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Mladen Vranic
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Journal Articles

Somatostatin Receptor Type 2 Antagonism Improves Glucagon Counterregulation in Biobreeding Diabetic Rats

Negar Karimian, Tairan Qin, Tao Liang, Mayowa Osundiji, Yachi Huang, Trevor Teich, Michael C. Riddell, Mark S. Cattral, David H. Coy, Mladen Vranic, Herbert Y. Gaisano
Journal: Diabetes
Diabetes 2013;62(8):2968–2977
https://doi.org/10.2337/db13-0164
Published: 17 July 2013
View article titled, Somatostatin Receptor Type 2 Antagonism Improves Glucagon Counterregulation in Biobreeding Diabetic Rats
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Journal Articles

Amelioration of Hypoglycemia Via Somatostatin Receptor Type 2 Antagonism in Recurrently Hypoglycemic Diabetic Rats

Jessica T.Y. Yue, Michael C. Riddell, Elena Burdett, David H. Coy, Suad Efendic, Mladen Vranic
Journal: Diabetes
Diabetes 2013;62(7):2215–2222
https://doi.org/10.2337/db12-1523
Published: 14 June 2013
View article titled, Amelioration of Hypoglycemia Via Somatostatin Receptor Type 2 Antagonism in Recurrently Hypoglycemic Diabetic Rats
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Journal Articles

Somatostatin Receptor Type 2 Antagonism Improves Glucagon and Corticosterone Counterregulatory Responses to Hypoglycemia in Streptozotocin-Induced Diabetic Rats

Jessica T.Y. Yue, Elena Burdett, David H. Coy, Adria Giacca, Suad Efendic, Mladen Vranic
Journal: Diabetes
Diabetes 2012;61(1):197–207
https://doi.org/10.2337/db11-0690
Published: 12 December 2011
View article titled, Somatostatin Receptor Type 2 Antagonism Improves Glucagon and Corticosterone Counterregulatory Responses to Hypoglycemia in Streptozotocin-Induced Diabetic Rats
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Includes: Supplementary data
Journal Articles

Ubiquitinated-Protein Aggregates Form in Pancreatic β-Cells During Diabetes-Induced Oxidative Stress and Are Regulated by Autophagy

Natalia A. Kaniuk, Michael Kiraly, Holly Bates, Mladen Vranic, Allen Volchuk, John H. Brumell
Journal: Diabetes
Diabetes 2007;56(4):930–939
https://doi.org/10.2337/db06-1160
Published: 01 April 2007
View article titled, Ubiquitinated-Protein Aggregates Form in Pancreatic β-Cells During Diabetes-Induced Oxidative Stress and Are Regulated by Autophagy
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Journal Articles

Combined Infusion of Epinephrine and Norepinephrine During Moderate Exercise Reproduces the Glucoregulatory Response of Intense Exercise

Stuart H. Kreisman, Jeffrey B. Halter, Mladen Vranic, Errol B. Marliss
Journal: Diabetes
Diabetes 2003;52(6):1347–1354
https://doi.org/10.2337/diabetes.52.6.1347
Published: 01 June 2003
View article titled, Combined Infusion of Epinephrine and Norepinephrine During Moderate Exercise Reproduces the Glucoregulatory Response of Intense Exercise
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Journal Articles

Diabetes Impairs Hypothalamo-Pituitary-Adrenal (HPA) Responses to Hypoglycemia, and Insulin Treatment Normalizes HPA but not Epinephrine Responses

Owen Chan, Stephen Chan, Karen Inouye, Kathy Shum, Stephen G. Matthews, Mladen Vranic
Journal: Diabetes
Diabetes 2002;51(6):1681–1689
https://doi.org/10.2337/diabetes.51.6.1681
Published: 01 June 2002
View article titled, Diabetes Impairs Hypothalamo-Pituitary-Adrenal (HPA) Responses to Hypoglycemia, and Insulin Treatment Normalizes HPA but not Epinephrine Responses
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Journal Articles

