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Journal Articles

An Essential Role of IER3IP1 in β-Cell Development and Proinsulin Trafficking

Free
Wenli Feng, Peter Arvan, Ming Liu
Journal: Diabetes
Diabetes 2025;74(4):455–457
https://doi.org/10.2337/dbi24-0045
Published: 20 March 2025
View articletitled, An Essential Role of IER3IP1 in β-Cell Development and Proinsulin Trafficking
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Journal Articles

Role of Sec61α2 Translocon in Insulin Biosynthesis

Available to Purchase
Xiaoxi Xu, Thomas W. Bell, Truc Le, Ivy Zhao, Emily Walker, Yiqing Wang, Ning Xu, Scott A. Soleimanpour, Holger A. Russ, Ling Qi, Billy Tsai, Ming Liu, Peter Arvan
Journal: Diabetes
Diabetes 2024;73(12):2034–2044
https://doi.org/10.2337/db24-0115
Published: 26 September 2024
View articletitled, Role of Sec61α2 Translocon in Insulin Biosynthesis
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Journal Articles

Pancreatic β-Cell TRAPδ Deficiency Reduces Insulin Production but Improves Insulin Sensitivity

Available to Purchase
Jiyun Guo, Yanshu Yang, Ning Xu, Xin Li, Ying Yang, Wenli Feng, Yuanyuan Ye, Xiaoxi Xu, Jingqiu Cui, Ming Liu, Yumeng Huang
Journal: Diabetes
Diabetes 2024;73(11):1848–1861
https://doi.org/10.2337/db23-0984
Published: 21 August 2024
View articletitled, Pancreatic β-Cell TRAPδ Deficiency Reduces Insulin Production but Improves Insulin Sensitivity
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Meeting Abstracts

1869-LB: Efficacy and Safety of iGlarLixi vs. IDegAsp in Chinese People with Type 2 Diabetes (T2D) Suboptimally Controlled with Oral Antidiabetic Drug(s) (OAD)—The SoliD Randomized Controlled Trial

Free
MING LIU, WEIJUN GU, LI CHEN, YANBING LI, HONGYU KUANG, JIANLING DU, AGUSTINA ALVAREZ, FELIPE LAUAND, SR., ELISABETH SOUHAMI, JIEWEN ZHANG, WEIYA XU, QIN DU, YIMING MU
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1869-LB
https://doi.org/10.2337/db24-1869-LB
Published: 14 June 2024
View articletitled, 1869-LB: Efficacy and Safety of iGlarLixi vs. IDegAsp in Chinese People with Type 2 Diabetes (T2D) Suboptimally Controlled with Oral Antidiabetic Drug(s) (OAD)—The SoliD Randomized Controlled Trial
Meeting Abstracts

1743-P: STING Mediates Glucose-Induced Insulin Secretion through Pax6

Free
ZIYUE ZHANG, JINGTING QIAO, YANG LIU, MING LIU
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1743-P
https://doi.org/10.2337/db24-1743-P
Published: 14 June 2024
View articletitled, 1743-P: STING Mediates Glucose-Induced Insulin Secretion through Pax6
Meeting Abstracts

1745-P: IPO13 Maintains Glucose Homeostasis by Regulating Insulin Secretion and α-Cell Expansion

Free
QINYING ZHAO, YING YANG, SHUHUI JI, YUANSI CHEN, WENLI FENG, MING LIU
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1745-P
https://doi.org/10.2337/db24-1745-P
Published: 14 June 2024
View articletitled, 1745-P: IPO13 Maintains Glucose Homeostasis by Regulating Insulin Secretion and α-Cell Expansion
Journal Articles

Foxj3 Regulates Thermogenesis of Brown and Beige Fat Via Induction of PGC-1α

Free
Jincan Huang, Yujie Zhang, Xuenan Zhou, Jiani Song, Yueyao Feng, Tongtong Qiu, Sufang Sheng, Menglin Zhang, Xi Zhang, Jingran Hao, Lei Zhang, Yinliang Zhang, Xiaorong Li, Ming Liu, Yongsheng Chang
Journal: Diabetes
Diabetes 2024;73(2):178–196
https://doi.org/10.2337/db23-0454
Published: 08 November 2023
View articletitled, Foxj3 Regulates Thermogenesis of Brown and Beige Fat Via Induction of PGC-1α
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Meeting Abstracts

1752-P: The Role of Translocon-Associated Protein Subunit γ in Insulin Biosynthesis and Glucose Homeostasis

