1-20 of 23
Lorenzo Piemonti
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional WFS1 variant

Silvia Torchio, Gabriel Siracusano, Federica Cuozzo, Valentina Zamarian, Silvia Pellegrini, Fabio Manenti, Riccardo Bonfanti, Giulio Frontino, Valeria Sordi, Raniero Chimienti, Lorenzo Piemonti
Journal: Diabetes
Diabetes db240720
https://doi.org/10.2337/db24-0720
Published: 09 April 2025
View articletitled, Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional WFS1 variant
Open the PDF for Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional WFS1 variant in another window
Journal Articles

Improved Specificity of Glutamate Decarboxylase 65 Autoantibody Measurement Using Luciferase-Based Immunoprecipitation System Assays

Rebecca C. Wyatt, Sian L. Grace, Cristina Brigatti, Ilaria Marzinotto, Ben T. Gillard, Deborah K. Shoemark, Kyla Chandler, Peter Achenbach, Lorenzo Piemonti, Anna E. Long, Kathleen M. Gillespie, Vito Lampasona, Alistair J.K. Williams, BOX Study Group, Isabel Wilson, Rachel Aitken, Ilana Kelland, Clare Megson, Chitrabhanu Ballav, Atanu Dutta, Michelle Russell-Taylor, Rachel Besser, James Bursell, Shanthi Chandran, Sejal Patel, Anne Smith, Manohara Kenchaiah, Gomathi Margabanthu, Foteini Kavvoura, Chandan Yaliwal
Journal: Diabetes
Diabetes 2024;73(4):565–571
https://doi.org/10.2337/db23-0550
Published: 17 January 2024
View articletitled, Improved Specificity of Glutamate Decarboxylase 65 Autoantibody Measurement Using Luciferase-Based Immunoprecipitation System Assays
Open the PDF for Improved Specificity of Glutamate Decarboxylase 65 Autoantibody Measurement Using Luciferase-Based Immunoprecipitation System Assays in another window
Meeting Abstracts

78-OR: LRH-1/NR5A2 Agonism Triggers an Anti-Inflammatory Phenotypic Switch of Immune Cells from Patients with Type 1 Diabetes and Improves Islet Engraftment/Function

NADIA COBO-VUILLEUMIER, SILVIA RODRIGUEZ-FERNANDEZ, PETRA I. LORENZO, LIVIA LOPEZ, AKAITZ DORRONSORO, CHRISTIAN C. LACHAUD, LIDIA ALMENARA-FUENTES, MIREIA RAMOS-RODRÍGUEZ, ISABEL MERIDA, MANUEL AGUILAR-DIOSDADO, RITA NANO, SR., LORENZO PIEMONTI, LORENZO PASQUALI, FRANZ MARTIN, ISABEL GARCIA-SANCHEZ, MARIA ASUNCION MARTINEZ-BROCCA, MARTA VIVES-PI, BENOIT R. GAUTHIER
Journal: Diabetes
Diabetes 2022;71(Supplement_1):78-OR
https://doi.org/10.2337/db22-78-OR
Published: 01 June 2022
View articletitled, 78-OR: LRH-1/NR5A2 Agonism Triggers an Anti-Inflammatory Phenotypic Switch of Immune Cells from Patients with Type 1 Diabetes and Improves Islet Engraftment/Function
Journal Articles

Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function

Rebecca Cheung, Grazia Pizza, Pauline Chabosseau, Delphine Rolando, Alejandra Tomas, Thomas Burgoyne, Zhiyi Wu, Anna Salowka, Anusha Thapa, Annabel Macklin, Yufei Cao, Marie-Sophie Nguyen-Tu, Matthew T. Dickerson, David A. Jacobson, Piero Marchetti, James Shapiro, Lorenzo Piemonti, Eelco de Koning, Isabelle Leclerc, Karim Bouzakri, Kei Sakamoto, David M. Smith, Guy A. Rutter, Aida Martinez-Sanchez
Journal: Diabetes
Diabetes 2022;71(7):1525–1545
https://doi.org/10.2337/db21-0803
Published: 27 April 2022
View articletitled, Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function
Open the PDF for Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function in another window
Journal Articles

Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes

Andrea Vecchione, Tatiana Jofra, Jolanda Gerosa, Kimberly Shankwitz, Roberta Di Fonte, Giuseppe Galvani, Elio Ippolito, Maria Pia Cicalese, Andrew R. Schultz, Howie R. Seay, Mariagrazia Favellato, Giulia Milardi, Angela Stabilini, Francesca Ragogna, Pauline Grogan, Eleonora Bianconi, Andrea Laurenzi, Amelia Caretto, Rita Nano, Raffaela Melzi, Nichole Danzl, Emanuele Bosi, Lorenzo Piemonti, Alessandro Aiuti, Todd Brusko, Constantinos Petrovas, Manuela Battaglia, Georgia Fousteri
Journal: Diabetes
Diabetes 2021;70(12):2892–2902
https://doi.org/10.2337/db21-0091
Published: 07 October 2021
View articletitled, Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes
Open the PDF for Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes in another window
Meeting Abstracts

249-OR: A Randomized, Double-Blind Phase 2 Trial of the CXCR1/2 Inhibitor Ladarixin in Adult Patients with New-Onset Type 1 Diabetes

EMANUELE BOSI, PAOLO POZZILLI, FRANCESCO GIORGINO, EFISIO COSSU, THOMAS LINN, LUDGER ROSE, BART KEYMEULEN, SR., PIETER GILLARD, LUISA DAFFONCHIO, PIER A. RUFFINI, MARCELLO ALLEGRETTI, LORENZO PIEMONTI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):249-OR
https://doi.org/10.2337/db20-249-OR
Published: 01 June 2020
View articletitled, 249-OR: A Randomized, Double-Blind Phase 2 Trial of the CXCR1/2 Inhibitor Ladarixin in Adult Patients with New-Onset Type 1 Diabetes
Journal Articles

Islets for Research: Nothing Is Perfect, but We Can Do Better

Rita Nano, Julie A. Kerr-Conte, Domenico Bosco, Marie Karlsson, Vanessa Lavallard, Raffaella Melzi, Valery Gmyr, Alessia Mercalli, Thierry Berney, François Pattou, Olle Korsgren, Lorenzo Piemonti
Journal: Diabetes
Diabetes 2019;68(8):1541–1543
https://doi.org/10.2337/db19-0367
Published: 15 July 2019
View articletitled, Islets for Research: Nothing Is Perfect, but We Can Do Better
Open the PDF for Islets for Research: Nothing Is Perfect, but We Can Do Better in another window
Journal Articles

Detection and Characterization of CD8+ Autoreactive Memory Stem T Cells in Patients With Type 1 Diabetes

Debora Vignali, Elisa Cantarelli, Carlotta Bordignon, Adriana Canu, Antonio Citro, Andrea Annoni, Lorenzo Piemonti, Paolo Monti
Journal: Diabetes
Diabetes 2018;67(5):936–945
https://doi.org/10.2337/db17-1390
Published: 05 March 2018
View articletitled, Detection and Characterization of CD8+ Autoreactive Memory Stem T Cells in Patients With Type 1 Diabetes
Open the PDF for Detection and Characterization of CD8+ Autoreactive Memory Stem T Cells in Patients With Type 1 Diabetes in another window
Includes: Supplementary data
Journal Articles

A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells

Teresa Buenaventura, Nisha Kanda, Phoebe C. Douzenis, Ben Jones, Stephen R. Bloom, Pauline Chabosseau, Ivan R. Corrêa, Jr., Domenico Bosco, Lorenzo Piemonti, Piero Marchetti, Paul R. Johnson, A.M. James Shapiro, Guy A. Rutter, Alejandra Tomas
Journal: Diabetes
Diabetes 2018;67(3):385–399
https://doi.org/10.2337/db17-0639
Published: 28 December 2017
View articletitled, A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells
Open the PDF for A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells in another window
Includes: Supplementary data
Journal Articles

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

Nicholas H.F. Fine, Craig L. Doig, Yasir S. Elhassan, Nicholas C. Vierra, Piero Marchetti, Marco Bugliani, Rita Nano, Lorenzo Piemonti, Guy A. Rutter, David A. Jacobson, Gareth G. Lavery, David J. Hodson
Journal: Diabetes
Diabetes 2018;67(2):278–290
https://doi.org/10.2337/db16-1356
Published: 04 December 2017
View articletitled, Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion
Open the PDF for Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion in another window
Includes: Supplementary data
Journal Articles

Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity

Chiara Cianciaruso, Edward A. Phelps, Miriella Pasquier, Romain Hamelin, Davide Demurtas, Mohamed Alibashe Ahmed, Lorenzo Piemonti, Sachiko Hirosue, Melody A. Swartz, Michele De Palma, Jeffrey A. Hubbell, Steinunn Baekkeskov
Journal: Diabetes
Diabetes 2017;66(2):460–473
https://doi.org/10.2337/db16-0671
Published: 21 November 2016
View articletitled, Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity
Open the PDF for Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity in another window
Includes: Supplementary data
Journal Articles

Identification of Tetraspanin-7 as a Target of Autoantibodies in Type 1 Diabetes

Kerry A. McLaughlin, Carolyn C. Richardson, Aarthi Ravishankar, Cristina Brigatti, Daniela Liberati, Vito Lampasona, Lorenzo Piemonti, Diana Morgan, Richard G. Feltbower, Michael R. Christie
Journal: Diabetes
Diabetes 2016;65(6):1690–1698
https://doi.org/10.2337/db15-1058
Published: 07 March 2016
View articletitled, Identification of Tetraspanin-7 as a Target of Autoantibodies in Type 1 Diabetes
Open the PDF for Identification of Tetraspanin-7 as a Target of Autoantibodies in Type 1 Diabetes in another window
Includes: Supplementary data
Journal Articles

Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+ Stores

Alice Marmugi, Julia Parnis, Xi Chen, LeAnne Carmichael, Julie Hardy, Naila Mannan, Piero Marchetti, Lorenzo Piemonti, Domenico Bosco, Paul Johnson, James A.M. Shapiro, Céline Cruciani-Guglielmacci, Christophe Magnan, Mark Ibberson, Bernard Thorens, Héctor H. Valdivia, Guy A. Rutter, Isabelle Leclerc
Journal: Diabetes
Diabetes 2016;65(4):1009–1021
https://doi.org/10.2337/db15-1334
Published: 28 January 2016
View articletitled, Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+ Stores
Open the PDF for Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+ Stores in another window
Includes: Supplementary data
Journal Articles

CXCR1/2 Inhibition Blocks and Reverses Type 1 Diabetes in Mice

Antonio Citro, Andrea Valle, Elisa Cantarelli, Alessia Mercalli, Silvia Pellegrini, Daniela Liberati, Luisa Daffonchio, Olga Kastsiuchenka, Pier Adelchi Ruffini, Manuela Battaglia, Marcello Allegretti, Lorenzo Piemonti
Journal: Diabetes
Diabetes 2015;64(4):1329–1340
https://doi.org/10.2337/db14-0443
Published: 14 October 2014
View articletitled, CXCR1/2 Inhibition Blocks and Reverses Type 1 Diabetes in Mice
Open the PDF for CXCR1/2 Inhibition Blocks and Reverses Type 1 Diabetes in Mice in another window
Includes: Supplementary data
Journal Articles

ADCY5 Couples Glucose to Insulin Secretion in Human Islets

David J. Hodson, Ryan K. Mitchell, Lorella Marselli, Timothy J. Pullen, Silvia Gimeno Brias, Francesca Semplici, Katy L. Everett, Dermot M.F. Cooper, Marco Bugliani, Piero Marchetti, Vanessa Lavallard, Domenico Bosco, Lorenzo Piemonti, Paul R. Johnson, Stephen J. Hughes, Daliang Li, Wen-Hong Li, A.M. James Shapiro, Guy A. Rutter
Journal: Diabetes
Diabetes 2014;63(9):3009–3021
https://doi.org/10.2337/db13-1607
Published: 16 August 2014
View articletitled, ADCY5 Couples Glucose to Insulin Secretion in Human Islets
Open the PDF for ADCY5 Couples Glucose to Insulin Secretion in Human Islets in another window
Includes: Supplementary data
Journal Articles

RFamide Peptides 43RFa and 26RFa Both Promote Survival of Pancreatic β-Cells and Human Pancreatic Islets but Exert Opposite Effects on Insulin Secretion

Riccarda Granata, Fabio Settanni, Letizia Trovato, Davide Gallo, Iacopo Gesmundo, Rita Nano, Maria Pia Gallo, Loredana Bergandi, Marco Volante, Giuseppe Alloatti, Lorenzo Piemonti, Jérôme Leprince, Mauro Papotti, Hubert Vaudry, Huy Ong, Ezio Ghigo
Journal: Diabetes
Diabetes 2014;63(7):2380–2393
https://doi.org/10.2337/db13-1522
Published: 14 June 2014
View articletitled, RFamide Peptides 43RFa and 26RFa Both Promote Survival of Pancreatic β-Cells and Human Pancreatic Islets but Exert Opposite Effects on Insulin Secretion
Open the PDF for RFamide Peptides 43RFa and 26RFa Both Promote Survival of Pancreatic β-Cells and Human Pancreatic Islets but Exert Opposite Effects on Insulin Secretion in another window
Journal Articles

