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Meeting Abstracts

1555-P: Novel Imaging Platform Highlights the Disconnect between ß-Cell Mass and Glucose Control in the Onset of Type 1 Diabetes

CORENTIN CRAS-MÉNEUR, RANDY J. SEELEY, PETER ARVAN

Diabetes 2023;72(Supplement_1):1555-P

https://doi.org/10.2337/db23-1555-P

Published: 20 June 2023

View article titled, 1555-P: Novel Imaging Platform Highlights the Disconnect between ß-Cell Mass and Glucose Control in the Onset of Type 1 Diabetes

Journal Articles

GDF15 Mediates the Effect of Skeletal Muscle Contraction on Glucose-Stimulated Insulin Secretion

Hui Zhang, Anny Mulya, Stephan Nieuwoudt, Bolormaa Vandanmagsar, Ruth McDowell, Elizabeth C. Heintz, Elizabeth R.M. Zunica, J. Jason Collier, Nadejda Bozadjieva-Kramer, Randy J. Seeley, Christopher L. Axelrod, John P. Kirwan

Diabetes 2023;72(8):1070–1082

https://doi.org/10.2337/db22-0019

Published: 24 May 2023

View article titled, GDF15 Mediates the Effect of Skeletal Muscle Contraction on Glucose-Stimulated Insulin Secretion

Meeting Abstracts

210-OR: Activation of GFRAL Neurons Decreases Food Intake via Aversive Pathways

PAUL V. SABATINI, RANDY J. SEELEY

Diabetes 2020;69(Supplement_1):210-OR

https://doi.org/10.2337/db20-210-OR

Published: 01 June 2020

View article titled, 210-OR: Activation of GFRAL Neurons Decreases Food Intake via Aversive Pathways

Meeting Abstracts

196-LB: Synergetic and Distinct Roles in the Control of Food Intake and Energy Balance for Subpopulations of NTS Neurons

WENWEN C. CHENG, ERMELINDA NDOKA, BASMA MAERZ, KAREN J. ROELOFS, CHRISTOPHER J. RHODES, RANDY J. SEELEY, DARLEEN A. SANDOVAL, DAVID OLSON, MARTIN G. MYERS, JR.

Diabetes 2020;69(Supplement_1):196-LB

https://doi.org/10.2337/db20-196-LB

Published: 01 June 2020

View article titled, 196-LB: Synergetic and Distinct Roles in the Control of Food Intake and Energy Balance for Subpopulations of NTS Neurons

Meeting Abstracts

2315-PUB: High Serum Ferritin Predicts Inferior Diabetes-Related Outcomes after Gastric Bypass but Not Sleeve Gastrectomy Bariatric Surgery

JENNY TONG, RAFAEL ALVAREZ, GREGORY B. RUSSELL, ALEXANDER N. KHOURI, RANDY J. SEELEY, DONALD A. MCCLAIN

Diabetes 2020;69(Supplement_1):2315-PUB

https://doi.org/10.2337/db20-2315-PUB

Published: 01 June 2020

View article titled, 2315-PUB: High Serum Ferritin Predicts Inferior Diabetes-Related Outcomes after Gastric Bypass but Not Sleeve Gastrectomy Bariatric Surgery

Journal Articles

The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1

Diabetes 2019;68(12):2223–2234

https://doi.org/10.2337/db19-0049

Published: 02 October 2019

View article titled, The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1

Includes: Supplementary data

Meeting Abstracts

2165-P: In Vivo Islet Imaging Reveals that GLP-1 Paradoxically Increases Insulin Content

CORENTIN M.H. CRAS-MÉNEUR, HENRIETTE FRIKKE-SCHMIDT, PETER ARVAN, RANDY J. SEELEY

Diabetes 2019;68(Supplement_1):2165-P

https://doi.org/10.2337/db19-2165-P

Published: 01 June 2019

View article titled, 2165-P: In Vivo Islet Imaging Reveals that GLP-1 Paradoxically Increases Insulin Content

Journal Articles

Targeting FXR and FGF19 to Treat Metabolic Diseases—Lessons Learned From Bariatric Surgery

Nadejda Bozadjieva, Kristy M. Heppner, Randy J. Seeley

Diabetes 2018;67(9):1720–1728

https://doi.org/10.2337/dbi17-0007

Published: 15 August 2018

View article titled, Targeting FXR and FGF19 to Treat Metabolic Diseases—Lessons Learned From Bariatric Surgery

