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Journal Articles

Pancreatic β cell TRAPδ deficiency reduces insulin production but improves insulin sensitivity

Jiyun Guo, M.M., Yanshu Yang, M.M., Ning Xu, M.M., Xin Li, M.D., Ying Yang, M.D., Wenli Feng, Ph.D., Yuanyuan Ye, M.M., Xiaoxi Xu, M.D., Jingqiu Cui, M.D., Ming Liu, M.D., Ph.D., Yumeng Huang, M.D.

Diabetes db230984

https://doi.org/10.2337/db23-0984

Published: 21 August 2024

View article titled, Pancreatic β cell TRAPδ deficiency reduces insulin production but improves insulin sensitivity

Meeting Abstracts

1745-P: IPO13 Maintains Glucose Homeostasis by Regulating Insulin Secretion and α-Cell Expansion

QINYING ZHAO, YING YANG, SHUHUI JI, YUANSI CHEN, WENLI FENG, MING LIU

Diabetes 2024;73(Supplement_1):1745-P

https://doi.org/10.2337/db24-1745-P

Published: 14 June 2024

View article titled, 1745-P: IPO13 Maintains Glucose Homeostasis by Regulating Insulin Secretion and α-Cell Expansion

Meeting Abstracts

1869-LB: Efficacy and Safety of iGlarLixi vs. IDegAsp in Chinese People with Type 2 Diabetes (T2D) Suboptimally Controlled with Oral Antidiabetic Drug(s) (OAD)—The SoliD Randomized Controlled Trial

MING LIU, WEIJUN GU, LI CHEN, YANBING LI, HONGYU KUANG, JIANLING DU, AGUSTINA ALVAREZ, FELIPE LAUAND, SR., ELISABETH SOUHAMI, JIEWEN ZHANG, WEIYA XU, QIN DU, YIMING MU

Diabetes 2024;73(Supplement_1):1869-LB

https://doi.org/10.2337/db24-1869-LB

Published: 14 June 2024

View article titled, 1869-LB: Efficacy and Safety of iGlarLixi vs. IDegAsp in Chinese People with Type 2 Diabetes (T2D) Suboptimally Controlled with Oral Antidiabetic Drug(s) (OAD)—The SoliD Randomized Controlled Trial

Meeting Abstracts

1743-P: STING Mediates Glucose-Induced Insulin Secretion through Pax6

ZIYUE ZHANG, JINGTING QIAO, YANG LIU, MING LIU

Diabetes 2024;73(Supplement_1):1743-P

https://doi.org/10.2337/db24-1743-P

Published: 14 June 2024

View article titled, 1743-P: STING Mediates Glucose-Induced Insulin Secretion through Pax6

Journal Articles

Foxj3 Regulates Thermogenesis of Brown and Beige Fat Via Induction of PGC-1α

Jincan Huang, Yujie Zhang, Xuenan Zhou, Jiani Song, Yueyao Feng, Tongtong Qiu, Sufang Sheng, Menglin Zhang, Xi Zhang, Jingran Hao, Lei Zhang, Yinliang Zhang, Xiaorong Li, Ming Liu, Yongsheng Chang

Diabetes 2024;73(2):178–196

https://doi.org/10.2337/db23-0454

Published: 08 November 2023

View article titled, Foxj3 Regulates Thermogenesis of Brown and Beige Fat Via Induction of PGC-1α

Meeting Abstracts

236-OR: Pancreatic ß-Cell TRAPδ Deficiency Reduces Insulin Production but Improves Insulin Sensitivity

JIYUN GUO, YANSHU YANG, NING XU, YING YANG, WENLI FENG, YUANYUAN YE, XIN LI, XIAOXI XU, JINGQIU CUI, YUMENG HUANG, MING LIU

Diabetes 2023;72(Supplement_1):236-OR

https://doi.org/10.2337/db23-236-OR

Published: 20 June 2023

View article titled, 236-OR: Pancreatic ß-Cell TRAPδ Deficiency Reduces Insulin Production but Improves Insulin Sensitivity

