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Philippe A Halban
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Journal Articles

Erratum. Small Interfering RNA—Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture. Diabetes 2008;57: 3045—3055

Lucy Marzban, Alejandra Tomas, Thomas C. Becker, Lawrence Rosenberg, Jose Oberholzer, Paul E. Fraser, Philippe A. Halban, C. Bruce Verchere
Journal: Diabetes
Diabetes 2016;65(3):818
https://doi.org/10.2337/db16-er03
Published: 13 February 2016
View article titled, Erratum. Small Interfering RNA—Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture. Diabetes 2008;57: 3045—3055
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Journal Articles

Bimodal Effect on Pancreatic β-Cells of Secretory Products From Normal or Insulin-Resistant Human Skeletal Muscle. Diabetes 2011;60: 1111–1121

Karim Bouzakri, Peter Plomgaard, Thierry Berney, Marc Y. Donath, Bente Karlund Pedersen, Philippe A. Halban
Journal: Diabetes
Diabetes 2015;64(1):312
https://doi.org/10.2337/db15-er01a
Published: 16 December 2014
View article titled, Bimodal Effect on Pancreatic β-Cells of Secretory Products From Normal or Insulin-Resistant Human Skeletal Muscle. Diabetes 2011;60: 1111–1121
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Journal Articles

Bimodal Effect on Pancreatic β-Cells of Secretory Products From Normal or Insulin-Resistant Human Skeletal Muscle

Karim Bouzakri, Peter Plomgaard, Thierry Berney, Marc Y. Donath, Bente Karlund Pedersen, Philippe A. Halban
Journal: Diabetes
Diabetes 2011;60(4):1111–1121
https://doi.org/10.2337/db10-1178
Published: 22 March 2011
View article titled, Bimodal Effect on Pancreatic β-Cells of Secretory Products From Normal or Insulin-Resistant Human Skeletal Muscle
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Journal Articles

Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin

Dieter Rondas, Alejandra Tomas, Philippe A. Halban
Journal: Diabetes
Diabetes 2011;60(4):1146–1157
https://doi.org/10.2337/db10-0946
Published: 22 March 2011
View article titled, Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin
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Journal Articles

Small Interfering RNA–Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture

Lucy Marzban, Alejandra Tomas, Thomas C. Becker, Lawrence Rosenberg, Jose Oberholzer, Paul E. Fraser, Philippe A. Halban, C. Bruce Verchere
Journal: Diabetes
Diabetes 2008;57(11):3045–3055
https://doi.org/10.2337/db08-0485
Published: 01 November 2008
View article titled, Small Interfering RNA–Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture
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Journal Articles

Rab GTPase-Activating Protein AS160 Is a Major Downstream Effector of Protein Kinase B/Akt Signaling in Pancreatic β-Cells

Karim Bouzakri, Pascale Ribaux, Alejandra Tomas, Geraldine Parnaud, Katharina Rickenbach, Philippe A. Halban
Journal: Diabetes
Diabetes 2008;57(5):1195–1204
https://doi.org/10.2337/db07-1469
Published: 01 May 2008
View article titled, Rab GTPase-Activating Protein AS160 Is a Major Downstream Effector of Protein Kinase B/Akt Signaling in Pancreatic β-Cells
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Includes: Supplementary data
Journal Articles

Increasing GLP-1–Induced β-Cell Proliferation by Silencing the Negative Regulators of Signaling cAMP Response Element Modulator-α and DUSP14

Sonia Klinger, Carine Poussin, Marie-Bernard Debril, Wanda Dolci, Philippe A. Halban, Bernard Thorens
Journal: Diabetes
Diabetes 2008;57(3):584–593
https://doi.org/10.2337/db07-1414
Published: 01 March 2008
View article titled, Increasing GLP-1–Induced β-Cell Proliferation by Silencing the Negative Regulators of Signaling cAMP Response Element Modulator-α and DUSP14
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Includes: Supplementary data
Journal Articles

Dominant-Negative Effects of a Novel Mutated Ins2 Allele Causes Early-Onset Diabetes and Severe β-Cell Loss in Munich Ins2C95S Mutant Mice

Nadja Herbach, Birgit Rathkolb, Elisabeth Kemter, Lisa Pichl, Matthias Klaften, Martin Hrabé de Angelis, Philippe A. Halban, Eckhard Wolf, Bernhard Aigner, Ruediger Wanke
Journal: Diabetes
Diabetes 2007;56(5):1268–1276
https://doi.org/10.2337/db06-0658
Published: 01 May 2007
View article titled, Dominant-Negative Effects of a Novel Mutated <em>Ins2</em> Allele Causes Early-Onset Diabetes and Severe β-Cell Loss in Munich <em>Ins2</em><sup>C95S</sup> Mutant Mice
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Journal Articles

Pro-Survival Role of Gelsolin in Mouse β-Cells

Barbara Yermen, Alejandra Tomas, Philippe A. Halban
Journal: Diabetes
Diabetes 2007;56(1):80–87
https://doi.org/10.2337/db06-0769
Published: 01 January 2007
View article titled, Pro-Survival Role of Gelsolin in Mouse β-Cells
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Journal Articles

Impaired NH2-Terminal Processing of Human Proislet Amyloid Polypeptide by the Prohormone Convertase PC2 Leads to Amyloid Formation and Cell Death

Lucy Marzban, Christopher J. Rhodes, Donald F. Steiner, Leena Haataja, Philippe A. Halban, C. Bruce Verchere
Journal: Diabetes
Diabetes 2006;55(8):2192–2201
https://doi.org/10.2337/db05-1566
Published: 01 August 2006
View article titled, Impaired NH<sub>2</sub>-Terminal Processing of Human Proislet Amyloid Polypeptide by the Prohormone Convertase PC2 Leads to Amyloid Formation and Cell Death
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Journal Articles

