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Richard DiMarchi
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Meeting Abstracts

1559-P: Glucagon Receptor–Mediated Improvements in Glycemia Are Dependent on Agonist Pharmacodynamics

SHELLY NASON, TEAYOUN KIM, JESSICA ANTIPENKO, BIN YANG, RICHARD DIMARCHI, KIRK M. HABEGGER
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1559-P
https://doi.org/10.2337/db23-1559-P
Published: 20 June 2023
View article titled, 1559-P: Glucagon Receptor–Mediated Improvements in Glycemia Are Dependent on Agonist Pharmacodynamics
Journal Articles

Hepatic mTORC2 Signaling Facilitates Acute Glucagon Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice

Teayoun Kim, Shelly Nason, Jessica Antipenko, Brian Finan, Anath Shalev, Richard DiMarchi, Kirk M. Habegger
Journal: Diabetes
Diabetes 2022;71(10):2123–2135
https://doi.org/10.2337/db21-1018
Published: 25 July 2022
View article titled, Hepatic mTORC2 Signaling Facilitates Acute Glucagon Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice
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Meeting Abstracts

197-OR: Glucagon Receptor Agonism Stimulates Time-Dependent Glycemic Regulation

SHELLY NASON, TEAYOUN KIM, JESSICA P. ANTIPENKO, BRIAN FINAN, RICHARD DIMARCHI, KIRK M. HABEGGER
Journal: Diabetes
Diabetes 2022;71(Supplement_1):197-OR
https://doi.org/10.2337/db22-197-OR
Published: 01 June 2022
View article titled, 197-OR: Glucagon Receptor Agonism Stimulates Time-Dependent Glycemic Regulation
Meeting Abstracts

230-OR: Hepatic TORC2 Signaling Facilitates Glucagon-Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice

TEAYOUN KIM, SHELLY NASON, JESSICA P. ANTIPENKO, BRIAN FINAN, ANATH SHALEV, RICHARD DIMARCHI, KIRK M. HABEGGER
Journal: Diabetes
Diabetes 2022;71(Supplement_1):230-OR
https://doi.org/10.2337/db22-230-OR
Published: 01 June 2022
View article titled, 230-OR: Hepatic TORC2 Signaling Facilitates Glucagon-Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice
Meeting Abstracts

336-OR: Mandarin Fish Ranavirus Viral Insulin/IGF-Like Peptide Inhibits Human IGF-1 Receptor

MARTINA CHRUDINOVA, VASILY GELFANOV, LENKA ZAKOVA, JULIANNE CUTONE, AMAYA POWIS, KAAN SEVGI, JIRI JIRACEK, RICHARD DIMARCHI, EMRAH ALTINDIS
Journal: Diabetes
Diabetes 2021;70(Supplement_1):336-OR
https://doi.org/10.2337/db21-336-OR
Published: 01 June 2021
View article titled, 336-OR: Mandarin Fish Ranavirus Viral Insulin/IGF-Like Peptide Inhibits Human IGF-1 Receptor
Meeting Abstracts

936-P: Plasma Proteomic Profiling Delineates Treatment Efficacy of a GLP-1/GIP Coagonist in Female and Male Mice

SUSANNA M. HOFMANN, NICOLAI J. WEWER ALBRECHTSEN, MATTHIAS H. TSCHÖP, ANNETTE FEUCHTINGER, MARKUS BRIELMEIER, BRIAN FINAN, RICHARD DIMARCHI, MAXIMILIAN KLEINERT, STEPHAN SACHS, TIMO D. MÜLLER, KERSTIN STEMMER, MATTHIAS MANN
Journal: Diabetes
Diabetes 2020;69(Supplement_1):936-P
https://doi.org/10.2337/db20-936-P
Published: 01 June 2020
View article titled, 936-P: Plasma Proteomic Profiling Delineates Treatment Efficacy of a GLP-1/GIP Coagonist in Female and Male Mice
Meeting Abstracts

1725-P: Viral Insulins as Agonists and Antagonists on Insulin/IGF-1 Receptors

FRANCOIS MOREAU, BRUNA BRANDAO, ESQ., CARLY CEDERQUIST, THIAGO M. BATISTA, RICHARD DIMARCHI, EMRAH ALTINDIS, C. RONALD KAHN
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1725-P
https://doi.org/10.2337/db20-1725-P
Published: 01 June 2020
View article titled, 1725-P: Viral Insulins as Agonists and Antagonists on Insulin/IGF-1 Receptors
Meeting Abstracts

