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Journal Articles

Nicotinic Signaling Stimulates Glucagon Secretion in Mouse and Human Pancreatic α-Cells

Alexander Hamilton, Quan Zhang, Rui Gao, Thomas G. Hill, Albert Salehi, Jakob G. Knudsen, Matthew B. Draper, Paul R.V. Johnson, Patrik Rorsman, Andrei I. Tarasov
Journal: Diabetes
Diabetes 2024;74(1):53–64
https://doi.org/10.2337/db23-0809
Published: 30 October 2024
View article titled, Nicotinic Signaling Stimulates Glucagon Secretion in Mouse and Human Pancreatic α-Cells
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Meeting Abstracts

199-OR: Optogenetic Control of Pancreatic Delta Cells Reveals Their Central Role in Hormone Release from Pancreatic Islets

HAIQIANG DOU, CAROLINE A. MIRANDA, JOHAN TOLÖ, QUAN ZHANG, PATRIK RORSMAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):199-OR
https://doi.org/10.2337/db23-199-OR
Published: 20 June 2023
View article titled, 199-OR: Optogenetic Control of Pancreatic Delta Cells Reveals Their Central Role in Hormone Release from Pancreatic Islets
Journal Articles

“Take Me To Your Leader”: An Electrophysiological Appraisal of the Role of Hub Cells in Pancreatic Islets

Leslie S. Satin, Quan Zhang, Patrik Rorsman
Journal: Diabetes
Diabetes 2020;69(5):830–836
https://doi.org/10.2337/dbi19-0012
Published: 13 April 2020
View article titled, “Take Me To Your Leader”: An Electrophysiological Appraisal of the Role of Hub Cells in Pancreatic Islets
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Meeting Abstracts

339-LB: Modulation of Insulin and Glucagon Secretion by Optogenetic Control of Delta-Cell Electrical Activity in Pancreatic Islets

HAIQIANG DOU, CAROLINE A. MIRANDA, QUAN ZHANG, PATRIK RORSMAN, JOHAN TOLö
Journal: Diabetes
Diabetes 2019;68(Supplement_1):339-LB
https://doi.org/10.2337/db19-339-LB
Published: 01 June 2019
View article titled, 339-LB: Modulation of Insulin and Glucagon Secretion by Optogenetic Control of Delta-Cell Electrical Activity in Pancreatic Islets
Journal Articles

Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells

Alexander Hamilton, Quan Zhang, Albert Salehi, Mara Willems, Jakob G. Knudsen, Anna K. Ringgaard, Caroline E. Chapman, Alejandro Gonzalez-Alvarez, Nicoletta C. Surdo, Manuela Zaccolo, Davide Basco, Paul R.V. Johnson, Reshma Ramracheya, Guy A. Rutter, Antony Galione, Patrik Rorsman, Andrei I. Tarasov
Journal: Diabetes
Diabetes 2018;67(6):1128–1139
https://doi.org/10.2337/db17-1102
Published: 21 March 2018
View article titled, Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca<sup>2+</sup> Mobilization From Acidic Stores in Pancreatic α-Cells
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Includes: Supplementary data
Journal Articles

Membrane Potential-Dependent Inactivation of Voltage-Gated Ion Channels in α-Cells Inhibits Glucagon Secretion From Human Islets

Reshma Ramracheya, Caroline Ward, Makoto Shigeto, Jonathan N. Walker, Stefan Amisten, Quan Zhang, Paul R. Johnson, Patrik Rorsman, Matthias Braun
Journal: Diabetes
Diabetes 2010;59(9):2198–2208
https://doi.org/10.2337/db09-1505
Published: 14 June 2010
View article titled, Membrane Potential-Dependent Inactivation of Voltage-Gated Ion Channels in α-Cells Inhibits Glucagon Secretion From Human Islets
Open the PDF for Membrane Potential-Dependent Inactivation of Voltage-Gated Ion Channels in α-Cells Inhibits Glucagon Secretion From Human Islets in another window
Includes: Supplementary data
Journal Articles

Progression of Diet-Induced Diabetes in C57BL6J Mice Involves Functional Dissociation of Ca2+ Channels From Secretory Vesicles

Stephan C. Collins, Michael B. Hoppa, Jonathan N. Walker, Stefan Amisten, Fernando Abdulkader, Martin Bengtsson, Jane Fearnside, Reshma Ramracheya, Ayo A. Toye, Quan Zhang, Anne Clark, Dominique Gauguier, Patrik Rorsman
Journal: Diabetes
Diabetes 2010;59(5):1192–1201
https://doi.org/10.2337/db09-0791
Published: 11 February 2010
View article titled, Progression of Diet-Induced Diabetes in C57BL6J Mice Involves Functional Dissociation of Ca<sup>2+</sup> Channels From Secretory Vesicles
Open the PDF for Progression of Diet-Induced Diabetes in C57BL6J Mice Involves Functional Dissociation of Ca<sup>2+</sup> Channels From Secretory Vesicles in another window
Includes: Supplementary data
Journal Articles

Voltage-Gated Ion Channels in Human Pancreatic β-Cells: Electrophysiological Characterization and Role in Insulin Secretion

Matthias Braun, Reshma Ramracheya, Martin Bengtsson, Quan Zhang, Jovita Karanauskaite, Chris Partridge, Paul R. Johnson, Patrik Rorsman
Journal: Diabetes
Diabetes 2008;57(6):1618–1628
https://doi.org/10.2337/db07-0991
Published: 01 June 2008
View article titled, Voltage-Gated Ion Channels in Human Pancreatic β-Cells: Electrophysiological Characterization and Role in Insulin Secretion
Open the PDF for Voltage-Gated Ion Channels in Human Pancreatic β-Cells: Electrophysiological Characterization and Role in Insulin Secretion in another window
Includes: Supplementary data