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Mauricio D. Dorfman
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Meeting Abstracts

1541-P: The Role of Microglia Estrogen Receptor Alpha Signaling in Obesity Pathogenesis

INMACULADA VELASCO AGUAYO, TRISTAN Z. JAFARI, JEREMY FREY, OLIVIA D. SANTIAGO, JOSHUA THALER, MAURICIO D. DORFMAN
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1541-P
https://doi.org/10.2337/db24-1541-P
Published: 14 June 2024
View article titled, 1541-P: The Role of Microglia Estrogen Receptor Alpha Signaling in Obesity Pathogenesis
Journal Articles

Prostaglandin PGE2 Receptor EP4 Regulates Microglial Phagocytosis and Increases Susceptibility to Diet-Induced Obesity

Anzela Niraula, Rachael D. Fasnacht, Kelly M. Ness, Jeremy M. Frey, Sophia A. Cuschieri, Mauricio D. Dorfman, Joshua P. Thaler
Journal: Diabetes
Diabetes 2023;72(2):233–244
https://doi.org/10.2337/db21-1072
Published: 01 November 2022
View article titled, Prostaglandin PGE2 Receptor EP4 Regulates Microglial Phagocytosis and Increases Susceptibility to Diet-Induced Obesity
Open the PDF for Prostaglandin PGE2 Receptor EP4 Regulates Microglial Phagocytosis and Increases Susceptibility to Diet-Induced Obesity in another window
Meeting Abstracts

152-OR: Evidence Linking Loss of Hypothalamic Perineuronal Nets to Obesity Pathogenesis

KIMBERLY M. ALONGE, MAURICIO D. DORFMAN, JARRAD M. SCARLETT, SUSAN J. MELHORN, YUANCHAO YE, SHANNON J.W. HU, KENDRA L. FRANCIS, AARUN HENDRICKSON, KATHERINE CUI, GREGORY J. MORTON, ELLEN SCHUR, JOSHUA THALER, MICHAEL W. SCHWARTZ
Journal: Diabetes
Diabetes 2022;71(Supplement_1):152-OR
https://doi.org/10.2337/db22-152-OR
Published: 01 June 2022
View article titled, 152-OR: Evidence Linking Loss of Hypothalamic Perineuronal Nets to Obesity Pathogenesis
Meeting Abstracts

212-OR: Testosterone Deficiency Increases Hypothalamic Gliosis and Metabolic Risk

MAURICIO D. DORFMAN, JEREMY FREY, KELLY M. NESS, ANZELA NIRAULA, JENNY E. KANTER, KARIN BORNFELDT, KATYA RUBINOW, ELLEN SCHUR, JOSHUA THALER
Journal: Diabetes
Diabetes 2020;69(Supplement_1):212-OR
https://doi.org/10.2337/db20-212-OR
Published: 01 June 2020
View article titled, 212-OR: Testosterone Deficiency Increases Hypothalamic Gliosis and Metabolic Risk
Meeting Abstracts

1769-P: Microglial Activation and Inactivation via Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) Alters Peripheral Glucose Homeostasis

KELLY M. NESS, JOHN DOUGLASS, MARTIN VALDEARCOS-CONTRERAS, SR., MAURICIO D. DORFMAN, ANZELA NIRAULA, SUNEIL K. KOLIWAD, JOSHUA THALER
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1769-P
https://doi.org/10.2337/db20-1769-P
Published: 01 June 2020
View article titled, 1769-P: Microglial Activation and Inactivation via Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) Alters Peripheral Glucose Homeostasis
Meeting Abstracts

1759-P: Prostaglandin PGE2 Receptor EP4 Signaling Deficiency in Microglia Reduces Weight Gain with Transient Glucose Improvements in Diet-Induced Obesity

ANZELA NIRAULA, RACHAEL FASNACHT, KELLY M. NESS, JEREMY FREY, MAURICIO D. DORFMAN, JOSHUA THALER
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1759-P
https://doi.org/10.2337/db20-1759-P
Published: 01 June 2020
View article titled, 1759-P: Prostaglandin PGE2 Receptor EP4 Signaling Deficiency in Microglia Reduces Weight Gain with Transient Glucose Improvements in Diet-Induced Obesity
Journal Articles

Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity

Mauricio D. Dorfman, Jordan E. Krull, Jarrad M. Scarlett, Stephan J. Guyenet, Mini P. Sajan, Vincent Damian, Hong T. Nguyen, Michael Leitges, Gregory J. Morton, Robert V. Farese, Michael W. Schwartz, Joshua P. Thaler
Journal: Diabetes
Diabetes 2017;66(4):920–934
https://doi.org/10.2337/db16-0482
Published: 10 January 2017
View article titled, Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity
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Includes: Supplementary data
Journal Articles

Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia

Thomas H. Meek, Mauricio D. Dorfman, Miles E. Matsen, Jonathan D. Fischer, Alexis Cubelo, Monica R. Kumar, Gerald J. Taborsky, Jr., Gregory J. Morton
Journal: Diabetes
Diabetes 2015;64(7):2376–2387
https://doi.org/10.2337/db14-1562
Published: 29 January 2015
View article titled, Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia
Open the PDF for Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia in another window
Journal Articles

Hypothalamic Inflammation: Marker or Mechanism of Obesity Pathogenesis?

Joshua P. Thaler, Stephan J. Guyenet, Mauricio D. Dorfman, Brent E. Wisse, Michael W. Schwartz
Journal: Diabetes
Diabetes 2013;62(8):2629–2634
https://doi.org/10.2337/db12-1605
Published: 17 July 2013
View article titled, Hypothalamic Inflammation: Marker or Mechanism of Obesity Pathogenesis?
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