Free
NING XU, XIAOXI XU, JINGXIN HU, JIYUN GUO, JINGQIU CUI, MING LIU, WENLI FENG, XIN LI
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1752-P
https://doi.org/10.2337/db23-1752-P
Published: 20 June 2023
View articletitled, 1752-P: The Role of Translocon-Associated Protein Subunit γ in Insulin Biosynthesis and Glucose Homeostasis
Meeting Abstracts

778-P: Efficacy and Safety of Supaglutide as Add-on to Metformin in Patients with Type 2 Diabetes

Free
DILBAR ANWAR, YUQIAN BAO, YUE ZHOU, SI CHEN, JIAN ZHOU, LIANG LI, ZHIFENG CHENG, XIAOLIN DONG, XIAOXIA SHI, XIUHAI SU, LIPING LI, HAIFANG WANG, YIHUA WANG, SHU LI, QINGJU LI, XING LI, MING LIU, JIAO SUN, NAIQING ZHAO, YEHONG YANG, JIANHUA MA, YIMING LI, QINGHUA WANG, WEIPING JIA
Journal: Diabetes
Diabetes 2023;72(Supplement_1):778-P
https://doi.org/10.2337/db23-778-P
Published: 20 June 2023
View articletitled, 778-P: Efficacy and Safety of Supaglutide as Add-on to Metformin in Patients with Type 2 Diabetes
Meeting Abstracts

236-OR: Pancreatic ß-Cell TRAPδ Deficiency Reduces Insulin Production but Improves Insulin Sensitivity

Free
JIYUN GUO, YANSHU YANG, NING XU, YING YANG, WENLI FENG, YUANYUAN YE, XIN LI, XIAOXI XU, JINGQIU CUI, YUMENG HUANG, MING LIU
Journal: Diabetes
Diabetes 2023;72(Supplement_1):236-OR
https://doi.org/10.2337/db23-236-OR
Published: 20 June 2023
View articletitled, 236-OR: Pancreatic ß-Cell TRAPδ Deficiency Reduces Insulin Production but Improves Insulin Sensitivity
Meeting Abstracts

503-P: Distinct Effects of a Novel GCK-MODY Mutation on Lipid Profiles and Diabetic Complications

Free
YADI HUANG, YUXIN FAN, XIN LI, SHUHUI JI, SHANSHAN CHEN, JINGQIU CUI, WENLI FENG, HUA SHU, MING LIU
Journal: Diabetes
Diabetes 2023;72(Supplement_1):503-P
https://doi.org/10.2337/db23-503-P
Published: 20 June 2023
View articletitled, 503-P: Distinct Effects of a Novel GCK-MODY Mutation on Lipid Profiles and Diabetic Complications
Journal Articles

Glucose-Activated Switch Regulating Insulin Analog Secretion Enables Long-term Precise Glucose Control in Mice With Type 1 Diabetes

Free
Lifang Xie, Wanling Lu, Yanhan Zhang, Lu Deng, Ming Liu, Hong Gao, Chunguang Xie, Gang Wang
Journal: Diabetes
Diabetes 2023;72(6):703–714
https://doi.org/10.2337/db22-0860
Published: 13 March 2023
View articletitled, Glucose-Activated Switch Regulating Insulin Analog Secretion Enables Long-term Precise Glucose Control in Mice With Type 1 Diabetes
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Meeting Abstracts

317-OR: The Novel Glucokinase GCK (Q26L) Gene Mutation Site Causes Diabetes

Free
SHUHUI JI, HUA SHU, WENLI FENG, JINYANG ZHEN, JINGTING QIAO, YADI HUANG, SHANSHAN CHEN, MING LIU
Journal: Diabetes
Diabetes 2022;71(Supplement_1):317-OR
https://doi.org/10.2337/db22-317-OR
Published: 01 June 2022
View articletitled, 317-OR: The Novel Glucokinase GCK (Q26L) Gene Mutation Site Causes Diabetes
Meeting Abstracts

1461-P: Quantifying Proinsulin Misfolding in the Endoplasmic Reticulum

Free
ANOOP ARUNAGIRI, MD MAROOF ALAM, LEENA HAATAJA, PRAVEEN J. SAMY, SCOTT SOLEIMANPOUR, LESLIE S. SATIN, PAMELA ITKIN-ANSARI, MING LIU, PETER ARVAN
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1461-P
https://doi.org/10.2337/db22-1461-P
Published: 01 June 2022
View articletitled, 1461-P: Quantifying Proinsulin Misfolding in the Endoplasmic Reticulum
Meeting Abstracts