Meeting Abstracts

GLP-1 Controls Pancreatic Endocrine Development

CORENTIN M.H. CRAS-MÉNEUR, RANDY J. SEELEY

Diabetes 2018;67(Supplement_1):2130-P

https://doi.org/10.2337/db18-2130-P

Published: 01 July 2018

View article titled, GLP-1 Controls Pancreatic Endocrine Development

Journal Articles

Liraglutide Modulates Appetite and Body Weight Through Glucagon-Like Peptide 1 Receptor–Expressing Glutamatergic Neurons

Jessica M. Adams, Hongjuan Pei, Darleen A. Sandoval, Randy J. Seeley, Rui B. Chang, Stephen D. Liberles, David P. Olson

Diabetes 2018;67(8):1538–1548

https://doi.org/10.2337/db17-1385

Published: 18 May 2018

View article titled, Liraglutide Modulates Appetite and Body Weight Through Glucagon-Like Peptide 1 Receptor–Expressing Glutamatergic Neurons

Includes: Supplementary data

Journal Articles

The Hypothalamic Glucagon-Like Peptide 1 Receptor Is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice

Melissa A. Burmeister, Jennifer E. Ayala, Hannah Smouse, Adriana Landivar-Rocha, Jacob D. Brown, Daniel J. Drucker, Doris A. Stoffers, Darleen A. Sandoval, Randy J. Seeley, Julio E. Ayala

Diabetes 2017;66(2):372–384

https://doi.org/10.2337/db16-1102

Published: 01 December 2016

View article titled, The Hypothalamic Glucagon-Like Peptide 1 Receptor Is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice

Includes: Supplementary data

Journal Articles

Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight

Stephanie R. Sisley, Deanna M. Arble, Adam P. Chambers, Ruth Gutierrez-Aguilar, Yanlin He, Yong Xu, David Gardner, David D. Moore, Randy J. Seeley, Darleen A. Sandoval

Diabetes 2016;65(9):2732–2741

https://doi.org/10.2337/db16-0309

Published: 23 May 2016

View article titled, Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight

Includes: Supplementary data

Journal Articles

Biologic Responses to Weight Loss and Weight Regain: Report From an American Diabetes Association Research Symposium

Rudolph L. Leibel, Randy J. Seeley, Tamara Darsow, Erika Gebel Berg, Steven R. Smith, Robert Ratner

Diabetes 2015;64(7):2299–2309

https://doi.org/10.2337/db15-0004

Published: 17 June 2015

View article titled, Biologic Responses to Weight Loss and Weight Regain: Report From an American Diabetes Association Research Symposium

Journal Articles

Insulin Detemir Is Transported From Blood to Cerebrospinal Fluid and Has Prolonged Central Anorectic Action Relative to NPH Insulin

Denovan P. Begg, Aaron A. May, Joram D. Mul, Min Liu, David A. D’Alessio, Randy J. Seeley, Stephen C. Woods

Diabetes 2015;64(7):2457–2466

https://doi.org/10.2337/db14-1364

Published: 09 February 2015

View article titled, Insulin Detemir Is Transported From Blood to Cerebrospinal Fluid and Has Prolonged Central Anorectic Action Relative to NPH Insulin

Journal Articles

Effect of Guanylate Cyclase-C Activity on Energy and Glucose Homeostasis

Denovan P. Begg, Kris A. Steinbrecher, Joram D. Mul, Adam P. Chambers, Rohit Kohli, April Haller, Mitchell B. Cohen, Stephen C. Woods, Randy J. Seeley

Diabetes 2014;63(11):3798–3804

https://doi.org/10.2337/db14-0160

Published: 13 October 2014

View article titled, Effect of Guanylate Cyclase-C Activity on Energy and Glucose Homeostasis

Journal Articles

Vertical Sleeve Gastrectomy Restores Glucose Homeostasis in Apolipoprotein A-IV KO Mice

Josh W. Pressler, April Haller, Joyce Sorrell, Fei Wang, Randy J. Seeley, Patrick Tso, Darleen A. Sandoval

Diabetes 2015;64(2):498–507

https://doi.org/10.2337/db14-0825

Published: 25 August 2014

View article titled, Vertical Sleeve Gastrectomy Restores Glucose Homeostasis in Apolipoprotein A-IV KO Mice

Journal Articles

GLP-1R Responsiveness Predicts Individual Gastric Bypass Efficacy on Glucose Tolerance in Rats

