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Neil B Ruderman
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Journal Articles

Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673–686

Christopher J. Nolan, Neil B. Ruderman, Steven E. Kahn, Oluf Pedersen, Marc Prentki
Journal: Diabetes
Diabetes 2015;64(10):e38–e39
https://doi.org/10.2337/dbi15-0002
Published: 16 September 2015
View article titled, Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673–686
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Journal Articles

Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes

Christopher J. Nolan, Neil B. Ruderman, Steven E. Kahn, Oluf Pedersen, Marc Prentki
Journal: Diabetes
Diabetes 2015;64(3):673–686
https://doi.org/10.2337/db14-0694
Published: 17 February 2015
View article titled, Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes
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Journal Articles

Pioglitazone Acutely Reduces Energy Metabolism and Insulin Secretion in Rats

Julien Lamontagne, Élise Jalbert-Arsenault, Émilie Pepin, Marie-Line Peyot, Neil B. Ruderman, Christopher J. Nolan, Erik Joly, S.R. Murthy Madiraju, Vincent Poitout, Marc Prentki
Journal: Diabetes
Diabetes 2013;62(6):2122–2129
https://doi.org/10.2337/db12-0428
Published: 20 May 2013
View article titled, Pioglitazone Acutely Reduces Energy Metabolism and Insulin Secretion in Rats
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Includes: Supplementary data
Journal Articles

Downregulation of AMPK Accompanies Leucine- and Glucose-Induced Increases in Protein Synthesis and Insulin Resistance in Rat Skeletal Muscle

Asish K. Saha, X. Julia Xu, Ebony Lawson, Rosangela Deoliveira, Amanda E. Brandon, Edward W. Kraegen, Neil B. Ruderman
Journal: Diabetes
Diabetes 2010;59(10):2426–2434
https://doi.org/10.2337/db09-1870
Published: 03 August 2010
View article titled, Downregulation of AMPK Accompanies Leucine- and Glucose-Induced Increases in Protein Synthesis and Insulin Resistance in Rat Skeletal Muscle
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Includes: Supplementary data
Journal Articles

Activation of AMP-Activated Protein Kinase by Interleukin-6 in Rat Skeletal Muscle: Association With Changes in cAMP, Energy State, and Endogenous Fuel Mobilization

Meghan Kelly, Marie-Soleil Gauthier, Asish K. Saha, Neil B. Ruderman
Journal: Diabetes
Diabetes 2009;58(9):1953–1960
https://doi.org/10.2337/db08-1293
Published: 05 June 2009
View article titled, Activation of AMP-Activated Protein Kinase by Interleukin-6 in Rat Skeletal Muscle: <subtitle>Association With Changes in cAMP, Energy State, and Endogenous Fuel Mobilization</subtitle>
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Journal Articles

Interleukin-6 Regulation of AMP-Activated Protein Kinase: Potential Role in the Systemic Response to Exercise and Prevention of the Metabolic Syndrome

Neil B. Ruderman, Charlotte Keller, Ann-Marie Richard, Asish K. Saha, Zhijun Luo, Xiaoqin Xiang, Mercedes Giralt, Vladimir B. Ritov, Elizabeth V. Menshikova, David E. Kelley, Juan Hidalgo, Bente K. Pedersen, Meghan Kelly
Journal: Diabetes
Diabetes 2006;55(Supplement_2):S48–S54
https://doi.org/10.2337/db06-S007
Published: 01 December 2006
View article titled, Interleukin-6 Regulation of AMP-Activated Protein Kinase: <subtitle>Potential Role in the Systemic Response to Exercise and Prevention of the Metabolic Syndrome</subtitle>
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Journal Articles

Palmitate-Induced Apoptosis in Cultured Bovine Retinal Pericytes: Roles of NAD(P)H Oxidase, Oxidant Stress, and Ceramide

