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Journal Articles

Emerging Concepts and Success Stories in Type 1 Diabetes Research: A Road Map for a Bright Future

Roberto Mallone, Emily Sims, Peter Achenbach, Chantal Mathieu, Alberto Pugliese, Mark Atkinson, Sanjoy Dutta, Carmella Evans-Molina, David Klatzmann, Anne Koralova, S. Alice Long, Lut Overbergh, Teresa Rodriguez-Calvo, Anette-Gabriele Ziegler, Sylvaine You

Diabetes 2025;74(1):12–21

https://doi.org/10.2337/db24-0439

Published: 24 October 2024

View article titled, Emerging Concepts and Success Stories in Type 1 Diabetes Research: A Road Map for a Bright Future

Journal Articles

CD4⁺ T Cells From Individuals With Type 1 Diabetes Respond to a Novel Class of Deamidated Peptides Formed in Pancreatic Islets

Aïsha Callebaut, Perrin Guyer, Rita Derua, Mijke Buitinga, Anthony Manganaro, Xiaoyan Yi, Fernanda Marques Câmara Sodré, Saurabh Vig, Mara Suleiman, Piero Marchetti, Decio L. Eizirik, Sally C. Kent, Chantal Mathieu, Eddie A. James, Lut Overbergh

Diabetes 2024;73(5):728–742

https://doi.org/10.2337/db23-0588

Published: 22 February 2024

View article titled, CD4<sup>+</sup> T Cells From Individuals With Type 1 Diabetes Respond to a Novel Class of Deamidated Peptides Formed in Pancreatic Islets

Journal Articles

An Insulin-Chromogranin A Hybrid Peptide Activates DR11-Restricted T Cells in Human Type 1 Diabetes

Aïsha Callebaut, Perrin Guyer, Rocky L. Baker, Joylynn B. Gallegos, Anita C. Hohenstein, Peter A. Gottlieb, Chantal Mathieu, Lut Overbergh, Kathryn Haskins, Eddie A. James

Diabetes 2024;73(5):743–750

https://doi.org/10.2337/db23-0622

Published: 31 January 2024

View article titled, An Insulin-Chromogranin A Hybrid Peptide Activates DR11-Restricted T Cells in Human Type 1 Diabetes

Journal Articles

CD8⁺ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes

Diabetes 2021;70(12):2879–2891

https://doi.org/10.2337/db21-0259

Published: 24 September 2021

View article titled, CD8<sup>+</sup> T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes

Journal Articles

Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice

Fernanda M.C. Sodré, Samal Bissenova, Ylke Bruggeman, Ronak Tilvawala, Dana P. Cook, Claire Berthault, Santanu Mondal, Aïsha Callebaut, Sylvaine You, Raphael Scharfmann, Roberto Mallone, Paul R. Thompson, Chantal Mathieu, Mijke Buitinga, Lut Overbergh

Diabetes 2021;70(2):516–528

https://doi.org/10.2337/db20-0421

Published: 17 November 2020

View article titled, Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice

Journal Articles

Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes

Mijke Buitinga, Aïsha Callebaut, Fernanda Marques Câmara Sodré, Inne Crèvecoeur, Gabriele Blahnik-Fagan, Mei-Ling Yang, Marco Bugliani, David Arribas-Layton, Meghan Marré, Dana P. Cook, Etienne Waelkens, Roberto Mallone, Jon D. Piganelli, Piero Marchetti, Mark J. Mamula, Rita Derua, Eddie A. James, Chantal Mathieu, Lut Overbergh

Diabetes 2018;67(11):2337–2348

https://doi.org/10.2337/db18-0295

Published: 11 October 2018

View article titled, Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes

Includes: Supplementary data

Journal Articles

Citrullinated Glucose-Regulated Protein 78 Is an Autoantigen in Type 1 Diabetes

Dieter Rondas, Inne Crèvecoeur, Wannes D’Hertog, Gabriela Bomfim Ferreira, An Staes, Abhishek D. Garg, Decio L. Eizirik, Patrizia Agostinis, Kris Gevaert, Lut Overbergh, Chantal Mathieu

Diabetes 2015;64(2):573–586

https://doi.org/10.2337/db14-0621

Published: 09 September 2014

View article titled, Citrullinated Glucose-Regulated Protein 78 Is an Autoantigen in Type 1 Diabetes

Includes: Supplementary data

Journal Articles

Posttranslational Modifications of Proteins in Type 1 Diabetes: The Next Step in Finding the Cure?

Jessica L. Dunne, Lut Overbergh, Anthony W. Purcell, Chantal Mathieu

Diabetes 2012;61(8):1907–1914

https://doi.org/10.2337/db11-1675

Published: 17 July 2012

View article titled, Posttranslational Modifications of Proteins in Type 1 Diabetes: The Next Step in Finding the Cure?

Journal Articles

Acute Shock Induced by Antigen Vaccination in NOD Mice

Lut Overbergh, Brigitte Decallonne, Dumitru D. Branisteanu, Dirk Valckx, Ahmad Kasran, Roger Bouillon, Chantal Mathieu

Diabetes 2003;52(2):335–341

https://doi.org/10.2337/diabetes.52.2.335

Published: 01 February 2003

View article titled, Acute Shock Induced by Antigen Vaccination in NOD Mice

NARROW

Emerging Concepts and Success Stories in Type 1 Diabetes Research: A Road Map for a Bright Future

CD4⁺ T Cells From Individuals With Type 1 Diabetes Respond to a Novel Class of Deamidated Peptides Formed in Pancreatic Islets

An Insulin-Chromogranin A Hybrid Peptide Activates DR11-Restricted T Cells in Human Type 1 Diabetes

CD8⁺ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes

Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice

Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes

Citrullinated Glucose-Regulated Protein 78 Is an Autoantigen in Type 1 Diabetes

Posttranslational Modifications of Proteins in Type 1 Diabetes: The Next Step in Finding the Cure?

Acute Shock Induced by Antigen Vaccination in NOD Mice

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