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Mark A. Febbraio
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Journal Articles

Activating HSP72 in Rodent Skeletal Muscle Increases Mitochondrial Number and Oxidative Capacity and Decreases Insulin Resistance

Darren C. Henstridge, Clinton R. Bruce, Brian G. Drew, Kálmán Tory, Attila Kolonics, Emma Estevez, Jason Chung, Nadine Watson, Timothy Gardner, Robert S. Lee-Young, Timothy Connor, Matthew J. Watt, Kevin Carpenter, Mark Hargreaves, Sean L. McGee, Andrea L. Hevener, Mark A. Febbraio
Journal: Diabetes
Diabetes 2014;63(6):1881–1894
https://doi.org/10.2337/db13-0967
Published: 15 May 2014
View article titled, Activating HSP72 in Rodent Skeletal Muscle Increases Mitochondrial Number and Oxidative Capacity and Decreases Insulin Resistance
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Includes: Supplementary data
Journal Articles

HSP72 Is a Mitochondrial Stress Sensor Critical for Parkin Action, Oxidative Metabolism, and Insulin Sensitivity in Skeletal Muscle

Brian G. Drew, Vicente Ribas, Jamie A. Le, Darren C. Henstridge, Jennifer Phun, Zhenqi Zhou, Teo Soleymani, Pedram Daraei, Daniel Sitz, Laurent Vergnes, Jonathan Wanagat, Karen Reue, Mark A. Febbraio, Andrea L. Hevener
Journal: Diabetes
Diabetes 2014;63(5):1488–1505
https://doi.org/10.2337/db13-0665
Published: 12 April 2014
View article titled, HSP72 Is a Mitochondrial Stress Sensor Critical for Parkin Action, Oxidative Metabolism, and Insulin Sensitivity in Skeletal Muscle
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Includes: Supplementary data
Journal Articles

Interleukin-18 Activates Skeletal Muscle AMPK and Reduces Weight Gain and Insulin Resistance in Mice

Birgitte Lindegaard, Vance B. Matthews, Claus Brandt, Pernille Hojman, Tamara L. Allen, Emma Estevez, Matthew J. Watt, Clinton R. Bruce, Ole H. Mortensen, Susanne Syberg, Caroline Rudnicka, Julie Abildgaard, Henriette Pilegaard, Juan Hidalgo, Susanne Ditlevsen, Thomas J. Alsted, Andreas N. Madsen, Bente K. Pedersen, Mark A. Febbraio
Journal: Diabetes
Diabetes 2013;62(9):3064–3074
https://doi.org/10.2337/db12-1095
Published: 15 August 2013
View article titled, Interleukin-18 Activates Skeletal Muscle AMPK and Reduces Weight Gain and Insulin Resistance in Mice
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Includes: Supplementary data
Journal Articles

Overexpression of Sphingosine Kinase 1 Prevents Ceramide Accumulation and Ameliorates Muscle Insulin Resistance in High-Fat Diet–Fed Mice

Clinton R. Bruce, Steve Risis, Joanne R. Babb, Christine Yang, Greg M. Kowalski, Ahrathy Selathurai, Robert S. Lee-Young, Jacquelyn M. Weir, Kazuaki Yoshioka, Yoh Takuwa, Peter J. Meikle, Stuart M. Pitson, Mark A. Febbraio
Journal: Diabetes
Diabetes 2012;61(12):3148–3155
https://doi.org/10.2337/db12-0029
Published: 15 November 2012
View article titled, Overexpression of Sphingosine Kinase 1 Prevents Ceramide Accumulation and Ameliorates Muscle Insulin Resistance in High-Fat Diet–Fed Mice
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Includes: Supplementary data
Journal Articles

Hematopoietic Cell–Restricted Deletion of CD36 Reduces High-Fat Diet–Induced Macrophage Infiltration and Improves Insulin Signaling in Adipose Tissue

Hayley T. Nicholls, Greg Kowalski, David J. Kennedy, Steve Risis, Lee A. Zaffino, Nadine Watson, Peter Kanellakis, Matthew J. Watt, Alex Bobik, Arend Bonen, Maria Febbraio, Graeme I. Lancaster, Mark A. Febbraio
Journal: Diabetes
Diabetes 2011;60(4):1100–1110
https://doi.org/10.2337/db10-1353
Published: 22 March 2011
View article titled, Hematopoietic Cell–Restricted Deletion of CD36 Reduces High-Fat Diet–Induced Macrophage Infiltration and Improves Insulin Signaling in Adipose Tissue
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Includes: Supplementary data
Journal Articles