Jose M. Cacicedo, Sunun Benjachareowong, Eva Chou, Neil B. Ruderman, Yasuo Ido
Journal: Diabetes
Diabetes 2005;54(6):1838–1845
https://doi.org/10.2337/diabetes.54.6.1838
Published: 01 June 2005
View article titled, Palmitate-Induced Apoptosis in Cultured Bovine Retinal Pericytes: <subtitle>Roles of NAD(P)H Oxidase, Oxidant Stress, and Ceramide</subtitle>
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Journal Articles

Glucose Autoregulates Its Uptake in Skeletal Muscle: Involvement of AMP-Activated Protein Kinase

Samar I. Itani, Asish K. Saha, Theodore G. Kurowski, Heather R. Coffin, Keith Tornheim, Neil B. Ruderman
Journal: Diabetes
Diabetes 2003;52(7):1635–1640
https://doi.org/10.2337/diabetes.52.7.1635
Published: 01 July 2003
View article titled, Glucose Autoregulates Its Uptake in Skeletal Muscle: <subtitle>Involvement of AMP-Activated Protein Kinase</subtitle>
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Journal Articles

AICAR Administration Causes an Apparent Enhancement of Muscle and Liver Insulin Action in Insulin-Resistant High-Fat-Fed Rats

Miguel A. Iglesias, Ji-Ming Ye, Georgia Frangioudakis, Asish K. Saha, Eva Tomas, Neil B. Ruderman, Gregory J. Cooney, Edward W. Kraegen
Journal: Diabetes
Diabetes 2002;51(10):2886–2894
https://doi.org/10.2337/diabetes.51.10.2886
Published: 01 October 2002
View article titled, AICAR Administration Causes an Apparent Enhancement of Muscle and Liver Insulin Action in Insulin-Resistant High-Fat-Fed Rats
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Journal Articles

Lipid-Induced Insulin Resistance in Human Muscle Is Associated With Changes in Diacylglycerol, Protein Kinase C, and IκB-α

Samar I. Itani, Neil B. Ruderman, Frank Schmieder, Guenther Boden
Journal: Diabetes
Diabetes 2002;51(7):2005–2011
https://doi.org/10.2337/diabetes.51.7.2005
Published: 01 July 2002
View article titled, Lipid-Induced Insulin Resistance in Human Muscle Is Associated With Changes in Diacylglycerol, Protein Kinase C, and IκB-α
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Journal Articles

Diet-Induced Muscle Insulin Resistance in Rats Is Ameliorated by Acute Dietary Lipid Withdrawal or a Single Bout of Exercise: Parallel Relationship Between Insulin Stimulation of Glucose Uptake and Suppression of Long-Chain Fatty Acyl-CoA

Nicholas D Oakes, Kim S Bell, Stuart M Furler, Souad Camilleri, Asish K Saha, Neil B Ruderman, Donald J Chisholm, Edward W Kraegen
Journal: Diabetes
Diabetes 1997;46(12):2022–2028
https://doi.org/10.2337/diab.46.12.2022
Published: 01 December 1997
View article titled, Diet-Induced Muscle Insulin Resistance in Rats Is Ameliorated by Acute Dietary Lipid Withdrawal or a Single Bout of Exercise: Parallel Relationship Between Insulin Stimulation of Glucose Uptake and Suppression of Long-Chain Fatty Acyl-CoA
Open the PDF for Diet-Induced Muscle Insulin Resistance in Rats Is Ameliorated by Acute Dietary Lipid Withdrawal or a Single Bout of Exercise: Parallel Relationship Between Insulin Stimulation of Glucose Uptake and Suppression of Long-Chain Fatty Acyl-CoA in another window
Journal Articles

Enhanced Stimulation of Diacylglycerol and Lipid Synthesis by Insulin in Denervated Muscle: Altered Protein Kinase C Activity and Possible Link to Insulin Resistance

