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Meeting Abstracts

199-OR: Beta-Cell IRS1 Deficiency Predisposes Female Mice to Developing Gestational Diabetes

XINGCHUN WANG, TAOFEEK USMAN, GOMA CHHETRI, WEN QUAN ZHENG, HSUAN YEH, MORRIS F. WHITE, H. HENRY DONG

Diabetes 2024;73(Supplement_1):199-OR

https://doi.org/10.2337/db24-199-OR

Published: 14 June 2024

View article titled, 199-OR: Beta-Cell IRS1 Deficiency Predisposes Female Mice to Developing Gestational Diabetes

Meeting Abstracts

1632-P: Effects of MTOR Signaling in Muscle-Specific Irs1/2 Knockout Mice

OLIVER STOEHR, KYLE D. COPPS, RONGYA TAO, MORRIS F. WHITE

Diabetes 2023;72(Supplement_1):1632-P

https://doi.org/10.2337/db23-1632-P

Published: 20 June 2023

View article titled, 1632-P: Effects of MTOR Signaling in Muscle-Specific Irs1/2 Knockout Mice

Journal Articles

Lower Hepatic Fat Is Associated With Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention

Diabetes 2023;72(3):362–366

https://doi.org/10.2337/db22-0441

Published: 16 December 2022

View article titled, Lower Hepatic Fat Is Associated With Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention

Journal Articles

Erratum. Inhibition of TNF-α Improves the Bladder Dysfunction That Is Associated With Type 2 Diabetes. Diabetes 2012;61: 2134–2145

Zongwei Wang, Zhiyong Cheng, Vivian Cristofaro, Jijun Li, Xingyuan Xiao, Pablo Gomez, Rongbin Ge, Edward Gong, Klemen Strle, Maryrose P. Sullivan, Rosalyn M. Adam, Morris F. White, Aria F. Olumi

Diabetes 2021;70(6):1416

https://doi.org/10.2337/db21-er06c

Published: 02 July 2021

View article titled, Erratum. Inhibition of TNF-α Improves the Bladder Dysfunction That Is Associated With Type 2 Diabetes. Diabetes 2012;61: 2134–2145

Meeting Abstracts

282-LB: Dysregulated FGF21 Links Hepatic Insulin Resistance to Dysfunctional BAT

OLIVER STOEHR, RONGYA TAO, KYLE D. COPPS, MORRIS F. WHITE

Diabetes 2019;68(Supplement_1):282-LB

https://doi.org/10.2337/db19-282-LB

Published: 01 June 2019

View article titled, 282-LB: Dysregulated FGF21 Links Hepatic Insulin Resistance to Dysfunctional BAT

Meeting Abstracts

1835-P: Deletion of Insulin Receptor Substrate 2 in AGRP Neurons Causes Beta-Cell Dysfunction

RONGYA TAO, KYLE D. COPPS, MORRIS F. WHITE, OLIVER STOEHR

Diabetes 2019;68(Supplement_1):1835-P

https://doi.org/10.2337/db19-1835-P

Published: 01 June 2019

View article titled, 1835-P: Deletion of Insulin Receptor Substrate 2 in AGRP Neurons Causes Beta-Cell Dysfunction

Meeting Abstracts

Foxo1-Ser253 Phosphorylation Regulates Glucose Homeostasis in Mice

HUI YAN, YUXIN WU, QUAN PAN, ZHENG SHEN, HONGTING ZHENG, MORRIS F. WHITE, YUXIANG SUN, SHAODONG GUO, SR.

Diabetes 2018;67(Supplement_1):1883-P

https://doi.org/10.2337/db18-1883-P

Published: 01 July 2018

View article titled, Foxo1-Ser253 Phosphorylation Regulates Glucose Homeostasis in Mice

Meeting Abstracts

Metabolic Dysfunction within Brown Adipose Tissue and Skeletal Muscle Caused by Complete Hepatic Insulin Resistance Is Reversible by FGF-21 Treatment

OLIVER STOEHR, RONGYA TAO, KYLE D. COPPS, MORRIS F. WHITE

Diabetes 2018;67(Supplement_1):1873-P

https://doi.org/10.2337/db18-1873-P

Published: 01 July 2018

View article titled, Metabolic Dysfunction within Brown Adipose Tissue and Skeletal Muscle Caused by Complete Hepatic Insulin Resistance Is Reversible by FGF-21 Treatment

Journal Articles

Myocardial Loss of IRS1 and IRS2 Causes Heart Failure and Is Controlled by p38α MAPK During Insulin Resistance

Yajuan Qi, Zihui Xu, Qinglei Zhu, Candice Thomas, Rajesh Kumar, Hao Feng, David E. Dostal, Morris F. White, Kenneth M. Baker, Shaodong Guo

Diabetes 2013;62(11):3887–3900

https://doi.org/10.2337/db13-0095

Published: 18 October 2013

View article titled, Myocardial Loss of IRS1 and IRS2 Causes Heart Failure and Is Controlled by p38α MAPK During Insulin Resistance

Includes: Supplementary data

Journal Articles

Direct Autocrine Action of Insulin on β-Cells: Does It Make Physiological Sense?