Overexpression of Carnitine Palmitoyltransferase-1 in Skeletal Muscle Is Sufficient to Enhance Fatty Acid Oxidation and Improve High-Fat Diet–Induced Insulin Resistance

Clinton R. Bruce, Andrew J. Hoy, Nigel Turner, Matthew J. Watt, Tamara L. Allen, Kevin Carpenter, Gregory J. Cooney, Mark A. Febbraio, Edward W. Kraegen
Journal: Diabetes
Diabetes 2009;58(3):550–558
https://doi.org/10.2337/db08-1078
Published: 01 March 2009
View article titled, Overexpression of Carnitine Palmitoyltransferase-1 in Skeletal Muscle Is Sufficient to Enhance Fatty Acid Oxidation and Improve High-Fat Diet–Induced Insulin Resistance
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Includes: Supplementary data
Journal Articles

Interleukin-6 Attenuates Insulin-Mediated Increases in Endothelial Cell Signaling but Augments Skeletal Muscle Insulin Action via Differential Effects on Tumor Necrosis Factor-α Expression

Derek Y.C. Yuen, Renee M. Dwyer, Vance B. Matthews, Lei Zhang, Brian G. Drew, Bronwyn Neill, Bronwyn A. Kingwell, Michael G. Clark, Stephen Rattigan, Mark A. Febbraio
Journal: Diabetes
Diabetes 2009;58(5):1086–1095
https://doi.org/10.2337/db08-0775
Published: 02 February 2009
View article titled, Interleukin-6 Attenuates Insulin-Mediated Increases in Endothelial Cell Signaling but Augments Skeletal Muscle Insulin Action via Differential Effects on Tumor Necrosis Factor-α Expression
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Includes: Supplementary data
Journal Articles

Tissue-Specific Effects of Rosiglitazone and Exercise in the Treatment of Lipid-Induced Insulin Resistance

Sarah J. Lessard, Donato A. Rivas, Zhi-Ping Chen, Arend Bonen, Mark A. Febbraio, Donald W. Reeder, Bruce E. Kemp, Ben B. Yaspelkis, III, John A. Hawley
Journal: Diabetes
Diabetes 2007;56(7):1856–1864
https://doi.org/10.2337/db06-1065
Published: 01 July 2007
View article titled, Tissue-Specific Effects of Rosiglitazone and Exercise in the Treatment of Lipid-Induced Insulin Resistance
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Journal Articles

Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase

Andrew L. Carey, Gregory R. Steinberg, S. Lance Macaulay, Walter G. Thomas, Anna G. Holmes, Georg Ramm, Oja Prelovsek, Cordula Hohnen-Behrens, Matthew J. Watt, David E. James, Bruce E. Kemp, Bente K. Pedersen, Mark A. Febbraio
Journal: Diabetes
Diabetes 2006;55(10):2688–2697
https://doi.org/10.2337/db05-1404
Published: 01 October 2006
View article titled, Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase
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Journal Articles

Interleukin-6 Is a Novel Factor Mediating Glucose Homeostasis During Skeletal Muscle Contraction

Mark A. Febbraio, Natalie Hiscock, Massimo Sacchetti, Christian P. Fischer, Bente K. Pedersen
Journal: Diabetes
Diabetes 2004;53(7):1643–1648
https://doi.org/10.2337/diabetes.53.7.1643
Published: 01 July 2004
View article titled, Interleukin-6 Is a Novel Factor Mediating Glucose Homeostasis During Skeletal Muscle Contraction
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Journal Articles

Intramuscular Heat Shock Protein 72 and Heme Oxygenase-1 mRNA Are Reduced in Patients With Type 2 Diabetes: Evidence That Insulin Resistance Is Associated With a Disturbed Antioxidant Defense Mechanism

Clinton R. Bruce, Andrew L. Carey, John A. Hawley, Mark A. Febbraio
Journal: Diabetes
Diabetes 2003;52(9):2338–2345
https://doi.org/10.2337/diabetes.52.9.2338
Published: 01 September 2003
View article titled, Intramuscular Heat Shock Protein 72 and Heme Oxygenase-1 mRNA Are Reduced in Patients With Type 2 Diabetes: <subtitle>Evidence That Insulin Resistance Is Associated With a Disturbed Antioxidant Defense Mechanism</subtitle>
Open the PDF for Intramuscular Heat Shock Protein 72 and Heme Oxygenase-1 mRNA Are Reduced in Patients With Type 2 Diabetes: <subtitle>Evidence That Insulin Resistance Is Associated With a Disturbed Antioxidant Defense Mechanism</subtitle> in another window