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Meeting Abstracts

1728-P: Transcriptional Activation of Myc by Glucose Requires Recruitment of ChREBP to the Pvt1 Promoter Regulating Proliferation in ß-Cells

LIORA S. KATZ, PENG WANG, GABRIEL BRILL, PILI ZHANG, JONATHAN HALDEMAN, CHRISTOPHER B. NEWGARD, ANDREW F. STEWART, ADOLFO GARCIA-OCANA, DONALD SCOTT
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1728-P
https://doi.org/10.2337/db23-1728-P
Published: 20 June 2023
View articletitled, 1728-P: Transcriptional Activation of Myc by Glucose Requires Recruitment of ChREBP to the Pvt1 Promoter Regulating Proliferation in ß-Cells
Meeting Abstracts

349-OR: Selected DYRK1A Inhibitors Simultaneously Drive Both Human Beta-Cell Proliferation and Differentiation

PENG WANG, KUNAL KUMAR, HONGTAO LIU, OLIVIA WOOD, ESRA KARAKOSE, LAURYN CHOLEVA, LUCA LAMBERTINI, ADOLFO GARCIA-OCANA, ROBERT J. DEVITA, ANDREW F. STEWART
Journal: Diabetes
Diabetes 2023;72(Supplement_1):349-OR
https://doi.org/10.2337/db23-349-OR
Published: 20 June 2023
View articletitled, 349-OR: Selected DYRK1A Inhibitors Simultaneously Drive Both Human Beta-Cell Proliferation and Differentiation
Meeting Abstracts

1723-P: Dual-Label Kinetic Assay to Monitor ß-Cell Death and Proliferation

LIORA S. KATZ, PENG WANG, HUSNU U. KANISKAN, JESSE D. GELLES, JERRY EDWARD CHIPUK, ANDREW F. STEWART, DONALD SCOTT
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1723-P
https://doi.org/10.2337/db23-1723-P
Published: 20 June 2023
View articletitled, 1723-P: Dual-Label Kinetic Assay to Monitor ß-Cell Death and Proliferation
Meeting Abstracts

84-OR: Structure–Function Analysis of p57KIP2 in the Human Pancreatic Beta Cell Reveals a Canonical Bipartite Nuclear Localization Sequence (NLS)

LAURYN CHOLEVA, PENG WANG, HONGTAO LIU, OLIVIA WOOD, LUCA LAMBERTINI, ESRA KARAKOSE, ANDREW F. STEWART
Journal: Diabetes
Diabetes 2023;72(Supplement_1):84-OR
https://doi.org/10.2337/db23-84-OR
Published: 20 June 2023
View articletitled, 84-OR: Structure–Function Analysis of p57KIP2 in the Human Pancreatic Beta Cell Reveals a Canonical Bipartite Nuclear Localization Sequence (NLS)
Meeting Abstracts

822-P: The Harmine and Exendin4 Combination Markedly Expands Human Beta-Cell Mass In Vivo in Diabetic Mice

KARA A. BELIARD, CAROLINA ROSSELOT, YANSUI LI, ALEXANDRA ALVARSSON, PENG WANG, KEYA THAKKAR, DANIELA GUEVARA, ROBERT J. DEVITA, ANDREW F. STEWART, SARAH STANLEY, ADOLFO GARCIA-OCANA
Journal: Diabetes
Diabetes 2022;71(Supplement_1):822-P
https://doi.org/10.2337/db22-822-P
Published: 01 June 2022
View articletitled, 822-P: The Harmine and Exendin4 Combination Markedly Expands Human Beta-Cell Mass In Vivo in Diabetic Mice
Meeting Abstracts

14-OR: Harmine and Exenatide Combination Increases Human ß-Cell Survival

CAROLINA ROSSELOT, YANSUI LI, DANIELA GUEVARA, KARA A. BELIARD, RANDY KANG, PENG WANG, KEYA THAKKAR, GEMING LU, ROBERT J. DEVITA, ANDREW F. STEWART, ADOLFO GARCIA-OCANA
Journal: Diabetes
Diabetes 2022;71(Supplement_1):14-OR
https://doi.org/10.2337/db22-14-OR
Published: 01 June 2022
View articletitled, 14-OR: Harmine and Exenatide Combination Increases Human ß-Cell Survival
Meeting Abstracts

10-OR: Combination Therapy with Anti-CD3 Antibody and Harmine plus Exendin-4 Enhances Remission from Recent-Onset Type 1 Diabetes.