Kirk M. Habegger, Kristy M. Heppner, Sarah E. Amburgy, Nickki Ottaway, Jenna Holland, Christine Raver, Erin Bartley, Timo D. Müller, Paul T. Pfluger, Jose Berger, Mouhamadoul Toure, Stephen C. Benoit, Richard D. DiMarchi, Diego Perez-Tilve, David A. D’Alessio, Randy J. Seeley, Matthias H. Tschöp

Diabetes 2014;63(2):505–513

https://doi.org/10.2337/db13-0511

Published: 16 January 2014

View article titled, GLP-1R Responsiveness Predicts Individual Gastric Bypass Efficacy on Glucose Tolerance in Rats

Includes: Supplementary data

Journal Articles

GLP-1R Agonism Enhances Adjustable Gastric Banding in Diet-Induced Obese Rats

Kirk M. Habegger, Henriette Kirchner, Chun-Xia Yi, Kristy M. Heppner, Dan Sweeney, Nickki Ottaway, Jenna Holland, Sarah Amburgy, Christine Raver, Radhakrishna Krishna, Timo D. Müller, Diego Perez-Tilve, Paul T. Pfluger, Silvana Obici, Richard D. DiMarchi, David A. D’Alessio, Randy J. Seeley, Matthias H. Tschöp

Diabetes 2013;62(9):3261–3267

https://doi.org/10.2337/db13-0117

Published: 15 August 2013

View article titled, GLP-1R Agonism Enhances Adjustable Gastric Banding in Diet-Induced Obese Rats

Journal Articles

Vertical Sleeve Gastrectomy Is Effective in Two Genetic Mouse Models of Glucagon-Like Peptide 1 Receptor Deficiency

Hilary E. Wilson-Pérez, Adam P. Chambers, Karen K. Ryan, Bailing Li, Darleen A. Sandoval, Doris Stoffers, Daniel J. Drucker, Diego Pérez-Tilve, Randy J. Seeley

Diabetes 2013;62(7):2380–2385

https://doi.org/10.2337/db12-1498

Published: 14 June 2013

View article titled, Vertical Sleeve Gastrectomy Is Effective in Two Genetic Mouse Models of Glucagon-Like Peptide 1 Receptor Deficiency

Includes: Supplementary data

Journal Articles

Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions

Diabetes 2013;62(5):1453–1463

https://doi.org/10.2337/db12-1116

Published: 16 April 2013

View article titled, Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions

Includes: Supplementary data

NARROW

1555-P: Novel Imaging Platform Highlights the Disconnect between ß-Cell Mass and Glucose Control in the Onset of Type 1 Diabetes

GDF15 Mediates the Effect of Skeletal Muscle Contraction on Glucose-Stimulated Insulin Secretion

210-OR: Activation of GFRAL Neurons Decreases Food Intake via Aversive Pathways

196-LB: Synergetic and Distinct Roles in the Control of Food Intake and Energy Balance for Subpopulations of NTS Neurons

2315-PUB: High Serum Ferritin Predicts Inferior Diabetes-Related Outcomes after Gastric Bypass but Not Sleeve Gastrectomy Bariatric Surgery

The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1

2165-P: In Vivo Islet Imaging Reveals that GLP-1 Paradoxically Increases Insulin Content

Targeting FXR and FGF19 to Treat Metabolic Diseases—Lessons Learned From Bariatric Surgery

GLP-1 Controls Pancreatic Endocrine Development

Liraglutide Modulates Appetite and Body Weight Through Glucagon-Like Peptide 1 Receptor–Expressing Glutamatergic Neurons

The Hypothalamic Glucagon-Like Peptide 1 Receptor Is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice

Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight

Biologic Responses to Weight Loss and Weight Regain: Report From an American Diabetes Association Research Symposium

Insulin Detemir Is Transported From Blood to Cerebrospinal Fluid and Has Prolonged Central Anorectic Action Relative to NPH Insulin

Effect of Guanylate Cyclase-C Activity on Energy and Glucose Homeostasis

Vertical Sleeve Gastrectomy Restores Glucose Homeostasis in Apolipoprotein A-IV KO Mice

GLP-1R Responsiveness Predicts Individual Gastric Bypass Efficacy on Glucose Tolerance in Rats

GLP-1R Agonism Enhances Adjustable Gastric Banding in Diet-Induced Obese Rats

Vertical Sleeve Gastrectomy Is Effective in Two Genetic Mouse Models of Glucagon-Like Peptide 1 Receptor Deficiency

Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions

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