Stanley J Heydrick, Neil B Ruderman, Theodore G Kurowski, Heather B Adams, Kim S Chen
Journal: Diabetes
Diabetes 1991;40(12):1707–1711
https://doi.org/10.2337/diab.40.12.1707
Published: 01 December 1991
View article titled, Enhanced Stimulation of Diacylglycerol and Lipid Synthesis by Insulin in Denervated Muscle: Altered Protein Kinase C Activity and Possible Link to Insulin Resistance
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Journal Articles

Partial Characterization of an Insulin-dependent Serum Factor that Regulates Ornithine Decarboxylase in Skeletal Muscle

Cheryl Conover, S Jaime Rozovski, Neil B Ruderman
Journal: Diabetes
Diabetes 1982;31(6):500–505
https://doi.org/10.2337/diab.31.6.500
Published: 01 June 1982
View article titled, Partial Characterization of an Insulin-dependent Serum Factor that Regulates Ornithine Decarboxylase in Skeletal Muscle
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Journal Articles

Regulation of Ornithine Decarboxylase in Skeletal Muscle: Evidence for the Involvement of an Insulin-dependent Serum Factor

Cheryl A Conover, S Jaime Rozovski, Neil B Ruderman
Journal: Diabetes
Diabetes 1981;30(8):678–684
https://doi.org/10.2337/diab.30.8.678
Published: 01 August 1981
View article titled, Regulation of Ornithine Decarboxylase in Skeletal Muscle: Evidence for the Involvement of an Insulin-dependent Serum Factor
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Journal Articles

Substrate Utilization in Perfused Skeletal Muscle

Neil B Ruderman, Michael N Goodman, Cheryl A Conover, Michael Berger
Journal: Diabetes
Diabetes 1979;28(Supplement_1):13–17
https://doi.org/10.2337/diab.28.1.S13
Published: 01 January 1979
View article titled, Substrate Utilization in Perfused Skeletal Muscle
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Journal Articles

The Effect of Physical Training on Glucose Tolerance and Plasma Lipids in Maturity-onset Diabetes

Neil B Ruderman, Om P Ganda, Klaus Johansen
Journal: Diabetes
Diabetes 1979;28(Supplement_1):89–92
https://doi.org/10.2337/diab.28.1.S89
Published: 01 January 1979
View article titled, The Effect of Physical Training on Glucose Tolerance and Plasma Lipids in Maturity-onset Diabetes
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Journal Articles

Glucose and Amino Acid Metabolism in Perfused Skeletal Muscle: Effect of Dichloroacetate

Michael N Goodman, PhD, Neil B Ruderman, MD, PhD, Thomas T Aoki, MD
Journal: Diabetes
Diabetes 1978;27(11):1065–1074
https://doi.org/10.2337/diab.27.11.1065
Published: 01 November 1978
View article titled, Glucose and Amino Acid Metabolism in Perfused Skeletal Muscle: Effect of Dichloroacetate
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Journal Articles

Glucose Metabolism in Rat Skeletal Muscle at Rest: Effect of Starvation, Diabetes, Ketone Bodies and Free Fatty Acids

Michael N Goodman, PhD, Michael Berger, MD, Neil B Ruderman, MD, PhD
Journal: Diabetes
Diabetes 1974;23(11):881–888
https://doi.org/10.2337/diab.23.11.881
Published: 01 November 1974
View article titled, Glucose Metabolism in Rat Skeletal Muscle at Rest: Effect of Starvation, Diabetes, Ketone Bodies and Free Fatty Acids
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Journal Articles

Effect of Acute Insulin Deprivation on Rat Liver Glucokinase

Neil B Ruderman, M.D., Vilma Lauris, M.A.
Journal: Diabetes
Diabetes 1968;17(10):611–616
https://doi.org/10.2337/diab.17.10.611
Published: 01 October 1968
View article titled, Effect of Acute Insulin Deprivation on Rat Liver Glucokinase
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