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Paul Fernyhough
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Journal Articles

Amelioration of Both Central and Peripheral Neuropathy in Mouse Models of Type 1 and Type 2 Diabetes by the Neurogenic Molecule NSI-189

Corinne G. Jolivalt, Alexandra Marquez, David Quach, Michelle C. Navarro Diaz, Carlos Anaya, Betelhem Kifle, Nabeel Muttalib, Gabriela Sanchez, Lucy Guernsey, Mike Hefferan, Darrel R. Smith, Paul Fernyhough, Karl Johe, Nigel A. Calcutt
Journal: Diabetes
Diabetes 2019;68(11):2143–2154
https://doi.org/10.2337/db19-0271
Published: 06 September 2019
View article titled, Amelioration of Both Central and Peripheral Neuropathy in Mouse Models of Type 1 and Type 2 Diabetes by the Neurogenic Molecule NSI-189
Open the PDF for Amelioration of Both Central and Peripheral Neuropathy in Mouse Models of Type 1 and Type 2 Diabetes by the Neurogenic Molecule NSI-189 in another window
Includes: Supplementary data
Meeting Abstracts

Muscarinic Receptor Antagonist Improves Nerve Fiber Function in Subjects with Type 2 Diabetes and Peripheral Neuropathy

AARON I. VINIK, NIGEL A. CALCUTT, JOSHUA F. EDWARDS, JESSICA R. WEAVER, MICHAEL D. BAILEY, PAUL FERNYHOUGH, LINDSEY B. CUNDRA, KATIE E. FRIZZI, HENRI PARSON, CAROLINA M. CASELLINI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):58-OR
https://doi.org/10.2337/db18-58-OR
Published: 01 July 2018
View article titled, Muscarinic Receptor Antagonist Improves Nerve Fiber Function in Subjects with Type 2 Diabetes and Peripheral Neuropathy
Journal Articles

Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats

Eli Akude, Elena Zherebitskaya, Subir K. Roy Chowdhury, Darrell R. Smith, Rick T. Dobrowsky, Paul Fernyhough
Journal: Diabetes
Diabetes 2011;60(1):288–297
https://doi.org/10.2337/db10-0818
Published: 28 September 2010
View article titled, Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats
Open the PDF for Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats in another window
Includes: Supplementary data
Journal Articles

Mitochondrial Respiratory Chain Dysfunction in Dorsal Root Ganglia of Streptozotocin-Induced Diabetic Rats and Its Correction by Insulin Treatment

Subir K. Roy Chowdhury, Elena Zherebitskaya, Darrell R. Smith, Eli Akude, Sharmila Chattopadhyay, Corinne G. Jolivalt, Nigel A. Calcutt, Paul Fernyhough
Journal: Diabetes
Diabetes 2010;59(4):1082–1091
https://doi.org/10.2337/db09-1299
Published: 26 January 2010
View article titled, Mitochondrial Respiratory Chain Dysfunction in Dorsal Root Ganglia of Streptozotocin-Induced Diabetic Rats and Its Correction by Insulin Treatment
Open the PDF for Mitochondrial Respiratory Chain Dysfunction in Dorsal Root Ganglia of Streptozotocin-Induced Diabetic Rats and Its Correction by Insulin Treatment in another window
Includes: Supplementary data
Journal Articles

Development of Selective Axonopathy in Adult Sensory Neurons Isolated From Diabetic Rats: Role of Glucose-Induced Oxidative Stress

Elena Zherebitskaya, Eli Akude, Darrell R. Smith, Paul Fernyhough
Journal: Diabetes
Diabetes 2009;58(6):1356–1364
https://doi.org/10.2337/db09-0034
Published: 27 February 2009
View article titled, Development of Selective Axonopathy in Adult Sensory Neurons Isolated From Diabetic Rats: <subtitle>Role of Glucose-Induced Oxidative Stress</subtitle>
Open the PDF for Development of Selective Axonopathy in Adult Sensory Neurons Isolated From Diabetic Rats: <subtitle>Role of Glucose-Induced Oxidative Stress</subtitle> in another window
Includes: Supplementary data
Journal Articles

Distal Degenerative Sensory Neuropathy in a Long-Term Type 2 Diabetes Rat Model

Valentine Brussee, GuiFang Guo, YingYing Dong, Chu Cheng, José A. Martinez, Darrell Smith, Gordon W. Glazner, Paul Fernyhough, Douglas W. Zochodne
Journal: Diabetes
Diabetes 2008;57(6):1664–1673
https://doi.org/10.2337/db07-1737
Published: 01 June 2008
View article titled, Distal Degenerative Sensory Neuropathy in a Long-Term Type 2 Diabetes Rat Model
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Journal Articles

Neurotrophin-3 Prevents the Proximal Accumulation of Neurofilament Proteins in Sensory Neurons of Streptozocin-Induced Diabetic Rats

Nicola M. Sayers, Lisa J. Beswick, Alicia Middlemas, Nigel A. Calcutt, Andrew P. Mizisin, David R. Tomlinson, Paul Fernyhough
Journal: Diabetes
Diabetes 2003;52(9):2372–2380
https://doi.org/10.2337/diabetes.52.9.2372
Published: 01 September 2003
View article titled, Neurotrophin-3 Prevents the Proximal Accumulation of Neurofilament Proteins in Sensory Neurons of Streptozocin-Induced Diabetic Rats
Open the PDF for Neurotrophin-3 Prevents the Proximal Accumulation of Neurofilament Proteins in Sensory Neurons of Streptozocin-Induced Diabetic Rats in another window
Journal Articles

Insulin Prevents Depolarization of the Mitochondrial Inner Membrane in Sensory Neurons of Type 1 Diabetic Rats in the Presence of Sustained Hyperglycemia

Tze-Jen Huang, Sally A. Price, Lucy Chilton, Nigel A. Calcutt, David R. Tomlinson, Alex Verkhratsky, Paul Fernyhough
Journal: Diabetes
Diabetes 2003;52(8):2129–2136
https://doi.org/10.2337/diabetes.52.8.2129
Published: 01 August 2003
View article titled, Insulin Prevents Depolarization of the Mitochondrial Inner Membrane in Sensory Neurons of Type 1 Diabetic Rats in the Presence of Sustained Hyperglycemia
Open the PDF for Insulin Prevents Depolarization of the Mitochondrial Inner Membrane in Sensory Neurons of Type 1 Diabetic Rats in the Presence of Sustained Hyperglycemia in another window
Journal Articles

Reduced Levels of mRNA Encoding Endoskeletal and Growth-Associated Proteins in Sensory Ganglia in Experimental Diabetes

Liza Mohiuddin, Paul Fernyhough, David R Tomlinson
Journal: Diabetes
Diabetes 1995;44(1):25–30
https://doi.org/10.2337/diab.44.1.25
Published: 01 January 1995
View article titled, Reduced Levels of mRNA Encoding Endoskeletal and Growth-Associated Proteins in Sensory Ganglia in Experimental Diabetes
Open the PDF for Reduced Levels of mRNA Encoding Endoskeletal and Growth-Associated Proteins in Sensory Ganglia in Experimental Diabetes in another window