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Patrick Gilon
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Journal Articles

Impaired Store-Operated Calcium Entry and STIM1 Loss Lead to Reduced Insulin Secretion and Increased Endoplasmic Reticulum Stress in the Diabetic β-Cell

Tatsuyoshi Kono, Xin Tong, Solaema Taleb, Robert N. Bone, Hitoshi Iida, Chih-Chun Lee, Paul Sohn, Patrick Gilon, Michael W. Roe, Carmella Evans-Molina
Journal: Diabetes
Diabetes 2018;67(11):2293–2304
https://doi.org/10.2337/db17-1351
Published: 21 August 2018
View article titled, Impaired Store-Operated Calcium Entry and STIM1 Loss Lead to Reduced Insulin Secretion and Increased Endoplasmic Reticulum Stress in the Diabetic β-Cell
Open the PDF for Impaired Store-Operated Calcium Entry and STIM1 Loss Lead to Reduced Insulin Secretion and Increased Endoplasmic Reticulum Stress in the Diabetic β-Cell in another window
Includes: Supplementary data
Journal Articles

Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of KATP Channel Blockers

Bao-Khanh Lai, Heeyoung Chae, Ana Gómez-Ruiz, Panpan Cheng, Paola Gallo, Nancy Antoine, Christophe Beauloye, Jean-Christophe Jonas, Victor Seghers, Susumu Seino, Patrick Gilon
Journal: Diabetes
Diabetes 2018;67(11):2239–2253
https://doi.org/10.2337/db17-0880
Published: 16 August 2018
View article titled, Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of K<sub>ATP</sub> Channel Blockers
Open the PDF for Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of K<sub>ATP</sub> Channel Blockers in another window
Includes: Supplementary data
Journal Articles

SERCA2 Deficiency Impairs Pancreatic β-Cell Function in Response to Diet-Induced Obesity

Xin Tong, Tatsuyoshi Kono, Emily K. Anderson-Baucum, Wataru Yamamoto, Patrick Gilon, Djamel Lebeche, Richard N. Day, Gary E. Shull, Carmella Evans-Molina
Journal: Diabetes
Diabetes 2016;65(10):3039–3052
https://doi.org/10.2337/db16-0084
Published: 03 August 2016
View article titled, SERCA2 Deficiency Impairs Pancreatic β-Cell Function in Response to Diet-Induced Obesity
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Includes: Supplementary data
Journal Articles

UCP2 Regulates the Glucagon Response to Fasting and Starvation

Emma M. Allister, Christine A. Robson-Doucette, Kacey J. Prentice, Alexandre B. Hardy, Sobia Sultan, Herbert Y. Gaisano, Dong Kong, Patrick Gilon, Pedro L. Herrera, Bradford B. Lowell, Michael B. Wheeler
Journal: Diabetes
Diabetes 2013;62(5):1623–1633
https://doi.org/10.2337/db12-0981
Published: 16 April 2013
View article titled, UCP2 Regulates the Glucagon Response to Fasting and Starvation
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Includes: Supplementary data
Journal Articles

Tolbutamide Controls Glucagon Release From Mouse Islets Differently Than Glucose: Involvement of KATP Channels From Both α-Cells and δ-Cells

Rui Cheng-Xue, Ana Gómez-Ruiz, Nancy Antoine, Laura A. Noël, Hee-Young Chae, Magalie A. Ravier, Fabrice Chimienti, Frans C. Schuit, Patrick Gilon
Journal: Diabetes
Diabetes 2013;62(5):1612–1622
https://doi.org/10.2337/db12-0347
Published: 16 April 2013
View article titled, Tolbutamide Controls Glucagon Release From Mouse Islets Differently Than Glucose: <subtitle>Involvement of K<sub>ATP</sub> Channels From Both α-Cells and δ-Cells</subtitle>
Open the PDF for Tolbutamide Controls Glucagon Release From Mouse Islets Differently Than Glucose: <subtitle>Involvement of K<sub>ATP</sub> Channels From Both α-Cells and δ-Cells</subtitle> in another window
Includes: Supplementary data
Journal Articles

In Situ Electrophysiological Examination of Pancreatic α Cells in the Streptozotocin-Induced Diabetes Model, Revealing the Cellular Basis of Glucagon Hypersecretion

Ya-Chi Huang, Marjan S. Rupnik, Negar Karimian, Pedro L. Herrera, Patrick Gilon, Zhong-Ping Feng, Herbert Y. Gaisano
Journal: Diabetes
Diabetes 2013;62(2):519–530
https://doi.org/10.2337/db11-0786
Published: 17 January 2013
View article titled, In Situ Electrophysiological Examination of Pancreatic α Cells in the Streptozotocin-Induced Diabetes Model, Revealing the Cellular Basis of Glucagon Hypersecretion
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Journal Articles

Mechanisms of Control of the Free Ca2+ Concentration in the Endoplasmic Reticulum of Mouse Pancreatic β-Cells: Interplay With Cell Metabolism and [Ca2+]c and Role of SERCA2b and SERCA3

