1-9 of 9
Richard M. O’Brien
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Chronic Glucocorticoid Exposure Induced an S1PR2-RORγ Axis to Enhance Hepatic Gluconeogenesis in Male Mice

Rebecca A. Lee, Maggie Chang, Ariel Tsay, Yeong Rim Lee, Danielle Li, Nicholas Yiv, Sharon Tian, Michelle Zhao, Richard M. O’Brien, Jen-Chywan Wang
Journal: Diabetes
Diabetes 2023;72(11):1534–1546
https://doi.org/10.2337/db22-0605
Published: 08 August 2023
View articletitled, Chronic Glucocorticoid Exposure Induced an S1PR2-RORγ Axis to Enhance Hepatic Gluconeogenesis in Male Mice
Open the PDF for Chronic Glucocorticoid Exposure Induced an S1PR2-RORγ Axis to Enhance Hepatic Gluconeogenesis in Male Mice in another window
Journal Articles

An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets

Mark P. Keller, Emily M. Hawes, Kathryn L. Schueler, Donnie S. Stapleton, Kelly A. Mitok, Shane P. Simonett, James K. Oeser, Leesa L. Sampson, Alan D. Attie, Mark A. Magnuson, Richard M. O’Brien
Journal: Diabetes
Diabetes 2023;72(11):1621–1628
https://doi.org/10.2337/db23-0215
Published: 08 August 2023
View articletitled, An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets
Open the PDF for An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets in another window
Journal Articles

Novel Stable Isotope Analyses Demonstrate Significant Rates of Glucose Cycling in Mouse Pancreatic Islets

Martha L. Wall, Lynley D. Pound, Irina Trenary, Richard M. O’Brien, Jamey D. Young
Journal: Diabetes
Diabetes 2015;64(6):2129–2137
https://doi.org/10.2337/db14-0745
Published: 31 December 2014
View articletitled, Novel Stable Isotope Analyses Demonstrate Significant Rates of Glucose Cycling in Mouse Pancreatic Islets
Open the PDF for Novel Stable Isotope Analyses Demonstrate Significant Rates of Glucose Cycling in Mouse Pancreatic Islets in another window
Includes: Supplementary data
Journal Articles

G6PC2: A Negative Regulator of Basal Glucose-Stimulated Insulin Secretion

Lynley D. Pound, James K. Oeser, Tracy P. O’Brien, Yingda Wang, Chandler J. Faulman, Prasanna K. Dadi, David A. Jacobson, John C. Hutton, Owen P. McGuinness, Masakazu Shiota, Richard M. O’Brien
Journal: Diabetes
Diabetes 2013;62(5):1547–1556
https://doi.org/10.2337/db12-1067
Published: 16 April 2013
View articletitled, G6PC2: A Negative Regulator of Basal Glucose-Stimulated Insulin Secretion
Open the PDF for G6PC2: A Negative Regulator of Basal Glucose-Stimulated Insulin Secretion in another window
Journal Articles

Deletion of the G6pc2 Gene Encoding the Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Does Not Affect the Progression or Incidence of Type 1 Diabetes in NOD/ShiLtJ Mice

James K. Oeser, Vrajesh V. Parekh, Yingda Wang, Naresh K. Jegadeesh, Suparna A. Sarkar, Randall Wong, Catherine E. Lee, Lynley D. Pound, John C. Hutton, Luc Van Kaer, Richard M. O’Brien
Journal: Diabetes
Diabetes 2011;60(11):2922–2927
https://doi.org/10.2337/db11-0220
Published: 17 October 2011
View articletitled, Deletion of the G6pc2 Gene Encoding the Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Does Not Affect the Progression or Incidence of Type 1 Diabetes in NOD/ShiLtJ Mice
Open the PDF for Deletion of the G6pc2 Gene Encoding the Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Does Not Affect the Progression or Incidence of Type 1 Diabetes in NOD/ShiLtJ Mice in another window
Includes: Supplementary data
Journal Articles

