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Marta S. Smith
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Meeting Abstracts

1563-P: High Fat and Fructose Feeding Severely Impairs Hepatic Glucose Effectiveness but Not Insulin Action Under Euglycemic Conditions

DALE S. EDGERTON, GUILLAUME KRAFT, HANNAH L. WATERMAN, BEN FARMER, KALISHA YANKEY, MARTA S. SMITH, JON R. HASTINGS, MELANIE SCOTT, ALAN D. CHERRINGTON
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1563-P
https://doi.org/10.2337/db24-1563-P
Published: 14 June 2024
View article titled, 1563-P: High Fat and Fructose Feeding Severely Impairs Hepatic Glucose Effectiveness but Not Insulin Action Under Euglycemic Conditions
Meeting Abstracts

1565-P: Morning Hyperglucagonemia Disrupts the Priming Action of AM Insulin

HANNAH L. WATERMAN, MARY C. MOORE, MARTA S. SMITH, BEN FARMER, KALISHA YANKEY, DALE S. EDGERTON, ALAN D. CHERRINGTON
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1565-P
https://doi.org/10.2337/db24-1565-P
Published: 14 June 2024
View article titled, 1565-P: Morning Hyperglucagonemia Disrupts the Priming Action of AM Insulin
Meeting Abstracts

1600-P: Duration of Morning Hyperinsulinemia Is Key to the Enhancement of Hepatic Glucose Uptake Later in the Day

HANNAH L. WATERMAN, MARTA S. SMITH, BEN FARMER, GUILLAUME KRAFT, MELANIE SCOTT, DALE S. EDGERTON, ALAN D. CHERRINGTON, MARY C. MOORE
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1600-P
https://doi.org/10.2337/db23-1600-P
Published: 20 June 2023
View article titled, 1600-P: Duration of Morning Hyperinsulinemia Is Key to the Enhancement of Hepatic Glucose Uptake Later in the Day
Meeting Abstracts

1560-P: Combining Glucagon with Insulin Can Lessen the Hypoglycemic Potential of Insulin

GUILLAUME KRAFT, MELANIE SCOTT, MARTA S. SMITH, BEN FARMER, DALE S. EDGERTON, ALAN D. CHERRINGTON
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1560-P
https://doi.org/10.2337/db23-1560-P
Published: 20 June 2023
View article titled, 1560-P: Combining Glucagon with Insulin Can Lessen the Hypoglycemic Potential of Insulin
Meeting Abstracts

1341-P: Dietary Fat and Fructose Impair Glucagon-Stimulated Liver Glucose Metabolism

DALE S. EDGERTON, GUILLAUME KRAFT, KATIE C. COATE, BEN FARMER, MARTA S. SMITH, MELANIE SCOTT, JON R. HASTINGS, MARY C. MOORE, ALAN D. CHERRINGTON
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1341-P
https://doi.org/10.2337/db22-1341-P
Published: 01 June 2022
View article titled, 1341-P: Dietary Fat and Fructose Impair Glucagon-Stimulated Liver Glucose Metabolism
Meeting Abstracts

367-OR: High-Fat and Fructose Feeding Severely Impairs Hepatic Glucose Effectiveness

DALE S. EDGERTON, GUILLAUME KRAFT, BEN FARMER, MELANIE SCOTT, MARTA S. SMITH, ALAN D. CHERRINGTON
Journal: Diabetes
Diabetes 2020;69(Supplement_1):367-OR
https://doi.org/10.2337/db20-367-OR
Published: 01 June 2020
View article titled, 367-OR: High-Fat and Fructose Feeding Severely Impairs Hepatic Glucose Effectiveness
Meeting Abstracts

371-P: Hypoglycemia in the Brain Is Required to Augment Counterregulatory Responses to Hypoglycemia when Liver Glycogen Levels Are Enhanced

SHANA O. WARNER, MARTA S. SMITH, BEN FARMER, JASON J. WINNICK
Journal: Diabetes
Diabetes 2019;68(Supplement_1):371-P
https://doi.org/10.2337/db19-371-P
Published: 01 June 2019
View article titled, 371-P: Hypoglycemia in the Brain Is Required to Augment Counterregulatory Responses to Hypoglycemia when Liver Glycogen Levels Are Enhanced
Meeting Abstracts

1848-P: Effect of Brain Glucagon Action on Hepatic Glucose Production

DALE S. EDGERTON, GUILLAUME KRAFT, BEN FARMER, MARTA S. SMITH, ALAN D. CHERRINGTON
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1848-P
https://doi.org/10.2337/db19-1848-P
Published: 01 June 2019
View article titled, 1848-P: Effect of Brain Glucagon Action on Hepatic Glucose Production
Meeting Abstracts

