lopaschuk
Journal: Diabetes
Diabetes 2010;59(10):2453–2464
https://doi.org/10.2337/db09-1293
Published: 03 June 2010
View article titled, Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption
Open the PDF for Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption in another window
Includes: Supplementary data
Journal Articles

Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase

John R. Ussher, Timothy R. Koves, Jagdip S. Jaswal, Liyan Zhang, Olga Ilkayeva, Jason R.B. Dyck, Deborah M. Muoio, Gary D. Lopaschuk
Journal: Diabetes
Diabetes 2009;58(8):1766–1775
https://doi.org/10.2337/db09-0011
Published: 28 May 2009
View article titled, Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase
Open the PDF for Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase in another window
Includes: Supplementary data