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Lynne E. Wagenknecht
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Meeting Abstracts

348-OR: Multiancestry Whole Genome Sequencing (WGS) Meta-analysis to Identify Loci Associated with Imaging-Measured Hepatic Steatosis

NICHOLETTE ALLRED, CHINMAY RAUT, YANHUA CHEN, ANTONINO OLIVERI, JEFFREY O'CONNELL, KATHLEEN RYAN, JEROME I. ROTTER, STEPHEN S. RICH, AARON HAKIM, PATRICIA PEYSER, LAWRENCE F. BIELAK, CHING-TI LIU, JAMES G. TERRY, MYRIAM FORNAGE, LYNNE E. WAGENKNECHT, ELIZABETH K. SPELIOTES, NHLBI TRANS-OMICS FOR PRECISION MEDICINE (TOPMED)PROGRAM, GOLD CONSORTIUM
Journal: Diabetes
Diabetes 2024;73(Supplement_1):348-OR
https://doi.org/10.2337/db24-348-OR
Published: 14 June 2024
View article titled, 348-OR: Multiancestry Whole Genome Sequencing (WGS) Meta-analysis to Identify Loci Associated with Imaging-Measured Hepatic Steatosis
Meeting Abstracts

365-OR: A Machine-Learning Approach to Estimate Insulin Resistance from Untargeted Metabolomics Data

NICHOLETTE ALLRED, FANG-CHI HSU, SHYH-HUEI CHEN, MAGGIE NG, MARK O. GOODARZI, JEROME I. ROTTER, LYNNE E. WAGENKNECHT, MICHAEL BANCKS, RICHARD N. BERGMAN, DONALD W. BOWDEN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):365-OR
https://doi.org/10.2337/db23-365-OR
Published: 20 June 2023
View article titled, 365-OR: A Machine-Learning Approach to Estimate Insulin Resistance from Untargeted Metabolomics Data
Meeting Abstracts

1-LB: Trends in Incidence and Age at Diagnosis of Youth-Onset Type 2 Diabetes, 2002–2018—The SEARCH for Diabetes in Youth Study

KATHERINE A. SAUDER, LYNNE E. WAGENKNECHT, ANGELA D. LIESE, DANA DABELEA, SANTICA M. MARCOVINA, CATHERINE PIHOKER, KRISTI REYNOLDS, AMY S. SHAH, LAWRENCE M. DOLAN, ANNA BELLATORRE, JEAN M. LAWRENCE, JASMIN DIVERS, ELIZABETH T. JENSEN
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1-LB
https://doi.org/10.2337/db22-1-LB
Published: 01 June 2022
View article titled, 1-LB: Trends in Incidence and Age at Diagnosis of Youth-Onset Type 2 Diabetes, 2002–2018—The SEARCH for Diabetes in Youth Study
Meeting Abstracts

1085-P: Exploring Racial and Ethnic Disparities in Arterial Stiffness in Type 1 Diabetes

KATHERINE A. SAUDER, DEBORAH H. GLUECK, KYLIE K. HARRALL, RALPH DAGOSTINO, LAWRENCE M. DOLAN, JR., ABBI LANE-CORDOVA, ANGELA D. LIESE, EVA LUSTIGOVA, FAISAL MALIK, SANTICA M. MARCOVINA, ELIZABETH J. MAYER-DAVIS, AMY K. MOTTL, CATHERINE PIHOKER, KRISTI REYNOLDS, AMY S. SHAH, ELAINE M. URBINA, LYNNE E. WAGENKNECHT, STEPHEN R. DANIELS, DANA DABELEA
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1085-P
https://doi.org/10.2337/db22-1085-P
Published: 01 June 2022
View article titled, 1085-P: Exploring Racial and Ethnic Disparities in Arterial Stiffness in Type 1 Diabetes
Meeting Abstracts

1084-P: Trends in Cardiovascular Risk Factors (CRF) for Youth with Incident Diabetes: The SEARCH for Diabetes in Youth Study

RONNY A. BELL, JOSEPH RIGDON, ANNA BELLATORRE, DANA DABELEA, RALPH DAGOSTINO, JASMIN DIVERS, JR., LAWRENCE M. DOLAN, GIUSEPPINA IMPERATORE, ELIZABETH T. JENSEN, ANGELA D. LIESE, EVA LUSTIGOVA, SANTICA M. MARCOVINA, LINA MERJANEH, DAVID J. PETTITT, CATHERINE PIHOKER, AMY S. SHAH, ANDREW M. SOUTH, LYNNE E. WAGENKNECHT
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1084-P
https://doi.org/10.2337/db22-1084-P
Published: 01 June 2022
View article titled, 1084-P: Trends in Cardiovascular Risk Factors (CRF) for Youth with Incident Diabetes: The SEARCH for Diabetes in Youth Study
Meeting Abstracts

