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Louise A. Donnelly
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Meeting Abstracts

364-OR: Unsupervised Approach Systematically Analyzes the Multiomics Profiles Associated with T2D Insulin Insensitivity—An IMI-RHAPSODY Study

SHIYING LI, MARK IBBERSON, GUY A. RUTTER, EWAN PEARSON, RODERICK SLIEKER, JOLINE BEULENS, MICHAEL K. HANSEN, DMITRY KUZNETSOV, MATHIAS J. GERL, IULIAN J. DRAGAN, KAI SIMONS, LOUISE A. DONNELLY, VAN DU T. TRAN, FLORENCE MEHL, LEEN M. 'T HART
Journal: Diabetes
Diabetes 2023;72(Supplement_1):364-OR
https://doi.org/10.2337/db23-364-OR
Published: 20 June 2023
View article titled, 364-OR: Unsupervised Approach Systematically Analyzes the Multiomics Profiles Associated with T2D Insulin Insensitivity—An IMI-RHAPSODY Study
Journal Articles

Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study

Roderick C. Slieker, Louise A. Donnelly, Hugo Fitipaldi, Gerard A. Bouland, Giuseppe N. Giordano, Mikael Åkerlund, Mathias J. Gerl, Emma Ahlqvist, Ashfaq Ali, Iulian Dragan, Petra Elders, Andreas Festa, Michael K. Hansen, Amber A. van der Heijden, Dina Mansour Aly, Min Kim, Dmitry Kuznetsov, Florence Mehl, Christian Klose, Kai Simons, Imre Pavo, Timothy J. Pullen, Tommi Suvitaival, Asger Wretlind, Peter Rossing, Valeriya Lyssenko, Cristina Legido Quigley, Leif Groop, Bernard Thorens, Paul W. Franks, Mark Ibberson, Guy A. Rutter, Joline W.J. Beulens, Leen M. ’t Hart, Ewan R. Pearson
Journal: Diabetes
Diabetes 2021;70(11):2683–2693
https://doi.org/10.2337/db20-1281
Published: 10 August 2021
View article titled, Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study
Open the PDF for Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study in another window
Journal Articles

Association of Organic Cation Transporter 1 With Intolerance to Metformin in Type 2 Diabetes: A GoDARTS Study

Tanja Dujic, Kaixin Zhou, Louise A. Donnelly, Roger Tavendale, Colin N.A. Palmer, Ewan R. Pearson
Journal: Diabetes
Diabetes 2015;64(5):1786–1793
https://doi.org/10.2337/db14-1388
Published: 15 December 2014
View article titled, Association of Organic Cation Transporter 1 With Intolerance to Metformin in Type 2 Diabetes: A GoDARTS Study
Open the PDF for Association of Organic Cation Transporter 1 With Intolerance to Metformin in Type 2 Diabetes: A GoDARTS Study in another window
Includes: Supplementary data
Journal Articles

The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway

Leen M. ‘t Hart, Andreas Fritsche, Giel Nijpels, Nienke van Leeuwen, Louise A. Donnelly, Jacqueline M. Dekker, Marjan Alssema, Joao Fadista, Françoise Carlotti, Anette P. Gjesing, Colin N.A. Palmer, Timon W. van Haeften, Silke A. Herzberg-Schäfer, Annemarie M.C. Simonis-Bik, Jeanine J. Houwing-Duistermaat, Quinta Helmer, Joris Deelen, Bruno Guigas, Torben Hansen, Fausto Machicao, Gonneke Willemsen, Robert J. Heine, Mark H.H. Kramer, Jens J. Holst, Eelco J.P. de Koning, Hans-Ulrich Häring, Oluf Pedersen, Leif Groop, Eco J.C. de Geus, P. Eline Slagboom, Dorret I. Boomsma, Elisabeth M.W. Eekhoff, Ewan R. Pearson, Michaela Diamant
Journal: Diabetes
Diabetes 2013;62(9):3275–3281
https://doi.org/10.2337/db13-0227
Published: 15 August 2013
View article titled, The <em>CTRB1/2</em> Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway
Open the PDF for The <em>CTRB1/2</em> Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway in another window
Includes: Supplementary data
Journal Articles

Mendelian Randomization Studies Do Not Support a Role for Raised Circulating Triglyceride Levels Influencing Type 2 Diabetes, Glucose Levels, or Insulin Resistance

N. Maneka G. De Silva, Rachel M. Freathy, Tom M. Palmer, Louise A. Donnelly, Jian'an Luan, Tom Gaunt, Claudia Langenberg, Michael N. Weedon, Beverley Shields, Beatrice A. Knight, Kirsten J. Ward, Manjinder S. Sandhu, Roger M. Harbord, Mark I. McCarthy, George Davey Smith, Shah Ebrahim, Andrew T. Hattersley, Nicholas Wareham, Debbie A. Lawlor, Andrew D. Morris, Colin N.A. Palmer, Timothy M. Frayling
Journal: Diabetes
Diabetes 2011;60(3):1008–1018
https://doi.org/10.2337/db10-1317
Published: 21 February 2011
View article titled, Mendelian Randomization Studies Do Not Support a Role for Raised Circulating Triglyceride Levels Influencing Type 2 Diabetes, Glucose Levels, or Insulin Resistance
Open the PDF for Mendelian Randomization Studies Do Not Support a Role for Raised Circulating Triglyceride Levels Influencing Type 2 Diabetes, Glucose Levels, or Insulin Resistance in another window
Includes: Supplementary data
Journal Articles

Reduced-Function SLC22A1 Polymorphisms Encoding Organic Cation Transporter 1 and Glycemic Response to Metformin: A GoDARTS Study

Kaixin Zhou, Louise A. Donnelly, Charlotte H. Kimber, Peter T. Donnan, Alex S.F. Doney, Graham Leese, Andrew T. Hattersley, Mark I. McCarthy, Andrew D. Morris, Colin N.A. Palmer, Ewan R. Pearson
Journal: Diabetes
Diabetes 2009;58(6):1434–1439
https://doi.org/10.2337/db08-0896
Published: 31 March 2009
View article titled, Reduced-Function <em>SLC22A1</em> Polymorphisms Encoding Organic Cation Transporter 1 and Glycemic Response to Metformin: A GoDARTS Study
Open the PDF for Reduced-Function <em>SLC22A1</em> Polymorphisms Encoding Organic Cation Transporter 1 and Glycemic Response to Metformin: A GoDARTS Study in another window
Includes: Supplementary data
Journal Articles

Variation in TCF7L2 Influences Therapeutic Response to Sulfonylureas: A GoDARTs Study

Ewan R. Pearson, Louise A. Donnelly, Charlotte Kimber, Adrian Whitley, Alex S.F. Doney, Mark I. McCarthy, Andrew T. Hattersley, Andrew D. Morris, Colin N.A. Palmer
Journal: Diabetes
Diabetes 2007;56(8):2178–2182
https://doi.org/10.2337/db07-0440
Published: 01 August 2007
View article titled, Variation in <em>TCF7L2</em> Influences Therapeutic Response to Sulfonylureas: <subtitle>A GoDARTs Study</subtitle>
Open the PDF for Variation in <em>TCF7L2</em> Influences Therapeutic Response to Sulfonylureas: <subtitle>A GoDARTs Study</subtitle> in another window
Includes: Supplementary data