Genetic and Functional Assessment of the Role of the rs13431652-A and rs573225-A Alleles in the G6PC2 Promoter That Are Strongly Associated With Elevated Fasting Glucose Levels

Nabila Bouatia-Naji, Amélie Bonnefond, Devin A. Baerenwald, Marion Marchand, Marco Bugliani, Piero Marchetti, François Pattou, Richard L. Printz, Brian P. Flemming, Obi C. Umunakwe, Nicholas L. Conley, Martine Vaxillaire, Olivier Lantieri, Beverley Balkau, Michel Marre, Claire Lévy-Marchal, Paul Elliott, Marjo-Riitta Jarvelin, David Meyre, Christian Dina, James K. Oeser, Philippe Froguel, Richard M. O'Brien
Journal: Diabetes
Diabetes 2010;59(10):2662–2671
https://doi.org/10.2337/db10-0389
Published: 09 July 2010
View articletitled, Genetic and Functional Assessment of the Role of the rs13431652-A and rs573225-A Alleles in the G6PC2 Promoter That Are Strongly Associated With Elevated Fasting Glucose Levels
Open the PDF for Genetic and Functional Assessment of the Role of the rs13431652-A and rs573225-A Alleles in the G6PC2 Promoter That Are Strongly Associated With Elevated Fasting Glucose Levels in another window
Includes: Supplementary data
Journal Articles

Long-Range Enhancers Are Required to Maintain Expression of the Autoantigen Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein in Adult Mouse Islets In Vivo

Yingda Wang, Brian P. Flemming, Cyrus C. Martin, Shelley R. Allen, Jay Walters, James K. Oeser, John C. Hutton, Richard M. O'Brien
Journal: Diabetes
Diabetes 2008;57(1):133–141
https://doi.org/10.2337/db07-0092
Published: 01 January 2008
View articletitled, Long-Range Enhancers Are Required to Maintain Expression of the Autoantigen Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein in Adult Mouse Islets In Vivo
Open the PDF for Long-Range Enhancers Are Required to Maintain Expression of the Autoantigen Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein in Adult Mouse Islets In Vivo in another window
Includes: Supplementary data
Journal Articles

The Proximal Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Autoantigen Promoter Is Sufficient to Initiate but not Maintain Transgene Expression in Mouse Islets in Vivo

Claudia Frigeri, Cyrus C. Martin, Christina A. Svitek, James K. Oeser, John C. Hutton, Maureen Gannon, Richard M. O’Brien
Journal: Diabetes
Diabetes 2004;53(7):1754–1764
https://doi.org/10.2337/diabetes.53.7.1754
Published: 01 July 2004
View articletitled, The Proximal Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Autoantigen Promoter Is Sufficient to Initiate but not Maintain Transgene Expression in Mouse Islets in Vivo
Open the PDF for The Proximal Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Autoantigen Promoter Is Sufficient to Initiate but not Maintain Transgene Expression in Mouse Islets in Vivo in another window
Journal Articles

Characterization of the Mouse Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Gene Promoter by In Situ Footprinting: Correlation With Fusion Gene Expression in the Islet-Derived βTC-3 and Hamster Insulinoma Tumor Cell Lines

Larry J. Bischof, Cyrus C. Martin, Christina A. Svitek, Beth T. Stadelmaier, Lauri A. Hornbuckle, Joshua K. Goldman, James K. Oeser, John C. Hutton, Richard M. O’Brien
Journal: Diabetes
Diabetes 2001;50(3):502–514
https://doi.org/10.2337/diabetes.50.3.502
Published: 01 March 2001
View articletitled, Characterization of the Mouse Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Gene Promoter by In Situ Footprinting: Correlation With Fusion Gene Expression in the Islet-Derived βTC-3 and Hamster Insulinoma Tumor Cell Lines
Open the PDF for Characterization of the Mouse Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Gene Promoter by In Situ Footprinting: Correlation With Fusion Gene Expression in the Islet-Derived βTC-3 and Hamster Insulinoma Tumor Cell Lines in another window