200-OR: IER3IP1 Is Critical for Maintaining Glucose Homeostasis through Regulating the Endoplasmic Reticulum Function and Survival of ß-Cells

Free
JING YANG, JINYANG ZHEN, WENLI FENG, ZHENQIAN FAN, YUMENG HUANG, HUA SHU, XIN LI, JINGTING QIAO, YUXIN FAN, JINHONG SUN, NA LI, TENGLI LIU, SHUSEN WANG, XIAONA ZHANG, PETER ARVAN, MING LIU
Journal: Diabetes
Diabetes 2022;71(Supplement_1):200-OR
https://doi.org/10.2337/db22-200-OR
Published: 01 June 2022
View articletitled, 200-OR: IER3IP1 Is Critical for Maintaining Glucose Homeostasis through Regulating the Endoplasmic Reticulum Function and Survival of ß-Cells
Meeting Abstracts

850-P: Greater HbA1c Reduction with iGlarLixi vs. Insulin Glargine and Lixisenatide Regardless of Levels at Screening: Subgroup Analysis of the LixiLan-O Asia Pacific Trial

Free
YIFAN HE, WENYING YANG, DONG XIAOLIN, GUOYUE YUAN, MING LIU, JIANZHONG XIAO, SHENGHONG GU, LIJUAN CHEN, ELISABETH SOUHAMI
Journal: Diabetes
Diabetes 2022;71(Supplement_1):850-P
https://doi.org/10.2337/db22-850-P
Published: 01 June 2022
View articletitled, 850-P: Greater HbA1c Reduction with iGlarLixi vs. Insulin Glargine and Lixisenatide Regardless of Levels at Screening: Subgroup Analysis of the LixiLan-O Asia Pacific Trial
Journal Articles

Endogenous Lipid-GPR120 Signaling Modulates Pancreatic Islet Homeostasis to Different Extents

Free
Ya-Qin Du, Xue-Ying Sha, Jie Cheng, Jin Wang, Jing-Yu Lin, Wen-Tao An, Wei Pan, Li-Jun Zhang, Xiao-Na Tao, Yun-Fei Xu, Ying-Li Jia, Zhao Yang, Peng Xiao, Ming Liu, Jin-Peng Sun, Xiao Yu
Journal: Diabetes
Diabetes 2022;71(7):1454–1471
https://doi.org/10.2337/db21-0794
Published: 26 April 2022
View articletitled, Endogenous Lipid-GPR120 Signaling Modulates Pancreatic Islet Homeostasis to Different Extents
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Journal Articles

The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum

Free
Xiaoxi Xu, Yumeng Huang, Xin Li, Peter Arvan, Ming Liu
Journal: Diabetes
Diabetes 2022;71(3):440–452
https://doi.org/10.2337/db21-0638
Published: 02 December 2021
View articletitled, The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum
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Meeting Abstracts

961-P: Efficacy and Safety of Once-Weekly Semaglutide vs. Once-Daily Sitagliptin as Add-On to Metformin in Subjects with Type 2 Diabetes (SUSTAIN China MRCT): A 30-Week Double-Blind, Phase 3a, Randomised Trial

Free
LINONG JI, DONG XIAOLIN, FREDDY ELIASCHEWITZ, YIMING LI, YUFENG LI, SOO LIM, MING LIU, NING ZU, SOEREN RASMUSSEN, TRINE V. SKJOETH, GUOYUE YUAN, YU-YAO HUANG
Journal: Diabetes
Diabetes 2020;69(Supplement_1):961-P
https://doi.org/10.2337/db20-961-P
Published: 01 June 2020
View articletitled, 961-P: Efficacy and Safety of Once-Weekly Semaglutide vs. Once-Daily Sitagliptin as Add-On to Metformin in Subjects with Type 2 Diabetes (SUSTAIN China MRCT): A 30-Week Double-Blind, Phase 3a, Randomised Trial
Journal Articles

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

Free
Duc T. Tran, Anita Pottekat, Saiful A. Mir, Salvatore Loguercio, Insook Jang, Alexandre Rosa Campos, Kathleen M. Scully, Reyhaneh Lahmy, Ming Liu, Peter Arvan, William E. Balch, Randal J. Kaufman, Pamela Itkin-Ansari
Journal: Diabetes
Diabetes 2020;69(8):1723–1734
https://doi.org/10.2337/db20-0245
Published: 26 May 2020
View articletitled, Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding
Open the PDF for Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding in another window