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Meeting Abstracts

224-OR: Effect of PD-L1 Overexpression on Autoreactive T-Cell Responses toward Stem Cell–Derived Beta Cells

JESSIE BARRA, ROBERTO CASTRO-GUTIERREZ, JORGE SANTINI-GONZALEZ, CAMERON MANSON, ADRIENNE WIDENER, LAURIE LANDRY, MAKI NAKAYAMA, EDWARD PHELPS, HOLGER A. RUSS

Diabetes 2024;73(Supplement_1):224-OR

https://doi.org/10.2337/db24-224-OR

Published: 14 June 2024

View article titled, 224-OR: Effect of PD-L1 Overexpression on Autoreactive T-Cell Responses toward Stem Cell–Derived Beta Cells

Journal Articles

Cell-Surface Autoantibody Targets Zinc Transporter-8 (ZnT8) for In Vivo β-Cell Imaging and Islet-Specific Therapies

Zheng Guo, Devi Kasinathan, Chengfeng Merriman, Maki Nakayama, Hua Li, Huilin Li, Cheng Xu, G. William Wong, Liping Yu, Maria L. Golson, Dax Fu

Diabetes 2023;72(2):184–195

https://doi.org/10.2337/db22-0477

Published: 30 November 2022

View article titled, Cell-Surface Autoantibody Targets Zinc Transporter-8 (ZnT8) for In Vivo β-Cell Imaging and Islet-Specific Therapies

Meeting Abstracts

185-OR: T-Cell Receptor Repertoires during Type 1 Diabetes Development

ANGELA M. MITCHELL, ERIN E. BASCHAL, KRISTEN MCDANIEL, LAURA PYLE, KATHLEEN WAUGH, ANDREA STECK, LIPING YU, PETER GOTTLIEB, MARIAN REWERS, MAKI NAKAYAMA, AARON W. MICHELS

Diabetes 2022;71(Supplement_1):185-OR

https://doi.org/10.2337/db22-185-OR

Published: 01 June 2022

View article titled, 185-OR: T-Cell Receptor Repertoires during Type 1 Diabetes Development

Journal Articles

CD8⁺ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes

Diabetes 2021;70(12):2879–2891

https://doi.org/10.2337/db21-0259

Published: 24 September 2021

View article titled, CD8<sup>+</sup> T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes

Meeting Abstracts

108-OR: Islet-Derived Preproinsulin T Cell Receptor Sequences Are Present throughout the Stages of Type 1 Diabetes Development

ERIN E. BASCHAL, ANGELA M. MITCHELL, KRISTEN MCDANIEL, AIMON ALKANANI, TAYLOR ARMSTRONG, LAURIE LANDRY, KATHLEEN WAUGH, MARIAN REWERS, MAKI NAKAYAMA, AARON W. MICHELS

Diabetes 2021;70(Supplement_1):108-OR

https://doi.org/10.2337/db21-108-OR

Published: 01 June 2021

View article titled, 108-OR: Islet-Derived Preproinsulin T Cell Receptor Sequences Are Present throughout the Stages of Type 1 Diabetes Development

Meeting Abstracts

109-OR: T-Cell Responses to Hybrid Insulin Peptides Precede Type 1 Diabetes Development

ANGELA M. MITCHELL, AIMON ALKANANI, KRISTEN MCDANIEL, LAURA PYLE, KATHLEEN WAUGH, ANDREA STECK, MAKI NAKAYAMA, LIPING YU, PETER GOTTLIEB, MARIAN REWERS, AARON W. MICHELS

Diabetes 2021;70(Supplement_1):109-OR

https://doi.org/10.2337/db21-109-OR

Published: 01 June 2021

View article titled, 109-OR: T-Cell Responses to Hybrid Insulin Peptides Precede Type 1 Diabetes Development

