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Meeting Abstracts

10-PUB: Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Response to a Lifestyle or Senolytic Intervention in Older Adults with Obesity—A Double-Blind, Placebo-Controlled, Randomized Trial

GAVIN CONNOLLY, ARIANNE ASLAMY, JIA NIE, MORVARID KABIR, MONICA C. SERRA, SARA E. ESPINOZA, NICOLAS MUSI

Diabetes 2024;73(Supplement_1):10-PUB

https://doi.org/10.2337/db24-10-PUB

Published: 14 June 2024

View article titled, 10-PUB: Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Response to a Lifestyle or Senolytic Intervention in Older Adults with Obesity—A Double-Blind, Placebo-Controlled, Randomized Trial

Meeting Abstracts

1607-P: FGF1 Induces Glucokinase Upregulation and Increased Lactate Export in Mouse Hepatocytes

MORVARID KABIR, MARILYN ADER, NAREG THOMAS, EKIHIRO SEKI, RICHARD N. BERGMAN

Diabetes 2023;72(Supplement_1):1607-P

https://doi.org/10.2337/db23-1607-P

Published: 20 June 2023

View article titled, 1607-P: FGF1 Induces Glucokinase Upregulation and Increased Lactate Export in Mouse Hepatocytes

Meeting Abstracts

123-LB: Extended Fasting Reveals Effect of Canagliflozin to Mobilize Ketones in Canines

MARILYN ADER, RASHIN SEDIGHI, MORVARID KABIR, RICHARD N. BERGMAN

Diabetes 2022;71(Supplement_1):123-LB

https://doi.org/10.2337/db22-123-LB

Published: 01 June 2022

View article titled, 123-LB: Extended Fasting Reveals Effect of Canagliflozin to Mobilize Ketones in Canines

Meeting Abstracts

1342-P: Reduction of Glucokinase and Glucokinase Regulatory Protein Expression by siRNA Is Associated with the Reduction of Lactate and Pyruvate Export from Canine Hepatocytes

MORVARID KABIR, MARILYN ADER, RICHARD N. BERGMAN

Diabetes 2022;71(Supplement_1):1342-P

https://doi.org/10.2337/db22-1342-P

Published: 01 June 2022

View article titled, 1342-P: Reduction of Glucokinase and Glucokinase Regulatory Protein Expression by siRNA Is Associated with the Reduction of Lactate and Pyruvate Export from Canine Hepatocytes

Meeting Abstracts

1300-P: Novel Insulin Modified Oral Glucose Tolerance Test Improves the Estimation of Insulin Sensitivity and Glucose Effectiveness

DARKO STEFANOVSKI, FRANCESCA PICCININI, MARILYN ADER, MORVARID KABIR, RICHARD N. BERGMAN

Diabetes 2022;71(Supplement_1):1300-P

https://doi.org/10.2337/db22-1300-P

Published: 01 June 2022

View article titled, 1300-P: Novel Insulin Modified Oral Glucose Tolerance Test Improves the Estimation of Insulin Sensitivity and Glucose Effectiveness

Meeting Abstracts

120-OR: Dapagliflozin Increases Adiponectin and Its Receptors, and Reduces Inflammation and Ceramide Synthesis Enzymes in the Obese Prediabetic Dog

MORVARID KABIR, RICHARD N. BERGMAN, V. SASHI GOPAUL, HSIUCHIUNG YANG, CATHRYN M. KOLKA

Diabetes 2021;70(Supplement_1):120-OR

https://doi.org/10.2337/db21-120-OR

Published: 01 June 2021

View article titled, 120-OR: Dapagliflozin Increases Adiponectin and Its Receptors, and Reduces Inflammation and Ceramide Synthesis Enzymes in the Obese Prediabetic Dog

Meeting Abstracts

1711-P: Dapagliflozin Promotes Adipose Beiging and Lipolysis and Reduces Adipocyte Size in the Obese Prediabetic Dog

MORVARID KABIR, RICHARD N. BERGMAN, FRANCESCA PICCININI, DARKO STEFANOVSKI, V. SASHI GOPAUL, HSIU-CHIUNG YANG, CATHRYN M. KOLKA

Diabetes 2020;69(Supplement_1):1711-P

https://doi.org/10.2337/db20-1711-P

Published: 01 June 2020

View article titled, 1711-P: Dapagliflozin Promotes Adipose Beiging and Lipolysis and Reduces Adipocyte Size in the Obese Prediabetic Dog

Journal Articles

Erratum. Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes. Diabetes 2019;68: 1709–1716

Richard N. Bergman, Francesca Piccinini, Morvarid Kabir, Cathryn M. Kolka, Marilyn Ader

Diabetes 2019;68(12):2350

https://doi.org/10.2337/db19-er12a

Published: 09 October 2019

View article titled, Erratum. Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes. Diabetes 2019;68: 1709–1716

Journal Articles

Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes

Richard N. Bergman, Francesca Piccinini, Morvarid Kabir, Cathryn M. Kolka, Marilyn Ader

Diabetes 2019;68(9):1709–1716

https://doi.org/10.2337/db19-0098

Published: 14 August 2019

View article titled, Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes

Meeting Abstracts

1761-P: Brain-Restricted CB1-Receptor Antagonists Increase Oxygen Consumption Rate and Promote Beiging in 3T3-L1 Adipocytes Similar to Rimonabant Suggesting that Central Effects Can Be Avoided

REBECCA K. PASZKIEWICZ, RICHARD N. BERGMAN, AARON FRANK, ORISON O. WOOLCOTT, ROBERTA DE SOUZA SANTOS, MALINI S. IYER, DEBORAH CLEGG, MORVARID KABIR

