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Nigel Turner
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Journal Articles

Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice

Martina Beretta, Yumin Dai, Ellen M. Olzomer, Calum S. Vancuylenburg, José A. Santiago-Rivera, Ashleigh M. Philp, Stefan R. Hargett, Keyong Li, Divya P. Shah, Sing-Young Chen, Stephanie J. Alexopoulos, Catherine Li, Thurl E. Harris, Brendan Lee, Michel Wathier, Jennifer M. Cermak, Simon P. Tucker, Nigel Turner, Douglas A. Bayliss, Andrew Philp, Frances L. Byrne, Webster L. Santos, Kyle L. Hoehn
Journal: Diabetes
Diabetes 2024;73(3):374–384
https://doi.org/10.2337/db23-0233
Published: 23 October 2023
View articletitled, Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice
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Journal Articles

Loss of Krüppel-Like Factor 3 (KLF3/BKLF) Leads to Upregulation of the Insulin-Sensitizing Factor Adipolin (FAM132A/CTRP12/C1qdc2)

Kim S. Bell-Anderson, Alister P. Funnell, Helen Williams, Hanapi Mat Jusoh, Tiffany Scully, Wooi F. Lim, Jon G. Burdach, Ka Sin Mak, Alexander J. Knights, Andrew J. Hoy, Hannah R. Nicholas, Amanda Sainsbury, Nigel Turner, Richard C. Pearson, Merlin Crossley
Journal: Diabetes
Diabetes 2013;62(8):2728–2737
https://doi.org/10.2337/db12-1745
Published: 17 July 2013
View articletitled, Loss of Krüppel-Like Factor 3 (KLF3/BKLF) Leads to Upregulation of the Insulin-Sensitizing Factor Adipolin (FAM132A/CTRP12/C1qdc2)
Open the PDF for Loss of Krüppel-Like Factor 3 (KLF3/BKLF) Leads to Upregulation of the Insulin-Sensitizing Factor Adipolin (FAM132A/CTRP12/C1qdc2) in another window
Journal Articles

Identification of BMP and Activin Membrane-Bound Inhibitor (BAMBI) as a Potent Negative Regulator of Adipogenesis and Modulator of Autocrine/Paracrine Adipogenic Factors

Xiao Luo, Louise J. Hutley, Julie A. Webster, Yu-Hee Kim, Dong-Fang Liu, Felicity S. Newell, Charlotte H. Widberg, Anthony Bachmann, Nigel Turner, Carsten Schmitz-Peiffer, Johannes B. Prins, Gong-She Yang, Jonathan P. Whitehead
Journal: Diabetes
Diabetes 2012;61(1):124–136
https://doi.org/10.2337/db11-0998
Published: 12 December 2011
View articletitled, Identification of BMP and Activin Membrane-Bound Inhibitor (BAMBI) as a Potent Negative Regulator of Adipogenesis and Modulator of Autocrine/Paracrine Adipogenic Factors
Open the PDF for Identification of BMP and Activin Membrane-Bound Inhibitor (BAMBI) as a Potent Negative Regulator of Adipogenesis and Modulator of Autocrine/Paracrine Adipogenic Factors in another window
Includes: Supplementary data
Journal Articles

High-Throughput Assay for Modulators of Mitochondrial Membrane Potential Identifies a Novel Compound With Beneficial Effects on db/db Mice

Bei-Ying Qiu, Nigel Turner, Yuan-Yuan Li, Min Gu, Meng-Wei Huang, Fang Wu, Tao Pang, Fa-Jun Nan, Ji-Ming Ye, Jing-Ya Li, Jia Li
Journal: Diabetes
Diabetes 2010;59(1):256–265
https://doi.org/10.2337/db09-0223
Published: 15 October 2009
View articletitled, High-Throughput Assay for Modulators of Mitochondrial Membrane Potential Identifies a Novel Compound With Beneficial Effects on db/db Mice
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Includes: Supplementary data
Journal Articles

Enhancement of Muscle Mitochondrial Oxidative Capacity and Alterations in Insulin Action Are Lipid Species Dependent: Potent Tissue-Specific Effects of Medium-Chain Fatty Acids