GEMING LU, RANDY KANG, YANSUI LI, PENG WANG, CAROLINA ROSSELOT, ROBERT J. DEVITA, ANDREW F. STEWART, ADOLFO GARCIA-OCANA
Journal: Diabetes
Diabetes 2022;71(Supplement_1):10-OR
https://doi.org/10.2337/db22-10-OR
Published: 01 June 2022
View articletitled, 10-OR: Combination Therapy with Anti-CD3 Antibody and Harmine plus Exendin-4 Enhances Remission from Recent-Onset Type 1 Diabetes.
Meeting Abstracts

44-OR: Human Pseudo Islets Reveal Differential Effects of Gq Signaling in ß Cells in Low and High Glucose

JOHN T. WALKER, RACHANA HALIYUR, RADHIKA ARAMANDLA, GREG POFFENBERGER, HEATHER A. NELSON, JOSEPH LUCHSINGER, PENG WANG, ADOLFO GARCIA-OCAÑA, MARCELA BRISSOVA, ALVIN C. POWERS
Journal: Diabetes
Diabetes 2019;68(Supplement_1):44-OR
https://doi.org/10.2337/db19-44-OR
Published: 01 June 2019
View articletitled, 44-OR: Human Pseudo Islets Reveal Differential Effects of Gq Signaling in ß Cells in Low and High Glucose
Meeting Abstracts

Gestational Diabetes and Diabetes and Prediabetes Risks Postpartum—A Large Observational Study

YUN SHEN, PENG WANG, LEISHEN WANG, SHUANG ZHANG, HUIKUN LIU, WEIQIN LI, NAN LI, WEI LI, JUNHONG LENG, JING WANG, HUIGUANG TIAN, CUILIN ZHANG, XILIN YANG, ZHIJIE M. YU, GANG HU
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1433-P
https://doi.org/10.2337/db18-1433-P
Published: 01 July 2018
View articletitled, Gestational Diabetes and Diabetes and Prediabetes Risks Postpartum—A Large Observational Study
Journal Articles

Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells

Hainan Chen, Jeffrey W. Kleinberger, Karen K. Takane, Fatimah Salim, Nathalie Fiaschi-Taesch, Kyrie Pappas, Ramon Parsons, Jing Jiang, Yue Zhang, Hongtao Liu, Peng Wang, Aaron S. Bender, Stuart J. Frank, Andrew F. Stewart
Journal: Diabetes
Diabetes 2015;64(11):3784–3797
https://doi.org/10.2337/db15-0083
Published: 09 July 2015
View articletitled, Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells
Open the PDF for Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells in another window
Includes: Supplementary data
Journal Articles

Enhancement of Hypothalamic STAT3 Acetylation by Nuclear Receptor Nur77 Dictates Leptin Sensitivity

Yan Chen, Rong Wu, Hang-zi Chen, Qian Xiao, Wei-jia Wang, Jian-ping He, Xiao-xue Li, Xian-wen Yu, Li Li, Peng Wang, Xi-chen Wan, Xin-hua Tian, Shu-jing Li, Xiang Yu, Qiao Wu
Journal: Diabetes
Diabetes 2015;64(6):2069–2081
https://doi.org/10.2337/db14-1206
Published: 09 January 2015
View articletitled, Enhancement of Hypothalamic STAT3 Acetylation by Nuclear Receptor Nur77 Dictates Leptin Sensitivity
Open the PDF for Enhancement of Hypothalamic STAT3 Acetylation by Nuclear Receptor Nur77 Dictates Leptin Sensitivity in another window
Includes: Supplementary data