1870-P: Glucagon-Receptor Signaling Reverses Hepatic Steatosis Independent of Leptin Receptor Expression

SHELLY NASON, TEAYOUN KIM, JESSICA P. ANTIPENKO, BRIAN FINAN, RICHARD DIMARCHI, KIRK M. HABEGGER
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1870-P
https://doi.org/10.2337/db19-1870-P
Published: 01 June 2019
View article titled, 1870-P: Glucagon-Receptor Signaling Reverses Hepatic Steatosis Independent of Leptin Receptor Expression
Meeting Abstracts

1965-P: Glucagon Receptor Agonism Stimulates Body Weight Loss in Antibiotic Treatment in Obese Mice

TEAYOUN KIM, JESSICA P. ANTIPENKO, SHELLY NASON, NATALIE PRESEDO, WILLIAM J. VAN DER POL, BRIAN FINAN, RICHARD DIMARCHI, CASEY D. MORROW, KIRK M. HABEGGER
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1965-P
https://doi.org/10.2337/db19-1965-P
Published: 01 June 2019
View article titled, 1965-P: Glucagon Receptor Agonism Stimulates Body Weight Loss in Antibiotic Treatment in Obese Mice
Journal Articles

Hepatic Glucagon Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents

Teayoun Kim, Cassie L. Holleman, Shelly Nason, Deanna M. Arble, Nickki Ottaway, Joseph Chabenne, Christine Loyd, Jeong-a Kim, Darleen Sandoval, Daniel J. Drucker, Richard DiMarchi, Diego Perez-Tilve, Kirk M. Habegger
Journal: Diabetes
Diabetes 2018;67(11):2157–2166
https://doi.org/10.2337/db18-0068
Published: 27 August 2018
View article titled, Hepatic Glucagon Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents
Open the PDF for Hepatic Glucagon Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents in another window
Includes: Supplementary data
Meeting Abstracts

Glucagon Regulates Energy Balance via FGF-21 Signaling in the Brain

SHELLY NASON, TEAYOUN KIM, JESSICA P. ANTIPENKO, JODI PAUL, BRIAN FINAN, RICHARD DIMARCHI, KIRK M. HABEGGER
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1806-P
https://doi.org/10.2337/db18-1806-P
Published: 01 July 2018
View article titled, Glucagon Regulates Energy Balance via FGF-21 Signaling in the Brain
Meeting Abstracts

Glucagon-Receptor Signaling Regulates Mitochondrial Bioenergetics via Hepatic Farnesol X Receptor

TEAYOUN KIM, SHELLY NASON, JESSICA P. ANTIPENKO, CATHERINA S. VESTRI, KELLEY SMITH-JOHNSTON, MARK E. PEPIN, ADAM R. WENDE, BRIAN FINAN, RICHARD DIMARCHI, DIEGO PEREZ-TILVE, DOUGLAS R. MOELLERING, KIRK M. HABEGGER
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1978-P
https://doi.org/10.2337/db18-1978-P
Published: 01 July 2018
View article titled, Glucagon-Receptor Signaling Regulates Mitochondrial Bioenergetics via Hepatic Farnesol X Receptor
Journal Articles

Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21

Teayoun Kim, Shelly Nason, Cassie Holleman, Mark Pepin, Landon Wilson, Taylor F. Berryhill, Adam R. Wende, Chad Steele, Martin E. Young, Stephen Barnes, Daniel J. Drucker, Brian Finan, Richard DiMarchi, Diego Perez-Tilve, Matthias Tschöp, Kirk M. Habegger
Journal: Diabetes
Diabetes 2018;67(9):1773–1782
https://doi.org/10.2337/db17-1502
Published: 20 June 2018
View article titled, Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21
Open the PDF for Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21 in another window
Includes: Supplementary data
Journal Articles

Single-Molecule Combinatorial Therapeutics for Treating Obesity and Diabetes

Matthias Tschöp, Richard DiMarchi
Journal: Diabetes
Diabetes 2017;66(7):1766–1769
https://doi.org/10.2337/dbi16-0068
Published: 15 June 2017
View article titled, Single-Molecule Combinatorial Therapeutics for Treating Obesity and Diabetes
Open the PDF for Single-Molecule Combinatorial Therapeutics for Treating Obesity and Diabetes in another window
Journal Articles

GLP-1/Glucagon Coagonism Restores Leptin Responsiveness in Obese Mice Chronically Maintained on an Obesogenic Diet

