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Michael D. Dennis
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Journal Articles

Podocyte-Specific Expression of the Stress Response Protein REDD1 Is Necessary for Diabetes-Induced Podocytopenia

Free
Siddharth Sunilkumar, Esma I. Yerlikaya, Allyson L. Toro, Han Chen, Yandong Zhou, Donald L. Gill, Scot R. Kimball, Michael D. Dennis
Journal: Diabetes
Diabetes 2025;74(3):398–408
https://doi.org/10.2337/db24-0533
Published: 25 September 2024
View articletitled, Podocyte-Specific Expression of the Stress Response Protein REDD1 Is Necessary for Diabetes-Induced Podocytopenia
Open the PDF for Podocyte-Specific Expression of the Stress Response Protein REDD1 Is Necessary for Diabetes-Induced Podocytopenia in another window
Journal Articles

REDD1 Is a Promising Therapeutic Target to Combat the Development of Diabetes Complications: A Report on Research Supported by Pathway to Stop Diabetes

Free
Siddharth Sunilkumar, Michael D. Dennis
Journal: Diabetes
Diabetes 2024;73(10):1553–1562
https://doi.org/10.2337/dbi24-0013
Published: 08 July 2024
View articletitled, REDD1 Is a Promising Therapeutic Target to Combat the Development of Diabetes Complications: A Report on Research Supported by Pathway to Stop Diabetes
Open the PDF for REDD1 Is a Promising Therapeutic Target to Combat the Development of Diabetes Complications: A Report on Research Supported by Pathway to Stop Diabetes in another window
Meeting Abstracts

500-P: Disruption of REDD1 Protein Allostery as a Therapeutic for Diabetic Retinopathy

Free
MICHAEL D. DENNIS, SIDDHARTH SUNILKUMAR, WILLIAM P. MILLER, CONGZHOU M. SHA, NIKOLAY V. DOKHOLYAN
Journal: Diabetes
Diabetes 2024;73(Supplement_1):500-P
https://doi.org/10.2337/db24-500-P
Published: 14 June 2024
View articletitled, 500-P: Disruption of REDD1 Protein Allostery as a Therapeutic for Diabetic Retinopathy
Meeting Abstracts

318-OR: Podocyte-Specific Expression of REDD1 Promotes Altered Glomerular Pathology and Renal Function Deficits in a Rodent Model of Diabetic Nephropathy

Free
SIDDHARTH SUNILKUMAR, ALLYSON TORO, ESMA I. YERLIKAYA, MICHAEL D. DENNIS
Journal: Diabetes
Diabetes 2024;73(Supplement_1):318-OR
https://doi.org/10.2337/db24-318-OR
Published: 14 June 2024
View articletitled, 318-OR: Podocyte-Specific Expression of REDD1 Promotes Altered Glomerular Pathology and Renal Function Deficits in a Rodent Model of Diabetic Nephropathy
Journal Articles

Activation of Disulfide Redox Switch in REDD1 Promotes Oxidative Stress Under Hyperglycemic Conditions

Free
William P. Miller, Congzhou M. Sha, Siddharth Sunilkumar, Allyson L. Toro, Ashley M. VanCleave, Scot R. Kimball, Nikolay V. Dokholyan, Michael D. Dennis
Journal: Diabetes
Diabetes 2022;71(12):2764–2776
https://doi.org/10.2337/db22-0355
Published: 28 September 2022
View articletitled, Activation of Disulfide Redox Switch in REDD1 Promotes Oxidative Stress Under Hyperglycemic Conditions
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Journal Articles

REDD1 Ablation Attenuates the Development of Renal Complications in Diabetic Mice

Free
Siddharth Sunilkumar, Esma I. Yerlikaya, Allyson L. Toro, William P. Miller, Han Chen, Kebin Hu, Scot R. Kimball, Michael D. Dennis
Journal: Diabetes
Diabetes 2022;71(11):2412–2425
https://doi.org/10.2337/db22-0402
Published: 19 August 2022
View articletitled, REDD1 Ablation Attenuates the Development of Renal Complications in Diabetic Mice
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Journal Articles

Müller Glial Expression of REDD1 Is Required for Retinal Neurodegeneration and Visual Dysfunction in Diabetic Mice

Free
William P. Miller, Allyson L. Toro, Siddharth Sunilkumar, Shaunaci A. Stevens, Ashley M. VanCleave, David L. Williamson, Alistair J. Barber, Michael D. Dennis
Journal: Diabetes
Diabetes 2022;71(5):1051–1062
https://doi.org/10.2337/db21-0853
Published: 15 February 2022
View articletitled, Müller Glial Expression of REDD1 Is Required for Retinal Neurodegeneration and Visual Dysfunction in Diabetic Mice
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Meeting Abstracts

433-P: Hyperglycemia-Induced Oxidative Stress Prevents REDD1 Degradation by Chaperone-Mediated Autophagy

