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Ralph A. DeFronzo
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Meeting Abstracts

68-LB: Early Pharmacological Intervention (EPIC) to Preserve Beta-Cell Function in Prediabetes (PreDM)

ALBERTO CHAVEZ, AURORA MEROVCI, SIVARAM NEPPALA, LUIS A. CRUZ MORENO, GOZDE BASKOY, FRANCISCA M. ACOSTA, ANDREA A. HANSIS-DIARTE, CURTISS L. PUCKETT, JR., JOHN M. ADAMS, III, MUHAMMAD ABDUL-GHANI, CURTIS L. TRIPLITT, EUGENIO CERSOSIMO, RALPH A. DEFRONZO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):68-LB
https://doi.org/10.2337/db23-68-LB
Published: 20 June 2023
View article titled, 68-LB: Early Pharmacological Intervention (EPIC) to Preserve Beta-Cell Function in Prediabetes (PreDM)
Meeting Abstracts

887-P: Renal Benefit of Dapagliflozin Therapy in Hyperfiltering Type 2 Diabetes Patients

GOZDE BASKOY, YUEJUAN QIN, EUGENIO CERSOSIMO, CAROLINA SOLIS-HERRERA, JOHN M. ADAMS, III, RALPH A. DEFRONZO, CURTIS L. TRIPLITT
Journal: Diabetes
Diabetes 2023;72(Supplement_1):887-P
https://doi.org/10.2337/db23-887-P
Published: 20 June 2023
View article titled, 887-P: Renal Benefit of Dapagliflozin Therapy in Hyperfiltering Type 2 Diabetes Patients
Meeting Abstracts

124-OR: Effects of Dapagliflozin Therapy on Renal Hemodynamics in Type 2 Diabetes Patients

YUEJUAN QIN, GOZDE BASKOY, CURTIS L. TRIPLITT, CAROLINA SOLIS-HERRERA, JOHN M. ADAMS__III, RALPH A. DEFRONZO, EUGENIO CERSOSIMO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):124-OR
https://doi.org/10.2337/db23-124-OR
Published: 20 June 2023
View article titled, 124-OR: Effects of Dapagliflozin Therapy on Renal Hemodynamics in Type 2 Diabetes Patients
Meeting Abstracts

99-LB: Myocardial Blood Flow in Association with Baseline Ejection Fraction after Elevation in Plasma Ketones in Patients with T2DM and Heart Failure

CAROLINA SOLIS-HERRERA, YUEJUAN QIN, HENRI HONKA, FRANCISCA M. ACOSTA, ALEXANDER MOODY, ALBERTO CHAVEZ, CURTIS L. TRIPLITT, GEOFFREY D. CLARKE, EUGENIO CERSOSIMO, RALPH A. DEFRONZO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):99-LB
https://doi.org/10.2337/db23-99-LB
Published: 20 June 2023
View article titled, 99-LB: Myocardial Blood Flow in Association with Baseline Ejection Fraction after Elevation in Plasma Ketones in Patients with T2DM and Heart Failure
Meeting Abstracts

853-P: Effect of Ketogenic Diet with Weight Maintenance in Type 2 Diabetes (T2D)

AURORA MEROVCI, BRITTANY FINLEY, ALBERTO CHAVEZ, ANDREA A. HANSIS-DIARTE, SIVARAM NEPPALA, DEVJIT TRIPATHY, RALPH A. DEFRONZO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):853-P
https://doi.org/10.2337/db23-853-P
Published: 20 June 2023
View article titled, 853-P: Effect of Ketogenic Diet with Weight Maintenance in Type 2 Diabetes (T2D)
Meeting Abstracts

869-P: Effect of Dapagliflozin on Renal Oxygen Delivery and Consumption in T2DM and NGT Subjects

DEVJIT TRIPATHY, XI CHEN, ROBERT CHILTON, ANDREA A. HANSIS-DIARTE, MARZIEH SALEHI, CAROLINA SOLIS-HERRERA, EUGENIO CERSOSIMO, RALPH A. DEFRONZO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):869-P
https://doi.org/10.2337/db23-869-P
Published: 20 June 2023
View article titled, 869-P: Effect of Dapagliflozin on Renal Oxygen Delivery and Consumption in T2DM and NGT Subjects
Meeting Abstracts

98-LB: Effects of SGLT2 Inhibition on Skeletal Muscle Bioenergetics and Myocellular Lipids in Patients with T2D and HFrEF

YUEJUAN QIN, NOAH D. SANCHEZ, ALEXANDER MOODY, FRANCISCA M. ACOSTA, SIVARAM NEPPALA, MARISSA BROWN, HENRI HONKA, LUIS A. CRUZ MORENO, CURTIS L. TRIPLITT, GEOFFREY D. CLARKE, EUGENIO CERSOSIMO, RALPH A. DEFRONZO, CAROLINA SOLIS-HERRERA
Journal: Diabetes
Diabetes 2023;72(Supplement_1):98-LB
https://doi.org/10.2337/db23-98-LB
Published: 20 June 2023
View article titled, 98-LB: Effects of SGLT2 Inhibition on Skeletal Muscle Bioenergetics and Myocellular Lipids in Patients with T2D and HFrEF
Meeting Abstracts