Christoffer Clemmensen, Joseph Chabenne, Brian Finan, Lorraine Sullivan, Katrin Fischer, Daniela Küchler, Laura Sehrer, Teja Ograjsek, Susanna M. Hofmann, Sonja C. Schriever, Paul T. Pfluger, Jason Pinkstaff, Matthias H. Tschöp, Richard DiMarchi, Timo D. Müller
Journal: Diabetes
Diabetes 2014;63(4):1422–1427
https://doi.org/10.2337/db13-1609
Published: 13 March 2014
View article titled, GLP-1/Glucagon Coagonism Restores Leptin Responsiveness in Obese Mice Chronically Maintained on an Obesogenic Diet
Open the PDF for GLP-1/Glucagon Coagonism Restores Leptin Responsiveness in Obese Mice Chronically Maintained on an Obesogenic Diet in another window
Includes: Supplementary data
Journal Articles

Both Acyl and Des-Acyl Ghrelin Regulate Adiposity and Glucose Metabolism via Central Nervous System Ghrelin Receptors

Kristy M. Heppner, Carolin L. Piechowski, Anne Müller, Nickki Ottaway, Stephanie Sisley, David L. Smiley, Kirk M. Habegger, Paul T. Pfluger, Richard DiMarchi, Heike Biebermann, Matthias H. Tschöp, Darleen A. Sandoval, Diego Perez-Tilve
Journal: Diabetes
Diabetes 2014;63(1):122–131
https://doi.org/10.2337/db13-0414
Published: 13 December 2013
View article titled, Both Acyl and Des-Acyl Ghrelin Regulate Adiposity and Glucose Metabolism via Central Nervous System Ghrelin Receptors
Open the PDF for Both Acyl and Des-Acyl Ghrelin Regulate Adiposity and Glucose Metabolism via Central Nervous System Ghrelin Receptors in another window
Journal Articles

Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling

Sarah H. Lockie, Kristy M. Heppner, Nilika Chaudhary, Joseph R. Chabenne, Donald A. Morgan, Christelle Veyrat-Durebex, Gayathri Ananthakrishnan, Françoise Rohner-Jeanrenaud, Daniel J. Drucker, Richard DiMarchi, Kamal Rahmouni, Brian J. Oldfield, Matthias H. Tschöp, Diego Perez-Tilve
Journal: Diabetes
Diabetes 2012;61(11):2753–2762
https://doi.org/10.2337/db11-1556
Published: 16 October 2012
View article titled, Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling
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Journal Articles

Reduction of Postprandial Hyperglycemia and Frequency of Hypoglycemia in IDDM Patients on Insulin-Analog Treatment

James H Anderson, Jr, Rocco L Brunelle, Veikko A Koivisto, Andreas Pfützner, Michael E Trautmann, Louis Vignati, Richard DiMarchi
Journal: Diabetes
Diabetes 1997;46(2):265–270
https://doi.org/10.2337/diab.46.2.265
Published: 01 February 1997
View article titled, Reduction of Postprandial Hyperglycemia and Frequency of Hypoglycemia in IDDM Patients on Insulin-Analog Treatment
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Journal Articles

Metabolic Effects of IGF-I in Diabetic Rats

Luciano Rossetti, Simona Frontoni, Richard Dimarchi, Ralph A DeFronzo, Andrea Giaccari
Journal: Diabetes
Diabetes 1991;40(4):444–448
https://doi.org/10.2337/diab.40.4.444
Published: 01 April 1991
View article titled, Metabolic Effects of IGF-I in Diabetic Rats
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Journal Articles

IGF-I–Stimulated Glucose Transport in Human Skeletal Muscle and IGF-I Resistance in Obesity and NIDDM

G Lynis Dohm, Charles W Elton, Madhu S Raju, Nitin D Mooney, Richard DiMarchi, Walter J Pories, Edward G Flickinger, Samuel M Atkinson, Jr, José F Caro
Journal: Diabetes
Diabetes 1990;39(9):1028–1032
https://doi.org/10.2337/diab.39.9.1028
Published: 01 September 1990
View article titled, IGF-I–Stimulated Glucose Transport in Human Skeletal Muscle and IGF-I Resistance in Obesity and NIDDM
Open the PDF for IGF-I–Stimulated Glucose Transport in Human Skeletal Muscle and IGF-I Resistance in Obesity and NIDDM in another window