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Journal Articles

TBK1-mTOR Signaling Attenuates Obesity-Linked Hyperglycemia and Insulin Resistance

Cagri Bodur, Dubek Kazyken, Kezhen Huang, Aaron Seth Tooley, Kae Won Cho, Tammy M. Barnes, Carey N. Lumeng, Martin G. Myers, Jr., Diane C. Fingar
Journal: Diabetes
Diabetes 2022;71(11):2297–2312
https://doi.org/10.2337/db22-0256
Published: 19 August 2022
View article titled, TBK1-mTOR Signaling Attenuates Obesity-Linked Hyperglycemia and Insulin Resistance
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Meeting Abstracts

153-OR: Ventromedial Hypothalamic Nucleus Controls Glucose Metabolism through Adipose Tissue Lipolysis

ALISON AFFINATI, JONATHAN FLAK, NANDAN KODUR, ABDULLAH HASHSHAM, ABIGAIL J. TOMLINSON, NADEJDA BOZADJIEVA KRAMER, CHIEN LI, MARTIN G. MYERS, JR.
Journal: Diabetes
Diabetes 2022;71(Supplement_1):153-OR
https://doi.org/10.2337/db22-153-OR
Published: 01 June 2022
View article titled, 153-OR: Ventromedial Hypothalamic Nucleus Controls Glucose Metabolism through Adipose Tissue Lipolysis
Journal Articles

Deletion of the Brain-Specific α and δ Isoforms of Adapter Protein SH2B1 Protects Mice From Obesity

Jessica L. Cote, Lawrence S. Argetsinger, Anabel Flores, Alan C. Rupp, Joel M. Cline, Lauren C. DeSantis, Alexander H. Bedard, Devika P. Bagchi, Paul B. Vander, Abrielle M. Cacciaglia, Erik S. Clutter, Gowri Chandrashekar, Ormond A. MacDougald, Martin G. Myers, Jr., Christin Carter-Su
Journal: Diabetes
Diabetes 2021;70(2):400–414
https://doi.org/10.2337/db20-0687
Published: 19 November 2020
View article titled, Deletion of the Brain-Specific α and δ Isoforms of Adapter Protein SH2B1 Protects Mice From Obesity
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Meeting Abstracts

1760-P: Brain Sh2b1 Protects against Obesity and Insulin Resistance through Multiple Hypothalamic Neural Circuits

YUAN LI, MIN-HYUN KIM, LIN JIANG, MARTIN G. MYERS, JR., LIANGYOU RUI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1760-P
https://doi.org/10.2337/db20-1760-P
Published: 01 June 2020
View article titled, 1760-P: Brain Sh2b1 Protects against Obesity and Insulin Resistance through Multiple Hypothalamic Neural Circuits
Meeting Abstracts

1778-P: A Single Cell Map of Metabolically Regulated Neurons in the Ventromedial Hypothalamic Nucleus

ALAN RUPP, ALISON AFFINATI, MARTIN G. MYERS, JR.
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1778-P
https://doi.org/10.2337/db20-1778-P
Published: 01 June 2020
View article titled, 1778-P: A Single Cell Map of Metabolically Regulated Neurons in the Ventromedial Hypothalamic Nucleus
Meeting Abstracts

211-OR: Hypothalamic Slug Couples Overnutrition States to Epigenetic Reprogramming of Leptin Neural Circuits, Obesity, and Type 2 Diabetes

MIN-HYUN KIM, LIN JIANG, MARTIN G. MYERS, JR., LIANGYOU RUI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):211-OR
https://doi.org/10.2337/db20-211-OR
Published: 01 June 2020
View article titled, 211-OR: Hypothalamic Slug Couples Overnutrition States to Epigenetic Reprogramming of Leptin Neural Circuits, Obesity, and Type 2 Diabetes
Meeting Abstracts

215-OR: Silencing CCKBR Containing Neurons in the VMN Restrains Hepatic Glucose Production to Ameliorate Diabetes in Mice