Christopher J. Rhodes, Morris F. White, John L. Leahy, Steven E. Kahn

Diabetes 2013;62(7):2157–2163

https://doi.org/10.2337/db13-0246

Published: 14 June 2013

View article titled, Direct Autocrine Action of Insulin on β-Cells: Does It Make Physiological Sense?

Journal Articles

Pulsatile Portal Vein Insulin Delivery Enhances Hepatic Insulin Action and Signaling

Aleksey V. Matveyenko, David Liuwantara, Tatyana Gurlo, David Kirakossian, Chiara Dalla Man, Claudio Cobelli, Morris F. White, Kyle D. Copps, Elena Volpi, Satoshi Fujita, Peter C. Butler

Diabetes 2012;61(9):2269–2279

https://doi.org/10.2337/db11-1462

Published: 17 August 2012

View article titled, Pulsatile Portal Vein Insulin Delivery Enhances Hepatic Insulin Action and Signaling

Includes: Supplementary data

Journal Articles

Inhibition of TNF-α Improves the Bladder Dysfunction That Is Associated With Type 2 Diabetes

Zongwei Wang, Zhiyong Cheng, Vivian Cristofaro, Jijun Li, Xingyuan Xiao, Pablo Gomez, Rongbin Ge, Edward Gong, Klemen Strle, Maryrose P. Sullivan, Rosalyn M. Adam, Morris F. White, Aria F. Olumi

Diabetes 2012;61(8):2134–2145

https://doi.org/10.2337/db11-1763

Published: 17 July 2012

View article titled, Inhibition of TNF-α Improves the Bladder Dysfunction That Is Associated With Type 2 Diabetes

Includes: Supplementary data

Journal Articles

Breathing Room: The (Un)Natural History of Adipose Microhypoxia and Insulin Resistance

Kyle D. Copps, Morris F. White

Diabetes 2009;58(1):26–27

https://doi.org/10.2337/db08-1517

Published: 01 January 2009

View article titled, Breathing Room: The (Un)Natural History of Adipose Microhypoxia and Insulin Resistance

Journal Articles

The Repression of IRS2 Gene by ATF3, a Stress-Inducible Gene, Contributes to Pancreatic β-Cell Apoptosis

Dan Li, Xin Yin, Erik J. Zmuda, Christopher C. Wolford, Xiaocheng Dong, Morris F. White, Tsonwin Hai

Diabetes 2008;57(3):635–644

https://doi.org/10.2337/db07-0717

Published: 01 March 2008

View article titled, The Repression of IRS2 Gene by ATF3, a Stress-Inducible Gene, Contributes to Pancreatic β-Cell Apoptosis

Includes: Supplementary data

Journal Articles

Islet-Sparing Effects of Protein Tyrosine Phosphatase-1b Deficiency Delays Onset of Diabetes in IRS2 Knockout Mice

Jake A. Kushner, Fawaz G. Haj, Lori D. Klaman, Matthew A. Dow, Barbara B. Kahn, Benjamin G. Neel, Morris F. White

Diabetes 2004;53(1):61–66

https://doi.org/10.2337/diabetes.53.1.61

Published: 01 January 2004

View article titled, Islet-Sparing Effects of Protein Tyrosine Phosphatase-1b Deficiency Delays Onset of Diabetes in IRS2 Knockout Mice

Journal Articles

Molecular Mechanisms of Insulin Resistance in IRS-2-Deficient Hepatocytes

Angela M. Valverde, Deborah J. Burks, Isabel Fabregat, Tracey L. Fisher, José Carretero, Morris F. White, Manuel Benito

Diabetes 2003;52(9):2239–2248

https://doi.org/10.2337/diabetes.52.9.2239

Published: 01 September 2003

View article titled, Molecular Mechanisms of Insulin Resistance in IRS-2-Deficient Hepatocytes