97-LB: Empagliflozin Improves Cardiopulmonary Function and VE/VCO2 in Patients with T2D and HFrEF

YUEJUAN QIN, FRANCISCA M. ACOSTA, SIVARAM NEPPALA, TIFFANY M. CORTES, ALLISON STEPANENKO, ALEXANDER MOODY, NOAH D. SANCHEZ, MARISSA BROWN, LUIS A. CRUZ MORENO, CURTIS L. TRIPLITT, GEOFFREY D. CLARKE, EUGENIO CERSOSIMO, SARA E. ESPINOZA, RALPH A. DEFRONZO, CAROLINA SOLIS-HERRERA
Journal: Diabetes
Diabetes 2023;72(Supplement_1):97-LB
https://doi.org/10.2337/db23-97-LB
Published: 20 June 2023
View article titled, 97-LB: Empagliflozin Improves Cardiopulmonary Function and VE/VCO2 in Patients with T2D and HFrEF
Meeting Abstracts

360-OR: Hyperglucagonemia Reduces De Novo Lipogenesis and Increases Gluconeogenesis in Healthy Subjects

XI CHEN, FABRIZIA CARLI, SAMANTHA PEZZICA, GABRIELE MOCCIARO, DEMETRIO CIOCIARO, AMALIA GASTALDELLI, RALPH A. DEFRONZO, DEVJIT TRIPATHY
Journal: Diabetes
Diabetes 2022;71(Supplement_1):360-OR
https://doi.org/10.2337/db22-360-OR
Published: 01 June 2022
View article titled, 360-OR: Hyperglucagonemia Reduces De Novo Lipogenesis and Increases Gluconeogenesis in Healthy Subjects
Meeting Abstracts

1326-P: Baseline OGTT as a Predictor of Type 2 Diabetes Progression in the GRADE Study

KRISTINA UTZSCHNEIDER, NAJI YOUNES, NICOLE M. BUTERA, ASHOK BALASUBRAMANYAM, CYRUS DESOUZA, JONATHAN KRAKOFF, JOSHUA I. BARZILAY, RALPH A. DEFRONZO, RICHARD M. BERGENSTAL, TOM A. ELASY, WILLY VALENCIA, CHARLES MA, NEDA RASOULI, STEVEN E. KAHN, WILLIAM SIVITZ, GRADE RESEARCH GROUP
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1326-P
https://doi.org/10.2337/db22-1326-P
Published: 01 June 2022
View article titled, 1326-P: Baseline OGTT as a Predictor of Type 2 Diabetes Progression in the GRADE Study
Meeting Abstracts

55-LB: Effect of Dapagliflozin on Renal and Hepatic Glucose Kinetics in T2DM and NGT Subjects

XI CHEN, CAROLINA SOLIS-HERRERA, DEVJIT TRIPATHY, ANDREA A. HANSIS-DIARTE, ROBERT CHILTON, EUGENIO CERSOSIMO, RALPH A. DEFRONZO
Journal: Diabetes
Diabetes 2022;71(Supplement_1):55-LB
https://doi.org/10.2337/db22-55-LB
Published: 01 June 2022
View article titled, 55-LB: Effect of Dapagliflozin on Renal and Hepatic Glucose Kinetics in T2DM and NGT Subjects
Meeting Abstracts

175-OR: Effect of Hyperketonemia on Cardiac Efficiency in Patients with Heart Failure and Type 2 Diabetes

CAROLINA SOLIS-HERRERA, YUEJUAN QIN, HENRI HONKA, ALEXANDER MOODY, GEOFFREY D. CLARKE, CURTIS L. TRIPLITT, EUGENIO CERSOSIMO, RALPH A. DEFRONZO
Journal: Diabetes
Diabetes 2022;71(Supplement_1):175-OR
https://doi.org/10.2337/db22-175-OR
Published: 01 June 2022
View article titled, 175-OR: Effect of Hyperketonemia on Cardiac Efficiency in Patients with Heart Failure and Type 2 Diabetes
Meeting Abstracts

1324-P: Short-Term Effects of Glycemia-Lowering Medications on ß-Cell Function in the GRADE Study

NEDA RASOULI, JEANINE ALBU, ROBERT M. COHEN, RALPH A. DEFRONZO, ELSA DIAZ, ALOKANANDA GHOSH, JOSE A. LUCHSINGER, JANET B. MCGILL, LAURE SAYYED KASSEM, WILLIAM SIVITZ, WILLIAM V. TAMBORLANE, KRISTINA UTZSCHNEIDER, NAJI YOUNES, STEVEN E. KAHN, GRADE RESEARCH GROUP
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1324-P
https://doi.org/10.2337/db22-1324-P
Published: 01 June 2022
View article titled, 1324-P: Short-Term Effects of Glycemia-Lowering Medications on ß-Cell Function in the GRADE Study
Meeting Abstracts