1066-P: Association of T2D Subgroups with MCI/Dementia

MICHAEL BANCKS, JAMES LOVATO, ASHOK BALASUBRAMANYAM, MACE CODAY, KAREN C. JOHNSON, MEDHA MUNSHI, CANDIDA J. REBELLO, LYNNE E. WAGENKNECHT, MARK ESPELAND
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1066-P
https://doi.org/10.2337/db22-1066-P
Published: 01 June 2022
View article titled, 1066-P: Association of T2D Subgroups with MCI/Dementia
Meeting Abstracts

140-OR: Machine Learning for Metabolite Estimation to Examine Contributors to Glucose Homeostasis and Adiposity: The GUARDIAN Consortium

NICHOLETTE ALLRED, HANNAH C. AINSWORTH, XIUQING GUO, ADRIENNE W. MACKAY, FESTUS NYASIMI, OWEN MELIA, YANYU LIANG, DONALD W. BOWDEN, KENT TAYLOR, LESLIE J. RAFFEL, THOMAS A. BUCHANAN, RICHARD M. WATANABE, JEROME I. ROTTER, LYNNE E. WAGENKNECHT, CARL D. LANGEFELD, IV, HAE K. IM
Journal: Diabetes
Diabetes 2022;71(Supplement_1):140-OR
https://doi.org/10.2337/db22-140-OR
Published: 01 June 2022
View article titled, 140-OR: Machine Learning for Metabolite Estimation to Examine Contributors to Glucose Homeostasis and Adiposity: The GUARDIAN Consortium
Meeting Abstracts

352-OR: Proteomics of Incident Diabetes in Midlife: The Atherosclerosis Risk in Communities (ARIC) Study

MARY R. ROONEY, JINGSHA CHEN, OLIVE TANG, CHRISTIE M. BALLANTYNE, ERIC BOERWINKLE, JUSTIN ECHOUFFO TCHEUGUI, CHIADI E. NDUMELE, RYAN DEMMER, JAMES S. PANKOW, PAMELA LUTSEY, LYNNE E. WAGENKNECHT, MORGAN GRAMS, ELIZABETH SELVIN, JOSEF CORESH
Journal: Diabetes
Diabetes 2022;71(Supplement_1):352-OR
https://doi.org/10.2337/db22-352-OR
Published: 01 June 2022
View article titled, 352-OR: Proteomics of Incident Diabetes in Midlife: The Atherosclerosis Risk in Communities (ARIC) Study
Journal Articles

Erratum. The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium. Diabetes 2021;70:996–1005

Shylaja Srinivasan, Ling Chen, Jennifer Todd, Jasmin Divers, Samuel Gidding, Steven Chernausek, Rose A. Gubitosi-Klug, Megan M. Kelsey, Rachana Shah, Mary Helen Black, Lynne E. Wagenknecht, Alisa Manning, Jason Flannick, Giuseppina Imperatore, Josep M. Mercader, Dana Dabelea, Jose C. Florez
Journal: Diabetes
Diabetes 2022;71(1):170
https://doi.org/10.2337/db22-er01a
Published: 29 October 2021
View article titled, Erratum. The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium. Diabetes 2021;70:996–1005
Open the PDF for Erratum. The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium. Diabetes 2021;70:996–1005 in another window
Journal Articles

The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium

Shylaja Srinivasan, Ling Chen, Jennifer Todd, Jasmin Divers, Samuel Gidding, Steven Chernausek, Rose A. Gubitosi-Klug, Megan M. Kelsey, Rachana Shah, Mary Helen Black, Lynne E. Wagenknecht, Alisa Manning, Jason Flannick, Giuseppina Imperatore, Josep M. Mercader, Dana Dabelea, Jose C. Florez
Journal: Diabetes
Diabetes 2021;70(4):996–1005
https://doi.org/10.2337/db20-0443
Published: 21 January 2021
View article titled, The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium
Open the PDF for The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium in another window
Meeting Abstracts

58-OR: Diastolic Dysfunction, a Precursor for Heart Failure in Young Adults with Youth-Onset Type 1 and Type 2 Diabetes: The SEARCH for Diabetes in Youth Study