1849-P: Importance of Insulin’s Direct and Indirect Effects on Postprandial Hepatic Glucose Uptake

DALE S. EDGERTON, GUILLAUME KRAFT, BEN FARMER, MARTA S. SMITH, PHILLIP E. WILLIAMS, ALAN D. CHERRINGTON
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1849-P
https://doi.org/10.2337/db19-1849-P
Published: 01 June 2019
View article titled, 1849-P: Importance of Insulin’s Direct and Indirect Effects on Postprandial Hepatic Glucose Uptake
Journal Articles

Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison With GCK-MODY (MODY2)

Justin M. Gregory, T. Jordan Smith, James C. Slaughter, Holly R. Mason, Curtis C. Hughey, Marta S. Smith, Balamurugan Kandasamy, Siri Atma W. Greeley, Louis H. Philipson, Rochelle N. Naylor, Lisa R. Letourneau, Naji N. Abumrad, Alan D. Cherrington, Daniel J. Moore
Journal: Diabetes
Diabetes 2019;68(8):1565–1576
https://doi.org/10.2337/db19-0324
Published: 15 May 2019
View article titled, Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison With GCK-MODY (MODY2)
Open the PDF for Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison With GCK-MODY (MODY2) in another window
Includes: Supplementary data
Meeting Abstracts

Basal Oral Insulin Analog I338 Enhances Meal-Related Hepatic Glucose Disposal

MARY C. MOORE, ERICA NISHIMURA, CHRISTIAN L. BRAND, THOMAS KJELDSEN, PETER MADSEN, HANNE H. REFSGAARD, KARSTEN WASSERMANN, SANNE GRAM-NIELSEN, MARTA S. SMITH, L. MERKLE MOORE, BEN FARMER, JON R. HASTINGS, PHILLIP E. WILLIAMS, ALAN D. CHERRINGTON
Journal: Diabetes
Diabetes 2018;67(Supplement_1):347-OR
https://doi.org/10.2337/db18-347-OR
Published: 01 July 2018
View article titled, Basal Oral Insulin Analog I338 Enhances Meal-Related Hepatic Glucose Disposal
Meeting Abstracts

Incretin Hormone Release Does Not Involve Hepatic Portal Vein Glucose Sensors

DALE S. EDGERTON, GUILLAUME KRAFT, MARTA S. SMITH, L. MERKLE MOORE, BEN FARMER, HEATHER SARA, MELANIE SCOTT, MARY MOORE, MICHAEL A. NAUCK, ALAN D. CHERRINGTON
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1961-P
https://doi.org/10.2337/db18-1961-P
Published: 01 July 2018
View article titled, Incretin Hormone Release Does Not Involve Hepatic Portal Vein Glucose Sensors
Journal Articles

Morning Hyperinsulinemia Primes the Liver for Glucose Uptake and Glycogen Storage Later in the Day

Mary Courtney Moore, Marta S. Smith, Ben Farmer, Katie C. Coate, Guillaume Kraft, Masakazu Shiota, Phillip E. Williams, Alan D. Cherrington
Journal: Diabetes
Diabetes 2018;67(7):1237–1245
https://doi.org/10.2337/db17-0979
Published: 17 April 2018
View article titled, Morning Hyperinsulinemia Primes the Liver for Glucose Uptake and Glycogen Storage Later in the Day
Open the PDF for Morning Hyperinsulinemia Primes the Liver for Glucose Uptake and Glycogen Storage Later in the Day in another window
Journal Articles

Superior Glycemic Control With a Glucose-Responsive Insulin Analog: Hepatic and Nonhepatic Impacts

Mary Courtney Moore, David E. Kelley, Raul C. Camacho, Peter Zafian, Tian Ye, Songnian Lin, Niels C. Kaarsholm, Ravi Nargund, Terri M. Kelly, Margaret Van Heek, Stephen F. Previs, Christopher Moyes, Marta S. Smith, Ben Farmer, Phil Williams, Alan D. Cherrington
Journal: Diabetes
Diabetes 2018;67(6):1173–1181
https://doi.org/10.2337/db18-0099
Published: 14 March 2018
View article titled, Superior Glycemic Control With a Glucose-Responsive Insulin Analog: Hepatic and Nonhepatic Impacts
Open the PDF for Superior Glycemic Control With a Glucose-Responsive Insulin Analog: Hepatic and Nonhepatic Impacts in another window
Includes: Supplementary data
Journal Articles