Free
WILLIAM P. MILLER, ALLYSON TORO, SIDDHARTH SUNILKUMAR, JOSEPH GIORDANO, MICHAEL D. DENNIS
Journal: Diabetes
Diabetes 2021;70(Supplement_1):433-P
https://doi.org/10.2337/db21-433-P
Published: 01 June 2021
View articletitled, 433-P: Hyperglycemia-Induced Oxidative Stress Prevents REDD1 Degradation by Chaperone-Mediated Autophagy
Meeting Abstracts

329-OR: REDD1 Suppresses the Retinal Antioxidant Response to Diabetes by Destabilizing Nrf2

Free
WILLIAM P. MILLER, ALLYSON TORO, JOSEPH GIORDANO, MICHAEL D. DENNIS
Journal: Diabetes
Diabetes 2020;69(Supplement_1):329-OR
https://doi.org/10.2337/db20-329-OR
Published: 01 June 2020
View articletitled, 329-OR: REDD1 Suppresses the Retinal Antioxidant Response to Diabetes by Destabilizing Nrf2
Meeting Abstracts

593-P: Diabetes Enhances Translation of the mRNA Encoding CD40 in Müller Glia to Promote Retinal Inflammation

Free
SADIE K. DIERSCHKE, ALLYSON TORO, WILLIAM P. MILLER, MICHAEL D. DENNIS
Journal: Diabetes
Diabetes 2019;68(Supplement_1):593-P
https://doi.org/10.2337/db19-593-P
Published: 01 June 2019
View articletitled, 593-P: Diabetes Enhances Translation of the mRNA Encoding CD40 in Müller Glia to Promote Retinal Inflammation
Meeting Abstracts

Angiotensin-(1-7) Attenuates Protein O-GlcNAcylation in the Retina of Mice Fed a High-Fat Diet

Free
SADIE DIERSCHKE, AMY C. ARNOLD, ALISTAIR J. BARBER, MICHAEL D. DENNIS
Journal: Diabetes
Diabetes 2018;67(Supplement_1):592-P
https://doi.org/10.2337/db18-592-P
Published: 01 July 2018
View articletitled, Angiotensin-(1-7) Attenuates Protein O-GlcNAcylation in the Retina of Mice Fed a High-Fat Diet
Meeting Abstracts

High-Fat Diet/Palmitate–Induced ER Stress Promotes Protein O-GlcNAcylation in Retina and Retinal Muller Cells

Free
WEIWEI DAI, ALLYSON TORO, SADIE K. DIERSCHKE, MICHAEL D. DENNIS
Journal: Diabetes
Diabetes 2018;67(Supplement_1):607-P
https://doi.org/10.2337/db18-607-P
Published: 01 July 2018
View articletitled, High-Fat Diet/Palmitate–Induced ER Stress Promotes Protein O-GlcNAcylation in Retina and Retinal Muller Cells
Meeting Abstracts

Deletion of REDD1 Prevents Hyperglycemia-Induced Reactive Oxygen Species Accumulation and Retinal Cell Death

Free
WILLIAM P. MILLER, ALLYSON TORO, MICHAEL D. DENNIS
Journal: Diabetes
Diabetes 2018;67(Supplement_1):242-OR
https://doi.org/10.2337/db18-242-OR
Published: 01 July 2018
View articletitled, Deletion of REDD1 Prevents Hyperglycemia-Induced Reactive Oxygen Species Accumulation and Retinal Cell Death
Journal Articles

Deletion of the Akt/mTORC1 Repressor REDD1 Prevents Visual Dysfunction in a Rodent Model of Type 1 Diabetes

Free
William P. Miller, Chen Yang, Maria L. Mihailescu, Joshua A. Moore, Weiwei Dai, Alistair J. Barber, Michael D. Dennis
Journal: Diabetes
Diabetes 2018;67(1):110–119
https://doi.org/10.2337/db17-0728
Published: 26 October 2017
View articletitled, Deletion of the Akt/mTORC1 Repressor REDD1 Prevents Visual Dysfunction in a Rodent Model of Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Hyperglycemia Mediates a Shift From Cap-Dependent to Cap-Independent Translation Via a 4E-BP1–Dependent Mechanism

Open Access
Michael D. Dennis, Jeffrey S. Shenberger, Bruce A. Stanley, Scot R. Kimball, Leonard S. Jefferson
Journal: Diabetes
Diabetes 2013;62(7):2204–2214
https://doi.org/10.2337/db12-1453
Published: 14 June 2013
View articletitled, Hyperglycemia Mediates a Shift From Cap-Dependent to Cap-Independent Translation Via a 4E-BP1–Dependent Mechanism
Open the PDF for Hyperglycemia Mediates a Shift From Cap-Dependent to Cap-Independent Translation Via a 4E-BP1–Dependent Mechanism in another window
Includes: Supplementary data