Meeting Abstracts

503-P: Distinct Effects of a Novel GCK-MODY Mutation on Lipid Profiles and Diabetic Complications

YADI HUANG, YUXIN FAN, XIN LI, SHUHUI JI, SHANSHAN CHEN, JINGQIU CUI, WENLI FENG, HUA SHU, MING LIU

Diabetes 2023;72(Supplement_1):503-P

https://doi.org/10.2337/db23-503-P

Published: 20 June 2023

View article titled, 503-P: Distinct Effects of a Novel GCK-MODY Mutation on Lipid Profiles and Diabetic Complications

Meeting Abstracts

1752-P: The Role of Translocon-Associated Protein Subunit γ in Insulin Biosynthesis and Glucose Homeostasis

NING XU, XIAOXI XU, JINGXIN HU, JIYUN GUO, JINGQIU CUI, MING LIU, WENLI FENG, XIN LI

Diabetes 2023;72(Supplement_1):1752-P

https://doi.org/10.2337/db23-1752-P

Published: 20 June 2023

View article titled, 1752-P: The Role of Translocon-Associated Protein Subunit γ in Insulin Biosynthesis and Glucose Homeostasis

Meeting Abstracts

778-P: Efficacy and Safety of Supaglutide as Add-on to Metformin in Patients with Type 2 Diabetes

Diabetes 2023;72(Supplement_1):778-P

https://doi.org/10.2337/db23-778-P

Published: 20 June 2023

View article titled, 778-P: Efficacy and Safety of Supaglutide as Add-on to Metformin in Patients with Type 2 Diabetes

Journal Articles

Glucose-Activated Switch Regulating Insulin Analog Secretion Enables Long-term Precise Glucose Control in Mice With Type 1 Diabetes

Lifang Xie, Wanling Lu, Yanhan Zhang, Lu Deng, Ming Liu, Hong Gao, Chunguang Xie, Gang Wang

Diabetes 2023;72(6):703–714

https://doi.org/10.2337/db22-0860

Published: 13 March 2023

View article titled, Glucose-Activated Switch Regulating Insulin Analog Secretion Enables Long-term Precise Glucose Control in Mice With Type 1 Diabetes

Meeting Abstracts

317-OR: The Novel Glucokinase GCK (Q26L) Gene Mutation Site Causes Diabetes

SHUHUI JI, HUA SHU, WENLI FENG, JINYANG ZHEN, JINGTING QIAO, YADI HUANG, SHANSHAN CHEN, MING LIU

Diabetes 2022;71(Supplement_1):317-OR

https://doi.org/10.2337/db22-317-OR

Published: 01 June 2022

View article titled, 317-OR: The Novel Glucokinase GCK (Q26L) Gene Mutation Site Causes Diabetes

Meeting Abstracts

1461-P: Quantifying Proinsulin Misfolding in the Endoplasmic Reticulum

ANOOP ARUNAGIRI, MD MAROOF ALAM, LEENA HAATAJA, PRAVEEN J. SAMY, SCOTT SOLEIMANPOUR, LESLIE S. SATIN, PAMELA ITKIN-ANSARI, MING LIU, PETER ARVAN

Diabetes 2022;71(Supplement_1):1461-P

https://doi.org/10.2337/db22-1461-P

Published: 01 June 2022

View article titled, 1461-P: Quantifying Proinsulin Misfolding in the Endoplasmic Reticulum

Meeting Abstracts

200-OR: IER3IP1 Is Critical for Maintaining Glucose Homeostasis through Regulating the Endoplasmic Reticulum Function and Survival of ß-Cells

JING YANG, JINYANG ZHEN, WENLI FENG, ZHENQIAN FAN, YUMENG HUANG, HUA SHU, XIN LI, JINGTING QIAO, YUXIN FAN, JINHONG SUN, NA LI, TENGLI LIU, SHUSEN WANG, XIAONA ZHANG, PETER ARVAN, MING LIU