Magalie A. Ravier, Dorothée Daro, Leticia Prates Roma, Jean-Christophe Jonas, Rui Cheng-Xue, Frans C. Schuit, Patrick Gilon
Journal: Diabetes
Diabetes 2011;60(10):2533–2545
https://doi.org/10.2337/db10-1543
Published: 16 September 2011
View article titled, Mechanisms of Control of the Free Ca<sup>2+</sup> Concentration in the Endoplasmic Reticulum of Mouse Pancreatic β-Cells: <subtitle>Interplay With Cell Metabolism and [Ca<sup>2+</sup>]<sub>c</sub> and Role of SERCA2b and SERCA3</subtitle>
Open the PDF for Mechanisms of Control of the Free Ca<sup>2+</sup> Concentration in the Endoplasmic Reticulum of Mouse Pancreatic β-Cells: <subtitle>Interplay With Cell Metabolism and [Ca<sup>2+</sup>]<sub>c</sub> and Role of SERCA2b and SERCA3</subtitle> in another window
Includes: Supplementary data
Journal Articles

Glucose and Pharmacological Modulators of ATP-Sensitive K+ Channels Control [Ca2+]c by Different Mechanisms in Isolated Mouse α-Cells

Nicolas Quoix, Rui Cheng-Xue, Laurine Mattart, Ziad Zeinoun, Yves Guiot, Mélanie C. Beauvois, Jean-Claude Henquin, Patrick Gilon
Journal: Diabetes
Diabetes 2009;58(2):412–421
https://doi.org/10.2337/db07-1298
Published: 01 February 2009
View article titled, Glucose and Pharmacological Modulators of ATP-Sensitive K<sup>+</sup> Channels Control [Ca<sup>2+</sup>]<sub>c</sub> by Different Mechanisms in Isolated Mouse α-Cells
Open the PDF for Glucose and Pharmacological Modulators of ATP-Sensitive K<sup>+</sup> Channels Control [Ca<sup>2+</sup>]<sub>c</sub> by Different Mechanisms in Isolated Mouse α-Cells in another window
Includes: Supplementary data
Journal Articles

SERCA3 Ablation Does Not Impair Insulin Secretion but Suggests Distinct Roles of Different Sarcoendoplasmic Reticulum Ca2+ Pumps for Ca2+ Homeostasis in Pancreatic β-cells

Abdelilah Arredouani, Yves Guiot, Jean-Christophe Jonas, Lynne H. Liu, Myriam Nenquin, José A. Pertusa, Jacques Rahier, Jean-François Rolland, Gary E. Shull, Martine Stevens, Frank Wuytack, Jean-Claude Henquin, Patrick Gilon
Journal: Diabetes
Diabetes 2002;51(11):3245–3253
https://doi.org/10.2337/diabetes.51.11.3245
Published: 01 November 2002
View article titled, SERCA3 Ablation Does Not Impair Insulin Secretion but Suggests Distinct Roles of Different Sarcoendoplasmic Reticulum Ca<sup>2+</sup> Pumps for Ca<sup>2+</sup> Homeostasis in Pancreatic β-cells
Open the PDF for SERCA3 Ablation Does Not Impair Insulin Secretion but Suggests Distinct Roles of Different Sarcoendoplasmic Reticulum Ca<sup>2+</sup> Pumps for Ca<sup>2+</sup> Homeostasis in Pancreatic β-cells in another window
Journal Articles

Control Mechanisms of the Oscillations of Insulin Secretion In Vitro and In Vivo

Patrick Gilon, Magalie A. Ravier, Jean-Christophe Jonas, Jean-Claude Henquin
Journal: Diabetes
Diabetes 2002;51(suppl_1):S144–S151
https://doi.org/10.2337/diabetes.51.2007.S144
Published: 01 February 2002
View article titled, Control Mechanisms of the Oscillations of Insulin Secretion In Vitro and In Vivo
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Journal Articles

Feedback Control of the ATP-Sensitive K+ Current by Cytosolic Ca2+ Contributes to Oscillations of the Membrane Potential in Pancreatic β-Cells

Jean-François Rolland, Jean-Claude Henquin, Patrick Gilon
Journal: Diabetes
Diabetes 2002;51(2):376–384
https://doi.org/10.2337/diabetes.51.2.376
Published: 01 February 2002
View article titled, Feedback Control of the ATP-Sensitive K<sup>+</sup> Current by Cytosolic Ca<sup>2+</sup> Contributes to Oscillations of the Membrane Potential in Pancreatic β-Cells
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Journal Articles

Temporal and Quantitative Correlations Between Insulin Secretion and Stably Elevated or Oscillatory Cytoplasmic Ca2+ in Mouse Pancreatic β-Cells

Jean-Christophe Jonas, Patrick Gilon, Jean-Claude Henquin
Journal: Diabetes
Diabetes 1998;47(8):1266–1273
https://doi.org/10.2337/diab.47.8.1266
Published: 01 August 1998
View article titled, Temporal and Quantitative Correlations Between Insulin Secretion and Stably Elevated or Oscillatory Cytoplasmic Ca<sup>2+</sup> in Mouse Pancreatic β-Cells
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Journal Articles

Mechanisms of the Stimulation of Insulin Release by Saturated Fatty Acids: A Study of Palmitate Effects in Mouse β-cells

Catherine Warnotte, Patrick Gilon, Myriam Nenquin, Jean-Claude Henquin
Journal: Diabetes
Diabetes 1994;43(5):703–711
https://doi.org/10.2337/diab.43.5.703
Published: 01 May 1994
View article titled, Mechanisms of the Stimulation of Insulin Release by Saturated Fatty Acids: A Study of Palmitate Effects in Mouse β-cells
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