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Peter Proks
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Journal Articles

The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion

Gregor Sachse, Elizabeth Haythorne, Thomas Hill, Peter Proks, Russell Joynson, Raul Terrón-Expósito, Liz Bentley, Stephen J. Tucker, Roger D. Cox, Frances M. Ashcroft
Journal: Diabetes
Diabetes 2021;70(5):1145–1156
https://doi.org/10.2337/db20-0691
Published: 10 February 2021
View article titled, The <em>KCNJ11-E23K</em> Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion
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Journal Articles

Molecular Mechanism of Sulphonylurea Block of KATP Channels Carrying Mutations That Impair ATP Inhibition and Cause Neonatal Diabetes

Peter Proks, Heidi de Wet, Frances M. Ashcroft
Journal: Diabetes
Diabetes 2013;62(11):3909–3919
https://doi.org/10.2337/db13-0531
Published: 18 October 2013
View article titled, Molecular Mechanism of Sulphonylurea Block of K<sub>ATP</sub> Channels Carrying Mutations That Impair ATP Inhibition and Cause Neonatal Diabetes
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Journal Articles

A Mouse Model of Human Hyperinsulinism Produced by the E1506K Mutation in the Sulphonylurea Receptor SUR1

Kenju Shimomura, Maija Tusa, Michaela Iberl, Melissa F. Brereton, Stephan Kaizik, Peter Proks, Carolina Lahmann, Nagendra Yaluri, Shalem Modi, Hanna Huopio, Jarkko Ustinov, Timo Otonkoski, Markku Laakso, Frances M. Ashcroft
Journal: Diabetes
Diabetes 2013;62(11):3797–3806
https://doi.org/10.2337/db12-1611
Published: 18 October 2013
View article titled, A Mouse Model of Human Hyperinsulinism Produced by the E1506K Mutation in the Sulphonylurea Receptor SUR1
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Includes: Supplementary data
Journal Articles

Mosaic Paternal Uniparental Isodisomy and an ABCC8 Gene Mutation in a Patient With Permanent Neonatal Diabetes and Hemihypertrophy

Julian P.H. Shield, Sarah E. Flanagan, Deborah J. Mackay, Lorna W. Harries, Peter Proks, Christophe Girard, Frances M. Ashcroft, I. Karen Temple, Sian Ellard
Journal: Diabetes
Diabetes 2008;57(1):255–258
https://doi.org/10.2337/db07-0999
Published: 01 January 2008
View article titled, Mosaic Paternal Uniparental Isodisomy and an <em>ABCC8</em> Gene Mutation in a Patient With Permanent Neonatal Diabetes and Hemihypertrophy
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Journal Articles

Functional Effects of Mutations at F35 in the NH2-terminus of Kir6.2 (KCNJ11), Causing Neonatal Diabetes, and Response to Sulfonylurea Therapy

Peter Proks, Christophe Girard, Halvor Bævre, Pål R. Njølstad, Frances M. Ashcroft
Journal: Diabetes
Diabetes 2006;55(6):1731–1737
https://doi.org/10.2337/db05-1420
Published: 01 June 2006
View article titled, Functional Effects of Mutations at F35 in the NH<sub>2</sub>-terminus of Kir6.2 (<em>KCNJ11</em>), Causing Neonatal Diabetes, and Response to Sulfonylurea Therapy
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Includes: Supplementary data
Journal Articles

Mutations at the Same Residue (R50) of Kir6.2 (KCNJ11) That Cause Neonatal Diabetes Produce Different Functional Effects

Kenju Shimomura, Christophe A.J. Girard, Peter Proks, Joanna Nazim, Jonathan D. Lippiat, Franco Cerutti, Renata Lorini, Sian Ellard, Andrew T. Hattersley, Fabrizio Barbetti, Frances M. Ashcroft
Journal: Diabetes
Diabetes 2006;55(6):1705–1712
https://doi.org/10.2337/db05-1640
Published: 01 June 2006
View article titled, Mutations at the Same Residue (R50) of Kir6.2 (<em>KCNJ11</em>) That Cause Neonatal Diabetes Produce Different Functional Effects
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Journal Articles

Identification of a Functionally Important Negatively Charged Residue Within the Second Catalytic Site of the SUR1 Nucleotide-Binding Domains

Jeff D. Campbell, Peter Proks, Jonathan D. Lippiat, Mark S.P. Sansom, Frances M. Ashcroft
Journal: Diabetes
Diabetes 2004;53(suppl_3):S123–S127
https://doi.org/10.2337/diabetes.53.suppl_3.S123
Published: 01 December 2004
View article titled, Identification of a Functionally Important Negatively Charged Residue Within the Second Catalytic Site of the SUR1 Nucleotide-Binding Domains
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Journal Articles

Sulfonylurea Stimulation of Insulin Secretion

Peter Proks, Frank Reimann, Nick Green, Fiona Gribble, Frances Ashcroft
Journal: Diabetes
Diabetes 2002;51(suppl_3):S368–S376
https://doi.org/10.2337/diabetes.51.2007.S368
Published: 01 December 2002
View article titled, Sulfonylurea Stimulation of Insulin Secretion
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