Diabetes 2022;71(Supplement_1):200-OR

https://doi.org/10.2337/db22-200-OR

Published: 01 June 2022

View article titled, 200-OR: IER3IP1 Is Critical for Maintaining Glucose Homeostasis through Regulating the Endoplasmic Reticulum Function and Survival of ß-Cells

Meeting Abstracts

850-P: Greater HbA1c Reduction with iGlarLixi vs. Insulin Glargine and Lixisenatide Regardless of Levels at Screening: Subgroup Analysis of the LixiLan-O Asia Pacific Trial

YIFAN HE, WENYING YANG, DONG XIAOLIN, GUOYUE YUAN, MING LIU, JIANZHONG XIAO, SHENGHONG GU, LIJUAN CHEN, ELISABETH SOUHAMI

Diabetes 2022;71(Supplement_1):850-P

https://doi.org/10.2337/db22-850-P

Published: 01 June 2022

View article titled, 850-P: Greater HbA1c Reduction with iGlarLixi vs. Insulin Glargine and Lixisenatide Regardless of Levels at Screening: Subgroup Analysis of the LixiLan-O Asia Pacific Trial

Journal Articles

Endogenous Lipid-GPR120 Signaling Modulates Pancreatic Islet Homeostasis to Different Extents

Ya-Qin Du, Xue-Ying Sha, Jie Cheng, Jin Wang, Jing-Yu Lin, Wen-Tao An, Wei Pan, Li-Jun Zhang, Xiao-Na Tao, Yun-Fei Xu, Ying-Li Jia, Zhao Yang, Peng Xiao, Ming Liu, Jin-Peng Sun, Xiao Yu

Diabetes 2022;71(7):1454–1471

https://doi.org/10.2337/db21-0794

Published: 26 April 2022

View article titled, Endogenous Lipid-GPR120 Signaling Modulates Pancreatic Islet Homeostasis to Different Extents

Journal Articles

The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum

Xiaoxi Xu, Yumeng Huang, Xin Li, Peter Arvan, Ming Liu

Diabetes 2022;71(3):440–452

https://doi.org/10.2337/db21-0638

Published: 02 December 2021

View article titled, The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum

Meeting Abstracts

961-P: Efficacy and Safety of Once-Weekly Semaglutide vs. Once-Daily Sitagliptin as Add-On to Metformin in Subjects with Type 2 Diabetes (SUSTAIN China MRCT): A 30-Week Double-Blind, Phase 3a, Randomised Trial

LINONG JI, DONG XIAOLIN, FREDDY ELIASCHEWITZ, YIMING LI, YUFENG LI, SOO LIM, MING LIU, NING ZU, SOEREN RASMUSSEN, TRINE V. SKJOETH, GUOYUE YUAN, YU-YAO HUANG

Diabetes 2020;69(Supplement_1):961-P

https://doi.org/10.2337/db20-961-P

Published: 01 June 2020

View article titled, 961-P: Efficacy and Safety of Once-Weekly Semaglutide vs. Once-Daily Sitagliptin as Add-On to Metformin in Subjects with Type 2 Diabetes (SUSTAIN China MRCT): A 30-Week Double-Blind, Phase 3a, Randomised Trial

Journal Articles

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

Duc T. Tran, Anita Pottekat, Saiful A. Mir, Salvatore Loguercio, Insook Jang, Alexandre Rosa Campos, Kathleen M. Scully, Reyhaneh Lahmy, Ming Liu, Peter Arvan, William E. Balch, Randal J. Kaufman, Pamela Itkin-Ansari