Blockade of β1 Integrin–Laminin-5 Interaction Affects Spreading and Insulin Secretion of Rat β-Cells Attached on Extracellular Matrix

Geraldine Parnaud, Eva Hammar, Dominique G. Rouiller, Mathieu Armanet, Philippe A. Halban, Domenico Bosco
Journal: Diabetes
Diabetes 2006;55(5):1413–1420
https://doi.org/10.2337/db05-1388
Published: 01 May 2006
View article titled, Blockade of β1 Integrin–Laminin-5 Interaction Affects Spreading and Insulin Secretion of Rat β-Cells Attached on Extracellular Matrix
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Journal Articles

Extracellular Matrix Protects Pancreatic β-Cells Against Apoptosis: Role of Short- and Long-Term Signaling Pathways

Eva Hammar, Géraldine Parnaud, Domenico Bosco, Nadja Perriraz, Kathrin Maedler, Marc Donath, Dominique G. Rouiller, Philippe A. Halban
Journal: Diabetes
Diabetes 2004;53(8):2034–2041
https://doi.org/10.2337/diabetes.53.8.2034
Published: 01 August 2004
View article titled, Extracellular Matrix Protects Pancreatic β-Cells Against Apoptosis: <subtitle>Role of Short- and Long-Term Signaling Pathways</subtitle>
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Journal Articles

Role of β-Cell Prohormone Convertase (PC)1/3 in Processing of Pro-Islet Amyloid Polypeptide

Lucy Marzban, Genny Trigo-Gonzalez, Xiaorong Zhu, Christopher J. Rhodes, Philippe A. Halban, Donald F. Steiner, C. Bruce Verchere
Journal: Diabetes
Diabetes 2004;53(1):141–148
https://doi.org/10.2337/diabetes.53.1.141
Published: 01 January 2004
View article titled, Role of β-Cell Prohormone Convertase (PC)1/3 in Processing of Pro-Islet Amyloid Polypeptide
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Journal Articles

Dominant Negative Pathogenesis by Mutant Proinsulin in the Akita Diabetic Mouse

Tetsuro Izumi, Hiromi Yokota-Hashimoto, Shengli Zhao, Jie Wang, Philippe A. Halban, Toshiyuki Takeuchi
Journal: Diabetes
Diabetes 2003;52(2):409–416
https://doi.org/10.2337/diabetes.52.2.409
Published: 01 February 2003
View article titled, Dominant Negative Pathogenesis by Mutant Proinsulin in the Akita Diabetic Mouse
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Journal Articles

Gene and Cell-Replacement Therapy in the Treatment of Type 1 Diabetes: How High Must the Standards Be Set?

Philippe A. Halban, Steven E. Kahn, Åke Lernmark, Christopher J. Rhodes
Journal: Diabetes
Diabetes 2001;50(10):2181–2191
https://doi.org/10.2337/diabetes.50.10.2181
Published: 01 October 2001
View article titled, Gene and Cell-Replacement Therapy in the Treatment of Type 1 Diabetes: <subtitle>How High Must the Standards Be Set?</subtitle>
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Journal Articles

Increased Intracellular Calcium Is Required for Spreading of Rat Islet β-Cells on Extracellular Matrix

Domenico Bosco, Carmen Gonelle-Gispert, Claes B. Wollheim, Philippe A. Halban, Dominique G. Rouiller
Journal: Diabetes
Diabetes 2001;50(5):1039–1046
https://doi.org/10.2337/diabetes.50.5.1039
Published: 01 May 2001
View article titled, Increased Intracellular Calcium Is Required for Spreading of Rat Islet β-Cells on Extracellular Matrix
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Journal Articles

Release of Incompletely Processed Proinsulin Is the Cause of the Disproportionate Proinsulinemia of NIDDM

Steven E Kahn, Philippe A Halban
Journal: Diabetes
Diabetes 1997;46(11):1725–1732
https://doi.org/10.2337/diab.46.11.1725
Published: 01 November 1997
View article titled, Release of Incompletely Processed Proinsulin Is the Cause of the Disproportionate Proinsulinemia of NIDDM
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Journal Articles

Processing of Proinsulin by Furin, PC2, and PC3 in (Co) Transfected COS (Monkey Kidney) Cells

Florence Vollenweider, Jocelyne Kaufmann, Jean-Claude Irminger, Philippe A Halban
Journal: Diabetes
Diabetes 1995;44(9):1075–1080
https://doi.org/10.2337/diab.44.9.1075
Published: 01 September 1995
View article titled, Processing of Proinsulin by Furin, PC2, and PC3 in (Co) Transfected COS (Monkey Kidney) Cells
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Journal Articles

Kinetics of Proinsulin Conversion in Human Islets

Stéphane Sizonenko, Jean-Claude Irminger, Léo Buhler, Shaoping Deng, Philippe Morel, Philippe A Halban
Journal: Diabetes
Diabetes 1993;42(6):933–936
https://doi.org/10.2337/diab.42.6.933
Published: 01 June 1993
View article titled, Kinetics of Proinsulin Conversion in Human Islets
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Journal Articles

Spontaneous Reassociation of Dispersed Adult Rat Pancreatic Islet Cells Into Aggregates With Three-Dimensional Architecture Typical of Native Islets

Philippe A Halban, Susan L Powers, Katherine L George, Susan Bonner-Weir
Journal: Diabetes
Diabetes 1987;36(7):783–790
https://doi.org/10.2337/diab.36.7.783
Published: 01 July 1987
View article titled, Spontaneous Reassociation of Dispersed Adult Rat Pancreatic Islet Cells Into Aggregates With Three-Dimensional Architecture Typical of Native Islets
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