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Perrin Guyer
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Journal Articles

CD4+ T Cells From Individuals With Type 1 Diabetes Respond to a Novel Class of Deamidated Peptides Formed in Pancreatic Islets

Aïsha Callebaut, Perrin Guyer, Rita Derua, Mijke Buitinga, Anthony Manganaro, Xiaoyan Yi, Fernanda Marques Câmara Sodré, Saurabh Vig, Mara Suleiman, Piero Marchetti, Decio L. Eizirik, Sally C. Kent, Chantal Mathieu, Eddie A. James, Lut Overbergh
Journal: Diabetes
Diabetes 2024;73(5):728–742
https://doi.org/10.2337/db23-0588
Published: 22 February 2024
View article titled, CD4<sup>+</sup> T Cells From Individuals With Type 1 Diabetes Respond to a Novel Class of Deamidated Peptides Formed in Pancreatic Islets
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Journal Articles

An Insulin-Chromogranin A Hybrid Peptide Activates DR11-Restricted T Cells in Human Type 1 Diabetes

Aïsha Callebaut, Perrin Guyer, Rocky L. Baker, Joylynn B. Gallegos, Anita C. Hohenstein, Peter A. Gottlieb, Chantal Mathieu, Lut Overbergh, Kathryn Haskins, Eddie A. James
Journal: Diabetes
Diabetes 2024;73(5):743–750
https://doi.org/10.2337/db23-0622
Published: 31 January 2024
View article titled, An Insulin-Chromogranin A Hybrid Peptide Activates DR11-Restricted T Cells in Human Type 1 Diabetes
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Journal Articles

Recognition of mRNA Splice Variant and Secretory Granule Epitopes by CD4+ T Cells in Type 1 Diabetes

Perrin Guyer, David Arribas-Layton, Anthony Manganaro, Cate Speake, Sandra Lord, Decio L. Eizirik, Sally C. Kent, Roberto Mallone, Eddie A. James
Journal: Diabetes
Diabetes 2023;72(1):85–96
https://doi.org/10.2337/db22-0191
Published: 06 October 2022
View article titled, Recognition of mRNA Splice Variant and Secretory Granule Epitopes by CD4<sup>+</sup> T Cells in Type 1 Diabetes
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Journal Articles

Carbonyl Posttranslational Modification Associated With Early-Onset Type 1 Diabetes Autoimmunity

Mei-Ling Yang, Sean E. Connolly, Renelle J. Gee, TuKiet T. Lam, Jean Kanyo, Jian Peng, Perrin Guyer, Farooq Syed, Hubert M. Tse, Steven G. Clarke, Catherine F. Clarke, Eddie A. James, Cate Speake, Carmella Evans-Molina, Peter Arvan, Kevan C. Herold, Li Wen, Mark J. Mamula
Journal: Diabetes
Diabetes 2022;71(9):1979–1993
https://doi.org/10.2337/db21-0989
Published: 22 June 2022
View article titled, Carbonyl Posttranslational Modification Associated With Early-Onset Type 1 Diabetes Autoimmunity
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Journal Articles

Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB1*04:01

David Arribas-Layton, Perrin Guyer, Thomas Delong, Mylinh Dang, I-Ting Chow, Cate Speake, Carla J. Greenbaum, William W. Kwok, Rocky L. Baker, Kathryn Haskins, Eddie A. James
Journal: Diabetes
Diabetes 2020;69(7):1492–1502
https://doi.org/10.2337/db19-0620
Published: 14 April 2020
View article titled, Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB1*04:01
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