54-LB: Distinct Mechanisms Are Responsible for the Increase in Endogenous Glucose Production and Ketone Formation following Empagliflozin in T2DM Patients

SIHAM ABDELGANI, JOHN M. ADAMS, III, GIUSEPPE DANIELE, FAHD ALMULLA, RALPH A. DEFRONZO, MUHAMMAD ABDUL-GHANI, MOHAMED ABU-FARHA, STEFANO DEL PRATO
Journal: Diabetes
Diabetes 2022;71(Supplement_1):54-LB
https://doi.org/10.2337/db22-54-LB
Published: 01 June 2022
View article titled, 54-LB: Distinct Mechanisms Are Responsible for the Increase in Endogenous Glucose Production and Ketone Formation following Empagliflozin in T2DM Patients
Meeting Abstracts

644-P: Effect of PharmacologIC (EPIC) Therapy on Insulin Sensitivity and Beta-Cell Function in Prediabetes (PreDM)

ALBERTO O. CHAVEZ VELAZQUEZ, EMAD ALI, AURORA MEROVCI, CHRISTINA AGYIN, IV, TOMOKO TERASAWA, MUHAMMAD ABDUL-GHANI, CURTIS L. TRIPLITT, EUGENIO CERSOSIMO, RALPH A. DEFRONZO
Journal: Diabetes
Diabetes 2022;71(Supplement_1):644-P
https://doi.org/10.2337/db22-644-P
Published: 01 June 2022
View article titled, 644-P: Effect of PharmacologIC (EPIC) Therapy on Insulin Sensitivity and Beta-Cell Function in Prediabetes (PreDM)
Meeting Abstracts

857-P: Mechanisms of Dapagliflozin to Reduce Intraglomerular Pressure in Patients with Type 2 Diabetes

MARYAM BARKHORDARIAN, CURTIS L. TRIPLITT, CAROLINA SOLIS-HERRERA, JOHN M. ADAMS, III, RALPH A. DEFRONZO, EUGENIO CERSOSIMO
Journal: Diabetes
Diabetes 2022;71(Supplement_1):857-P
https://doi.org/10.2337/db22-857-P
Published: 01 June 2022
View article titled, 857-P: Mechanisms of Dapagliflozin to Reduce Intraglomerular Pressure in Patients with Type 2 Diabetes
Meeting Abstracts

211-OR: Plasma Insulin Is Required for the Increase in Plasma ANGPTL8 Concentration following Glucose Ingestion

MOHAMED ABU-FARHA, JEHAD ABUBAKER, IRINA AL KHAIRI, PREETHI T. CHERIAN, CHRISTINA AGYIN, IV, SIHAM ABDELGANI, EBAA S. ALOZAIRI, JOHN M. ADAMS, II, FAHD ALMULLA, RALPH A. DEFRONZO, MUHAMMAD ABDUL-GHANI
Journal: Diabetes
Diabetes 2022;71(Supplement_1):211-OR
https://doi.org/10.2337/db22-211-OR
Published: 01 June 2022
View article titled, 211-OR: Plasma Insulin Is Required for the Increase in Plasma ANGPTL8 Concentration following Glucose Ingestion
Meeting Abstracts

1298-P: Metabolic Clearance of Insulin Is Altered after Gastric Bypass and Sleeve Gastrectomy

MARIA S. RAYAS, RALPH A. DEFRONZO, AMALIA GASTALDELLI, MARZIEH SALEHI
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1298-P
https://doi.org/10.2337/db22-1298-P
Published: 01 June 2022
View article titled, 1298-P: Metabolic Clearance of Insulin Is Altered after Gastric Bypass and Sleeve Gastrectomy
Meeting Abstracts

215-LB: The Role of GLP-1 in Glycemic Response to Protein Ingestion after Gastric Bypass Surgery or Sleeve Gastrectomy

MARIA S. RAYAS, HENRI HONKA, RALPH A. DEFRONZO, AMALIA GASTALDELLI, MARZIEH SALEHI
Journal: Diabetes
Diabetes 2021;70(Supplement_1):215-LB
https://doi.org/10.2337/db21-215-LB
Published: 01 June 2021
View article titled, 215-LB: The Role of GLP-1 in Glycemic Response to Protein Ingestion after Gastric Bypass Surgery or Sleeve Gastrectomy
Meeting Abstracts

257-OR: Short-Term Hyperglucagonemia Induces Adipose Tissue Insulin Resistance and Inflammation In Vivo

XI CHEN, MARCEL FOURCAUDOT, LUKE NORTON, RALPH A. DEFRONZO, DEVJIT TRIPATHY
Journal: Diabetes
Diabetes 2021;70(Supplement_1):257-OR
https://doi.org/10.2337/db21-257-OR
Published: 01 June 2021
View article titled, 257-OR: Short-Term Hyperglucagonemia Induces Adipose Tissue Insulin Resistance and Inflammation In Vivo