Autologous Pancreatic Islet Transplantation in Human Bone Marrow. Diabetes 2013;62: 3523–3531

Paola Maffi, Gianpaolo Balzano, Maurilio Ponzoni, Rita Nano, Valeria Sordi, Raffaella Melzi, Alessia Mercalli, Marina Scavini, Antonio Esposito, Jacopo Peccatori, Elisa Cantarelli, Carlo Messina, Massimo Bernardi, Alessandro Del Maschio, Carlo Staudacher, Claudio Doglioni, Fabio Ciceri, Antonio Secchi, Lorenzo Piemonti
Journal: Diabetes
Diabetes 2014;63(1):377
https://doi.org/10.2337/db14-er01
Published: 13 December 2013
View articletitled, Autologous Pancreatic Islet Transplantation in Human Bone Marrow. Diabetes 2013;62: 3523–3531
Open the PDF for Autologous Pancreatic Islet Transplantation in Human Bone Marrow. Diabetes 2013;62: 3523–3531 in another window
Journal Articles

Autologous Pancreatic Islet Transplantation in Human Bone Marrow

Paola Maffi, Gianpaolo Balzano, Maurilio Ponzoni, Rita Nano, Valeria Sordi, Raffaella Melzi, Alessia Mercalli, Marina Scavini, Antonio Esposito, Jacopo Peccatori, Elisa Cantarelli, Carlo Messina, Massimo Bernardi, Alessandro Del Maschio, Carlo Staudacher, Claudio Doglioni, Fabio Ciceri, Antonio Secchi, Lorenzo Piemonti
Journal: Diabetes
Diabetes 2013;62(10):3523–3531
https://doi.org/10.2337/db13-0465
Published: 17 September 2013
View articletitled, Autologous Pancreatic Islet Transplantation in Human Bone Marrow
Open the PDF for Autologous Pancreatic Islet Transplantation in Human Bone Marrow in another window
Includes: Supplementary data
Journal Articles

Reduction of Circulating Neutrophils Precedes and Accompanies Type 1 Diabetes

Andrea Valle, Gian Maria Giamporcaro, Marina Scavini, Angela Stabilini, Pauline Grogan, Eleonora Bianconi, Guido Sebastiani, Matilde Masini, Norma Maugeri, Laura Porretti, Riccardo Bonfanti, Franco Meschi, Maurizio De Pellegrin, Arianna Lesma, Silvano Rossini, Lorenzo Piemonti, Piero Marchetti, Francesco Dotta, Emanuele Bosi, Manuela Battaglia
Journal: Diabetes
Diabetes 2013;62(6):2072–2077
https://doi.org/10.2337/db12-1345
Published: 17 May 2013
View articletitled, Reduction of Circulating Neutrophils Precedes and Accompanies Type 1 Diabetes
Open the PDF for Reduction of Circulating Neutrophils Precedes and Accompanies Type 1 Diabetes in another window
Includes: Supplementary data
Journal Articles

Alloantibody and Autoantibody Monitoring Predicts Islet Transplantation Outcome in Human Type 1 Diabetes

Lorenzo Piemonti, Matthew J. Everly, Paola Maffi, Marina Scavini, Francesca Poli, Rita Nano, Massimo Cardillo, Raffaella Melzi, Alessia Mercalli, Valeria Sordi, Vito Lampasona, Alejandro Espadas de Arias, Mario Scalamogna, Emanuele Bosi, Ezio Bonifacio, Antonio Secchi, Paul I. Terasaki
Journal: Diabetes
Diabetes 2013;62(5):1656–1664
https://doi.org/10.2337/db12-1258
Published: 16 April 2013
View articletitled, Alloantibody and Autoantibody Monitoring Predicts Islet Transplantation Outcome in Human Type 1 Diabetes
Open the PDF for Alloantibody and Autoantibody Monitoring Predicts Islet Transplantation Outcome in Human Type 1 Diabetes in another window
Includes: Supplementary data