ALISON AFFINATI, JONATHAN FLAK, NADEJDA BOZADJIEVA, NANDAN KODUR, CORENTIN M. CRAS-MÉNEUR, DARLEEN A. SANDOVAL, MARTIN G. MYERS, JR.
Journal: Diabetes
Diabetes 2020;69(Supplement_1):215-OR
https://doi.org/10.2337/db20-215-OR
Published: 01 June 2020
View article titled, 215-OR: Silencing CCKBR Containing Neurons in the VMN Restrains Hepatic Glucose Production to Ameliorate Diabetes in Mice
Meeting Abstracts

196-LB: Synergetic and Distinct Roles in the Control of Food Intake and Energy Balance for Subpopulations of NTS Neurons

WENWEN C. CHENG, ERMELINDA NDOKA, BASMA MAERZ, KAREN J. ROELOFS, CHRISTOPHER J. RHODES, RANDY J. SEELEY, DARLEEN A. SANDOVAL, DAVID OLSON, MARTIN G. MYERS, JR.
Journal: Diabetes
Diabetes 2020;69(Supplement_1):196-LB
https://doi.org/10.2337/db20-196-LB
Published: 01 June 2020
View article titled, 196-LB: Synergetic and Distinct Roles in the Control of Food Intake and Energy Balance for Subpopulations of NTS Neurons
Journal Articles

Crucial Role of the SH2B1 PH Domain for the Control of Energy Balance

Anabel Flores, Lawrence S. Argetsinger, Lukas K.J. Stadler, Alvaro E. Malaga, Paul B. Vander, Lauren C. DeSantis, Ray M. Joe, Joel M. Cline, Julia M. Keogh, Elana Henning, Ines Barroso, Edson Mendes de Oliveira, Gowri Chandrashekar, Erik S. Clutter, Yixin Hu, Jeanne Stuckey, I. Sadaf Farooqi, Martin G. Myers, Jr., Christin Carter-Su
Journal: Diabetes
Diabetes 2019;68(11):2049–2062
https://doi.org/10.2337/db19-0608
Published: 22 August 2019
View article titled, Crucial Role of the SH2B1 PH Domain for the Control of Energy Balance
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Includes: Supplementary data
Journal Articles

Diabetes Takes New Steps to Increase Transparency and Reproducibility

Martin G. Myers, Jr.
Journal: Diabetes
Diabetes 2019;68(4):681–682
https://doi.org/10.2337/dbi19-0008
Published: 11 February 2019
View article titled, <em>Diabetes</em> Takes New Steps to Increase Transparency and Reproducibility
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Journal Articles

A Call for Improved Reporting of Human Islet Characteristics in Research Articles

Vincent Poitout, Leslie S. Satin, Steven E. Kahn, Doris A. Stoffers, Piero Marchetti, Maureen Gannon, C. Bruce Verchere, Kevan C. Herold, Martin G. Myers, Jr., Sally M. Marshall
Journal: Diabetes
Diabetes 2019;68(2):239–240
https://doi.org/10.2337/dbi18-0055
Published: 14 December 2018
View article titled, A Call for Improved Reporting of Human Islet Characteristics in Research Articles
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Meeting Abstracts

Identification of VmnCckbr Neurons as Crucial Mediators of the Counterregulatory Response to Hypoglycemia

JONATHAN N. FLAK, AHSAN ANSARI, PAUL SABATINI, PAULETTE B. GOFORTH, CHIEN LI, DARLEEN A. SANDOVAL, DAVID OLSON, MARTIN G. MYERS, JR.
Journal: Diabetes
Diabetes 2018;67(Supplement_1):202-OR
https://doi.org/10.2337/db18-202-OR
Published: 01 July 2018
View article titled, Identification of VmnCckbr Neurons as Crucial Mediators of the Counterregulatory Response to Hypoglycemia
Journal Articles

Defining the Transcriptional Targets of Leptin Reveals a Role for Atf3 in Leptin Action

Margaret B. Allison, Warren Pan, Alexander MacKenzie, Christa Patterson, Kimi Shah, Tammy Barnes, Wenwen Cheng, Alan Rupp, David P. Olson, Martin G. Myers, Jr.
Journal: Diabetes
Diabetes 2018;67(6):1093–1104
https://doi.org/10.2337/db17-1395
Published: 13 March 2018
View article titled, Defining the Transcriptional Targets of Leptin Reveals a Role for <em>Atf3</em> in Leptin Action
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Includes: Supplementary data
Journal Articles

