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Maria Bettini
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Journal Articles

Antibody-Mediated Targeting of a Hybrid Insulin Peptide Toward Neonatal Thymic Langerin-Positive Cells Enhances T-Cell Central Tolerance and Delays Autoimmune Diabetes

Yong Lin, Jelena Perovanovic, Yuelin Kong, Botond Z. Igyarto, Sandra Zurawski, Dean Tantin, Gerard Zurawski, Maria Bettini, Matthew L. Bettini
Journal: Diabetes
Diabetes 2022;71(8):1735–1745
https://doi.org/10.2337/db21-1069
Published: 21 August 2022
View article titled, Antibody-Mediated Targeting of a Hybrid Insulin Peptide Toward Neonatal Thymic Langerin-Positive Cells Enhances T-Cell Central Tolerance and Delays Autoimmune Diabetes
Open the PDF for Antibody-Mediated Targeting of a Hybrid Insulin Peptide Toward Neonatal Thymic Langerin-Positive Cells Enhances T-Cell Central Tolerance and Delays Autoimmune Diabetes in another window
Journal Articles

T-Cell Receptor/HLA Humanized Mice Reveal Reduced Tolerance and Increased Immunogenicity of Posttranslationally Modified GAD65 Epitope

Yi Jing, Yuelin Kong, John McGinty, Gabriele Blahnik-Fagan, Thomas Lee, Stephanie Orozco-Figueroa, Matthew L. Bettini, Eddie A. James, Maria Bettini
Journal: Diabetes
Diabetes 2022;71(5):1012–1022
https://doi.org/10.2337/db21-0993
Published: 18 February 2022
View article titled, T-Cell Receptor/HLA Humanized Mice Reveal Reduced Tolerance and Increased Immunogenicity of Posttranslationally Modified GAD65 Epitope
Open the PDF for T-Cell Receptor/HLA Humanized Mice Reveal Reduced Tolerance and Increased Immunogenicity of Posttranslationally Modified GAD65 Epitope in another window
Journal Articles

Function, Failure, and the Future Potential of Tregs in Type 1 Diabetes

Maria Bettini, Matthew L. Bettini
Journal: Diabetes
Diabetes 2021;70(6):1211–1219
https://doi.org/10.2337/dbi18-0058
Published: 02 July 2021
View article titled, Function, Failure, and the Future Potential of Tregs in Type 1 Diabetes
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Journal Articles

A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells

Maria Bettini, Marissa A. Scavuzzo, Baoyu Liu, Elizabeth Kolawole, Lin Guo, Brian D. Evavold, Malgorzata Borowiak, Matthew L. Bettini
Journal: Diabetes
Diabetes 2020;69(3):392–400
https://doi.org/10.2337/db19-0821
Published: 13 December 2020
View article titled, A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells
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Includes: Supplementary data
Journal Articles

A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery

Baoyu Liu, Jennifer D. Hood, Elizabeth M. Kolawole, Derek M. Woodruff, Dario A. Vignali, Maria Bettini, Brian D. Evavold
Journal: Diabetes
Diabetes 2020;69(3):381–391
https://doi.org/10.2337/db19-0399
Published: 05 December 2020
View article titled, A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery
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Meeting Abstracts

287-OR: TCR/HLA Humanized Mice Reveal Reduced Tolerance and Increased Immunogenicity of Posttranslationally Modified GAD65 Epitope

YI JING, YUELIN KONG, JOHN MCGINTY, GABRIELE BLAHNIK-FAGAN, MATTHEW BETTINI, EDDIE A. JAMES, MARIA BETTINI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):287-OR
https://doi.org/10.2337/db20-287-OR
Published: 01 June 2020
View article titled, 287-OR: TCR/HLA Humanized Mice Reveal Reduced Tolerance and Increased Immunogenicity of Posttranslationally Modified GAD65 Epitope
Meeting Abstracts

Thymic Development of Beta-Cell Specific Regulatory T Cells in Neonatal NOD Mice

YONG LIN, THOMAS LEE, MARIA BETTINI, MATTHEW BETTINI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):316-OR
https://doi.org/10.2337/db18-316-OR
Published: 01 July 2018
View article titled, Thymic Development of Beta-Cell Specific Regulatory T Cells in Neonatal NOD Mice
Meeting Abstracts

Self-Reactivity and T-Cell Receptor Repertoire of Effector and Regulatory T Cells in Autoimmune Diabetes

YUELIN KONG, MARAN L. SPROUSE, YI JING, MATTHEW BETTINI, MARIA BETTINI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2418-PUB
https://doi.org/10.2337/db18-2418-PUB
Published: 01 July 2018
View article titled, Self-Reactivity and T-Cell Receptor Repertoire of Effector and Regulatory T Cells in Autoimmune Diabetes
Journal Articles

Prevention of Autoimmune Diabetes by Ectopic Pancreatic β-Cell Expression of Interleukin-35

Maria Bettini, Ashley H. Castellaw, Greig P. Lennon, Amanda R. Burton, Dario A.A. Vignali
Journal: Diabetes
Diabetes 2012;61(6):1519–1526
https://doi.org/10.2337/db11-0784
Published: 14 May 2012
View article titled, Prevention of Autoimmune Diabetes by Ectopic Pancreatic β-Cell Expression of Interleukin-35
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Includes: Supplementary data