Priming Effect of a Morning Meal on Hepatic Glucose Disposition Later in the Day

Mary Courtney Moore, Marta S. Smith, Ben Farmer, Guillaume Kraft, Masakazu Shiota, Phillip E. Williams, Alan D. Cherrington
Journal: Diabetes
Diabetes 2017;66(5):1136–1145
https://doi.org/10.2337/db16-1308
Published: 07 February 2017
View article titled, Priming Effect of a Morning Meal on Hepatic Glucose Disposition Later in the Day
Open the PDF for Priming Effect of a Morning Meal on Hepatic Glucose Disposition Later in the Day in another window
Journal Articles

Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes

Justin M. Gregory, Guillaume Kraft, Melanie F. Scott, Doss W. Neal, Ben Farmer, Marta S. Smith, Jon R. Hastings, Eric J. Allen, E. Patrick Donahue, Noelia Rivera, Jason J. Winnick, Dale S. Edgerton, Erica Nishimura, Christian Fledelius, Christian L. Brand, Alan D. Cherrington
Journal: Diabetes
Diabetes 2015;64(10):3439–3451
https://doi.org/10.2337/db15-0071
Published: 17 June 2015
View article titled, Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes
Open the PDF for Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes in another window
Journal Articles

Novel PEGylated Basal Insulin LY2605541 Has a Preferential Hepatic Effect on Glucose Metabolism

Mary Courtney Moore, Marta S. Smith, Vikram P. Sinha, John M. Beals, M. Dodson Michael, Scott J. Jacober, Alan D. Cherrington
Journal: Diabetes
Diabetes 2014;63(2):494–504
https://doi.org/10.2337/db13-0826
Published: 16 January 2014
View article titled, Novel PEGylated Basal Insulin LY2605541 Has a Preferential Hepatic Effect on Glucose Metabolism
Open the PDF for Novel PEGylated Basal Insulin LY2605541 Has a Preferential Hepatic Effect on Glucose Metabolism in another window
Includes: Supplementary data
Journal Articles

Hepatic Glucose Metabolism in Late Pregnancy: Normal Versus High-Fat and -Fructose Diet

Katie C. Coate, Marta S. Smith, Masakazu Shiota, Jose M. Irimia, Peter J. Roach, Ben Farmer, Phillip E. Williams, Mary Courtney Moore
Journal: Diabetes
Diabetes 2013;62(3):753–761
https://doi.org/10.2337/db12-0875
Published: 14 February 2013
View article titled, Hepatic Glucose Metabolism in Late Pregnancy: <subtitle>Normal Versus High-Fat and -Fructose Diet</subtitle>
Open the PDF for Hepatic Glucose Metabolism in Late Pregnancy: <subtitle>Normal Versus High-Fat and -Fructose Diet</subtitle> in another window
Journal Articles

Portal Vein Glucose Entry Triggers a Coordinated Cellular Response That Potentiates Hepatic Glucose Uptake and Storage in Normal but Not High-Fat/High-Fructose–Fed Dogs

Katie C. Coate, Guillaume Kraft, Jose M. Irimia, Marta S. Smith, Ben Farmer, Doss W. Neal, Peter J. Roach, Masakazu Shiota, Alan D. Cherrington
Journal: Diabetes
Diabetes 2013;62(2):392–400
https://doi.org/10.2337/db12-0417
Published: 17 January 2013
View article titled, Portal Vein Glucose Entry Triggers a Coordinated Cellular Response That Potentiates Hepatic Glucose Uptake and Storage in Normal but Not High-Fat/High-Fructose–Fed Dogs
Open the PDF for Portal Vein Glucose Entry Triggers a Coordinated Cellular Response That Potentiates Hepatic Glucose Uptake and Storage in Normal but Not High-Fat/High-Fructose–Fed Dogs in another window
Includes: Supplementary data
Journal Articles

Interaction Between the Central and Peripheral Effects of Insulin in Controlling Hepatic Glucose Metabolism in the Conscious Dog

Christopher J. Ramnanan, Guillaume Kraft, Marta S. Smith, Ben Farmer, Doss Neal, Phillip E. Williams, Margaret Lautz, Tiffany Farmer, E. Patrick Donahue, Alan D. Cherrington, Dale S. Edgerton
Journal: Diabetes
Diabetes 2013;62(1):74–84
https://doi.org/10.2337/db12-0148
Published: 13 December 2012
View article titled, Interaction Between the Central and Peripheral Effects of Insulin in Controlling Hepatic Glucose Metabolism in the Conscious Dog
Open the PDF for Interaction Between the Central and Peripheral Effects of Insulin in Controlling Hepatic Glucose Metabolism in the Conscious Dog in another window
Includes: Supplementary data