AMY S. SHAH, DANA DABELEA, LAWRENCE M. DOLAN, SCOTT ISOM, RALPH DAGOSTINO, JR., LYNNE E. WAGENKNECHT, GIUSEPPINA IMPERATORE, SHARON SAYDAH, ANGELA D. LIESE, JEAN M. LAWRENCE, CATHERINE PIHOKER, ELAINE M. URBINA
Journal: Diabetes
Diabetes 2020;69(Supplement_1):58-OR
https://doi.org/10.2337/db20-58-OR
Published: 01 June 2020
View article titled, 58-OR: Diastolic Dysfunction, a Precursor for Heart Failure in Young Adults with Youth-Onset Type 1 and Type 2 Diabetes: The SEARCH for Diabetes in Youth Study
Meeting Abstracts

143-OR: All-Cause Mortality over 16 Years in Look AHEAD

RENA R. WING, JEANNE CLARK, EDWARD W. GREGG, STEPHEN B. KRITCHEVSKY, CORA E. LEWIS, XAVIER PI-SUNYER, DAVID M. REBOUSSIN, THOMAS A. WADDEN, LYNNE E. WAGENKNECHT, SUSAN Z. YANOVSKI, THE LOOK AHEAD GROUP
Journal: Diabetes
Diabetes 2020;69(Supplement_1):143-OR
https://doi.org/10.2337/db20-143-OR
Published: 01 June 2020
View article titled, 143-OR: All-Cause Mortality over 16 Years in Look AHEAD
Meeting Abstracts

1998-P: Waist Circumference Change in the First Year of the Look AHEAD Trial Is Associated with Risk for Cardiovascular Morbidity and Mortality

KAYLONI L. OLSON, REBECCA H. NEIBERG, MARK ESPELAND, KAREN C. JOHNSON, WILLIAM C. KNOWLER, XAVIER PI-SUNYER, AMANDA E. STAIANO, LYNNE E. WAGENKNECHT, RENA R. WING, THE LOOK AHEAD GROUP
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1998-P
https://doi.org/10.2337/db20-1998-P
Published: 01 June 2020
View article titled, 1998-P: Waist Circumference Change in the First Year of the Look AHEAD Trial Is Associated with Risk for Cardiovascular Morbidity and Mortality
Meeting Abstracts

1441-P: Predicting Diabetes (DM) Diagnoses Dates Using the Electronic Health Record (EHR)

KRISTIN M. LENOIR, LYNNE E. WAGENKNECHT, JASMIN DIVERS, RAMON CASANOVA, JEAN M. LAWRENCE, DANA DABELEA, CATHERINE PIHOKER, SHARON SAYDAH, ANGELA D. LIESE, DEBRA STANDIFORD, BRIAN J. WELLS
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1441-P
https://doi.org/10.2337/db20-1441-P
Published: 01 June 2020
View article titled, 1441-P: Predicting Diabetes (DM) Diagnoses Dates Using the Electronic Health Record (EHR)
Meeting Abstracts

82-OR: A T1D Genetic Risk Score Combined with Clinical Features and Autoantibodies Enables Accurate Diabetes Classification in a Racial/Ethnically Diverse Population: The Search for Diabetes in Youth Study

RICHARD A. ORAM, SETH A. SHARP, CATHERINE PIHOKER, LAURIC A. FERRAT, GIUSEPPINA IMPERATORE, SHARON SAYDAH, ADRIENNE H. WILLIAMS, LYNNE E. WAGENKNECHT, JEAN M. LAWRENCE, MICHAEL N. WEEDON, RALPH DAGOSTINO, JR., WILLIAM HAGOPIAN, JASMIN DIVERS, DANA DABELEA
Journal: Diabetes
Diabetes 2019;68(Supplement_1):82-OR
https://doi.org/10.2337/db19-82-OR
Published: 01 June 2019
View article titled, 82-OR: A T1D Genetic Risk Score Combined with Clinical Features and Autoantibodies Enables Accurate Diabetes Classification in a Racial/Ethnically Diverse Population: The Search for Diabetes in Youth Study
Meeting Abstracts

1576-P: Metabolomic Profiling of the Dietary Approaches to Stop Hypertension (DASH) Diet: Novel Insights for the Nutritional Epidemiology of Type 2 Diabetes Mellitus (T2DM)