Intense Exercise Has Unique Effects on Both Insulin Release and Its Roles in Glucoregulation: Implications for Diabetes

Errol B. Marliss, Mladen Vranic
Journal: Diabetes
Diabetes 2002;51(suppl_1):S271–S283
https://doi.org/10.2337/diabetes.51.2007.S271
Published: 01 February 2002
View article titled, Intense Exercise Has Unique Effects on Both Insulin Release and Its Roles in Glucoregulation: <subtitle>Implications for Diabetes </subtitle>
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Journal Articles

The Effect of Systemic Versus Portal Insulin Delivery in Pancreas Transplantation on Insulin Action and VLDL Metabolism

André Carpentier, Bruce W. Patterson, Kristine D. Uffelman, Adria Giacca, Mladen Vranic, Mark S. Cattral, Gary F. Lewis
Journal: Diabetes
Diabetes 2001;50(6):1402–1413
https://doi.org/10.2337/diabetes.50.6.1402
Published: 01 June 2001
View article titled, The Effect of Systemic Versus Portal Insulin Delivery in Pancreas Transplantation on Insulin Action and VLDL Metabolism
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Journal Articles

Insulin-Independent Acute Restoration of Euglycemia Normalizes the Impaired Glucose Clearance During Exercise in Diabetic Dogs

Simon J Fisher, Michael Lekas, Z Qing Shi, Debra Bilinski, George Carvalho, Adria Giacca, Mladen Vranic
Journal: Diabetes
Diabetes 1997;46(11):1805–1812
https://doi.org/10.2337/diab.46.11.1805
Published: 01 November 1997
View article titled, Insulin-Independent Acute Restoration of Euglycemia Normalizes the Impaired Glucose Clearance During Exercise in Diabetic Dogs
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Journal Articles

Fatty Acids Mediate the Acute Extrahepatic Effects of Insulin on Hepatic Glucose Production in Humans

Gary F Lewis, Mladen Vranic, Patricia Harley, Adria Giacca
Journal: Diabetes
Diabetes 1997;46(7):1111–1119
https://doi.org/10.2337/diab.46.7.1111
Published: 01 July 1997
View article titled, Fatty Acids Mediate the Acute Extrahepatic Effects of Insulin on Hepatic Glucose Production in Humans
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Journal Articles

The Effect of Pioglitazone on Hepatic Glucose Uptake Measured With Indirect and Direct Methods in Alloxan-Induced Diabetic Dogs

Munehide Matsuhisa, Z Qing Shi, Calvin Wan, Michael Lekas, Carol D Rodgers, Adria Giacca, Ryuzo Kawamori, Mladen Vranic
Journal: Diabetes
Diabetes 1997;46(2):224–231
https://doi.org/10.2337/diab.46.2.224
Published: 01 February 1997
View article titled, The Effect of Pioglitazone on Hepatic Glucose Uptake Measured With Indirect and Direct Methods in Alloxan-Induced Diabetic Dogs
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Journal Articles

Hepatic Glucose Production Is Regulated Both by Direct Hepatic and Extrahepatic Effects of Insulin in Humans

Gary F Lewis, Bernard Zinman, Yolanda Groenewoud, Mladen Vranic, Adria Giacca
Journal: Diabetes
Diabetes 1996;45(4):454–462
https://doi.org/10.2337/diab.45.4.454
Published: 01 April 1996
View article titled, Hepatic Glucose Production Is Regulated Both by Direct Hepatic and Extrahepatic Effects of Insulin in Humans
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Journal Articles

The Roles of Catecholamines in Glucoregulation in Intense Exercise as Defined by the Islet Cell Clamp Technique

Ronald J Sigal, Simon Fisher, Jeffrey B Halter, Mladen Vranic, Errol B Marliss
Journal: Diabetes
Diabetes 1996;45(2):148–156
https://doi.org/10.2337/diab.45.2.148
Published: 01 February 1996
View article titled, The Roles of Catecholamines in Glucoregulation in Intense Exercise as Defined by the Islet Cell Clamp Technique
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Journal Articles