Diabetes 2020;69(8):1723–1734

https://doi.org/10.2337/db20-0245

Published: 26 May 2020

View article titled, Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

Journal Articles

Role of Proinsulin Self-Association in Mutant INS Gene–Induced Diabetes of Youth

Jinhong Sun, Yi Xiong, Xin Li, Leena Haataja, Wei Chen, Saiful A. Mir, Li Lv, Rachel Madley, Dennis Larkin, Arfah Anjum, Balamurugan Dhayalan, Nischay Rege, Nalinda P. Wickramasinghe, Michael A. Weiss, Pamela Itkin-Ansari, Randal J. Kaufman, David A. Ostrov, Peter Arvan, Ming Liu

Diabetes 2020;69(5):954–964

https://doi.org/10.2337/db19-1106

Published: 05 March 2020

View article titled, Role of Proinsulin Self-Association in Mutant <em>INS</em> Gene–Induced Diabetes of Youth

Includes: Supplementary data

Meeting Abstracts

1096-P: Determining the Optimal Fasting Glucose Target for Patients with Type 2 Diabetes: Results of the FPG Goal Trial

WENYING YANG, JIANHUA MA, GUOYUE YUAN, LING LI, MIN ZHANG, YIBING LU, XINHUA YE, WEIHONG SONG, MING LIU, JUN WU, RIQIU CHEN, NAN CUI, YUNGUANG LI, XIA ZHANG, JIN-KUI YANG

Diabetes 2019;68(Supplement_1):1096-P

https://doi.org/10.2337/db19-1096-P

Published: 01 June 2019

View article titled, 1096-P: Determining the Optimal Fasting Glucose Target for Patients with Type 2 Diabetes: Results of the FPG Goal Trial

NARROW

Pancreatic β cell TRAPδ deficiency reduces insulin production but improves insulin sensitivity

1745-P: IPO13 Maintains Glucose Homeostasis by Regulating Insulin Secretion and α-Cell Expansion

1869-LB: Efficacy and Safety of iGlarLixi vs. IDegAsp in Chinese People with Type 2 Diabetes (T2D) Suboptimally Controlled with Oral Antidiabetic Drug(s) (OAD)—The SoliD Randomized Controlled Trial

1743-P: STING Mediates Glucose-Induced Insulin Secretion through Pax6

Foxj3 Regulates Thermogenesis of Brown and Beige Fat Via Induction of PGC-1α

236-OR: Pancreatic ß-Cell TRAPδ Deficiency Reduces Insulin Production but Improves Insulin Sensitivity

503-P: Distinct Effects of a Novel GCK-MODY Mutation on Lipid Profiles and Diabetic Complications

1752-P: The Role of Translocon-Associated Protein Subunit γ in Insulin Biosynthesis and Glucose Homeostasis

778-P: Efficacy and Safety of Supaglutide as Add-on to Metformin in Patients with Type 2 Diabetes

Glucose-Activated Switch Regulating Insulin Analog Secretion Enables Long-term Precise Glucose Control in Mice With Type 1 Diabetes

317-OR: The Novel Glucokinase GCK (Q26L) Gene Mutation Site Causes Diabetes

1461-P: Quantifying Proinsulin Misfolding in the Endoplasmic Reticulum

200-OR: IER3IP1 Is Critical for Maintaining Glucose Homeostasis through Regulating the Endoplasmic Reticulum Function and Survival of ß-Cells

850-P: Greater HbA1c Reduction with iGlarLixi vs. Insulin Glargine and Lixisenatide Regardless of Levels at Screening: Subgroup Analysis of the LixiLan-O Asia Pacific Trial

Endogenous Lipid-GPR120 Signaling Modulates Pancreatic Islet Homeostasis to Different Extents

The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum

961-P: Efficacy and Safety of Once-Weekly Semaglutide vs. Once-Daily Sitagliptin as Add-On to Metformin in Subjects with Type 2 Diabetes (SUSTAIN China MRCT): A 30-Week Double-Blind, Phase 3a, Randomised Trial

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

Role of Proinsulin Self-Association in Mutant INS Gene–Induced Diabetes of Youth

1096-P: Determining the Optimal Fasting Glucose Target for Patients with Type 2 Diabetes: Results of the FPG Goal Trial

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