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Journal Articles

Strong Association of Autoantibodies Targeting Deamidated Extracellular Epitopes of Insulinoma Antigen-2 With Clinical Onset of Type 1 Diabetes

Xiaofan Jia, Janet M. Wenzlau, Caiguo Zhang, Fran Dong, Kathleen Waugh, R. David Leslie, Marian J. Rewers, Aaron W. Michels, Liping Yu, Diabetes Autoimmunity Study in the Young (DAISY) and Autoimmunity Screening for Kids (ASK) Study Group and the Action LADA Consortium
Journal: Diabetes
Diabetes 2025;74(4):544–553
https://doi.org/10.2337/db24-0571
Published: 16 January 2025
View article titled, Strong Association of Autoantibodies Targeting Deamidated Extracellular Epitopes of Insulinoma Antigen-2 With Clinical Onset of Type 1 Diabetes
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Journal Articles

Diabetes: Concepts of β-Cell Organ Dysfunction and Failure Would Lead to Earlier Diagnoses and Prevention

M. Arthur Charles, R. David Leslie
Journal: Diabetes
Diabetes 2021;70(11):2444–2456
https://doi.org/10.2337/dbi21-0012
Published: 22 October 2021
View article titled, Diabetes: Concepts of β-Cell Organ Dysfunction and Failure Would Lead to Earlier Diagnoses and Prevention
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Journal Articles

Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study

Alexia Cardona, Felix R. Day, John R.B. Perry, Marie Loh, Audrey Y. Chu, Benjamin Lehne, Dirk S. Paul, Luca A. Lotta, Isobel D. Stewart, Nicola D. Kerrison, Robert A. Scott, Kay-Tee Khaw, Nita G. Forouhi, Claudia Langenberg, Chunyu Liu, Michael M. Mendelson, Daniel Levy, Stephan Beck, R. David Leslie, Josée Dupuis, James B. Meigs, Jaspal S. Kooner, Jussi Pihlajamäki, Allan Vaag, Alexander Perfilyev, Charlotte Ling, Marie-France Hivert, John C. Chambers, Nicholas J. Wareham, Ken K. Ong
Journal: Diabetes
Diabetes 2019;68(12):2315–2326
https://doi.org/10.2337/db18-0290
Published: 10 September 2019
View article titled, Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study
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Includes: Supplementary data
Journal Articles

Frequency, Immunogenetics, and Clinical Characteristics of Latent Autoimmune Diabetes in China (LADA China Study): A Nationwide, Multicenter, Clinic-Based Cross-Sectional Study

Zhiguang Zhou, Yufei Xiang, Linong Ji, Weiping Jia, Guang Ning, Gan Huang, Lin Yang, Jian Lin, Zhenqi Liu, William A. Hagopian, R. David Leslie, on behalf of the LADA China Study Group
Journal: Diabetes
Diabetes 2013;62(2):543–550
https://doi.org/10.2337/db12-0207
Published: 17 January 2013
View article titled, Frequency, Immunogenetics, and Clinical Characteristics of Latent Autoimmune Diabetes in China (LADA China Study): <subtitle>A Nationwide, Multicenter, Clinic-Based Cross-Sectional Study</subtitle>
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Journal Articles

Glycotoxin and Autoantibodies Are Additive Environmentally Determined Predictors of Type 1 Diabetes: A Twin and Population Study

Huriya Beyan, Harriette Riese, Mohammed I. Hawa, Guisi Beretta, Howard W. Davidson, John C. Hutton, Huibert Burger, Michael Schlosser, Harold Snieder, Bernhard O. Boehm, R. David Leslie
Journal: Diabetes
Diabetes 2012;61(5):1192–1198
https://doi.org/10.2337/db11-0971
Published: 13 April 2012
View article titled, Glycotoxin and Autoantibodies Are Additive Environmentally Determined Predictors of Type 1 Diabetes: <subtitle>A Twin and Population Study</subtitle>
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Journal Articles

Metabolomics Makes a Mark: Early Changes Associated With Autoimmune Diabetes

R. David Leslie, Huriya Beyan
Journal: Diabetes
Diabetes 2011;60(11):2688–2690
https://doi.org/10.2337/db11-1177
Published: 17 October 2011
View article titled, Metabolomics Makes a Mark: Early Changes Associated With Autoimmune Diabetes
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Journal Articles

Predicting Adult-Onset Autoimmune Diabetes: Clarity From Complexity

R. David Leslie
Journal: Diabetes
Diabetes 2010;59(2):330–331
https://doi.org/10.2337/db09-1620
Published: 01 February 2010
View article titled, Predicting Adult-Onset Autoimmune Diabetes: <subtitle>Clarity From Complexity</subtitle>
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Journal Articles

Distinct Monocyte Gene-Expression Profiles in Autoimmune Diabetes

Roos C. Padmos, Nanette C. Schloot, Huriya Beyan, Cindy Ruwhof, Frank J.T. Staal, Dick de Ridder, Henk-Jan Aanstoot, Wai Kwan Lam-Tse, Harm de Wit, Christian de Herder, Roos C. Drexhage, Barbara Menart, R. David Leslie, Hemmo A. Drexhage, the LADA Consortium
Journal: Diabetes
Diabetes 2008;57(10):2768–2773
https://doi.org/10.2337/db08-0496
Published: 01 October 2008
View article titled, Distinct Monocyte Gene-Expression Profiles in Autoimmune Diabetes
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Includes: Supplementary data
Journal Articles

Early Environmental Events as a Cause of IDDM: Evidence and Implications

R David Leslie, Robert B Elliott
Journal: Diabetes
Diabetes 1994;43(7):843–850
https://doi.org/10.2337/diab.43.7.843
Published: 01 July 1994
View article titled, Early Environmental Events as a Cause of IDDM: Evidence and Implications
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Journal Articles

Decreased Growth Velocity Before IDDM Onset

R David Leslie, Simon Lo, B Anne Millward, John Honour, David A Pyke
Journal: Diabetes
Diabetes 1991;40(2):211–216
https://doi.org/10.2337/diab.40.2.211
Published: 01 February 1991
View article titled, Decreased Growth Velocity Before IDDM Onset
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