A Few Words of Introduction From Your New Diabetes Editorial Board

Martin G. Myers, Jr.
Journal: Diabetes
Diabetes 2017;66(1):3–4
https://doi.org/10.2337/db16-1301
Published: 10 December 2016
View article titled, A Few Words of Introduction From Your New <em>Diabetes</em> Editorial Board
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Journal Articles

The Brain–to–Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions

Wilfredo Rosario, Inderroop Singh, Arnaud Wautlet, Christa Patterson, Jonathan Flak, Thomas C. Becker, Almas Ali, Natalia Tamarina, Louis H. Philipson, Lynn W. Enquist, Martin G. Myers, Jr., Christopher J. Rhodes
Journal: Diabetes
Diabetes 2016;65(9):2711–2723
https://doi.org/10.2337/db15-0629
Published: 12 April 2016
View article titled, The Brain–to–Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions
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Includes: Supplementary data
Journal Articles

Euglycemia Restoration by Central Leptin in Type 1 Diabetes Requires STAT3 Signaling but Not Fast-Acting Neurotransmitter Release

Yuanzhong Xu, Jeffrey T. Chang, Martin G. Myers, Jr., Yong Xu, Qingchun Tong
Journal: Diabetes
Diabetes 2016;65(4):1040–1049
https://doi.org/10.2337/db15-1160
Published: 28 January 2016
View article titled, Euglycemia Restoration by Central Leptin in Type 1 Diabetes Requires STAT3 Signaling but Not Fast-Acting Neurotransmitter Release
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Includes: Supplementary data
Journal Articles

Outstanding Scientific Achievement Award Lecture 2010: Deconstructing Leptin: From Signals to Circuits

Martin G. Myers, Jr
Journal: Diabetes
Diabetes 2010;59(11):2708–2714
https://doi.org/10.2337/db10-1118
Published: 01 November 2010
View article titled, Outstanding Scientific Achievement Award Lecture 2010: Deconstructing Leptin: From Signals to Circuits
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Journal Articles

Conditional Gene Targeting in Mouse Pancreatic β-Cells: Analysis of Ectopic Cre Transgene Expression in the Brain

Barton Wicksteed, Marcela Brissova, Wenbo Yan, Darren M. Opland, Jennifer L. Plank, Rachel B. Reinert, Lorna M. Dickson, Natalia A. Tamarina, Louis H. Philipson, Alena Shostak, Ernesto Bernal-Mizrachi, Lynda Elghazi, Michael W. Roe, Patricia A. Labosky, Martin G. Myers, Jr., Maureen Gannon, Alvin C. Powers, Peter J. Dempsey
Journal: Diabetes
Diabetes 2010;59(12):3090–3098
https://doi.org/10.2337/db10-0624
Published: 29 August 2010
View article titled, Conditional Gene Targeting in Mouse Pancreatic β-Cells: <subtitle>Analysis of Ectopic Cre Transgene Expression in the Brain</subtitle>
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Includes: Supplementary data
Journal Articles

Functional Role of Suppressor of Cytokine Signaling 3 Upregulation in Hypothalamic Leptin Resistance and Long-Term Energy Homeostasis

Alison S. Reed, Elizabeth K. Unger, Louise E. Olofsson, Merisa L. Piper, Martin G. Myers, Jr, Allison W. Xu
Journal: Diabetes
Diabetes 2010;59(4):894–906
https://doi.org/10.2337/db09-1024
Published: 12 January 2010
View article titled, Functional Role of Suppressor of Cytokine Signaling 3 Upregulation in Hypothalamic Leptin Resistance and Long-Term Energy Homeostasis
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Includes: Supplementary data
Journal Articles

Insufficiency of Janus Kinase 2–Autonomous Leptin Receptor Signals for Most Physiologic Leptin Actions

Scott Robertson, Ryoko Ishida-Takahashi, Isao Tawara, Jiang Hu, Christa M. Patterson, Justin C. Jones, Rohit N. Kulkarni, Martin G. Myers, Jr
Journal: Diabetes
Diabetes 2010;59(4):782–790
https://doi.org/10.2337/db09-1556
Published: 12 January 2010
View article titled, Insufficiency of Janus Kinase 2–Autonomous Leptin Receptor Signals for Most Physiologic Leptin Actions
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Includes: Supplementary data