Journal Articles

Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances

Simi Ahmed, Karen Cerosaletti, Eddie James, S. Alice Long, Stuart Mannering, Cate Speake, Maki Nakayama, Timothy Tree, Bart O. Roep, Kevan C. Herold, Todd M. Brusko

Diabetes 2019;68(7):1366–1379

https://doi.org/10.2337/db19-0119

Published: 13 June 2019

View article titled, Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances

Includes: Supplementary data

Journal Articles

Hybrid Insulin Peptides Are Autoantigens in Type 1 Diabetes

Rocky L. Baker, Marynette Rihanek, Anita C. Hohenstein, Maki Nakayama, Aaron Michels, Peter A. Gottlieb, Kathryn Haskins, Thomas Delong

Diabetes 2019;68(9):1830–1840

https://doi.org/10.2337/db19-0128

Published: 07 June 2019

View article titled, Hybrid Insulin Peptides Are Autoantigens in Type 1 Diabetes

Includes: Supplementary data

Journal Articles

CD4 T Cells Reactive to Hybrid Insulin Peptides Are Indicators of Disease Activity in the NOD Mouse

Rocky L. Baker, Braxton L. Jamison, Timothy A. Wiles, Robin S. Lindsay, Gene Barbour, Brenda Bradley, Thomas Delong, Rachel S. Friedman, Maki Nakayama, Kathryn Haskins

Diabetes 2018;67(9):1836–1846

https://doi.org/10.2337/db18-0200

Published: 05 July 2018

View article titled, CD4 T Cells Reactive to Hybrid Insulin Peptides Are Indicators of Disease Activity in the NOD Mouse

Includes: Supplementary data

Journal Articles

Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes

Aaron W. Michels, Laurie G. Landry, Kristen A. McDaniel, Liping Yu, Martha Campbell-Thompson, William W. Kwok, Kenneth L. Jones, Peter A. Gottlieb, John W. Kappler, Qizhi Tang, Bart O. Roep, Mark A. Atkinson, Clayton E. Mathews, Maki Nakayama

Diabetes 2017;66(3):722–734

https://doi.org/10.2337/db16-1025

Published: 05 December 2016

View article titled, Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes

Includes: Supplementary data

Journal Articles

Paradigm Shift or Shifting Paradigm for Type 1 Diabetes

Maki Nakayama, George S. Eisenbarth

Diabetes 2012;61(5):976–978

https://doi.org/10.2337/db12-0057

Published: 13 April 2012

View article titled, Paradigm Shift or Shifting Paradigm for Type 1 Diabetes

Journal Articles

Following the Fate of One Insulin-Reactive CD4 T cell: Conversion Into Teffs and Tregs in the Periphery Controls Diabetes in NOD Mice

Georgia Fousteri, Jean Jasinski, Amy Dave, Maki Nakayama, Philippe Pagni, Florence Lambolez, Therese Juntti, Ghanashyam Sarikonda, Yang Cheng, Michael Croft, Hilde Cheroutre, George Eisenbarth, Matthias von Herrath

Diabetes 2012;61(5):1169–1179

https://doi.org/10.2337/db11-0671

Published: 13 April 2012

View article titled, Following the Fate of One Insulin-Reactive CD4 T cell: <subtitle>Conversion Into Teffs and Tregs in the Periphery Controls Diabetes in NOD Mice</subtitle>

Includes: Supplementary data

Journal Articles

Germline TRAV5D-4 T-Cell Receptor Sequence Targets a Primary Insulin Peptide of NOD Mice

Maki Nakayama, Todd Castoe, Tomasz Sosinowski, XiangLing He, Kelly Johnson, Kathryn Haskins, Dario A.A. Vignali, Laurent Gapin, David Pollock, George S. Eisenbarth

Diabetes 2012;61(4):857–865

https://doi.org/10.2337/db11-1113

Published: 14 March 2012

View article titled, Germline TRAV5D-4 T-Cell Receptor Sequence Targets a Primary Insulin Peptide of NOD Mice