Diabetes 2019;68(Supplement_1):1761-P

https://doi.org/10.2337/db19-1761-P

Published: 01 June 2019

View article titled, 1761-P: Brain-Restricted CB1-Receptor Antagonists Increase Oxygen Consumption Rate and Promote Beiging in 3T3-L1 Adipocytes Similar to Rimonabant Suggesting that Central Effects Can Be Avoided

Meeting Abstracts

Evidence of CB1-Receptor Antagonism in Fat-Fed Dogs Promoting Beiging of Adipose Tissue Mainly via Activation of Sarco/Endoplasmic Reticulum Ca2+ ATPase 2b and Ryanodine Receptor 2

REBECCA L. PASZKIEWICZ, RICHARD N. BERGMAN, JOYCE M. RICHEY, MALINI S. IYER, ORISON O. WOOLCOTT, CATHRYN M. KOLKA, DEBORAH CLEGG, MORVARID KABIR

Diabetes 2018;67(Supplement_1):2010-P

https://doi.org/10.2337/db18-2010-P

Published: 01 July 2018

View article titled, Evidence of CB1-Receptor Antagonism in Fat-Fed Dogs Promoting Beiging of Adipose Tissue Mainly via Activation of Sarco/Endoplasmic Reticulum Ca2+ ATPase 2b and Ryanodine Receptor 2

Journal Articles

Variability of Directly Measured First-Pass Hepatic Insulin Extraction and Its Association With Insulin Sensitivity and Plasma Insulin

Isaac Asare-Bediako, Rebecca L. Paszkiewicz, Stella P. Kim, Orison O. Woolcott, Cathryn M. Kolka, Miguel A. Burch, Morvarid Kabir, Richard N. Bergman

Diabetes 2018;67(8):1495–1503

https://doi.org/10.2337/db17-1520

Published: 11 May 2018

View article titled, Variability of Directly Measured First-Pass Hepatic Insulin Extraction and Its Association With Insulin Sensitivity and Plasma Insulin

Journal Articles

Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet

Malini S. Iyer, Richard N. Bergman, Jeremy E. Korman, Orison O. Woolcott, Morvarid Kabir, Ronald G. Victor, Deborah J. Clegg, Cathryn Kolka

Diabetes 2016;65(11):3453–3463

https://doi.org/10.2337/db16-0698

Published: 05 August 2016

View article titled, Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet

Includes: Supplementary data

Journal Articles

Failure of Homeostatic Model Assessment of Insulin Resistance to Detect Marked Diet-Induced Insulin Resistance in Dogs

Marilyn Ader, Darko Stefanovski, Joyce M. Richey, Stella P. Kim, Cathryn M. Kolka, Viorica Ionut, Morvarid Kabir, Richard N. Bergman

Diabetes 2014;63(6):1914–1919

https://doi.org/10.2337/db13-1215

Published: 15 May 2014

View article titled, Failure of Homeostatic Model Assessment of Insulin Resistance to Detect Marked Diet-Induced Insulin Resistance in Dogs

Journal Articles

Metabolic Dysregulation With Atypical Antipsychotics Occurs in the Absence of Underlying Disease A Placebo-Controlled Study of Olanzapine and Risperidone in Dogs

Marilyn Ader, Stella P. Kim, Karyn J. Catalano, Viorica Ionut, Katrin Hucking, Joyce M. Richey, Morvarid Kabir, Richard N. Bergman

Diabetes 2005;54(3):862–871

https://doi.org/10.2337/diabetes.54.3.862

Published: 01 March 2005

View article titled, Metabolic Dysregulation With Atypical Antipsychotics Occurs in the Absence of Underlying Disease A Placebo-Controlled Study of Olanzapine and Risperidone in Dogs

NARROW

10-PUB: Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Response to a Lifestyle or Senolytic Intervention in Older Adults with Obesity—A Double-Blind, Placebo-Controlled, Randomized Trial

1607-P: FGF1 Induces Glucokinase Upregulation and Increased Lactate Export in Mouse Hepatocytes

123-LB: Extended Fasting Reveals Effect of Canagliflozin to Mobilize Ketones in Canines

1342-P: Reduction of Glucokinase and Glucokinase Regulatory Protein Expression by siRNA Is Associated with the Reduction of Lactate and Pyruvate Export from Canine Hepatocytes

1300-P: Novel Insulin Modified Oral Glucose Tolerance Test Improves the Estimation of Insulin Sensitivity and Glucose Effectiveness

120-OR: Dapagliflozin Increases Adiponectin and Its Receptors, and Reduces Inflammation and Ceramide Synthesis Enzymes in the Obese Prediabetic Dog

1711-P: Dapagliflozin Promotes Adipose Beiging and Lipolysis and Reduces Adipocyte Size in the Obese Prediabetic Dog

Erratum. Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes. Diabetes 2019;68: 1709–1716

Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes

1761-P: Brain-Restricted CB1-Receptor Antagonists Increase Oxygen Consumption Rate and Promote Beiging in 3T3-L1 Adipocytes Similar to Rimonabant Suggesting that Central Effects Can Be Avoided

Evidence of CB1-Receptor Antagonism in Fat-Fed Dogs Promoting Beiging of Adipose Tissue Mainly via Activation of Sarco/Endoplasmic Reticulum Ca2+ ATPase 2b and Ryanodine Receptor 2

Variability of Directly Measured First-Pass Hepatic Insulin Extraction and Its Association With Insulin Sensitivity and Plasma Insulin

Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet

Failure of Homeostatic Model Assessment of Insulin Resistance to Detect Marked Diet-Induced Insulin Resistance in Dogs

Metabolic Dysregulation With Atypical Antipsychotics Occurs in the Absence of Underlying Disease A Placebo-Controlled Study of Olanzapine and Risperidone in Dogs

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