Importance of Substrate Changes in the Decrease of Hepatic Glucose Cycling During Insulin Infusion and Declining Glycemia in the Depancreatized Dog

Z Shi Qing, Adria Giacca, Simon Fisher, Hubert Vidal, Gerald Van De Werve, Mladen Vranic
Journal: Diabetes
Diabetes 1994;43(11):1284–1290
https://doi.org/10.2337/diab.43.11.1284
Published: 01 November 1994
View article titled, Importance of Substrate Changes in the Decrease of Hepatic Glucose Cycling During Insulin Infusion and Declining Glycemia in the Depancreatized Dog
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Journal Articles

Opposite Effects of Hyperglycemia and Insulin Deficiency on Liver Glycogen Synthase Phosphatase Activity in the Diabetic Rat

Louis Lavoie, Dimitrios Dimitrakoudis, Andre Marette, Borhane Annabi, Amira Klip, Mladen Vranic, Gerald Van De Werve
Journal: Diabetes
Diabetes 1993;42(2):363–366
https://doi.org/10.2337/diab.42.2.363
Published: 01 February 1993
View article titled, Opposite Effects of Hyperglycemia and Insulin Deficiency on Liver Glycogen Synthase Phosphatase Activity in the Diabetic Rat
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Journal Articles

Insulin Induces the Translocation of GLUT4 From a Unique Intracellular Organelle to Transverse Tubules in Rat Skeletal Muscle

André Marette, Elena Burdett, André Douen, Mladen Vranic, Amira Klip
Journal: Diabetes
Diabetes 1992;41(12):1562–1569
https://doi.org/10.2337/diab.41.12.1562
Published: 01 December 1992
View article titled, Insulin Induces the Translocation of GLUT4 From a Unique Intracellular Organelle to Transverse Tubules in Rat Skeletal Muscle
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Journal Articles

Banting Lecture: Glucose Turnover: A Key to Understanding the Pathogenesis of Diabetes (Indirect Effects of Insulin)

Mladen Vranic
Journal: Diabetes
Diabetes 1992;41(9):1188–1206
https://doi.org/10.2337/diab.41.9.1188
Published: 01 September 1992
View article titled, Banting Lecture: Glucose Turnover: A Key to Understanding the Pathogenesis of Diabetes (Indirect Effects of Insulin)
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Journal Articles

Differential Effects of IGF-I and Insulin on Glucoregulation and Fat Metabolism in Depancreatized Dogs

Adria Giacca, Rajiv Gupta, Suad Efendic, Kerstin Hall, Anna Skottner, Lavina Lickley, Mladen Vranic
Journal: Diabetes
Diabetes 1990;39(3):340–347
https://doi.org/10.2337/diab.39.3.340
Published: 01 March 1990
View article titled, Differential Effects of IGF-I and Insulin on Glucoregulation and Fat Metabolism in Depancreatized Dogs
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Journal Articles

Modeling Error and Apparent Isotope Discrimination Confound Estimation of Endogenous Glucose Production During Euglycemic Glucose Clamps

Diane T Finegood, Richard N Bergman, Mladen Vranic
Journal: Diabetes
Diabetes 1988;37(8):1025–1034
https://doi.org/10.2337/diab.37.8.1025
Published: 01 August 1988
View article titled, Modeling Error and Apparent Isotope Discrimination Confound Estimation of Endogenous Glucose Production During Euglycemic Glucose Clamps
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Journal Articles

Estimation of Endogenous Glucose Production During Hyperinsulinemic-Euglycemic Glucose Clamps: Comparison of Unlabeled and Labeled Exogenous Glucose Infusates

Diane T Finegood, Richard N Bergman, Mladen Vranic
Journal: Diabetes
Diabetes 1987;36(8):914–924
https://doi.org/10.2337/diab.36.8.914
Published: 01 August 1987
View article titled, Estimation of Endogenous Glucose Production During Hyperinsulinemic-Euglycemic Glucose Clamps: Comparison of Unlabeled and Labeled Exogenous Glucose Infusates
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