Includes: Supplementary data

Journal Articles

Transgenic Insulin (B:9-23) T-Cell Receptor Mice Develop Autoimmune Diabetes Dependent Upon RAG Genotype, H-2^g7 Homozygosity, and Insulin 2 Gene Knockout

Jean M. Jasinski, Liping Yu, Maki Nakayama, Marcella M. Li, Myra A. Lipes, George S. Eisenbarth, Edwin Liu

Diabetes 2006;55(7):1978–1984

https://doi.org/10.2337/db06-0058

Published: 01 July 2006

View article titled, Transgenic Insulin (B:9-23) T-Cell Receptor Mice Develop Autoimmune Diabetes Dependent Upon RAG Genotype, H-2<sup>g7</sup> Homozygosity, and Insulin 2 Gene Knockout

Journal Articles

Interferon-α as a Mediator of Polyinosinic:Polycytidylic Acid–Induced Type 1 Diabetes

Devasenan Devendra, Jean Jasinski, Evie Melanitou, Maki Nakayama, Marcella Li, Brooke Hensley, Johanna Paronen, Hiroaki Moriyama, Dongmei Miao, George S. Eisenbarth, Edwin Liu

Diabetes 2005;54(9):2549–2556

https://doi.org/10.2337/diabetes.54.9.2549

Published: 01 September 2005

View article titled, Interferon-α as a Mediator of Polyinosinic:Polycytidylic Acid–Induced Type 1 Diabetes

Journal Articles

Fas/Fas Ligand Interactions Play an Essential Role in the Initiation of Murine Autoimmune Diabetes

Maki Nakayama, Masao Nagata, Hisafumi Yasuda, Kenji Arisawa, Reiko Kotani, Katsumi Yamada, Shahead Ali Chowdhury, Sagarika Chakrabarty, Zhen Zi Jin, Hideo Yagita, Koichi Yokono, Masato Kasuga

Diabetes 2002;51(5):1391–1397

https://doi.org/10.2337/diabetes.51.5.1391

Published: 01 May 2002

View article titled, Fas/Fas Ligand Interactions Play an Essential Role in the Initiation of Murine Autoimmune Diabetes

NARROW

224-OR: Effect of PD-L1 Overexpression on Autoreactive T-Cell Responses toward Stem Cell–Derived Beta Cells

Cell-Surface Autoantibody Targets Zinc Transporter-8 (ZnT8) for In Vivo β-Cell Imaging and Islet-Specific Therapies

185-OR: T-Cell Receptor Repertoires during Type 1 Diabetes Development

CD8⁺ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes

108-OR: Islet-Derived Preproinsulin T Cell Receptor Sequences Are Present throughout the Stages of Type 1 Diabetes Development

109-OR: T-Cell Responses to Hybrid Insulin Peptides Precede Type 1 Diabetes Development

Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances

Hybrid Insulin Peptides Are Autoantigens in Type 1 Diabetes

CD4 T Cells Reactive to Hybrid Insulin Peptides Are Indicators of Disease Activity in the NOD Mouse

Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes

Paradigm Shift or Shifting Paradigm for Type 1 Diabetes

Following the Fate of One Insulin-Reactive CD4 T cell: Conversion Into Teffs and Tregs in the Periphery Controls Diabetes in NOD Mice

Germline TRAV5D-4 T-Cell Receptor Sequence Targets a Primary Insulin Peptide of NOD Mice

Transgenic Insulin (B:9-23) T-Cell Receptor Mice Develop Autoimmune Diabetes Dependent Upon RAG Genotype, H-2^g7 Homozygosity, and Insulin 2 Gene Knockout

Interferon-α as a Mediator of Polyinosinic:Polycytidylic Acid–Induced Type 1 Diabetes

Fas/Fas Ligand Interactions Play an Essential Role in the Initiation of Murine Autoimmune Diabetes

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