Nigel Turner, Krit Hariharan, Jennifer TidAng, Georgia Frangioudakis, Susan M. Beale, Lauren E. Wright, Xiao Yi Zeng, Simon J. Leslie, Jing-Ya Li, Edward W. Kraegen, Gregory J. Cooney, Ji-Ming Ye
Journal: Diabetes
Diabetes 2009;58(11):2547–2554
https://doi.org/10.2337/db09-0784
Published: 31 August 2009
View articletitled, Enhancement of Muscle Mitochondrial Oxidative Capacity and Alterations in Insulin Action Are Lipid Species Dependent: Potent Tissue-Specific Effects of Medium-Chain Fatty Acids
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Journal Articles

Overexpression of Carnitine Palmitoyltransferase-1 in Skeletal Muscle Is Sufficient to Enhance Fatty Acid Oxidation and Improve High-Fat Diet–Induced Insulin Resistance

Clinton R. Bruce, Andrew J. Hoy, Nigel Turner, Matthew J. Watt, Tamara L. Allen, Kevin Carpenter, Gregory J. Cooney, Mark A. Febbraio, Edward W. Kraegen
Journal: Diabetes
Diabetes 2009;58(3):550–558
https://doi.org/10.2337/db08-1078
Published: 01 March 2009
View articletitled, Overexpression of Carnitine Palmitoyltransferase-1 in Skeletal Muscle Is Sufficient to Enhance Fatty Acid Oxidation and Improve High-Fat Diet–Induced Insulin Resistance
Open the PDF for Overexpression of Carnitine Palmitoyltransferase-1 in Skeletal Muscle Is Sufficient to Enhance Fatty Acid Oxidation and Improve High-Fat Diet–Induced Insulin Resistance in another window
Includes: Supplementary data
Journal Articles

Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I: A Mechanism for the Action of Berberine to Activate AMP-Activated Protein Kinase and Improve Insulin Action

Nigel Turner, Jing-Ya Li, Alison Gosby, Sabrina W.C. To, Zhe Cheng, Hiroyuki Miyoshi, Makoto M. Taketo, Gregory J. Cooney, Edward W. Kraegen, David E. James, Li-Hong Hu, Jia Li, Ji-Ming Ye
Journal: Diabetes
Diabetes 2008;57(5):1414–1418
https://doi.org/10.2337/db07-1552
Published: 01 May 2008
View articletitled, Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I: A Mechanism for the Action of Berberine to Activate AMP-Activated Protein Kinase and Improve Insulin Action
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Includes: Supplementary data
Journal Articles

Excess Lipid Availability Increases Mitochondrial Fatty Acid Oxidative Capacity in Muscle: Evidence Against a Role for Reduced Fatty Acid Oxidation in Lipid-Induced Insulin Resistance in Rodents

Nigel Turner, Clinton R. Bruce, Susan M. Beale, Kyle L. Hoehn, Trina So, Michael S. Rolph, Gregory J. Cooney
Journal: Diabetes
Diabetes 2007;56(8):2085–2092
https://doi.org/10.2337/db07-0093
Published: 01 August 2007
View articletitled, Excess Lipid Availability Increases Mitochondrial Fatty Acid Oxidative Capacity in Muscle: Evidence Against a Role for Reduced Fatty Acid Oxidation in Lipid-Induced Insulin Resistance in Rodents
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Journal Articles

Genetic Ablation of the c-Cbl Ubiquitin Ligase Domain Results in Increased Energy Expenditure and Improved Insulin Action

Juan C. Molero, Nigel Turner, Christine B.F. Thien, Wallace Y. Langdon, David E. James, Gregory J. Cooney
Journal: Diabetes
Diabetes 2006;55(12):3411–3417
https://doi.org/10.2337/db06-0955
Published: 01 December 2006
View articletitled, Genetic Ablation of the c-Cbl Ubiquitin Ligase Domain Results in Increased Energy Expenditure and Improved Insulin Action
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Includes: Supplementary data
Journal Articles

Casitas b-Lineage Lymphoma–Deficient Mice Are Protected Against High-Fat Diet–Induced Obesity and Insulin Resistance

Juan C. Molero, Samuel G. Waring, Adrian Cooper, Nigel Turner, Ross Laybutt, Gregory J. Cooney, David E. James
Journal: Diabetes
Diabetes 2006;55(3):708–715
https://doi.org/10.2337/diabetes.55.03.06.db05-0312
Published: 01 March 2006
View articletitled, Casitas b-Lineage Lymphoma–Deficient Mice Are Protected Against High-Fat Diet–Induced Obesity and Insulin Resistance
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