Journal Articles

Insulin Signaling After Exercise in Insulin Receptor Substrate-2-Deficient Mice

Kirsten F. Howlett, Kei Sakamoto, Michael F. Hirshman, William G. Aschenbach, Matthew Dow, Morris F. White, Laurie J. Goodyear

Diabetes 2002;51(2):479–483

https://doi.org/10.2337/diabetes.51.2.479

Published: 01 February 2002

View article titled, Insulin Signaling After Exercise in Insulin Receptor Substrate-2-Deficient Mice

Journal Articles

Role of Allelic Variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in Moderate-to-Severe Insulin Resistance of Women With Polycystic Ovary Syndrome

Samira Ait El Mkadem, Corinne Lautier, Françoise Macari, Nicolas Molinari, Patrick Lefèbvre, Eric Renard, Jean Christophe Gris, Gérard Cros, Jean Pierre Daurès, Jacques Bringer, Morris F. White, Florin Grigorescu

Diabetes 2001;50(9):2164–2168

https://doi.org/10.2337/diabetes.50.9.2164

Published: 01 September 2001

View article titled, Role of Allelic Variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in Moderate-to-Severe Insulin Resistance of Women With Polycystic Ovary Syndrome

Journal Articles

Human Skeletal Muscle Insulin Receptor Substrate-1: Characterization of the cDNA, Gene, and Chromosomal Localization

Eiichi Araki, Xiao-Jian Sun, Burritt L Haag, III, Lee-Ming Chuang, Yitao Zhang, Teresa L Yang-Feng, Morris F White, C Ronald Kahn

Diabetes 1993;42(7):1041–1054

https://doi.org/10.2337/diab.42.7.1041

Published: 01 July 1993

View article titled, Human Skeletal Muscle Insulin Receptor Substrate-1: Characterization of the cDNA, Gene, and Chromosomal Localization

Journal Articles

The New Elements of Insulin Signaling: Insulin Receptor Substrate-1 and Proteins With SH2 Domains

Martin G Myers, Jr, Morris F White

Diabetes 1993;42(5):643–650

https://doi.org/10.2337/diab.42.5.643

Published: 01 May 1993

View article titled, The New Elements of Insulin Signaling: Insulin Receptor Substrate-1 and Proteins With SH2 Domains

NARROW

199-OR: Beta-Cell IRS1 Deficiency Predisposes Female Mice to Developing Gestational Diabetes

1632-P: Effects of MTOR Signaling in Muscle-Specific Irs1/2 Knockout Mice

Lower Hepatic Fat Is Associated With Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention

Erratum. Inhibition of TNF-α Improves the Bladder Dysfunction That Is Associated With Type 2 Diabetes. Diabetes 2012;61: 2134–2145

282-LB: Dysregulated FGF21 Links Hepatic Insulin Resistance to Dysfunctional BAT

1835-P: Deletion of Insulin Receptor Substrate 2 in AGRP Neurons Causes Beta-Cell Dysfunction

Foxo1-Ser253 Phosphorylation Regulates Glucose Homeostasis in Mice

Metabolic Dysfunction within Brown Adipose Tissue and Skeletal Muscle Caused by Complete Hepatic Insulin Resistance Is Reversible by FGF-21 Treatment

Myocardial Loss of IRS1 and IRS2 Causes Heart Failure and Is Controlled by p38α MAPK During Insulin Resistance

Direct Autocrine Action of Insulin on β-Cells: Does It Make Physiological Sense?

Pulsatile Portal Vein Insulin Delivery Enhances Hepatic Insulin Action and Signaling

Inhibition of TNF-α Improves the Bladder Dysfunction That Is Associated With Type 2 Diabetes

Breathing Room: The (Un)Natural History of Adipose Microhypoxia and Insulin Resistance

The Repression of IRS2 Gene by ATF3, a Stress-Inducible Gene, Contributes to Pancreatic β-Cell Apoptosis

Islet-Sparing Effects of Protein Tyrosine Phosphatase-1b Deficiency Delays Onset of Diabetes in IRS2 Knockout Mice

Molecular Mechanisms of Insulin Resistance in IRS-2-Deficient Hepatocytes

Insulin Signaling After Exercise in Insulin Receptor Substrate-2-Deficient Mice

Role of Allelic Variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in Moderate-to-Severe Insulin Resistance of Women With Polycystic Ovary Syndrome

Human Skeletal Muscle Insulin Receptor Substrate-1: Characterization of the cDNA, Gene, and Chromosomal Localization

The New Elements of Insulin Signaling: Insulin Receptor Substrate-1 and Proteins With SH2 Domains

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