SHAHEN YASHPAL, ANGELA D. LIESE, LYNNE E. WAGENKNECHT, STEVEN M. HAFFNER, LUKE W. JOHNSTON, BEATRICE BOUCHER, RICHARD P. BAZINET, MARIAN REWERS, JEROME I. ROTTER, STEVE M. WATKINS, ANTHONY HANLEY
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1576-P
https://doi.org/10.2337/db19-1576-P
Published: 01 June 2019
View article titled, 1576-P: Metabolomic Profiling of the Dietary Approaches to Stop Hypertension (DASH) Diet: Novel Insights for the Nutritional Epidemiology of Type 2 Diabetes Mellitus (T2DM)
Meeting Abstracts

1305-P: Detection of Diabetes Status and Type in Youth Using EMRs

BRIAN J. WELLS, KRISTIN M. LENOIR, LYNNE E. WAGENKNECHT, ELIZABETH MAYER-DAVIS, DANA DABELEA, JEAN M. LAWRENCE, CATHERINE PIHOKER, SHARON SAYDAH, GIUSEPPINA IMPERATORE, RAMON CASANOVA, CHRISTINE B. TURLEY, ANGELA D. LIESE, DEBRA STANDIFORD, RICHARD F. HAMMAN, MICHAEL G. KAHN, JASMIN DIVERS
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1305-P
https://doi.org/10.2337/db19-1305-P
Published: 01 June 2019
View article titled, 1305-P: Detection of Diabetes Status and Type in Youth Using EMRs
Meeting Abstracts

The First Genome-Wide Association Study (GWAS) for Type 2 Diabetes in Youth from the Progress in Diabetes Genetics in Youth (ProDiGY) Collaboration

SHYLAJA SRINIVASAN, JENNIFER TODD, LING CHEN, JASMIN DIVERS, SAM GIDDING, STEVEN CHERNAUSEK, ROSE GUBITOSI-KLUG, MEGAN M. KELSEY, RACHANA SHAH, MARY HELEN BLACK, LYNNE E. WAGENKNECHT, JOSE M. MERCADER, ALISA MANNING, JASON FLANNICK, DANA DABELEA, JOSE C. FLOREZ
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1703-P
https://doi.org/10.2337/db18-1703-P
Published: 01 July 2018
View article titled, The First Genome-Wide Association Study (GWAS) for Type 2 Diabetes in Youth from the Progress in Diabetes Genetics in Youth (ProDiGY) Collaboration
Journal Articles

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

Andrew R. Wood, Anna Jonsson, Anne U. Jackson, Nan Wang, Nienke van Leewen, Nicholette D. Palmer, Sayuko Kobes, Joris Deelen, Lorena Boquete-Vilarino, Jussi Paananen, Alena Stančáková, Dorret I. Boomsma, Eco J.C. de Geus, Elisabeth M.W. Eekhoff, Andreas Fritsche, Mark Kramer, Giel Nijpels, Annemarie Simonis-Bik, Timon W. van Haeften, Anubha Mahajan, Michael Boehnke, Richard N. Bergman, Jaakko Tuomilehto, Francis S. Collins, Karen L. Mohlke, Karina Banasik, Christopher J. Groves, Mark I. McCarthy, Diabetes Research on Patient Stratification (DIRECT), Ewan R. Pearson, Andrea Natali, Andrea Mari, Thomas A. Buchanan, Kent D. Taylor, Anny H. Xiang, Anette P. Gjesing, Niels Grarup, Hans Eiberg, Oluf Pedersen, Yii-Derr Chen, Markku Laakso, Jill M. Norris, Ulf Smith, Lynne E. Wagenknecht, Leslie Baier, Donald W. Bowden, Torben Hansen, Mark Walker, Richard M. Watanabe, Leen M. ‘t Hart, Robert L. Hanson, Timothy M. Frayling
Journal: Diabetes
Diabetes 2017;66(8):2296–2309
https://doi.org/10.2337/db16-1452
Published: 10 May 2017
View article titled, A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants
Open the PDF for A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants in another window
Includes: Supplementary data
Journal Articles

Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium

Nicholette D. Palmer, Lynne E. Wagenknecht, Carl D. Langefeld, Nan Wang, Thomas A. Buchanan, Anny H. Xiang, Hooman Allayee, Richard N. Bergman, Leslie J. Raffel, Yii-Der Ida Chen, Talin Haritunians, Tasha Fingerlin, Mark O. Goodarzi, Kent D. Taylor, Jerome I. Rotter, Richard M. Watanabe, Donald W. Bowden
Journal: Diabetes
Diabetes 2016;65(7):2072–2080
https://doi.org/10.2337/db15-1543
Published: 03 May 2016
View article titled, Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium
Open the PDF for Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium in another window
Includes: Supplementary data